The human salivary microbiome exhibits temporal stability in bacterial diversity

The temporal variability of the human microbiome may be an important factor in determining its relationship with health and disease. In this study, the saliva of 40 participants was collected every 2 months over a one-year period to determine the temporal variability of the human salivary microbiome. Salivary pH and 16S rRNA gene copy number were measured for all participants, with the microbiome of 10 participants assessed through 16S rRNA amplicon sequencing. In February 2013, 16S rRNA gene copy number was significantly (P < 0.001) higher, with individual changes between time points significant (P = 0.003). Salivary pH levels were significantly (P < 0.001) higher in December 2012 than in October 2012 and February 2013, with significant (P < 0.001) individual variations seen throughout. Bacterial α-diversity showed significant differences between participants (P < 0.001), but not sampling periods (P = 0.801), and a significant positive correlation with salivary pH (R(2) = 7.8%; P = 0.019). At the phylum level, significant differences were evident between participants in the Actinobacteria (P < 0.001), Bacteroidetes (P < 0.001), Firmicutes (P = 0.008), Fusobacteria (P < 0.001), Proteobacteria (P < 0.001), Synergistetes (P < 0.001) and Spirochaetes (P = 0.003) phyla. This study charted the temporal variability of the salivary microbiome, suggesting that bacterial diversity is stable, but that 16S rRNA gene copy number may be subject to seasonal flux

Energy density of foods and beverages in the Australian food supply: influence of macronutrients and comparison to dietary intake.

OBJECTIVES: The energy density (ED) of the diet is considered an important determinant of total energy intake and thus energy balance and weight change. We aimed to compare relationships between ED and macronutrient content in individual food and beverage items as well as population diet in a typical Western country. DESIGN: Nutrient data for 3673 food items and 247 beverage items came from the Australian Food and Nutrient database (AusNut). Food and beverage intake data came from the 1995 Australian National Nutrition Survey (a 24-h dietary recall survey in 13 858 people over the age of 2). Relationships between ED and macronutrient and water content were analysed by linear regression with 95% prediction bands. RESULTS: For both individual food items and population food intake, there was a positive relationship between ED and percent energy as fat and negative relationships between ED and percent energy as carbohydrate and percent water by weight. In all cases, there was close agreement between the slopes of the regression lines between food items and dietary intake. There were no clear relationships between ED and macronutrient content for beverage items. Carbohydrate (mostly sucrose) contributed 91, 47, and 25% of total energy for sugar-based, fat-based, and alcohol-based beverages respectively. CONCLUSIONS: The relationship between ED and fat content of foods holds true across both population diets and individual food items available in the food supply in a typical Western country such as Australia. As high-fat diets are associated with a high BMI, population measures with an overall aim of reducing the ED of diets may be effective in mediating the growing problem of overweight and obesity

The Mountain of a Thousand Holes: Shipwreck Traditions and Treasure Hunting on Oregon\u27s North Coast

“Euro-Americans in coastal communities conflated and amplified Native American oral traditions of shipwrecks in Tillamook County, increasingly focusing on buried treasure,” write authors Cameron La Follette, Dennis Griffin and Douglas Deur. In this article, the authors trace the Euro-American blending of Native oral tradition with romances and adventure tales that helped create the “legends contributing to Neahkahnie [Mountain]\u27s reputation as Oregon\u27s treasure-seeking haven.” They also examine the history of treasure-seeking in the area and describe the escalating conflict between Oregon\u27s treasure-hunting statute and cultural resources protection laws, which led finally to statutory repeal that ended all treasure-hunting on state lands. While treasure hunting is no longer allowed in Oswald West State Park where Neahkahnie Mountain is located, the “Beeswax Wreck” lore continues to fascinate visitors to the north Oregon coast

The Galleon Cargo: Accounts in the Colonial Archives

Much of the debris that has washed up on the shores of the northern Oregon coast for centuries were mainstays of Spanish trade carried as cargo across the world on Manila galleons. Both Native people and Euro-Americans have recovered large beeswax chunks, lending to the lore of the “Beeswax Wreck,” as well as Chinese blue-and-white porcelain fragments. In this article, Cameron La Follette and Douglas Deur describe research findings about cargo on the Santo Cristo de Burgos and similar Manila galleons, including the San Francisco Xavier of 1705, the previous favored candidate for the Oregon wreck. La Follette and Deur located probable matches for the shippers\u27 identities of four shipper\u27s marks found on Oregon beeswax chunks. According to La Follette and Deur, “in addition to trade goods, the Santo Cristo de Burgos carried a cargo of liquid mercury,” which was essential for refining silver ore from South American mines used to make coins that fueled the Spanish empire and the Manila trade itself. The article contains a partial cargo list for the 1693 Santo Cristo de Burgos voyage and a special digital appendix with the full cargo manifest for the 1701 San Francisco Xavier

The cross helicity at the solar surface by simulations and observations

The quasilinear mean-field theory for driven MHD turbulence leads to the result that the observed cross helicity may directly yield the magnetic eddy diffusivity \eta_{T} of the quiet Sun. In order to model the cross helicity at the solar surface, magnetoconvection under the presence of a vertical large-scale magnetic field is simulated with the nonlinear MHD code NIRVANA. The very robust result of the calculations is that \simeq 2 independent of the applied magnetic field amplitude. The correlation coefficient for the cross helicity is about 10%. Of similar robustness is the finding that the rms value of the magnetic perturbations exceeds the mean-field amplitude (only) by a factor of five. The characteristic helicity speed u_{\eta} as the ratio of the eddy diffusivity and the density scale height for an isothermal sound velocity of 6.6 km/s proves to be 1 km/s for weak fields. This value well coincides with empirical results obtained from the data of the HINODE satellite and the Swedish 1-m Solar Telescope (SST) providing the cross helicity component . Both simulations and observations thus lead to a numerical value of \eta_{T} \simeq 10^12 cm^2 /s as characteristic for the surface of the quiet Sun.Comment: 6 pages, 6 figure

Multimodal agent interfaces and system architectures for health and fitness companions

Multimodal conversational spoken dialogues using physical and virtual agents provide a potential interface to motivate and support users in the domain of health and fitness. In this paper we present how such multimodal conversational Companions can be implemented to support their owners in various pervasive and mobile settings. In particular, we focus on different forms of multimodality and system architectures for such interfaces

Community Voices: A Participatory Approach for Measuring Resident Perceptions of Police and Policing

Community Voices, a participatory research project, aimed to change the ways residents are heard and police are held accountable. The central tenet of the project was that creating an authentic representation of community sentiment towards the police has the capacity to reshape power dynamics between law enforcement and marginalized communities. This brief provides an overview of the pilot of Community Voices in Austin, Texas, discusses its impact, and includes attachments that provide more extensive details about the findings and related products

The Updated Commentary on the First Geneva Convention – A New Tool for Generating Respect for International Humanitarian Law

Since their publication in the 1950s and the 1980s respectively, the Commentaries on the Geneva Conventions of 1949 and their Additional Protocols of 1977 have become a major reference for the application and interpretation of these treaties. The International Committee of the Red Cross (ICRC), together with a team of renowned experts, is currently updating these Commentaries in order to document developments and provide up-to-date interpretations. The work on the first updated Commentary, the Commentary on the First Geneva Convention relating to the protection of the wounded and sick in the armed forces, has already been finalized. This article provides an overview of the methodology and process of the update and summarizes the main evolutions in the interpretation of the treaty norms reflected in the updated commentary