Quark-Gluon Plasma Fireball

Lattice-QCD results provide an opportunity to model, and extrapolate to finite baryon density, the properties of the quark-gluon plasma (QGP). Upon fixing the scale of the thermal coupling constant and vacuum energy to the lattice data, the properties of resulting QGP equations of state (EoS) are developed. We show that the physical properties of the dense matter fireball formed in heavy ion collision experiments at CERN-SPS are well described by the QGP-EoS we presented. We also estimate the properties of the fireball formed in early stages of nuclear collision, and argue that QGP formation must be expected down to 40A GeV in central Pb--Pb interactions.Comment: 10 pages, 9 postscript figures, 1 table, uses revtex, V3: introduced difference between n_f and n_s; fireball restframe energy corrected, references added. Publisched version in press Phys. Rev.

Chemical equilibration and thermal dilepton production from the quark gluon plasma at finite baryon density

The chemical equilibration of a highly unsaturated quark-gluon plasma has been studied at finite baryon density. It is found that in the presence of small amount of baryon density, the chemical equilibration for gluon becomes slower and the temperature decreases less steeply as compared to the baryon free plasma. As a result, the space time integrated yield of dilepton is enhanced if the initial temperature of the plasma is held fixed. Even at a fixed initial energy density, the suppression of the dilepton yields at higher baryo-chemical potential is compensated, to a large extent, by the slow cooling of the plasma.Comment: Latex, 19 pages, 8 postscript figures. To appear in Phys. Rev.

A first order transition and parity violation in a color superconductor

In cold, dense quark matter, quarks of different flavor can form Cooper pairs which are anti-triplets under color and have total spin J=0. The transition to a phase where strange quarks condense with either up or down quarks is driven first order by the Coleman-Weinberg mechanism. At densities sufficiently high to (effectively) restore the axial U(1) symmetry, then relative to the ordinary vacuum, the condensation of up with down quarks (effectively) breaks parity spontaneously.Comment: 4 pages, ReVTeX, final versio

Color superconductivity in weak coupling

We derive perturbatively the gap equations for a color-superconducting condensate with total spin J=0 in dense QCD. At zero temperature, we confirm the results of Son for the dependence of the condensate on the coupling constant, and compute the prefactor to leading logarithmic accuracy. At nonzero temperature, we find that to leading order in weak coupling, the temperature dependence of the condensate is identical to that in BCS-like theories. The condensates for total spin J=1 are classified; to leading logarithmic accuracy these condensates are of the same order as those of spin J=0.Comment: 30 pages, 3 figures, RevTeX, epsf and psfig style files require

"Treatment is of primary importance, and social assistance is secondary": A qualitative study on the organisation of tuberculosis (TB) care and patients' experience of starting and staying on TB treatment in Riga, Latvia

From PLOS via Jisc Publications Router.History: collection 2018, received 2018-01-24, accepted 2018-08-30, epub 2018-10-17Background Vulnerable individuals with tuberculosis (TB) struggle to access and stay on treatment. While patient-related and social barriers to TB treatment adherence are well documented, less is known about how the organisation and delivery of TB care influences adherence behaviour. Aim To examine the influence of TB service organisation and culture on patients’ experience of starting and staying on treatment in Riga, Latvia. Methods An intervention package to support adherence to TB treatment amongst vulnerable patients in Riga, Latvia was piloted between August 2016 and March 2017. Qualitative observations (5), interviews with staff (20) and with TB patients (10) were conducted mid-way and at the end of the intervention to understand perceptions, processes, and experiences of TB care. Results The organisation of TB services is strongly influenced by a divide between medical and social aspects of TB care. Communication and care practices are geared towards addressing individual risk factors for non-adherence rather than the structural vulnerabilities that patients experience in accessing care. Support for vulnerable patients is limited because of standardised programmatic approaches, resource constraints and restricted job descriptions for non-medical staff. Conclusion Providing support for vulnerable patients is challenged in this setting by the strict division between medical and social aspects of TB care, and the organisational focus on patient-related rather than systems-related barriers to access and adherence. Potential systems interventions include the introduction of multi-disciplinary approaches and teams in TB care, strengthening patient literacy at the point of treatment initiation, as well as stronger linkages with social care organisations.Funder: European Centre for Disease Prevention and Control, funder-id: http://dx.doi.org/10.13039/501100000805, Grants: OCS-2015-0UT-2900-MCSaAI13pubpub1

Two lectures on color superconductivity

The first lecture provides an introduction to the physics of color superconductivity in cold dense quark matter. The main color superconducting phases are briefly described and their properties are listed. The second lecture covers recent developments in studies of color superconducting phases in neutral and beta-equilibrated matter. The properties of gapless color superconducting phases are discussed.Comment: 56 pages, 9 figures. Minor corrections and references added. Lectures delivered at the IARD 2004 conference, Saas Fee, Switzerland, June 12 - 19, 2004, and at the Helmholtz International Summer School and Workshop on Hot points in Astrophysics and Cosmology, JINR, Dubna, Russia, August 2 - 13, 200

Multidrug resistant pulmonary tuberculosis treatment regimens and patient outcomes: an individual patient data meta-analysis of 9,153 patients.

Treatment of multidrug resistant tuberculosis (MDR-TB) is lengthy, toxic, expensive, and has generally poor outcomes. We undertook an individual patient data meta-analysis to assess the impact on outcomes of the type, number, and duration of drugs used to treat MDR-TB

Damping rates of hard momentum particles in a cold ultrarelativistic plasma

We compute the damping rates of one-particle excitations in a cold ultrarelativistic plasma to leading order in the coupling constant e for three types of interaction: Yukawa coupling to a massless scalar boson, QED and QCD. Damping rates of charged particles in QED and QCD are of order e^3 mu, while damping rates of other particles are of order e^4 mu or e^4 mu log(1/e). We find that the damping rate of an electron or of a quark is constant far from the Fermi surface, and decreases linearly with the excitation energy close to the Fermi surface. This unusual behavior is attributed to the long-range magnetic interactions.Comment: 40 pages, Revtex, 17 Postscript figures (included). Revised versio

What scans we will read: imaging instrumentation trends in clinical oncology

Oncological diseases account for a significant portion of the burden on public healthcare systems with associated costs driven primarily by complex and long-lasting therapies. Through the visualization of patient-specific morphology and functional-molecular pathways, cancerous tissue can be detected and characterized non- invasively, so as to provide referring oncologists with essential information to support therapy management decisions. Following the onset of stand-alone anatomical and functional imaging, we witness a push towards integrating molecular image information through various methods, including anato-metabolic imaging (e.g., PET/ CT), advanced MRI, optical or ultrasound imaging. This perspective paper highlights a number of key technological and methodological advances in imaging instrumentation related to anatomical, functional, molecular medicine and hybrid imaging, that is understood as the hardware-based combination of complementary anatomical and molecular imaging. These include novel detector technologies for ionizing radiation used in CT and nuclear medicine imaging, and novel system developments in MRI and optical as well as opto-acoustic imaging. We will also highlight new data processing methods for improved non-invasive tissue characterization. Following a general introduction to the role of imaging in oncology patient management we introduce imaging methods with well-defined clinical applications and potential for clinical translation. For each modality, we report first on the status quo and point to perceived technological and methodological advances in a subsequent status go section. Considering the breadth and dynamics of these developments, this perspective ends with a critical reflection on where the authors, with the majority of them being imaging experts with a background in physics and engineering, believe imaging methods will be in a few years from now. Overall, methodological and technological medical imaging advances are geared towards increased image contrast, the derivation of reproducible quantitative parameters, an increase in volume sensitivity and a reduction in overall examination time. To ensure full translation to the clinic, this progress in technologies and instrumentation is complemented by progress in relevant acquisition and image-processing protocols and improved data analysis. To this end, we should accept diagnostic images as “data”, and – through the wider adoption of advanced analysis, including machine learning approaches and a “big data” concept – move to the next stage of non-invasive tumor phenotyping. The scans we will be reading in 10 years from now will likely be composed of highly diverse multi- dimensional data from multiple sources, which mandate the use of advanced and interactive visualization and analysis platforms powered by Artificial Intelligence (AI) for real-time data handling by cross-specialty clinical experts with a domain knowledge that will need to go beyond that of plain imaging