150 research outputs found
Plasma measurements conducted in the vincinity of Venus on the spacecraft VENERA-4
Plasma flux measurements in vicinity of Venus by charged particle traps on Venera-4 spacecraf
Comparison of Certain Results of Simultaneous Measurements of Solar Wind Characteristics on Spacecrafts ''Venera-3'' and ''Pioneer-6''
Ion concentration, ion velocity, and other solar wind characteristics measured simultaneously aboard spacecraf
Signs of crossing by the moon of the earth's magnetosphere tail according to data of charged particle traps on the first artificial satellite of the moon /Luna-10/
Space probe charged particle data evidence for moon crossing of Earth magnetospheric tai
Regge Behavior of DIS Structure Functions
Building on previous works of the mid 1960's, we construct an integral
equation for forward elastic scattering (t=0) at arbitrary virtuality Q^2 and
large s=W^2. This equation sums the ladder production of massless intermediate
bosons to all orders, and the solution exhibits Regge behavior. The equation is
used to study scattering in a simple chi^2 phi scalar theory, where it is
solved appoximately and applied to the study of DIS at small x. We find that
the model can naturally describe the quark distribution in both the large x
region and the small x region dominated by Reggeon exchange.Comment: 13 pages with 5 figure
Off-forward parton distributions and Shuvaev's transformations
We review Shuvaev's transformations, that relate off-forward parton
distributions (OFPDs) to so-called effective forward parton distributions
(EFPDs). The latter evolve like conventional forward partons. We express
nonforward amplitudes, depending on OFPDs, directly in terms of EFPDs and
construct a model for the EFPDs, which allows to consistently express them in
terms of the conventional forward parton distributions and nucleon form
factors. Our model is self-consistent for arbitrary x, xi, mu, and t.Comment: 13 pages, 7 eps-figures, LaTeX2e, added references, corrected typo
Skewed parton distributions and the scale dependence of the transverse size parameter
We discuss the scale dependence of a skewed parton distribution of the pion
obtained from a generalized light-cone wave function overlap formula. Using a
simple ansatz for the transverse momentum dependence of the light-cone wave
function and restricting ourselves to the case of a zero skewedness parameter,
the skewed parton distribution can be expressed through an ordinary parton
distribution multiplied by an exponential function. Matching the generalized
and ordinary DGLAP evolution equations of the skewed and ordinary parton
distributions, respectively, we derive a constraint for the scale dependence of
the transverse size parameter, which describes the width of the pion wave
function in transverse momentum space. This constraint has implications for the
Fock state probability and valence distribution. We apply our results to the
pion form factor.Comment: 10 pages, 4 figures; version to appear in Phys. Rev. D; Refs. added,
new discussion of results for pion form factor in view of new dat
DVCS amplitude at tree level: Transversality, twist-3, and factorization
We study the virtual Compton amplitude in the generalized Bjorken region (q^2
-> Infinity, t small) in QCD by means of a light-cone expansion of the product
of e.m. currents in string operators in coordinate space. Electromagnetic gauge
invariance (transversality) is maintained by including in addition to the
twist-2 operators 'kinematical' twist-3 operators which appear as total
derivatives of twist-2 operators. The non-forward matrix elements of the
elementary twist-2 operators are parametrized in terms of two-variable spectral
functions (double distributions), from which twist-2 and 3 skewed distributions
are obtained through reduction formulas. Our approach is equivalent to a
Wandzura-Wilczek type approximation for the twist-3 skewed distributions. The
resulting Compton amplitude is manifestly transverse up to terms of order
t/q^2. We find that in this approximation the tensor amplitude for longitudinal
polarization of the virtual photon is finite, while the one for transverse
polarization contains a divergence already at tree level. However, this
divergence has zero projection on the polarization vector of the final photon,
so that the physical helicity amplitudes are finite.Comment: 34 pages, revtex, 1 eps figure included using epsf. Misprints
corrected, one reference adde
ΠΠΎΠΌΡΠ½ΠΎ-ΡΠ΅Π°ΠΊΡΡΡ ΡΠ·Π°ΡΠΈΠ½ΡΠ² Π· 5-Π°ΠΌΡΠ½ΠΎΠΏΡΡΠ°Π·ΠΎΠ»Π°ΠΌΠΈ ΡΠ° 2,2-Π΄ΠΈΠΌΠ΅ΡΠΈΠ»-1,3-Π΄ΡΠΎΠΊΡΠ°Π½-4,6-Π΄ΡΠΎΠ½ΠΎΠΌ
Aim. To determine the direction of the interaction of isatins with 5-amino-pyrazoles and 2,2-dimethyl-1,3-dioxane-4,6-dione under different conditions.Results and discussion. The domino-reactions of isatins, 5-aminopyrazoles and 2,2-dimethyl-1,3-dioxane-4,6-dione (Meldrumβs acid) in the alcoholic medium are completed by formation of a mixture of pyrazolo[3,4-b]pyridine-4-spiroindolinones and 3-(5-aminopyrazol-3-yl)-3-hydroxy-2-oxindolines with the predominant content of spiro compounds. 3-(5-Aminopyrazol-4-yl)-3-hydroxy-2-oxindolines may turn into pyrazolo[3,4-b]pyridine-4-spiroindolinones very slowly only as a result of retrograde fragmentation to isatin and aminopyrazole in the presence of Meldrumβs acid.Experimental part. The mixtures of pyrazolo[3,4-b]pyridine-4-spiroindolinones and 3-(5-aminopyrazol-3-yl)-3-hydroxy-2-oxindolines separated by crystallization were obtained by boiling in methanol of the equimolar quantity of isatins, 5-aminopyrazoles and Meldrumβs acids. The yield for spiro compounds is 26-82 %, and for 3-(5-aminopyrazole-3-yl)-3-hydroxy-2-oxindolines it is 5-23 %. The transformation of the latter into the spiro compound in the presence of Meldrumβs acid occurs with prolonged boiling in the alcoholic medium and is accompanied with extremely low yields. The structure of all compounds synthesized has been proven by 1H NMR, mass spectra and elemental analysis.Conclusions. It has been found that in the three-component reactions of isatins, 5-aminopyrazoles and 2,2-dimethyl-1,3-dioxane-4,6-dione there are two competing directions of the interaction of isatin with nucleophiles. One of them is the nucleophilic addition of the C4 reaction center of aminopyrazole to the carbonyl group of isatin, which results in 3-(5-aminopyrazol-4-yl)-3-hydroxy-2-oxidolines. Another one is the Knoevenagel condensation of isatin with dioxane-4,6-dione β a domino process that starts formation of the predominant reaction products β pyrazolo[3,4-b]pyridine-4-spiroindolinones.Π¦Π΅Π»Ρ ΡΠ°Π±ΠΎΡΡ β ΡΡΡΠ°Π½ΠΎΠ²ΠΈΡΡ Π½Π°ΠΏΡΠ°Π²Π»Π΅Π½Π½ΠΎΡΡΡ Π²Π·Π°ΠΈΠΌΠΎΠ΄Π΅ΠΉΡΡΠ²ΠΈΡ ΠΈΠ·Π°ΡΠΈΠ½ΠΎΠ² Ρ 5-Π°ΠΌΠΈΠ½ΠΎΠΏΠΈΡΠ°Π·ΠΎΠ»Π°ΠΌΠΈ ΠΈ 2,2-Π΄ΠΈΠΌΠ΅ΡΠΈΠ»-1,3-Π΄ΠΈΠΎΠΊΡΠ°Π½-4,6-Π΄ΠΈΠΎΠ½ΠΎΠΌ Π² ΡΠ°Π·Π½ΡΡ
ΡΡΠ»ΠΎΠ²ΠΈΡΡ
.Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ ΠΈ ΠΈΡ
ΠΎΠ±ΡΡΠΆΠ΄Π΅Π½ΠΈΠ΅. ΠΠΎΠΌΠΈΠ½ΠΎ-ΡΠ΅Π°ΠΊΡΠΈΠΈ ΠΈΠ·Π°ΡΠΈΠ½ΠΎΠ², 5-Π°ΠΌΠΈΠ½ΠΎΠΏΠΈΡΠ°Π·ΠΎΠ»ΠΎΠ² ΠΈ 2,2-Π΄ΠΈΠΌΠ΅ΡΠΈΠ»-1,3-Π΄ΠΈΠΎΠΊΡΠ°Π½-4,6-Π΄ΠΈΠΎΠ½Π° (ΠΊΠΈΡΠ»ΠΎΡΡ ΠΠ΅Π»ΡΠ΄ΡΡΠΌΠ°) Π² ΡΠΏΠΈΡΡΠΎΠ²ΠΎΠΉ ΡΡΠ΅Π΄Π΅ Π·Π°Π²Π΅ΡΡΠ°ΡΡΡΡ ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΠ΅ΠΌ ΡΠΌΠ΅ΡΠ΅ΠΉ ΠΏΠΈΡΠ°Π·ΠΎΠ»ΠΎ[3,4-b]ΠΏΠΈΡΠΈΠ΄ΠΈΠ½-4-ΡΠΏΠΈΡΠΎΠΈΠ½Π΄ΠΎΠ»ΠΈΠ½ΠΎΠ½ΠΎΠ² ΠΈ 3-(5-Π°ΠΌΠΈΠ½ΠΎΠΏΠΈΡΠ°Π·ΠΎΠ»-3-ΠΈΠ»)-3-Π³ΠΈΠ΄ΡΠΎΠΊΡΠΈ-2-ΠΎΠΊΡΠΈΠ½Π΄ΠΎΠ»ΠΈΠ½ΠΎΠ² Ρ ΠΏΡΠ΅ΠΎΠ±Π»Π°Π΄Π°ΡΡΠΈΠΌ ΡΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΠ΅ΠΌ ΡΠΏΠΈΡΠΎ-ΡΠΎΠ΅Π΄ΠΈΠ½Π΅Π½ΠΈΠΉ. 3-(5-ΠΠΌΠΈΠ½ΠΎΠΏΠΈΡΠ°Π·ΠΎΠ»-4-ΠΈΠ»)-3-Π³ΠΈΠ΄ΡΠΎΠΊΡΠΈ-2-ΠΎΠΊΡΠΈΠ½Π΄ΠΎΠ»ΠΈΠ½Ρ Π»ΠΈΡΡ Π² ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠ΅ ΡΠ΅ΡΡΠΎΡΠ°ΡΠΏΠ°Π΄Π° Π½Π° ΠΈΡΡ
ΠΎΠ΄Π½ΡΠ΅ ΠΈΠ·Π°ΡΠΈΠ½ ΠΈ Π°ΠΌΠΈΠ½ΠΎΠΏΠΈΡΠ°Π·ΠΎΠ» Π² ΠΏΡΠΈΡΡΡΡΡΠ²ΠΈΠΈ ΠΊΠΈΡΠ»ΠΎΡΡ ΠΠ΅Π»ΡΠ΄ΡΡΠΌΠ° ΠΌΠΎΠ³ΡΡ ΠΎΡΠ΅Π½Ρ ΠΌΠ΅Π΄Π»Π΅Π½Π½ΠΎ Ρ Π½ΠΈΠ·ΠΊΠΈΠΌΠΈ Π²ΡΡ
ΠΎΠ΄Π°ΠΌΠΈ ΠΏΡΠ΅Π²ΡΠ°ΡΠ°ΡΡΡΡ Π² ΠΏΠΈΡΠ°Π·ΠΎΠ»ΠΎ[3,4-b]ΠΏΠΈΡΠΈΠ΄ΠΈΠ½-4-ΡΠΏΠΈΡΠΎΠΈΠ½Π΄ΠΎΠ»ΠΈΠ½ΠΎΠ½Ρ.ΠΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ°Π»ΡΠ½Π°Ρ ΡΠ°ΡΡΡ. ΠΠΈΠΏΡΡΠ΅Π½ΠΈΠ΅ΠΌ Π² ΠΌΠ΅ΡΠ°Π½ΠΎΠ»Π΅ ΡΠΊΠ²ΠΈΠΌΠΎΠ»ΡΠ½ΡΡ
ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ² ΠΈΠ·Π°ΡΠΈΠ½ΠΎΠ², 5-Π°ΠΌΠΈΠ½ΠΎΠΏΠΈΡΠ°Π·ΠΎΠ»ΠΎΠ² ΠΈ ΠΊΠΈΡΠ»ΠΎΡΡ ΠΠ΅Π»ΡΠ΄ΡΡΠΌΠ° ΠΏΠΎΠ»ΡΡΠ΅Π½Ρ ΡΠΌΠ΅ΡΠΈ ΠΏΠΈΡΠ°Π·ΠΎΠ»ΠΎ[3,4-b]ΠΏΠΈΡΠΈΠ΄ΠΈΠ½-4-ΡΠΏΠΈΡΠΎΠΈΠ½Π΄ΠΎΠ»ΠΈΠ½ΠΎΠ½ΠΎΠ² ΠΈ 3-(5-Π°ΠΌΠΈΠ½ΠΎΠΏΠΈΡΠ°Π·ΠΎΠ»-3-ΠΈΠ»)-3-Π³ΠΈΠ΄ΡΠΎΠΊΡΠΈ-2-ΠΎΠΊΡΠΈΠ½Π΄ΠΎΠ»ΠΈΠ½ΠΎΠ², ΠΊΠΎΡΠΎΡΡΠ΅ ΡΠ°Π·Π΄Π΅Π»Π΅Π½Ρ ΠΊΡΠΈΡΡΠ°Π»Π»ΠΈΠ·Π°ΡΠΈΠ΅ΠΉ. ΠΡΡ
ΠΎΠ΄ ΡΠΏΠΈΡΠΎ-ΡΠΎΠ΅Π΄ΠΈΠ½Π΅Π½ΠΈΠΉ ΡΠΎΡΡΠ°Π²Π»ΡΠ΅Ρ 26-82 %, Π° 3-(5-Π°ΠΌΠΈΠ½ΠΎΠΏΠΈΡΠ°Π·ΠΎΠ»-3-ΠΈΠ»)-3-Π³ΠΈΠ΄ΡΠΎΠΊΡΠΈ-2-ΠΎΠΊΡΠΈΠ½Π΄ΠΎΠ»ΠΈΠ½ΠΎΠ² β 5-23 %. ΠΡΠ΅Π²ΡΠ°ΡΠ΅Π½ΠΈΠ΅ ΠΏΠΎΡΠ»Π΅Π΄Π½ΠΈΡ
Π² ΠΏΡΠΈΡΡΡΡΡΠ²ΠΈΠΈ ΠΊΠΈΡΠ»ΠΎΡΡ ΠΠ΅Π»ΡΠ΄ΡΡΠΌΠ° Π² ΡΠΏΠΈΡΠΎ-ΡΠΎΠ΅Π΄ΠΈΠ½Π΅Π½ΠΈΡ ΠΏΡΠΎΠΈΡΡ
ΠΎΠ΄ΠΈΡ ΠΏΡΠΈ Π΄Π»ΠΈΡΠ΅Π»ΡΠ½ΠΎΠΌ ΠΊΠΈΠΏΡΡΠ΅Π½ΠΈΠΈ Π² ΡΠΏΠΈΡΡΠΎΠ²ΠΎΠΉ ΡΡΠ΅Π΄Π΅ ΠΈ ΡΠΎΠΏΡΠΎΠ²ΠΎΠΆΠ΄Π°Π΅ΡΡΡ ΠΊΡΠ°ΠΉΠ½Π΅ Π½ΠΈΠ·ΠΊΠΈΠΌΠΈ Π²ΡΡ
ΠΎΠ΄Π°ΠΌΠΈ. Π‘ΡΡΠΎΠ΅Π½ΠΈΠ΅ ΠΈ ΡΠΎΡΡΠ°Π² Π²ΡΠ΅Ρ
ΡΠΈΠ½ΡΠ΅Π·ΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
ΡΠΎΠ΅Π΄ΠΈΠ½Π΅Π½ΠΈΠΉ Π΄ΠΎΠΊΠ°Π·Π°Π½Ρ Π΄Π°Π½Π½ΡΠΌΠΈ Π―ΠΠ 1Π, ΠΌΠ°ΡΡ-ΡΠΏΠ΅ΠΊΡΡΠΎΠ² ΠΈ ΡΠ»Π΅ΠΌΠ΅Π½ΡΠ½ΡΠΌ Π°Π½Π°Π»ΠΈΠ·ΠΎΠΌ.ΠΡΠ²ΠΎΠ΄Ρ. Π£ΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ΠΎ, ΡΡΠΎ Π² ΡΡΠ΅Ρ
ΠΊΠΎΠΌΠΏΠΎΠ½Π΅Π½ΡΠ½ΡΡ
ΡΠ΅Π°ΠΊΡΠΈΡΡ
ΠΈΠ·Π°ΡΠΈΠ½ΠΎΠ², 5-Π°ΠΌΠΈΠ½ΠΎΠΏΠΈΡΠ°Π·ΠΎΠ»ΠΎΠ² ΠΈ 2,2-Π΄ΠΈΠΌΠ΅ΡΠΈΠ»-1,3-Π΄ΠΈΠΎΠΊΡΠ°Π½-4,6-Π΄ΠΈΠΎΠ½Π° ΡΠ΅Π°Π»ΠΈΠ·ΡΡΡΡΡ Π΄Π²Π° ΠΊΠΎΠ½ΠΊΡΡΠΈΡΡΡΡΠΈΡ
Π½Π°ΠΏΡΠ°Π²Π»Π΅Π½ΠΈΡ Π²Π·Π°ΠΈΠΌΠΎΠ΄Π΅ΠΉΡΡΠ²ΠΈΡ ΠΈΠ·Π°ΡΠΈΠ½Π° Ρ Π½ΡΠΊΠ»Π΅ΠΎΡΠΈΠ»Π°ΠΌΠΈ. ΠΠ΄Π½ΠΎ ΠΈΠ· Π½ΠΈΡ
β Π½ΡΠΊΠ»Π΅ΠΎΡΠΈΠ»ΡΠ½ΠΎΠ΅ ΠΏΡΠΈΡΠΎΠ΅Π΄ΠΈΠ½Π΅Π½ΠΈΠ΅ Π‘4 ΡΠ΅Π°ΠΊΡΠΈΠΎΠ½Π½ΠΎΠ³ΠΎ ΡΠ΅Π½ΡΡΠ° Π°ΠΌΠΈΠ½ΠΎΠΏΠΈΡΠ°Π·ΠΎΠ»Π° ΠΊ ΠΊΠ°ΡΠ±ΠΎΠ½ΠΈΠ»ΡΠ½ΠΎΠΉ Π³ΡΡΠΏΠΏΠ΅ ΠΈΠ·Π°ΡΠΈΠ½Π° ΠΏΡΠΈΠ²ΠΎΠ΄ΠΈΡ ΠΊ 3-(5-Π°ΠΌΠΈΠ½ΠΎΠΏΠΈΡΠ°Π·ΠΎΠ»-4-ΠΈΠ»)-3-Π³ΠΈΠ΄ΡΠΎΠΊΡΠΈ-2-ΠΎΠΊΡΠΈΠ½Π΄ΠΎΠ»ΠΈΠ½Π°ΠΌ. Π Π²ΡΠΎΡΠΎΠ΅ β ΠΊΠΎΠ½Π΄Π΅Π½ΡΠ°ΡΠΈΡ ΠΈΠ·Π°ΡΠΈΠ½Π° Ρ Π΄ΠΈΠΎΠΊΡΠ°Π½-4,6-Π΄ΠΈΠΎΠ½ΠΎΠΌ ΠΏΠΎ ΠΠ½Π΅Π²Π΅Π½Π°Π³Π΅Π»Ρ ΠΈΠ½ΠΈΡΠΈΠΈΡΡΠ΅Ρ Π΄ΠΎΠΌΠΈΠ½ΠΎ-ΠΏΡΠΎΡΠ΅ΡΡ, ΠΊΠΎΡΠΎΡΡΠΉ Π·Π°Π²Π΅ΡΡΠ°Π΅ΡΡΡ ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΠ΅ΠΌ ΠΎΡΠ½ΠΎΠ²Π½ΡΡ
ΠΏΡΠΎΠ΄ΡΠΊΡΠΎΠ² ΡΠ΅Π°ΠΊΡΠΈΠΈ β ΠΏΠΈΡΠ°Π·ΠΎΠ»ΠΎ[3,4-b]ΠΏΠΈΡΠΈΠ΄ΠΈΠ½-4-ΡΠΏΠΈΡΠΎΠΈΠ½Π΄ΠΎΠ»ΠΈΠ½ΠΎΠ½ΠΎΠ².ΠΠ΅ΡΠ° ΡΠΎΠ±ΠΎΡΠΈ β Π²ΡΡΠ°Π½ΠΎΠ²ΠΈΡΠΈ Π½Π°ΠΏΡΠ°Π²Π»Π΅Π½ΡΡΡΡ Π²Π·Π°ΡΠΌΠΎΠ΄ΡΡ ΡΠ·Π°ΡΠΈΠ½ΡΠ² Π· 5-Π°ΠΌΡΠ½ΠΎΠΏΡΡΠ°Π·ΠΎΠ»Π°ΠΌΠΈ ΡΠ° 2,2-Π΄ΠΈΠΌΠ΅ΡΠΈΠ»-1,3-Π΄ΡΠΎΠΊΡΠ°Π½-4,6-Π΄ΡΠΎΠ½ΠΎΠΌ Ρ ΡΡΠ·Π½ΠΈΡ
ΡΠΌΠΎΠ²Π°Ρ
.Π Π΅Π·ΡΠ»ΡΡΠ°ΡΠΈ ΡΠ° ΡΡ
ΠΎΠ±Π³ΠΎΠ²ΠΎΡΠ΅Π½Π½Ρ. ΠΠΎΠΌΡΠ½ΠΎ-ΡΠ΅Π°ΠΊΡΡΡ ΡΠ·Π°ΡΠΈΠ½ΡΠ², 5-Π°ΠΌΡΠ½ΠΎΠΏΡΡΠ°Π·ΠΎΠ»ΡΠ² ΡΠ° 2,2-Π΄ΠΈΠΌΠ΅ΡΠΈΠ»-1,3-Π΄ΡΠΎΠΊΡΠ°Π½-4,6-Π΄ΡΠΎΠ½Ρ (ΠΊΠΈΡΠ»ΠΎΡΠΈ ΠΠ΅Π»ΡΠ΄ΡΡΠΌΠ°) Ρ ΡΠΏΠΈΡΡΠΎΠ²ΠΎΠΌΡ ΡΠ΅ΡΠ΅Π΄ΠΎΠ²ΠΈΡΡ Π·Π°Π²Π΅ΡΡΡΡΡΡΡΡ ΡΡΠ²ΠΎΡΠ΅Π½Π½ΡΠΌ ΡΡΠΌΡΡΡ ΠΏΡΡΠ°Π·ΠΎΠ»ΠΎ[3,4-b]ΠΏΡΡΠΈΠ΄ΠΈΠ½-4-ΡΠΏΡΡΠΎΡΠ½Π΄ΠΎΠ»ΡΠ½ΠΎΠ½ΡΠ² ΡΠ° 3-(5-Π°ΠΌΡΠ½ΠΎΠΏΡΡΠ°Π·ΠΎΠ»-3-ΡΠ»)-3-Π³ΡΠ΄ΡΠΎΠΊΡΠΈ-2-ΠΎΠΊΡΡΠ½Π΄ΠΎΠ»ΡΠ½ΡΠ² Π· ΠΏΠ΅ΡΠ΅Π²Π°ΠΆΠ½ΠΈΠΌ Π²ΠΌΡΡΡΠΎΠΌ ΡΠΏΡΡΠΎ-ΡΠΏΠΎΠ»ΡΠΊ. 3-(5-ΠΠΌΡΠ½ΠΎΠΏΡΡΠ°Π·ΠΎΠ»-4-ΡΠ»)-3-Π³ΡΠ΄ΡΠΎΠΊΡΠΈ-2-ΠΎΠΊΡΡΠ½Π΄ΠΎΠ»ΡΠ½ΠΈ Π»ΠΈΡΠ΅ Π² ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΡ ΡΠ΅ΡΡΠΎΡΠΎΠ·ΠΏΠ°Π΄Ρ Π½Π° Π²ΠΈΡ
ΡΠ΄Π½Ρ ΡΠ·Π°ΡΠΈΠ½ ΡΠ° Π°ΠΌΡΠ½ΠΎΠΏΡΡΠ°Π·ΠΎΠ» Ρ ΠΏΡΠΈΡΡΡΠ½ΠΎΡΡΡ ΠΊΠΈΡΠ»ΠΎΡΠΈ ΠΠ΅Π»ΡΠ΄ΡΡΠΌΠ° ΠΌΠΎΠΆΡΡΡ Π΄ΡΠΆΠ΅ ΠΏΠΎΠ²ΡΠ»ΡΠ½ΠΎ Π· Π½ΠΈΠ·ΡΠΊΠΈΠΌΠΈ Π²ΠΈΡ
ΠΎΠ΄Π°ΠΌΠΈ ΠΏΠ΅ΡΠ΅ΡΠ²ΠΎΡΡΠ²Π°ΡΠΈΡΡ Π½Π° ΠΏΡΡΠ°Π·ΠΎΠ»ΠΎ[3,4-b]ΠΏΡΡΠΈΠ΄ΠΈΠ½-4-ΡΠΏΡΡΠΎΡΠ½Π΄ΠΎΠ»ΡΠ½ΠΎΠ½ΠΈ.ΠΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ°Π»ΡΠ½Π° ΡΠ°ΡΡΠΈΠ½Π°. ΠΠΈΠΏβΡΡΡΠ½Π½ΡΠΌ Ρ ΠΌΠ΅ΡΠ°Π½ΠΎΠ»Ρ Π΅ΠΊΠ²ΡΠΌΠΎΠ»ΡΠ½ΠΈΡ
ΠΊΡΠ»ΡΠΊΠΎΡΡΠ΅ΠΉ ΡΠ·Π°ΡΠΈΠ½ΡΠ², 5-Π°ΠΌΡΠ½ΠΎΠΏΡΡΠ°Π·ΠΎΠ»ΡΠ² ΡΠ° ΠΊΠΈΡΠ»ΠΎΡΠΈ ΠΠ΅Π»ΡΠ΄ΡΡΠΌΠ° ΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΎ ΡΡΠΌΡΡΡ ΠΏΡΡΠ°Π·ΠΎΠ»ΠΎ[3,4-b]ΠΏΡΡΠΈΠ΄ΠΈΠ½-4-ΡΠΏΡΡΠΎΡΠ½Π΄ΠΎΠ»ΡΠ½ΠΎΠ½ΡΠ² ΡΠ° 3-(5-Π°ΠΌΡΠ½ΠΎΠΏΡΡΠ°Π·ΠΎΠ»-3-ΡΠ»)-3-Π³ΡΠ΄ΡΠΎΠΊΡΠΈ-2-ΠΎΠΊΡΡΠ½Π΄ΠΎΠ»ΡΠ½ΡΠ², ΡΠΊΡ ΡΠΎΠ·Π΄ΡΠ»Π΅Π½Ρ ΠΊΡΠΈΡΡΠ°Π»ΡΠ·Π°ΡΡΡΡ. ΠΠΈΡ
ΡΠ΄ ΡΠΏΡΡΠΎ-ΡΠΏΠΎΠ»ΡΠΊ ΡΠΊΠ»Π°Π΄Π°Ρ 26-82 %, Π° 3-(5-Π°ΠΌΡΠ½ΠΎΠΏΡΡΠ°Π·ΠΎΠ»-3-ΡΠ»)-3-Π³ΡΠ΄ΡΠΎΠΊΡΠΈ-2-ΠΎΠΊΡΡΠ½Π΄ΠΎΠ»ΡΠ½ΡΠ² β 5-23 %. ΠΠ΅ΡΠ΅ΡΠ²ΠΎΡΠ΅Π½Π½Ρ ΠΎΡΡΠ°Π½Π½ΡΡ
Ρ ΠΏΡΠΈΡΡΡΠ½ΠΎΡΡΡ ΠΊΠΈΡΠ»ΠΎΡΠΈ ΠΠ΅Π»ΡΠ΄ΡΡΠΌΠ° Π½Π° ΡΠΏΡΡΠΎ-ΡΠΏΠΎΠ»ΡΠΊΠΈ Π²ΡΠ΄Π±ΡΠ²Π°ΡΡΡΡΡ ΠΏΡΠΈ ΡΡΠΈΠ²Π°Π»ΠΎΠΌΡ ΠΊΠΈΠΏβΡΡΡΠ½Π½Ρ Ρ ΡΠΏΠΈΡΡΠΎΠ²ΠΎΠΌΡ ΡΠ΅ΡΠ΅Π΄ΠΎΠ²ΠΈΡΡ Ρ ΡΡΠΏΡΠΎΠ²ΠΎΠ΄ΠΆΡΡΡΡΡΡ Π²ΠΊΡΠ°ΠΉ Π½ΠΈΠ·ΡΠΊΠΈΠΌΠΈ Π²ΠΈΡ
ΠΎΠ΄Π°ΠΌΠΈ. Π‘ΡΡΡΠΊΡΡΡΡ Ρ ΡΠΊΠ»Π°Π΄ ΡΡΡΡ
ΡΠΈΠ½ΡΠ΅Π·ΠΎΠ²Π°Π½ΠΈΡ
ΡΠΏΠΎΠ»ΡΠΊ Π΄ΠΎΠ²Π΅Π΄Π΅Π½ΠΎ Π΄Π°Π½ΠΈΠΌΠΈ Π―ΠΠ 1Π, ΠΌΠ°Ρ-ΡΠΏΠ΅ΠΊΡΡΡΠ² Ρ Π΅Π»Π΅ΠΌΠ΅Π½ΡΠ½ΠΈΠΌ Π°Π½Π°Π»ΡΠ·ΠΎΠΌ.ΠΠΈΡΠ½ΠΎΠ²ΠΊΠΈ. ΠΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ΠΎ, ΡΠΎ Ρ ΡΡΠΈΠΊΠΎΠΌΠΏΠΎΠ½Π΅Π½ΡΠ½ΠΈΡ
ΡΠ΅Π°ΠΊΡΡΡΡ
ΡΠ·Π°ΡΠΈΠ½ΡΠ², 5-Π°ΠΌΡΠ½ΠΎΠΏΡΡΠ°Π·ΠΎΠ»ΡΠ² Ρ 2,2-Π΄ΠΈΠΌΠ΅ΡΠΈΠ»-1,3-Π΄ΡΠΎΠΊΡΠ°Π½-4,6-Π΄ΡΠΎΠ½Ρ ΡΠ΅Π°Π»ΡΠ·ΡΡΡΡΡΡ Π΄Π²Π° ΠΊΠΎΠ½ΠΊΡΡΡΡΡΠΈΡ
Π½Π°ΠΏΡΡΠΌΠΊΠΈ Π²Π·Π°ΡΠΌΠΎΠ΄ΡΡ ΡΠ·Π°ΡΠΈΠ½Ρ Π· Π½ΡΠΊΠ»Π΅ΠΎΡΡΠ»Π°ΠΌΠΈ. ΠΠ΄ΠΈΠ½ Π· Π½ΠΈΡ
β Π½ΡΠΊΠ»Π΅ΠΎΡΡΠ»ΡΠ½Π΅ ΠΏΡΠΈΡΠ΄Π½Π°Π½Π½Ρ Π‘4 ΡΠ΅Π°ΠΊΡΡΠΉΠ½ΠΎΠ³ΠΎ ΡΠ΅Π½ΡΡΠ° Π°ΠΌΡΠ½ΠΎΠΏΡΡΠ°Π·ΠΎΠ»Ρ Π΄ΠΎ ΠΊΠ°ΡΠ±ΠΎΠ½ΡΠ»ΡΠ½ΠΎΡ Π³ΡΡΠΏΠΈ ΡΠ·Π°ΡΠΈΠ½Ρ ΠΏΡΠΈΠ²ΠΎΠ΄ΠΈΡΡ Π΄ΠΎ 3-(5-Π°ΠΌΡΠ½ΠΎΠΏΡΡΠ°Π·ΠΎΠ»-4-ΡΠ»)-3-Π³ΡΠ΄ΡΠΎΠΊΡΠΈ-2-ΠΎΠΊΡΡΠ½Π΄ΠΎΠ»ΡΠ½ΡΠ². Π ΡΠ½ΡΠΈΠΉ β ΠΊΠΎΠ½Π΄Π΅Π½ΡΠ°ΡΡΡ ΡΠ·Π°ΡΠΈΠ½Ρ Π· Π΄ΡΠΎΠΊΡΠ°Π½-4,6-Π΄ΡΠΎΠ½ΠΎΠΌ Π·Π° ΠΠ½ΡΠΎΠ²Π΅Π½Π°Π³Π΅Π»Π΅ΠΌ Π·Π°ΠΏΠΎΡΠ°ΡΠΊΠΎΠ²ΡΡ Π΄ΠΎΠΌΡΠ½ΠΎ-ΠΏΡΠΎΡΠ΅Ρ, ΡΠΊΠΈΠΉ Π·Π°Π²Π΅ΡΡΡΡΡΡΡΡ ΡΡΠ²ΠΎΡΠ΅Π½Π½ΡΠΌ ΠΏΠ΅ΡΠ΅Π²Π°ΠΆΠ½ΠΈΡ
ΠΏΡΠΎΠ΄ΡΠΊΡΡΠ² ΡΠ΅Π°ΠΊΡΡΡ β ΠΏΡΡΠ°Π·ΠΎΠ»ΠΎ[3,4-b]ΠΏΡΡΠΈΠ΄ΠΈΠ½-4-ΡΠΏΡΡΠΎΡΠ½Π΄ΠΎΠ»ΡΠ½ΠΎΠ½ΡΠ²
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