329 research outputs found
Uniformly Accelerated Mirrors. Part 2: Quantum Correlations
We study the correlations between the particles emitted by a moving mirror.
To this end, we first analyze , the
two-point function of the stress tensor of the radiation field. In this we
generalize the work undertaken by Carlitz and Willey. To further analyze how
the vacuum correlations on are scattered by the mirror and redistributed
among the produced pairs of particles, we use a more powerful approach based on
the value of which is conditional to the detection of a given
particle on . We apply both methods to the fluxes emitted by a uniformly
accelerated mirror. This case is particularly interesting because of its strong
interferences which lead to a vanishing flux, and because of its divergences
which are due to the infinite blue shift effects associated with the horizons.
Using the conditional value of , we reveal the existence of
correlations between created particles and their partners in a domain where the
mean fluxes and the two-point function vanish. This demonstrates that the
scattering by an accelerated mirror leads to a steady conversion of vacuum
fluctuations into pairs of quanta. Finally, we study the scattering by two
uniformly accelerated mirrors which follow symmetrical trajectories (i.e. which
possess the same horizons). When using the Davies-Fulling model, the Bogoliubov
coefficients encoding pair creation vanish because of perfectly destructive
interferences. When using regularized amplitudes, these interferences are
inevitably lost thereby giving rise to pair creation.Comment: 30 pages, 9 postscript figure
Entanglement Dynamics between Inertial and Non-uniformly Accelerated Detectors
We study the time-dependence of quantum entanglement between two Unruh-DeWitt
detectors, one at rest in a Minkowski frame, the other non-uniformly
accelerated in some specified way. The two detectors each couple to a scalar
quantum field but do not interact directly. The primary challenge in problems
involving non-uniformly accelerated detectors arises from the fact that an
event horizon is absent and the Unruh temperature is ill-defined. By numerical
calculation we demonstrate that the correlators of the accelerated detector in
the weak coupling limit behaves like those of an oscillator in a bath of
time-varying "temperature" proportional to the instantaneous proper
acceleration of the detector, with oscillatory modifications due to
non-adiabatic effects. We find that in this setup the acceleration of the
detector in effect slows down the disentanglement process in Minkowski time due
to the time dilation in that moving detectorComment: 20 pages, 15 figures; References added; More analysis given in
Appendix C; Typos correcte
The challenges of modeling and forecasting the spread of COVID-19
The coronavirus disease 2019 (COVID-19) pandemic has placed epidemic modeling at the forefront of worldwide public policy making. Nonetheless, modeling and forecasting the spread of COVID-19 remains a challenge. Here, we detail three regional-scale models for forecasting and assessing the course of the pandemic. This work demonstrates the utility of parsimonious models for early-time data and provides an accessible framework for generating policy-relevant insights into its course. We show how these models can be connected to each other and to time series data for a particular region. Capable of measuring and forecasting the impacts of social distancing, these models highlight the dangers of relaxing nonpharmaceutical public health interventions in the absence of a vaccine or antiviral therapies
International trade and domestic competition: Evidence from Belgium
We investigate the effect of domestic market competition on firm-level export intensity. We employ a comprehensive dataset of Belgian firms from 2005–2008, when the fall in the number of firms engaged in trade was accompanied by a growing amount of transactions. The resulting increase in the domestic concentration of Belgian firms has sparked numerous debates, since the direction of causality between domestic market structure and export performance is unclear. We apply the fractional logit estimator and control for both self-selection and simultaneity bias. We find that a positive linkage exists between the level of competition and export intensity
Differential impact of malaria control interventions on P. falciparum and P. vivax infections in young Papua New Guinean children
INTRODUCTION: As malaria transmission declines, understanding the differential impact of intensified control on Plasmodium falciparum relative to Plasmodium vivax and identifying key drivers of ongoing transmission is essential to guide future interventions. METHODS: Three longitudinal child cohorts were conducted in Papua New Guinea before (2006/2007), during (2008) and after scale-up of control interventions (2013). In each cohort, children aged 1-5 years were actively monitored for infection and illness. Incidence of malaria episodes, molecular force of blood-stage infections (molFOB) and population-averaged prevalence of infections were compared across the cohorts to investigate the impact of intensified control in young children and the key risk factors for malaria infection and illness in 2013. RESULTS: Between 2006 and 2008, P. falciparum infection prevalence, molFOB, and clinical malaria episodes reduced by 47%, 59% and 69%, respectively, and a further 49%, 29% and 75% from 2008 to 2013 (prevalence 41.6% to 22.1% to 11.2%; molFOB: 3.4 to 1.4 to 1.0 clones/child/year; clinical episodes incidence rate (IR) 2.6 to 0.8 to IR 0.2 episodes/child/year). P. vivax clinical episodes declined at rates comparable to P. falciparum between 2006, 2008 and 2013 (IR 2.5 to 1.1 to 0.2), while P. vivax molFOB (2006, 9.8; 2008, 12.1) and prevalence (2006, 59.6%; 2008, 65.0%) remained high in 2008. However, in 2013, P. vivax molFOB (1.2) and prevalence (19.7%) had also substantially declined. In 2013, 89% of P. falciparum and 93% of P. vivax infections were asymptomatic, 62% and 47%, respectively, were sub-microscopic. Area of residence was the major determinant of malaria infection and illness. CONCLUSION: Intensified vector control and routine case management had a differential impact on rates of P. falciparum and P. vivax infections but not clinical malaria episodes in young children. This suggests comparable reductions in new mosquito-derived infections but a delayed impact on P. vivax relapsing infections due to a previously acquired reservoir of hypnozoites. This demonstrates the need to strengthen implementation of P. vivax radical cure to maximise impact of control in co-endemic areas. The high heterogeneity of malaria in 2013 highlights the importance of surveillance and targeted interventions to accelerate towards elimination
Unruh--DeWitt detectors in spherically symmetric dynamical space-times
In the present paper, Unruh--DeWitt detectors are used in order to
investigate the issue of temperature associated with a spherically symmetric
dynamical space-times. Firstly, we review the semi-classical tunneling method,
then we introduce the Unruh--DeWitt detector approach. We show that for the
generic static black hole case and the FRW de Sitter case, making use of
peculiar Kodama trajectories, semiclassical and quantum field theoretic
techniques give the same standard and well known thermal interpretation, with
an associated temperature, corrected by appropriate Tolman factors. For a FRW
space-time interpolating de Sitter space with the Einstein--de Sitter universe
(that is a more realistic situation in the frame of CDM cosmologies),
we show that the detector response splits into a de Sitter contribution plus a
fluctuating term containing no trace of Boltzmann-like factors, but rather
describing the way thermal equilibrium is reached in the late time limit. As a
consequence, and unlike the case of black holes, the identification of the
dynamical surface gravity of a cosmological trapping horizon as an effective
temperature parameter seems lost, at least for our co-moving simplified
detectors. The possibility remains that a detector performing a proper motion
along a Kodama trajectory may register something more, in which case the
horizon surface gravity would be associated more likely to vacuum correlations
than to particle creation.Comment: 19 pages, to appear on IJTP. arXiv admin note: substantial text
overlap with arXiv:1101.525
Quantitative assessment of airborne exposures generated during common cleaning tasks: a pilot study
Background: A growing body of epidemiologic evidence suggests an association between exposure to cleaning products with asthma and other respiratory disorders. Thus far, these studies have conducted only limited quantitative exposure assessments. Exposures from cleaning products are difficult to measure because they are complex mixtures of chemicals with a range of physicochemical properties, thus requiring multiple measurement techniques. We conducted a pilot exposure assessment study to identify methods for assessing short term, task-based airborne exposures and to quantitatively evaluate airborne exposures associated with cleaning tasks simulated under controlled work environment conditions. Methods: Sink, mirror, and toilet bowl cleaning tasks were simulated in a large ventilated bathroom and a small unventilated bathroom using a general purpose, a glass, and a bathroom cleaner. All tasks were performed for 10 minutes. Airborne total volatile organic compounds (TVOC) generated during the tasks were measured using a direct reading instrument (DRI) with a photo ionization detector. Volatile organic ingredients of the cleaning mixtures were assessed utilizing an integrated sampling and analytic method, EPA TO-17. Ammonia air concentrations were also measured with an electrochemical sensor embedded in the DRI. Results: Average TVOC concentrations calculated for 10 minute tasks ranged 0.02 - 6.49 ppm and the highest peak concentrations observed ranged 0.14-11 ppm. TVOC time concentration profiles indicated that exposures above background level remained present for about 20 minutes after cessation of the tasks. Among several targeted VOC compounds from cleaning mixtures, only 2-BE was detectable with the EPA method. The ten minute average 2- BE concentrations ranged 0.30 -21 ppm between tasks. The DRI underestimated 2-BE exposures compared to the results from the integrated method. The highest concentration of ammonia of 2.8 ppm occurred during mirror cleaning. Conclusions: Our results indicate that airborne exposures from short-term cleaning tasks can remain in the air even after tasks' cessation, suggesting potential exposures to anyone entering the room shortly after cleaning. Additionally, 2-BE concentrations from cleaning could approach occupational exposure limits and warrant further investigation. Measurement methods applied in this study can be useful for workplace assessment of airborne exposures during cleaning, if the limitations identified here are addressed
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A Qualitative Analysis of Experiential Challenges Associated with Meditation Practice
Although empirical interest in meditation has flourished in recent years, few studies have addressed possible downsides of meditation practice, particularly in community populations. In-depth interviews were conducted with 30 male meditators in London, UK, recruited using principles of maximum variation sampling, and analysed using a modified constant comparison approach. Having originally set out simply to inquire about the impact of various meditation practices (including but not limited to mindfulness) on men’s wellbeing, we uncovered psychological challenges associated with its practice. While meditation was generally reported to be conducive to wellbeing, substantial difficulties accounted for approximately one quarter of the interview data. Our paper focuses specifically on these issues in order to alert health professionals to potential challenges associated with meditation. Four main problems of increasing severity were uncovered: Meditation was a difficult skill to learn and practise; participants encountered troubling thoughts and feelings which were hard to manage; meditation reportedly exacerbated mental health issues, such as depression and anxiety; and in a few cases, meditation was associated with psychotic episodes. Our paper raises important issues around safeguarding those who practise meditation, both within therapeutic settings and in the community
Assessing the Combined Public Health Impact of Pharmaceutical Interventions on Pandemic Transmission and Mortality: An Example in SARS CoV-2
To assess the combined role of anti-viral monoclonal antibodies (mAbs) and vaccines in reducing severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) transmission and mortality in the United States, an agent-based model was developed that accounted for social contacts, movement/travel, disease progression, and viral shedding. The model was calibrated to coronavirus disease 2019 (COVID-19) mortality between October 2020 and April 2021 (aggressive pandemic phase), and projected an extended outlook to estimate mortality during a less aggressive phase (April–August 2021). Simulated scenarios evaluated mAbs for averting infections and deaths in addition to vaccines and aggregated non-pharmaceutical interventions. Scenarios included mAbs as a treatment of COVID-19 and for passive immunity for postexposure prophylaxis (PEP) during a period when variants were susceptible to the mAbs. Rapid diagnostic testing paired with mAbs was evaluated as an early treatment-as-prevention strategy. Sensitivity analyses included increasing mAb supply and vaccine rollout. Allocation of mAbs for use only as PEP averted up to 14% more infections than vaccine alone, and targeting individuals ≥ 65 years averted up to 37% more deaths. Rapid testing for earlier diagnosis and mAb use amplified these benefits. Doubling the mAb supply further reduced infections and mortality. mAbs provided benefits even as proportion of the immunized population increased. Model projections estimated that ~ 42% of expected deaths between April and August 2021 could be averted. Assuming sensitivity to mAbs, their use as early treatment and PEP in addition to vaccines would substantially reduce SARS-CoV-2 transmission and mortality even as vaccination increases and mortality decreases. These results provide a template for informing public health policy for future pandemic preparedness
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