Egorov property in perturbed cat map

We study the time evolution of the quantum-classical correspondence (QCC) for the well known model of quantised perturbed cat maps on the torus in the very specific regime of semi-classically small perturbations. The quality of the QCC is measured by the overlap of classical phase-space density and corresponding Wigner function of the quantum system called quantum-classical fidelity (QCF). In the analysed regime the QCF strongly deviates from the known general behaviour in particular it decays faster then exponential. Here we study and explain the observed behavior of the QCF and the apparent violation of the QCC principle.Comment: 12 pages, 7 figure

Folds and Buckles at the Nanoscale: Experimental and Theoretical Investigation of the Bending Properties of Graphene Membranes

The elastic properties of graphene crystals have been extensively investigated, revealing unique properties in the linear and nonlinear regimes, when the membranes are under either stretching or bending loading conditions. Nevertheless less knowledge has been developed so far on folded graphene membranes and ribbons. It has been recently suggested that fold-induced curvatures, without in-plane strain, can affect the local chemical reactivity, the mechanical properties, and the electron transfer in graphene membranes. This intriguing perspective envisages a materials-by-design approach through the engineering of folding and bending to develop enhanced nano-resonators or nano-electro-mechanical devices. Here we present a novel methodology to investigate the mechanical properties of folded and wrinkled graphene crystals, combining transmission electron microscopy mapping of 3D curvatures and theoretical modeling based on continuum elasticity theory and tight-binding atomistic simulations

Therapy discontinuation or substitution in patients with cardiovascular disease, switching among different products of the same off-patent active substance: a 'real-world' retrospective cohort study

OBJECTIVE: The present study investigated the effects of switching to different products of the same off-patent active substance (brand name or generic) on therapy discontinuation or substitution with another molecule of the same class, in patients with cardiovascular disease treated with statins and antihypertensives in a 'real-world' setting. DESIGN: A retrospective cohort study in a 'real-world' setting. SETTING: Analysis of data performed by integrating administrative databases that included approximately two million individuals who are assisted by the National Health System from three Local Health Units located in three different regions of Italy. PARTICIPANTS: All patients aged 6518\u2005years with at least one prescription of simvastatin, ramipril or amlodipine in the period 1 January to 31 December 2010 were included and followed up for 2\u2005years. MAIN OUTCOME MEASURES: Prescription refills occurring during follow-up were evaluated. Frequency of discontinuation of therapy or substitution with another molecule of the same class (eg, from simvastatin to a different statin) during follow-up was identified. RESULTS: During follow-up, therapy discontinuation or substitution was found to be more frequent in patients switching to a different product of the same active substance compared with non-switching patients (11.5% vs 10.8% and 22.2% vs 20.8% (p=0.002), respectively, in the simvastatin group; 4.0% vs 3.5% and 24.6% vs 22.7% (p<0.001), respectively, in the amlodipine group). In the ramipril group, 8% of patients undertook a therapy substitution to another molecule; no trend towards a lower percentage of substitution was observed in the non-switching group, while 18% of patients discontinued treatment, with a significant difference in favour of patients not switching. These findings were partially confirmed by multivariate analysis. CONCLUSIONS: Switches among products of the same active substance are quite common in patients with cardiovascular disease. Our study suggests that switching may expose patients to a higher risk of therapy discontinuation or substitution

Phase separation and pairing regimes in the one-dimensional asymmetric Hubbard model

We address some open questions regarding the phase diagram of the one-dimensional Hubbard model with asymmetric hopping coefficients and balanced species. In the attractive regime we present a numerical study of the passage from on-site pairing dominant correlations at small asymmetries to charge-density waves in the region with markedly different hopping coefficients. In the repulsive regime we exploit two analytical treatments in the strong- and weak-coupling regimes in order to locate the onset of phase separation at small and large asymmetries respectively.Comment: 13 pages, RevTeX 4, 12 eps figures, some additional refs. with respect to v1 and citation errors fixe

Qubit Teleportation and Transfer across Antiferromagnetic Spin Chains

We explore the capability of spin-1/2 chains to act as quantum channels for both teleportation and transfer of qubits. Exploiting the emergence of long-distance entanglement in low-dimensional systems [Phys. Rev. Lett. 96, 247206 (2006)], here we show how to obtain high communication fidelities between distant parties. An investigation of protocols of teleportation and state transfer is presented, in the realistic situation where temperature is included. Basing our setup on antiferromagnetic rotationally invariant systems, both protocols are represented by pure depolarizing channels. We propose a scheme where channel fidelity close to one can be achieved on very long chains at moderately small temperature.Comment: 5 pages, 4 .eps figure

Drug Usage Analysis and Health Care Resources Consumption in Patients With Rheumatoid Arthritis

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Epidemiology of Statin-Treated Patients with Uncontrolled Ldl Levels from Italian Administrative Official Databases

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