443 research outputs found
Cable-stayed glass façades - 15 years of innovation at the cutting edge
Today’s demand for highly transparent building envelopes calls for innovativesolutions. Cable-stayed glass façades make it possible to dematerialize the buildingenvelope so as to make it almost imperceptible. Werner Sobek has designed a greatnumber and variety of cable-stayed façades. The primary structural system carryingmost of these façades consists of straight tension members (e.g. tension rods,cables), typically in a parallel arrangement. The tension members transfer the deadload of the glazing very efficiently to the supports. Under wind load the membersundergo large deflections thus activating their lateral stiffness. As a result, thedetailing of these façades requires innovative design approaches and special care toallow for such large deflections. Besides this, each project has its individualchallenges such as a complex geometry, large openings, difficult edge conditions,warping of IG units, bomb blast requirements, etc. The present article gives anoverview of the development of cable-stayed façades as designed by Werner Sobekover the last 15 years. The overview includes completed projects as well as façadescurrently under construction or in the design phase
Identification of Escherichia coli from broiler chickens in Jordan, their antimicrobial resistance, gene characterization and the associated risk factors
Avian pathogenic Escherichia coli (APEC) is the principle cause of colibacillosis affecting poultry. The main challenge to the poultry industry is antimicrobial resistance and the emergence of multidrug resistant bacteria that threaten the safety of the food chain. Risk factors associated with emergence of antimicrobial resistance among avian pathogenic E. coli were correlated with the inappropriate use of antimicrobials along with inadequate hygienic practices, which encourages the selection pressure of antimicrobial resistant APEC. The aim of this study was to isolate, identify, serogroup and genotype APEC from broilers, assess their antibiotic resistance profile, expressed genes and the associated risk factors
High levels of genetic differentiation and selfing in the Brazilian cerrado fruit tree Dipteryx alata Vog. (Fabaceae).
Neo-LVOT and Transcatheter Mitral Valve Replacement: Expert Recommendations
With the advent of transcatheter mitral valve replacement (TMVR), the concept of the neo-left ventricular outflow tract (LVOT) was introduced and remains an essential component of treatment planning. This paper describes the LVOT anatomy and provides a step-by-step computed tomography methodology to segment and measure the neo-LVOT while discussing the current evidence and outstanding challenges. It also discusses the technical and hemodynamic factors that play a major role in assessing the neo-LVOT. A summary of expert-based recommendations about the overall risk of LVOT obstruction in different scenarios is presented along with the currently available methods to reduce the risk of LVOT obstruction and other post-procedural complications
Effects of asenapine, olanzapine, and risperidone on psychotomimetic-induced reversal-learning deficits in the rat
YesBackground: Asenapine is a new pharmacological agent for the acute treatment of schizophrenia and bipolar disorder. It has relatively higher affinity for serotonergic and α2-adrenergic than dopaminergic D2 receptors. We evaluated the effects of asenapine, risperidone, and olanzapine on acute and subchronic psychotomimetic-induced disruption of cued reversal learning in rats.
Methods: After operant training, rats were treated acutely with D-amphetamine (0.75 mg/kg intraperitoneally [i.p.]) or phencyclidine (PCP; 1.5 mg/kg i.p.) or sub-chronically with PCP (2 mg/kg i.p. for 7 days). We assessed the effects of acute coadministration of asenapine, risperidone, or olanzapine on acute D-amphetamine– and PCP-induced deficits and the effects of long-term coadministration of these agents (for 28 additional days) on the deficits induced by subchronic PCP.
Results: Deficits in reversal learning induced by acute D-amphetamine were attenuated by risperidone (0.2 mg/kg i.p.). Acute PCP-induced impairment of reversal learning was attenuated by acute asenapine (0.025 mg/kg subcutaneously [s.c.]), risperidone (0.2 mg/kg i.p.), and olanzapine (1.0 mg/kg i.p.). Subchronic PCP administration induced an enduring deficit that was attenuated by acute asenapine (0.075 mg/kg s.c.) and by olanzapine (1.5 mg/kg i.p.). Asenapine (0.075 mg/kg s.c.), risperidone (0.2 mg/kg i.p.), and olanzapine (1.0 mg/kg i.p.) all showed sustained efficacy with chronic (29 d) treatment to improve subchronic PCP-induced impairments.
Conclusion: These data suggest that asenapine may have beneficial effects in the treatment of cognitive symptoms in schizophrenia. However, this remains to be validated by further clinical evaluation.This research was supported by Schering-Plough Corporation, now Merck & Co., Inc. and Pfizer Inc
Post-drug consequences of chronic atypical antipsychotic drug administration on the ability to adjust behavior based on feedback in young monkeys
Measurement of the Boson Mass
A measurement of the mass of the boson is presented based on a sample of
5982 decays observed in collisions at
= 1.8~TeV with the D\O\ detector during the 1992--1993 run. From a
fit to the transverse mass spectrum, combined with measurements of the
boson mass, the boson mass is measured to be .Comment: 12 pages, LaTex, style Revtex, including 3 postscript figures
(submitted to PRL
Search for First Generation Scalar Leptoquark Pairs in ppbar Collisions at sqrt(s)=1.8 TeV
We have searched for first generation scalar leptoquark (LQ) pairs in the
enu+jets channel using ppbar collider data (integrated luminosity= 115 pb^-1)
collected by the DZero experiment at the Fermilab Tevatron during 1992-96. The
analysis yields no candidate events. We combine the results with those from the
ee+jets and nunu+jets channels to obtain 95% confidence level (CL) upper limits
on the LQ pair production cross section as a function of mass and of beta, the
branching fraction to a charged lepton. Comparing with the next-to-leading
order theory, we set 95% CL lower limits on the LQ mass of 225, 204, and 79
GeV/c^2 for beta=1, 1/2, and 0, respectively.Comment: 14 pages, 4 figures, submitted to Physical Review Letters Replaced to
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Probing BFKL Dynamics in the Dijet Cross Section at Large Rapidity Intervals in ppbar Collisions at sqrt{s}=1800 and 630 GeV
Inclusive dijet production at large pseudorapidity intervals (delta_eta)
between the two jets has been suggested as a regime for observing BFKL
dynamics. We have measured the dijet cross section for large delta_eta in ppbar
collisions at sqrt{s}=1800 and 630 GeV using the DO detector. The partonic
cross section increases strongly with the size of delta_eta. The observed
growth is even stronger than expected on the basis of BFKL resummation in the
leading logarithmic approximation. The growth of the partonic cross section can
be accommodated with an effective BFKL intercept of
a_{BFKL}(20GeV)=1.65+/-0.07.Comment: Published in Physical Review Letter
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