15,784 research outputs found

    The solar heating and cooling commercial demonstration program: Some early problems and results

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    The activities of the Marshall Space Flight Center of the National Aeronautics and Space Administration in the technical evaluation of proposals, contracts definitions, and program management details are defined and discussed. The significant problems were summarized in both technical and management aspects of the program. It was concluded that the program has significantly stimulated additional solar effort by the program participants. It was also concluded that the use of conventional construction industry organization with design/competitive bid procedures and standards has maintained a cost effective program

    A system for aerodynamic design and analysis of supersonic aircraft. Part 1: General description and theoretical development

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    An integrated system of computer programs was developed for the design and analysis of supersonic configurations. The system uses linearized theory methods for the calculation of surface pressures and supersonic area rule concepts in combination with linearized theory for calculation of aerodynamic force coefficients

    Principles of Life-Death Decision-Making

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    Hydrographic charting from LANDSAT Satellite: A comparison with aircraft imagery

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    The relative capabilities of two remote-sensing systems in measuring depth and, consequently, bottom contours in sandy-bottomed and sediment-laden coastal waters were determined quantitatively. The multispectral scanner (MSS), orbited on the LANDSAT-2 Satellite, and the ocean color scanner (OCS), flown on U-2 aircraft, were used. Analysis of imagery taken simultaneously indicates a potential for hydrographic charting of marine coastal and shallow shelf areas, even when water turbidity is a factor. Several of the eight optical channels examined on the OCS were found to be sensitive to depth or depth-related information. The greatest sensitivity was in OCS-4(0.544 + or - 0.012 microns) from which contours corresponding to depths up to 12m were determined. The sharpness of these contours and their spatial stability through time suggests that upwelling radiance is a measure of bottom reflectance and not of water turbidity. The two visible channels on LANDSAT's MSS were less sensitive in the discrimination of contours, with depths up to 8m in the high-gain mode (3x) determined in MSS-4(0.5 to 0.6 microns)

    Clinically applicable GABA receptor positive allosteric modulators promote ß-cell replication.

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    A key goal of diabetes research is to develop treatments to safely promote human ß-cell replication. It has recently become appreciated that activation of γ-aminobutyric acid receptors (GABA-Rs) on ß-cells can promote their survival and replication. A number of positive allosteric modulators (PAMs) that enhance GABA's actions on neuronal GABAA-Rs are in clinical use. Repurposing these GABAA-R PAMs to help treat diabetes is theoretically appealing because of their safety and potential to enhance the ability of GABA, secreted from ß-cells, or exogenously administered, to promote ß-cell replication and survival. Here, we show that clinically applicable GABAA-R PAMs can increase significantly INS-1 ß-cell replication, which is enhanced by exogenous GABA application. Furthermore, a GABAA-R PAM promoted human islet cell replication in vitro. This effect was abrogated by a GABAA-R antagonist. The combination of a PAM and low levels of exogenous GABA further increased human islet cell replication. These findings suggest that PAMs may potentiate the actions of GABA secreted by islet ß-cells on GABAA-Rs and provide a new class of drugs for diabetes treatment. Finally, our findings may explain a past clinical observation of a GABAA-R PAM reducing HbA1c levels in diabetic patients

    Wind tunnel test results of a new leading edge flap design for highly swept wings, a vortex flap

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    A leading edge flap design for highly swept wings, called a vortex flap, was tested on an arrow wing model in a low speed wind tunnel. A vortex flap differs from a conventional plain flap in that it has a leading edge tab which is counterdeflected from the main portion of the flap. This results in intentional separation at the flap leading edge, causing a vortex to form and lie on the flap. By trapping this vortex, the vortex flap can result in significantly improved wing flow characteristics relative to conventional flaps at moderate to high angles of attack, as demonstrated by the flow visualization results of this tests

    Insulation for cryogenic tanks has reduced thickness and weight

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    Dual seal insulation, consisting of an inner layer of sealed-cell Mylar honeycomb core and an outer helium purge channel of fiber glass reinforced phenolic honeycomb core, is used as a thin, lightweight insulation for external surfaces of cryogenic-propellant tanks

    Modelling of gypsum and ice diapirs in the martian crust

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    Academic Support at Leeds Metropolitan Library

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    Leeds Metropolitan’s Library Academic Support Stream is made up of Academic Librarians and Information Services Librarians who provide academic support to the university’s six faculties. The team use innovative methods of working together to engage students and enhance their experience. The team only formed a year ago so this is a good time to reflect on our success so far. The library service at Leeds Met is continually developing and offers new challenges and opportunities for staff providing library academic support. Innovation has even become part of our new name – ‘Libraries and Learning Innovation’. We still offer all the traditions types of library academic support, but there is an increasing emphasis on finding innovative ways of supporting students and publicising what we can offer. This year the Library Academic Support Stream won a University Attitude Character and Talents Award for Future Focus

    A system for aerodynamic design and analysis of supersonic aircraft. Part 3: Computer program description

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    The computer program documentation for the design and analysis of supersonic configurations is presented. Schematics and block diagrams of the major program structure, together with subroutine descriptions for each module are included
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