Pengembangan Media Pembelajaran Berbasis Moodle Pada Mata Kuliah Fisika Dasar

The purpose of this study was to fundamental develop a Moodle-based learning media and know how to influence the use of instructional media on physics course. This research includes the development of research conducted through three stages that is: preliminary studies, design development, and testing media. Subjects of the study were students at the FPMIPA IKIP Mataram which was following the fundamental Physics course. Moodle-based learning media development in fundamental physics courses have been designed and have done the settings on the story board and page navigation, profile settings, administration settings, and management course settings. Devices and media that have been developed and then validated and tested on a limited scale

Pengaruh Metode Pembelejaran Diskusi Buzzgroup terhadap Keaktifan dan Prestasi Belajar Siswa

This study was conducted to determine the effect of buzz group discussion learning methods on the activeness and learning achievement of physics in class VIII of SMPN 4 Praya Barat Daya 2015/2016 Academic Year. The type of research used in this study is a kind of quasi-experimental research. The population in this study were all eighth-grade students totaling 38 people consisting of class VIII A totaling 20 people as the experimental class and class VIII B totaling 18 people as the control class with the sampling technique used was a saturated sampling technique. The instruments used are valid observation and test sheets both in content, construct, and empirical with a value of 3.34; 3.40; and 3.23, and reliable with the value of αCronbach = 0.608. The results of this study were also able to influence the achievement of learning physics. Based on statistical calculations using the ttest test, the value of tcount = 23.00 is greater than t table = 2.02 (t count = 23.00> t table = 2.02). Thus, it can be concluded that there is the influence of buzz group discussion learning methods on the activeness and learning achievement of physics in class VIII Praya Barat Daya SMP 4 2015/2016 Academic Year

Pengaruh Model Pembelajaran Talking Stick terhadap Keaktifan Belajar Siswa

[Title: The Effect of a Talking Stick Learning Model on Student Learning Activities]. A fun learning environment, active and meaningful for students need to be created by applying active learning model for students that learning model talking stick. This type of research is quasi-experimental. This research aimed to know there is or no effect of talking stick learning model toward students learning activeness. This research implemented in class VIII SMP Negeri 5 Mataram in academic year 2015/2016 from March to April 2016. The technique of sample using cluster random sampling, in order to obtain first-class VIII I totalling 30 students as an experimental class and class VIII E totalling 30 students as the control class. The results of this research are students' activeness learning showed by using the instrument is activeness of student learning questionnaire. Based on data analysis showed that t-test was 8.28 and t- table was 2.000 (df = 58). So, t-test > t-table (8.28 > 2.000). This means that there is an effect of talking stick learning model toward students learning activeness

Bibliometric Evidence for a Hierarchy of the Sciences

The hypothesis of a Hierarchy of the Sciences, first formulated in the 19(th) century, predicts that, moving from simple and general phenomena (e.g. particle dynamics) to complex and particular (e.g. human behaviour), researchers lose ability to reach theoretical and methodological consensus. This hypothesis places each field of research along a continuum of complexity and "softness", with profound implications for our understanding of scientific knowledge. Today, however, the idea is still unproven and philosophically overlooked, too often confused with simplistic dichotomies that contrast natural and social sciences, or science and the humanities. Empirical tests of the hypothesis have usually compared few fields and this, combined with other limitations, makes their results contradictory and inconclusive. We verified whether discipline characteristics reflect a hierarchy, a dichotomy or neither, by sampling nearly 29,000 papers published contemporaneously in 12 disciplines and measuring a set of parameters hypothesised to reflect theoretical and methodological consensus. The biological sciences had in most cases intermediate values between the physical and the social, with bio-molecular disciplines appearing harder than zoology, botany or ecology. In multivariable analyses, most of these parameters were independent predictors of the hierarchy, even when mathematics and the humanities were included. These results support a "gradualist" view of scientific knowledge, suggesting that the Hierarchy of the Sciences provides the best rational framework to understand disciplines' diversity. A deeper grasp of the relationship between subject matter's complexity and consensus could have profound implications for how we interpret, publish, popularize and administer scientific research

Rab11 and Actin Cytoskeleton Participate in Giardia lamblia Encystation, Guiding the Specific Vesicles to the Cyst Wall

The encystation process is crucial for survival and transmission of Giardia lamblia to new hosts. During this process, vesicular trafficking and the cytoskeleton play important roles. In eukaryotic cells, intracellular transport is regulated by proteins, including Rab-GTPases and SNAREs, which regulate vesicle formation along with recognition of and binding to the target membrane. Cytoskeletal structures are also involved in these processes. In this study, we demonstrate the participation of Rab11 in the transport of encystation-specific vesicles (ESVs). Additionally, we demonstrate that disruption of actin microfilaments affects ESVs transport. The modification of actin dynamics was also correlated with a reduction in rab11 and cwp1 expression. Furthermore, down-regulation of rab11 mRNA by a specific hammerhead ribozyme caused nonspecific localization of CWP1. We thus provide new information about the molecular machinery that regulates Giardia lamblia encystation. Given our findings, Rab11 and actin may be useful targets to block Giardia encystation

Participation of Actin on Giardia lamblia Growth and Encystation

BACKGROUND:Microfilaments play a determinant role in different cell processes such as: motility, cell division, phagocytosis and intracellular transport; however, these structures are poorly understood in the parasite Giardia lamblia. METHODOLOGY AND PRINCIPAL FINDINGS:By confocal microscopy using TRITC-phalloidin, we found structured actin distributed in the entire trophozoite, the label stand out at the ventral disc, median body, flagella and around the nuclei. During Giardia encystation, a sequence of morphological changes concurrent to modifications on the distribution of structured actin and in the expression of actin mRNA were observed. To elucidate whether actin participates actively on growth and encystation, cells were treated with Cytochalasin D, Latrunculin A and Jasplakinolide and analyzed by confocal and scanning electron microscopy. All drugs caused a growth reduction (27 to 45%) and changes on the distribution of actin. Besides, 60 to 80% of trophozoites treated with the drugs, exhibited damage at the caudal region, alterations in the flagella and wrinkles-like on the plasma membrane. The drugs also altered the cyst-yield and the morphology, scanning electron microscopy revealed diminished cytokinesis, cysts with damages in the wall and alterations in the size and on the intermembranal space. Furthermore, the drugs caused a significant reduction of the intensity of fluorescence-labeled CWP1 on ESV and on cyst wall, this was coincident with a reduction of CWP1 gene expression (34%). CONCLUSIONS AND SIGNIFICANCE:All our results, indicated an important role of actin in the morphology, growth and encystation and indirectly suggested an actin role in gene expression