Business and IT alignment in companies of Valencian Community in Spain

[EN] In order to create value for the organization, the projects of information technology (IT) need to be in line with the needs of the organization. The management and improvement of this connection is the alignment of business and IT. The aim of this paper is to analyze the degree of alignment in companies of the Valencian community in Spain. The analysis was conducted on a sample of twenty-four companies under the aspects:value IT, communication, IT priority projects and performance, innovation, reliability and IT opportunities in the enterprise. The sectors analyzed were real estate activities, professional and administrative.[ES] Con el fin de generar valor para la organización, los proyectos de tecnología de información (TI) necesitan estar en consonancia con las necesidades de la organización. La gestión y mejora de esta conexión es la alineación de negocio y TI. El objetivo es analizar el grado de alineación en empresas de la Comunidad Valenciana. El análisis se ha llevado a cabo sobre una muestra de veinticuatro empresas bajo los aspectos: valor de TI, comunicación, prioridad de proyectos TI y rendimiento, innovación, fiabilidad y oportunidades de TI en la empresa. Los sectores analizados han sido actividades inmobiliarias, profesionales y administrativas.Esta investigación ha sido llevada a cabo en el marco del proyecto de innovación y mejora (PIME/2013/A/016/B) ‘RECICRE – Rúbrica para la evaluación de la competencia de innovación, creatividad y emprendimiento’. Avalado por la Universitat Politècnica de València y la Escuela Técnica Superior de Ingeniería Informática.Cuenca, L.; Milla, JDD.; Boza García, A. (2015). Análisis de la alineación de las tecnologías de la información y el negocio en empresas de la Comunidad Valenciana. Dirección y Organización. 55:38-43. http://hdl.handle.net/10251/63398S38435

Estudio del proceso de retención de 2,4-D en un carbón activo procedente de cáscara de almendra. II.-Isotermas de retención

Se han estudiado las isotermas de retención de 2,4-D, en disolución acuosa a las temperaturas de 10, 20, 30, 40 Y 50ºC, en un carbón activo preparado a partir de cáscara de almendra. Los datos obtenidos se han ajustado a las ecuaciones de Langmuir, B.E.T. y López-González, las cuales fueron adaptadas adecuadamente a procesos de adsorción en disolución. Se ha calculado la capacidad de retención del carbón activo utilizado, que es del orden de 10-3 moles de 2,4-D por gramo de carbón. Asúnismo, se han determinado la superficie del mismo accesible a las moléculas de 2,4-D, así como las magnitudes termodinámicas aparentes del proceso.Retention isotherms of 2,4-D in aqueous solution on an activated carbon at 10, 20, 30, 40 and 500C have been obtained. The activated carbon was prepared using almond shells as raw material. The retention process has been studied using the Langmuir, B.E.T. and López-González methods, wich were adapted to adsorption from solutions. The retention capacity of this carbon was around 1O-3mols.g-l. The surface area accesible to 2,4-D molecules as well as the thermodynarnic parameters of the process have been also calculated

Estudio del proceso de retención de 2,4-D en un carbón activo procedente de cáscara de almendra. 1.-Cinética del proceso

Se ha estudiado la cinética del proceso de retención de 2,4-D, en disolución acuosa, a las temperaturas de 10, 20, 30, 40 Y 50ºC en un carbón activo preparado a partir de cáscara de almendra. El proceso de retención parece transcurrir mediante un mecanismo reversible de orden dos respecto a la adsorción y de orden uno con respecto a la desorción.The kinetics of the retentiofl process of 2,4-D on one activated carbon from aqueous solution at 10, 20, 30, 40 and 500C has been studied. This carbon was obtained by activation of almond shells. The retention process seems to take place following a reversible mechanism whose order, with respect to the adsorption process is two, and with respect to the desorption process is one

Internalization of the anti-carcinogenic IBB1, a major Bowman-Birk isoinhibitor from soybean (Glycine max), in HT29 colon cancer cells

Proceedings of the I Congress PIIISA celebrado en la Estación Experimental del Zaidín (Granada), en mayo de 2013.Protease inhibitors of the Bowman-Birk type, a major protease inhibitor family in legume seeds, which inhibit potently trypsin- and chymotrypsin-like proteases, are currently being investigated as colorectal chemopreventive agents. Although the therapeutic target/s and the action mechanism/s of Bowman-Birk inhibitors (BBI) have not yet been elucidated, the emerging evidence suggests that BBI exert their chemopreventive properties via protease inhibition; in this sense, serine proteases should be considered as primary targets in early stages of carcinogenesis. In this work, we have demonstrated that IBB1, a major protease inhibitor of the Bowman-Birk family in soybean (Glycine max), exerts anti-proliferative effect in human colorectal HT29 cancer cells at concentrations higher than 15 μM, in a dose dependent manner. By using confocal microscopy, we have demonstrated that IBB1 is taken up by HT29 colon cancer cells in a time-dependent manner, being the bulk of the internalized protease inhibitor localized in the cytoplasm where might interact with their potential therapeutic target/s.This work was supported by ERDF-co-financed grants AGL2011-26353 (Spanish Ministry of Economy and Competitiveness) and PE2010-CVI-5767 (Junta de Andalucía).Peer reviewe

Demonstration of latency-aware 5G network slicing on optical metro networks

The H2020 METRO-HAUL European project has architected a latency-aware, cost-effective, agile, and programmable optical metro network. This includes the design of semi-disaggregated metro nodes with compute and storage capabilities, which interface effectively with both 5G access and multi-Tbit/s elastic optical networks in the core. In this paper, we report the automated deployment of 5G services, in particular, a public safety video surveillance use case employing low-latency object detection and tracking using on-camera and on-the-edge analytics. The demonstration features flexible deployment of network slice instances, implemented in terms of ETSI NFV Network Services. We summarize the key findings in a detailed analysis of end-to-end quality of service, service setup time, and soft-failure detection time. The results show that the round-trip-time over an 80 km link is under 800 µs and the service deployment time under 180 seconds.Horizon 2020 Framework Programme (761727); Bundesministerium für Bildung und Forschung (16KIS0979K).Peer ReviewedArticle signat per 25 autors/es: B. Shariati, Fraunhofer HHI, Berlin, Germany / L. Velasco, Universitat Politècnica de Catalunya, Barcelona, Spain / J.-J. Pedreno-Manresa, ADVA, Munich, Germany / A. Dochhan, ADVA, Munich, Germany / R. Casellas, Centre Tecnològic Telecomunicacions Catalunya, Castelldefels, Spain / A. Muqaddas, University of Bristol, Bristol, UK / O. Gonzalez de Dios, Telefónica, Madrid, Spain / L. Luque Canto, Telefónica, Madrid, Spain / B. Lent, Qognify GmbH, Bruchsal, Germany / J. E. Lopez de Vergara, Naudit HPCN, Madrid, Spain / S. Lopez-Buedo, Naudit HPCN, Madrid, Spain / F. Moreno, Universidad Politécnica de Cartagena, Cartagena, Spain / P. Pavon, Universidad Politécnica de Cartagena, Cartagena, Spain / M. Ruiz, Universitat Politècnica de Catalunya, Barcelona, Spain / S. K. Patri, ADVA, Munich, Germany / A. Giorgetti, CNIT, Pisa, Italy / F. Cugini, CNIT, Pisa, Italy / A. Sgambelluri, CNIT, Pisa, Italy / R. Nejabati, University of Bristol, Bristol, UK / D. Simeonidou, University of Bristol, Bristol, UK / R.-P. Braun, Deutsche Telekom, Germany / A. Autenrieth, ADVA, Munich, Germany / J.-P. Elbers, ADVA, Munich, Germany / J. K. Fischer, Fraunhofer HHI, Berlin, Germany / R. Freund, Fraunhofer HHI, Berlin, GermanyPostprint (author's final draft

Conceptual design of the ITER fast-ion loss detector

A conceptual design of a reciprocating fast-ion loss detector for ITER has been developed and is presented here. Fast-ion orbit simulations in a 3D magnetic equilibrium and up-to-date first wall have been carried out to revise the measurement requirements for the lost alpha monitor in ITER. In agreement with recent observations, the simulations presented here suggest that a pitch-angle resolution of ∼5 ◦ might be necessary to identify the loss mechanisms. Synthetic measurements including realistic lost alpha-particle as well as neutron and gamma fluxes predict scintillator signal-to-noise levels measurable with standard light acquisition systems with the detector aperture at ∼11 cm outside of the diagnostic first wall. At measurement position, heat load on detector head is comparable to that in present devices.Marie Curie FP7 Integration PCIG11-GA2012-321455Ministerio de Economía y Competitividad RYC-2011-09152, FIS2015-69362-P, ENE2012- 3108

Biodegradable FeMnSi sputter-coated macroporous polypropylene membranes for the sustained release of drugs

Pure Fe and FeMnSi thin films were sputtered on macroporous polypropylene (PP) membranes with the aim to obtain biocompatible, biodegradable and, eventually, magnetically-steerable platforms. Room-temperature ferromagnetic response was observed in both Fe- and FeMnSi-coated membranes. Good cell viability was observed in both cases by means of cytotoxicity studies, though the FeMnSi-coated membranes showed higher biodegradability than the Fe-coated ones. Various strategies to functionalize the porous platforms with transferrin-Alexa Fluor 488 (Tf-AF488) molecules were tested to determine an optimal balance between the functionalization yield and the cargo release. The distribution of Tf-AF488 within the FeMnSi-coated PP membranes, as well as its release and uptake by cells, was studied by confocal laser scanning microscopy. A homogeneous distribution of the drug within the membrane skeleton and its sustained release was achieved after three consecutive impregnations followed by the addition of a layer made of gelatin and maltodextrin, which prevented exceedingly fast release. The here-prepared organic-inorganic macroporous membranes could find applications as fixed or magnetically-steerable drug delivery platforms

Queymi N° 23

Revista de difusión cultural, publicada por el INC, filial Ancash, en setiembre de 1983. Cuenta con la colaboración de autores locales y notas informativas sobre la actividad institucional del INC-FA. Contiene: Nota Editorial – Cartas -- Homenaje al libertador Simón Bolívar en el Bicentenario de su nacimiento – Discurso de orden, 21 de julio. Carás, por Francisco Gonzáles -- Discurso de orden, 24 de julio. Plazuela Bolívar de Huarás, por Francisco Gonzáles – Itinerario y cronología de Bolívar en el norte del Perú, por Manuel S. Reyna L. – Bolívar y la amistad, por Sergio Quijada Jara – La última frase de Bolívar – tradición de Ricardo Palma – Actividades del INC-DA – Ancash en la historia. El ambiente revolucionario en Ancash a la llegada de Luzuriaga, por Augusto Alba Herrera – Personajes. Ladislao F. Meza, por Pedro Barrantes – Aurelio Arnao Loli, por Juan de Dios Alba

Peripheral Blood Mononuclear Cells (PBMC) Microbiome is Not Affected by Colon Microbiota in Healthy Goats

BACKGROUND: The knowledge about blood circulating microbiome and its functional relevance in healthy individuals remains limited. An assessment of changes in the circulating microbiome was performed by sequencing peripheral blood mononuclear cells (PBMC) bacterial DNA from goats supplemented or not in early life with rumen liquid transplantation. RESULTS: Most of the bacterial DNA associated to PBMC was identified predominantly as Proteobacteria (55%) followed by Firmicutes (24%), Bacteroidetes (11%) and Actinobacteria (8%). The predominant genera found in PBMC samples were Pseudomonas, Prevotella, Sphingomonas, Acinetobacter, Corynebacterium and Ruminococcus. Other genera such as Butyrivibrivio, Bifidobacterium, Dorea and Coprococcus were also present in lower proportions. Several species known as blood pathogens or others involved in gut homeostasis such as Faecalibacterium prausnitzii were also identified. However, the PBMC microbiome phylum composition differed from that in the colon of goats (P≤0.001), where Firmicutes was the predominant phylum (83%). Although, rumen liquid administration in early-life altered bacterial community structure and increased Tlr5 expression (P=0.020) in colon pointing to higher bacterial translocation, less than 8% of OTUs in colon were also observed in PBMCs. CONCLUSIONS: Data suggest that in physiological conditions, PBMC microbiome differs from and is not affected by colon gut microbiota in small ruminants. Although, further studies with larger number of animals and covering other animal tissues are required, results point to a common circulating bacterial profile on mammals being phylum Proteobacteria, and genera Pseudomonas and Prevotella the most abundants. All suggest that PBMC microbiome in healthy ruminants could be implicated in homeostatic condition. This study expands our knowledge about PBMC microbiome contribution to health in farm animals.This work was supported by grants from the Spanish Ministry of Science and Innovation (MCI) co-financed with FEDER funds [AGL2017-86757- to LA, AGL2017-86938-R to DRY]. Other contributions were SAF2015-65327-R to JA and SAF2015-73549-JIN to HR. LA is a Ramón y Cajal fellow [RYC-2013-13666] from the Spanish Ministry of Science and Innovation. APC is a recipient of a fellowship from the University of the Basque Country. We thank the MCI for the Severo Ochoa Excellence accreditation (SEV-2016-0644) and the Basque Department of Industry, Tourism and Trade (Etortek and Elkartek programs