Weakly nonlinear ion sound waves in gravitational systems

Ion sound waves are studied in a plasma subject to gravitational field. Such systems are interesting by exhibiting a wave growth that is a result of energy flux conservation in inhomogeneous systems. The increasing wave amplitude gives rise to an enhanced interaction between waves and plasma particles that can be modeled by a modified Korteweg-de Vries equation. Analytical results are compared with numerical Particle-in-Cell simulations of the problem. Our code assumes isothermally Boltzmann distributed electrons while the ion component is treated as a collection of individual particles interacting through collective electric fields. Deviations from quasi neutrality are allowed for.Comment: 30 pages, 9 figure

The Impact of Turbulence on the Ionosphere and Magnetosphere

An important property associated with turbulence in plasmas and fluids is anomalous transport. Plasma, being a good conductor, can in addition be affected by turbulence causing an anomalous resistivity that can significantly exceed its classical counterpart. While turbulent transport may be adequately described in configuration space, some aspects of the anomalous resistivity are best accounted for in phase space. Kinetic phenomena like electron and ion phase space vortices can thus act as obstacles for the free flow of slow charged particles. Plasma instabilities and large amplitude plasma waves are candidates for contributions to the anomalous resistivity by generating such structures. Langmuir waves can be relevant, but also others, such as upper- as well as lower-hybrid waves in magnetized plasmas. Often these anomalous resistivity effects can be small, but due to the large spatial and temporal scales involved in space plasmas, planetary ionosphere and magnetosphere in particular, even such moderate effects can be important. This mini-review is discussing elements of the description of plasma turbulence with particular attention to wave phenomena that contribute to anomalous resistivity and diffusion. Turbulence effects can have relevance for space weather phenomena as well, where ground based and airborne activities relying on for instance Global Positioning and Global Navigation Satellite Systems are influenced by plasma conditions in geospace

Inter-individual different responses to continuous and interval training in recreational middle-aged women runners

A crucial subject in sports is identifying the inter-individual variation in response to training, which would allow creating individualised pre-training schedules, improving runner's performance. We aimed to analyse heterogeneity in individual responses to two half-marathon training programmes differing in running volume and intensity in middle-aged recreational women. Twenty women (40±7 years, 61±7kg, 167±6cm, VO2max=48±6 mL·kg-1·min-1) underwent either moderate-intensity continuous (MICT) or high-intensity interval (HIIT) 12-week training. They were evaluated before and after training with maximal incremental tests in the laboratory (VO2max) and in the field (time to exhaustion, TTE; short interval series and long run). All the women participated in the same half-marathon and their finishing times were compared with their previous times. Although the improvements in the mean finishing times were not significant, MICT elicited a greater reduction (3min 50s, P=0.298), with more women (70%) improving on their previous times, than HIIT (reduction of 2min 34s, P=0.197, 50% responders). Laboratory tests showed more differences in the HIIT group (P=0.008), while both groups presented homogeneous significant (P<0.05) increases in TTE. Both in the short interval series and in the long run, HIIT induced better individual improvements, with a greater percentage of responders compared to MICT (100% versus 50% in the short series and 78% versus 38% in the long run). In conclusion, variability in interindividual responses was observed after both MICT and HIIT, with some participants showing improvements (responders) while others did not (non-responders) in different performance parameters, reinforcing the idea that individualised training prescription is needed to optimise performance

Scalar models for the generalized Chaplygin gas and the structure formation constraints

The generalized Chaplygin gas model represents an attempt to unify dark matter and dark energy. It is characterized by a fluid with an equation of state $p = - A/\rho^\alpha$. It can be obtained from a generalization of the DBI action for a scalar, tachyonic field. At background level, this model gives very good results, but it suffers from many drawbacks at perturbative level. We show that, while for background analysis it is possible to consider any value for $\alpha$, the perturbative analysis must be restricted to positive values of $\alpha$. This restriction can be circumvented if the origin of the generalized Chaplygin gas is traced back to a self-interacting scalar field, instead of the DBI action. But, in doing so, the predictions coming from formation of large scale structures reduce the generalized Chaplygin gas model to a kind of quintessence model, and the unification scenario is lost, if the scalar field is the canonical one. However, if the unification condition is imposed from the beginning as a prior, the model may remain competitive. More interesting results, concerning the unification program, are obtained if a non-canonical self-interacting scalar field, inspired by Rastall's theory of gravity, is imposed. In this case, an agreement with the background tests is possible.Comment: Latex file, 25 pages, 33 figures in eps format. New section on scalar models. Accepted for publication in Gravitation&Cosmolog

Gram-negative prosthetic joint infection: outcome of a debridement, antibiotics and implant retention approach. A large multicentre study

AbstractWe aim to evaluate the epidemiology and outcome of gram-negative prosthetic joint infection (GN-PJI) treated with debridement, antibiotics and implant retention (DAIR), identify factors predictive of failure, and determine the impact of ciprofloxacin use on prognosis. We performed a retrospective, multicentre, observational study of GN-PJI diagnosed from 2003 through to 2010 in 16 Spanish hospitals. We define failure as persistence or reappearance of the inflammatory joint signs during follow-up, leading to unplanned surgery or repeat debridement >30 days from the index surgery related death, or suppressive antimicrobial therapy. Parameters predicting failure were analysed with a Cox regression model. A total of 242 patients (33% men; median age 76 years, interquartile range (IQR) 68–81) with 242 episodes of GN-PJI were studied. The implants included 150 (62%) hip, 85 (35%) knee, five (2%) shoulder and two (1%) elbow prostheses. There were 189 (78%) acute infections. Causative microorganisms were Enterobacteriaceae in 78%, Pseudomonas spp. in 20%, and other gram-negative bacilli in 2%. Overall, 19% of isolates were ciprofloxacin resistant. DAIR was used in 174 (72%) cases, with an overall success rate of 68%, which increased to 79% after a median of 25 months' follow-up in ciprofloxacin-susceptible GN-PJIs treated with ciprofloxacin. Ciprofloxacin treatment exhibited an independent protective effect (adjusted hazard ratio (aHR) 0.23; 95% CI, 0.13–0.40; p <0.001), whereas chronic renal impairment predicted failure (aHR, 2.56; 95% CI, 1.14–5.77; p 0.0232). Our results confirm a 79% success rate in ciprofloxacin-susceptible GN-PJI treated with debridement, ciprofloxacin and implant retention. New therapeutic strategies are needed for ciprofloxacin-resistant PJI