1,969 research outputs found
3D printed splint designed by 3D surface scanner for patients with hand allodynia.
Allodynia is a neuropathic pain triggered by a normally painless stimulus: for example, a slight touch on the skin or slight sensation of hot or cold is extremely painful. Rehabilitation is long and uncertain. Protecting the painful area from stimuli is a priority of care. This type of care is complex and challenging for the care team: the pain caused in manufacturing a classic molded orthosis is unbearable for the patient, and the orthosis has a limited lifetime, and experience shows that it is not possible to produce two identical splints. The present study consisted in creating protective splints by 3D printing, designed from data collected with the 3D surface scanner used in our forensic imaging and anthropology unit. The pros and cons of the 3D orthosis versus standard molded orthoses from the point of view of the patient and the practitioner are discussed, with evaluation of related indications of this technology
Sur les arthromyodysplasies chez le veau
Giroud A., Gueguen L. Sur les arthromyodysplasies chez le veau. In: Bulletin de l'Académie Vétérinaire de France tome 126 n°10, 1973. pp. 443-446
2C-B: A New Psychoactive Phenylethylamine Recently Discovered in Ecstasy Tablets Sold on the Swiss Black Market
This study sought to identify, by means of several analytical methods (GC-MS, HPLC-DAD, CE-DAD, FTIR, and NMR), 4-bromo-2,5-dimethoxyphenethylamine (2C-B), which was found in two sets of tablets obtained from the Swiss black market. Unequivocal identification of 2C-B was only achieved by a combination of mass spectrometric and NMR analysis. Quantitation of 2C-B was performed by HPLC-DAD and CE-DAD. The amounts of 2C-B found in the tablets (3-8 mg) were in the range of the minimum quantity required to induce the effects characteristic of this dru
Gyrokinetic analysis and simulation of pedestals, to identify the culprits for energy losses using fingerprints
Fusion performance in tokamaks hinges critically on the efficacy of the Edge
Transport Barrier (ETB) at suppressing energy losses. The new concept of
fingerprints is introduced to identify the instabilities that cause the
transport losses in the ETB of many of today's experiments, from widely posited
candidates. Analysis of the Gyrokinetic-Maxwell equations, and gyrokinetic
simulations of experiments, find that each mode type produces characteristic
ratios of transport in the various channels: density, heat and impurities.
This, together with experimental observations of transport in some channel, or,
of the relative size of the driving sources of channels, can identify or
determine the dominant modes causing energy transport. In multiple ELMy H-mode
cases that are examined, these fingerprints indicate that MHD-like modes are
apparently not the dominant agent of energy transport; rather, this role is
played by Micro-Tearing Modes (MTM) and Electron Temperature Gradient (ETG)
modes, and in addition, possibly Ion Temperature Gradient (ITG)/Trapped
Electron Modes (ITG/TEM) on JET. MHD-like modes may dominate the electron
particle losses. Fluctuation frequency can also be an important means of
identification, and is often closely related to the transport fingerprint. The
analytical arguments unify and explain previously disparate experimental
observations on multiple devices, including DIII-D, JET and ASDEX-U, and
detailed simulations of two DIII-D ETBs also demonstrate and corroborate this
Enhancement of the Josephson current by magnetic field in superconducting tunnel structures with paramagnetic spacer
The dc Josephson critical current of a (S/M)IS tunnel structure in a parallel
magnetic field has been investigated (here S is a superconductor, S/M is the
proximity coupled S and paramagnet M bilayer and I is an insulating barrier).
We consider the case when, due to the Hund's rule, in the M metal the effective
molecular interaction aligns spins of the conducting electrons antiparallel to
localized spins of magnetic ions. It is predicted that for tunnel structures
under consideration there are the conditions when the destructive action of the
internal and the applied magnetic fields on Cooper pairs is weakened and the
increase of the applied magnetic field causes the field-induced enhancement of
the tunnel critical current. The experimental realization of this interesting
effect of the interplay between superconductivity and magnetism is also
discussed.Comment: 5 pages 3 figure
Cellular entry of nanoparticles via serum sensitive clathrin-mediated endocytosis, and plasma membrane permeabilization
Increasing production and application of nanomaterials raises significant questions regarding the potential for cellular entry and toxicity of nanoparticles. It was observed that the presence of serum reduces the cellular association of 20 nm carboxylate-modified fluorescent polystyrene beads up to 20-fold, relative to cells incubated in serum-free media. Analysis by confocal microscopy demonstrated that the presence of serum greatly reduces the cell surface association of nanoparticles, as well as the potential for internalization. However, both in the presence and absence of serum, nanoparticle entry depends upon clathrin-mediated endocytosis. Finally, experiments performed with cells cooled to 4°C suggest that a proportion of the accumulation of nanoparticles in cells was likely due to direct permeabilization of the plasma membrane
A spin triplet supercurrent through the half-metallic ferromagnet CrO2
In general, conventional superconductivity should not occur in a ferromagnet,
though it has been seen in iron under pressure. Moreover, theory predicts that
the current is always carried by pairs of electrons in a spin singlet state, so
conventional superconductivity decays very rapidly when in contact with a
ferromagnet, which normally prohibits the existence of singlet pairs. It has
been predicted that this rapid spatial decay would not occur when spin triplet
superconductivity could be induced in the ferromagnet. Here we report a
Josephson supercurrent through the strong ferromagnet CrO2, from which we infer
that it is a spin triplet supercurrent. Our experimental setup is different
from those envisaged in the earlier predictions, but we conclude that the
underlying physical explanation for our result is a conversion from spin
singlet to spin triplets at the interface. The supercurrent can be switched
with the direction of the magnetization, analogous to spin valve transistors,
and therefore could enable magnetization-controlled Josephson junctions.Comment: 14 pages, including 3 figure
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