139 research outputs found
Mining Data to Catch Tax Cheats
This teaching case covers technical and non-technical concerns about data mining enabled by the creation of a data warehouse by the California Franchise Tax Board (CFTB). CFTB used data mining to analyze data collected from federal, state and municipal agencies and other organizations to identify residents who under-report income or fail to file tax returns. The case presents different stakeholders’ privacy, financial, technical and political concerns regarding the use of data obtained from an array of sources. The case is aimed at an undergraduate or MBA/MS course on IS Management, Data Management/Warehousing or Information Privacy. It could also be used to study IT and public policy, or E-government. It provides an opportunity for students to consider how social and political factors interact with technical challenges in inter-enterprise relationships. It also offers an opportunity to consider the value of data in relation to both the financial and non-financial costs of obtaining it
Assessing Risks in Two Projects: A Strategic Opportunity and a Necessary Evil
McFarlan\u27s IT Project Risk Assessment Framework (Applegate, et al., 1996), identifies three main areas of IT project risk: project size, project structure, and technology familiarity. According to this framework, if two IT projects are of similar size, a project which is designed primarily around emerging technologies will entail significantly higher risks than a project which is designed primarily around traditional technologies. This paper analyzes two comparably-sized IT projects. One - a telemedicine initiative at Fletcher-Allen Health Care in Vermont -- is designed primarily around emerging technologies. The other - the year 2000 compliance program at the New York Metropolitan Transportation Authority (MTA) - is focused primarily on fixing and testing existing systems on traditional platforms. Our assessment identified two additional salient criteria which, when applied to the two projects revealed higher risks at the MTA. These criteria are time constraints (i.e., the immovable deadline of the year 2000) and system interdependence (i.e., the need for applications to share data with other applications, both within the MTA and with numerous external parties). When these two factors are taken into account, it becomes evident that Year 2000 initiatives represent far higher project risks than the emerging technology projects that are considered to be on the bleeding edge
Is There Gold in California Data Mines?: Using Stakeholder Theory to Analyze the Tradeoff Berween Individual Privacy and the Public Good
In the public sector, tradeoffs between individual citizen concerns and the public good can be complex, since individual goals can conflict with the government’s goals for assuring equity and social welfare. This paper reports on a case study of the Integrated Non-Filer Compliance (INC) system used by the California Franchise Tax Board (CFTB). Data gathered from federal, state and municipal agencies and other organizations are analyzed by CFTB to identify citizens who fail to file taxes or under-report income. The paper uses stakeholder theory to analyze the privacy concerns raised by this inter-agency information-sharing initiative due to the potential for inaccurate judgments based on errors in data interpretation. Key stakeholders here include California citizens, the Franchise Tax Board, and other public sector actors, including politicians and various other state and federal agencies. The paper concludes that stakeholder theory can help identify and avoid privacy issues raised in e-government applications
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THE ECOLOGY OF INTERORGANIZATIONAL INFORMATION SHARING
Increasingly, companies use interorganizational information systems to support business process partnerships, such as automatic replenishment systems and other supply chain initiatives, invoicing and payments, and insurance claims processing. Inter-firm networking in turn can increase the visibility of information generated and used by business partners. These business partners may experience intended and unintended impacts from the changes in the partnering relationship, in effect altering the ecology of the organization. Yet IT researchers rarely study an organization’s ecology, focusing instead on impacts upon internal processes. Our goal in this paper is to propose a definition of interorganizational information ecology, to provide IT researchers with a lens through which interorganizational information sharing should be studied. We begin by reviewing principles of ecology from the natural and social sciences and then discuss the emergence of principles of organizational ecology and information ecology within the management literature. We then argue that advances in information technology have been a primary enabler for companies’ focus on interorganizational business processes and that field research on IT-enabled business partnerships must include the impacts upon each partner and the information shared among them. An example from health care demonstrates the usefulness of the concept, and we conclude with suggestions for field-based research on the ecology of interorganizational information sharing
Business Process Modeling for Successful Implementation of Interorganizational Systems
Studies show that the physical implementation of an interorganizational business process or system can be a major source of operational problems and reduced business benefits. Better process modeling has been advocated as a solution. Although powerful modeling tools exist, current practice often gives short-shrift to documenting the physical implementation details that can create or exacerbate such problems. In this paper we describe the modeling approach we devised for the interorganizational business processes and systems we observe in our ongoing fieldwork. Our approach involves using allowable extensions to a popular modeling notation (BPMN), although other modeling tools would work equally well. We illustrate the benefit of our approach in the case of the Internet Payment Platform, a pilot project of the United States Department of the Treasury
I've got toothache, I need antibiotics: a UK perspective on rational antibiotic prescribing by dentists
Antibiotics do not cure toothache. This headline message of the United Kingdom’s (UK) Dental Antimicrobial Stewardship (AMS) toolkit’s posters and leaflets is aimed at patients; clinicians are expected to know this already. Evidence based clinical guidelines exist to set clear standards for good clinical practice yet there are barriers to compliance. The national AMS audit tool is designed for clinicians to review their management of acute dental conditions, including but not limited to the prescription of antibiotics. In this article we aim to help dental teams protect their patients and themselves from adverse events related to antibiotic prescription. It explores the emergent problem of Clostridium difficile, antibiotic resistance and severe sepsis, and considers some of the barriers, which clinicians have suggested, contribute to the unjustified prescription of antibiotics. Dentists must weigh the risks against the benefits before prescribing any antibiotic
Evolutionary Genomics of Genes Involved in Olfactory Behavior in the Drosophila melanogaster Species Group
Previous comparative genomic studies of genes involved in olfactory behavior in Drosophila focused only on particular gene families such as odorant receptor and/or odorant binding proteins. However, olfactory behavior has a complex genetic architecture that is orchestrated by many interacting genes. In this paper, we present a comparative genomic study of olfactory behavior in Drosophila including an extended set of genes known to affect olfactory behavior. We took advantage of the recent burst of whole genome sequences and the development of powerful statistical tools to analyze genomic data and test evolutionary and functional hypotheses of olfactory genes in the six species of the Drosophila melanogaster species group for which whole genome sequences are available. Our study reveals widespread purifying selection and limited incidence of positive selection on olfactory genes. We show that the pace of evolution of olfactory genes is mostly independent of the life cycle stage, and of the number of life cycle stages, in which they participate in olfaction. However, we detected a relationship between evolutionary rates and the position that the gene products occupy in the olfactory system, genes occupying central positions tend to be more constrained than peripheral genes. Finally, we demonstrate that specialization to one host does not seem to be associated with bursts of adaptive evolution in olfactory genes in D. sechellia and D. erecta, the two specialists species analyzed, but rather different lineages have idiosyncratic evolutionary histories in which both historical and ecological factors have been involved
Stepping on invisible land: on the importance of communicating the value of soils.
Soils play fundamental roles in the functioning of the Earth's ecosystems. Despite numerous initiatives to protect soils, it continues to be generally perceived as dirt or, at best, the surface we walk on. To better understand soil perception by the public, we conducted a survey with 99 participants from Poland and Brazil. We applied opportunity sampling and conducted semi-structured interviews with 40 respondents from Poland and 30 from Brazil, and 29 unstructured interviews in Brazil. Most of the respondents (53%) of the semi-structured interviews associated soil with the surface where plants grow, while 27% said that it is the ground we step on. When asked about pro-environmental campaigns, none of the respondents pointed to soil-related initiatives. Most of the respondents (99%) claimed that there is a need to increase their knowledge about the importance of soils, mostly through education (30%). The majority of the respondents of the unstructured interviews in Brazil indicated provision services provided by soils and pointed to the need for youth engagement in soil communication, corroborating the results from the semi-structured interviews. To address this, we present the results on artistic workshops as an experimental model for teaching and dissemination. We present two short documentary movies reporting the results from unstructured interviews and artistic workshops that can be used as data gathering tools, teaching tools and for dissemination purposes. This is a novel approach to communicating with the relevant stakeholders to promote more sustainable resource management
Inhibition of platelet aggregation by carbon monoxide-releasing molecules (CO-RMs): comparison with NO donors
Carbon monoxide (CO) and CO-releasing molecules (CO-RMs) inhibit platelet aggregation in vitro. Herein, we compare the anti-platelet action of CORM-3, which releases CO rapidly (t½ 1 min), and CORM-A1, which slowly releases CO (t½ = 21 min). The anti-platelet effects of NO donors with various kinetics of NO release were studied for comparison. The effects of CO-RMs and NO donors were analyzed in washed human platelets (WP), platelets rich plasma (PRP), or whole blood (WB) using aggregometry technique. CORM-3 and CORM-A1 inhibited platelet aggregation in human PRP, WP, or WB, in a concentration-dependent manner. In all three preparations, CORM-A1 was more potent than CORM-3. Inhibition of platelets aggregation by CORM-A1 was not significantly affected by a guanylate cyclase inhibitor (ODQ) and a phosphodiesterase-5 inhibitor, sildenafil. In contrast, inhibition of platelet aggregation by NO donors was more potent with a fast NO releaser (DEA-NO, t½ = 2 min) than slow NO releasers such as PAPA-NO (t½ = 15 min) or other slow NO donors. Predictably, the anti-platelet effect of DEA-NO and other NO donors was reversed by ODQ while potentiated by sildenafil. In contrast to NO donors which inhibit platelets proportionally to the kinetics of NO released via activation of soluble guanylate cyclase (sGC), the slow CO-releaser CORM-A1 is a superior anti-platelet agent as compared to CORM-3 which releases CO instantly. The anti-platelet action of CO-RMs does not involve sGC activation. Importantly, CORM-A1 or its derivatives representing the class of slow CO releasers display promising pharmacological profile as anti-platelet agents
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