1,141 research outputs found
Tracking system study
A digital computer program was generated which mathematically describes an optimal estimator-controller technique as applied to the control of antenna tracking systems used by NASA. Simulation studies utilizing this program were conducted using the IBM 360/91 computer. The basic ideas of applying optimal estimator-controller techniques to antenna tracking systems are discussed. A survey of existing tracking methods is given along with shortcomings and inherent errors. It is explained how these errors can be considerably reduced if optimal estimation and control are used. The modified programs generated in this project are described and the simulation results are summarized. The new algorithms for direct synthesis and stabilization of the systems including nonlinearities, are presented
Fast-ignition design transport studies: realistic electron source, integrated PIC-hydrodynamics, imposed magnetic fields
Transport modeling of idealized, cone-guided fast ignition targets indicates
the severe challenge posed by fast-electron source divergence. The hybrid
particle-in-cell [PIC] code Zuma is run in tandem with the
radiation-hydrodynamics code Hydra to model fast-electron propagation, fuel
heating, and thermonuclear burn. The fast electron source is based on a 3D
explicit-PIC laser-plasma simulation with the PSC code. This shows a quasi
two-temperature energy spectrum, and a divergent angle spectrum (average
velocity-space polar angle of 52 degrees). Transport simulations with the
PIC-based divergence do not ignite for > 1 MJ of fast-electron energy, for a
modest 70 micron standoff distance from fast-electron injection to the dense
fuel. However, artificially collimating the source gives an ignition energy of
132 kJ. To mitigate the divergence, we consider imposed axial magnetic fields.
Uniform fields ~50 MG are sufficient to recover the artificially collimated
ignition energy. Experiments at the Omega laser facility have generated fields
of this magnitude by imploding a capsule in seed fields of 50-100 kG. Such
imploded fields are however more compressed in the transport region than in the
laser absorption region. When fast electrons encounter increasing field
strength, magnetic mirroring can reflect a substantial fraction of them and
reduce coupling to the fuel. A hollow magnetic pipe, which peaks at a finite
radius, is presented as one field configuration which circumvents mirroring.Comment: 16 pages, 17 figures, submitted to Phys. Plasma
Influence of home and school environments on specific dietary behaviors among postpartum, high-risk teens, 27 states, 2007-2009
INTRODUCTION: The objective of this study was to determine whether perceptions of the home and school food environments are related to food and beverage intakes of postpartum teens. METHODS: Our study was a baseline, cross-sectional analysis of 853 postpartum teens enrolled in a weight-loss intervention study across 27 states from 2007 through 2009. Eight-item scales assessed perceived accessibility and availability of foods and beverages in school and home environments. Associations between environments and intakes were assessed by using χ(2) and using logistic regression with generalized estimating equations (GEE), respectively. RESULTS: Overall, 52% of teens perceived their school food environment as positive, and 68% of teens perceived their home food environment as positive. A positive school environment was independently associated with fruit consumption and 100% fruit juice consumption. A positive home environment was independently associated with fruit, vegetable, and water consumption and infrequent consumption of soda and chips (χ(2) P < .05). Having only a positive school environment was associated with fruit consumption (GEE odds ratio [OR], 3.1; 95% confidence interval [CI], 1.5–6.5), and having only a positive home environment was associated with fruit (GEE OR, 2.9; 95% CI, 1.6–5.6), vegetable (GEE OR, 3.1; 95% CI, 1.5–6.2), and water (GEE OR, 2.6; 95% CI, 1.7–4.0) consumption and infrequent consumption of soda (GEE OR, 0.5; 95% CI, 0.3–0.7). Results for positive home and school environments were similar to those for positive home only. CONCLUSION: Home and school environments are related to dietary behaviors among postpartum teens, with a positive home environment more strongly associated with healthful behaviors
Impact of Type 2 diabetes prevention programmes based on risk identification and lifestyle intervention intensity strategies: a cost-effectiveness analysis
Aim
To develop a cost-effectiveness model to compare Type 2 diabetes prevention programmes that target different at-risk population subgroups through lifestyle interventions of varying intensity.
Methods
An individual patient simulation model simulated the development of diabetes in a representative sample of adults without diabetes from the UK population. The model incorporates trajectories for HbA1c, 2-h glucose, fasting plasma glucose, BMI, systolic blood pressure, total cholesterol and HDL cholesterol. In the model, patients can be diagnosed with diabetes, cardiovascular disease, microvascular complications of diabetes, cancer, osteoarthritis and depression, or can die. The model collects costs and utilities over a lifetime horizon. The perspective is the UK National Health Service and Personal Social Services. We used the model to evaluate the population-wide impact of targeting a lifestyle intervention of varying intensity to six population subgroups defined as at high risk for diabetes.
Results
The intervention produces 0.0020 to 0.0026 incremental quality-adjusted life-years and saves £15 to £23 per person in the general population, depending on the subgroup targeted. Cost-effectiveness increases with intervention intensity. The most cost-effective options were to target South-Asian people and those with HbA1c levels > 42 mmol/mol (6%).
Conclusion
The model indicates that diabetes prevention interventions are likely to be cost-saving. The criteria for selecting at-risk individuals differentially has an impact on diabetes and cardiovascular disease outcomes, and on the timing of costs and benefits. The model is not currently able to account for potential differential uptake or efficacy between subgroups. These findings have implications for deciding who should be targeted for diabetes prevention interventions.NIH
SPHR Diabetes Prevention Model: Detailed Description of Model Background, Methods, Assumptions and Parameters
Type-2 diabetes is a complex disease with multiple risk factors and health consequences whose prevention is a major public health priority. We have developed a microsimulation model written in the R programming language that can evaluate the effectiveness and cost-effectiveness of a comprehensive range of different diabetes prevention interventions, either in the general population or in subgroups at high risk of diabetes. Within the model individual patients with different risk factors for diabetes follow metabolic trajectories (for body mass index, cholesterol, systolic blood pressure and glycaemia), develop diabetes, complications of diabetes and related disorders including cardiovascular disease and cancer, and eventually die. Lifetime costs and quality-adjusted life-years are collected for each patient. The model allows assessment of the wider social impact on employment and the equity impact of different interventions. Interventions may be population-based, community-based or individually targeted, and administered singly or layered together. The model is fully enabled for probabilistic sensitivity analysis (PSA) to provide an estimate of decision uncertainty. This discussion paper provides a detailed description of the model background, methods and assumptions, together with details of all parameters used in the model, their sources and distributions for PSA
Energy spectra of the ocean's internal wave field: theory and observations
The high-frequency limit of the Garrett and Munk spectrum of internal waves
in the ocean and the observed deviations from it are shown to form a pattern
consistent with the predictions of wave turbulence theory. In particular, the
high frequency limit of the Garrett and Munk spectrum constitutes an {\it
exact} steady state solution of the corresponding kinetic equation.Comment: 4 pages, one color figur
Multi-filament structures in relativistic self-focusing
A simple model is derived to prove the multi-filament structure of
relativistic self-focusing with ultra-intense lasers. Exact analytical
solutions describing the transverse structure of waveguide channels with
electron cavitation, for which both the relativistic and ponderomotive
nonlinearities are taken into account, are presented.Comment: 21 pages, 12 figures, submitted to Physical Review
Electromagnetic energy penetration in the self-induced transparency regime of relativistic laser-plasma interactions
Two scenarios for the penetration of relativistically intense laser radiation
into an overdense plasma, accessible by self-induced transparency, are
presented. For supercritical densities less than 1.5 times the critical one,
penetration of laser energy occurs by soliton-like structures moving into the
plasma. At higher background densities laser light penetrates over a finite
length only, that increases with the incident intensity. In this regime
plasma-field structures represent alternating electron layers separated by
about half a wavelength by depleted regions.Comment: 9 pages, 4 figures, submitted for publication to PR
Cone-Guided Fast Ignition with no Imposed Magnetic Fields
Simulations of ignition-scale fast ignition targets have been performed with
the new integrated Zuma-Hydra PIC-hydrodynamic capability. We consider an
idealized spherical DT fuel assembly with a carbon cone, and an
artificially-collimated fast electron source. We study the role of E and B
fields and the fast electron energy spectrum. For mono-energetic 1.5 MeV fast
electrons, without E and B fields, the energy needed for ignition is E_f^{ig} =
30 kJ. This is about 3.5x the minimal deposited ignition energy of 8.7 kJ for
our fuel density of 450 g/cm^3. Including E and B fields with the resistive
Ohm's law E = \eta J_b gives E_f^{ig} = 20 kJ, while using the full Ohm's law
gives E_f^{ig} > 40 kJ. This is due to magnetic self-guiding in the former
case, and \nabla n \times \nabla T magnetic fields in the latter. Using a
realistic, quasi two-temperature energy spectrum derived from PIC laser-plasma
simulations increases E_f^{ig} to (102, 81, 162) kJ for (no E/B, E = \eta J_b,
full Ohm's law). This stems from the electrons being too energetic to fully
stop in the optimal hot spot depth.Comment: Minor revisions in response to referee comment
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