6 research outputs found

    Modelización numérica bidimensional y tridimensional aplicado al mecanizado de aleaciones aeronáuticas

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    In order to analyzing industrial machining processes, it is proposed to develop two-dimensional and three-dimensional machining models on materials of great industrial interest and aeronautical interest in particular, specifically Ti-6Al-4V and Inconel®718 respectively. In this case, it is proposed, on the one hand, three two-dimensional orthogonal cutting models: based on fracture energies, multipass model and model with implementation of cohesive elements. On the other hand, the development of a general non-orthogonal three-dimensional based on shear failure is proposed. The results of these models will be analyzed on: cutting forces, chip morphology, thermal evolution on the tool and, in the case of the three-dimensional model, local variables such as deformations, strain rate and temperatures. The behavior of both materials will be defined under the Johnson-Cook constitutive equation with their respective parameters and in all cases the models will be validated from experimental tests from several authorsCon el objetivo de analizar procesos de mecanizado industriales se propone desarrollar modelos de mecanizado bidimensionales y tridimensional sobre materiales de gran interés industrial y aeronáutico en particular, concretamente Ti-6Al-4V e Inconel®718 respectivamente. En este sentido se propone, por un lado, tres modelos bidimensionales de corte ortogonal: basado en energías de fractura, modelo multipasada y modelo con implementación de elementos cohesivos. Por otro lado se propone el desarrollo de un modelo tridimensional de corte no ortogonal general basado en fallo por deformación a cortadura. Se analizarán los resultados de dichos modelos sobre: fuerzas de corte, morfología de viruta, evolución térmica sobre la herramienta y, en el caso del modelo tridimensional, variables locales como deformaciones, velocidades de deformación y temperaturas. El comportamiento de ambos materiales se definirán bajo la ecuación constitutiva de Johnson-Cook con sus respectivos parámetros y en todos los casos los modelos se validarán a partir de ensayos experimentales de diversos autores.Programa de Doctorado en Ingeniería Mecánica y de Organización Industrial por la Universidad Carlos III de MadridPresidente: Carlos Santiuste Romero.- Secretario: Roberto D'Amato.- Vocal: José Porras Galá

    Análisis numérico del efecto de la protección de mandíbula y visor del casco de combate bajo cargas explosivas

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    En este trabajo se ha analizado numéricamente, mediante el uso del código comercial de elementos finitos ABAQUS/Explicit, el comportamiento de distintos componentes de una protección personal de cabeza humana (casco de combate) ante una amenaza explosiva. Los resultados obtenidos muestran la propagación de la onda de choque, responsable del incremento de la presión intracraneal. El desarrollo óptimo de la protección personal de la cabeza permite paliar el efecto de la onda presión sin exceder los límites establecidos.Los autores quieren agradecer la financiación recibida del Ministerio de Economía y Competitividad a través de los Proyectos RTC-2015-3887-8 y DPI2011-23191 en el Programa Estatal de Investigación, Desarrollo e Innovación Orientada a los Retos de la Sociedad, en el marco del Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016

    Contemporary use of cefazolin for MSSA infective endocarditis: analysis of a national prospective cohort

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    Objectives: This study aimed to assess the real use of cefazolin for methicillin-susceptible Staphylococcus aureus (MSSA) infective endocarditis (IE) in the Spanish National Endocarditis Database (GAMES) and to compare it with antistaphylococcal penicillin (ASP). Methods: Prospective cohort study with retrospective analysis of a cohort of MSSA IE treated with cloxacillin and/or cefazolin. Outcomes assessed were relapse; intra-hospital, overall, and endocarditis-related mortality; and adverse events. Risk of renal toxicity with each treatment was evaluated separately. Results: We included 631 IE episodes caused by MSSA treated with cloxacillin and/or cefazolin. Antibiotic treatment was cloxacillin, cefazolin, or both in 537 (85%), 57 (9%), and 37 (6%) episodes, respectively. Patients treated with cefazolin had significantly higher rates of comorbidities (median Charlson Index 7, P <0.01) and previous renal failure (57.9%, P <0.01). Patients treated with cloxacillin presented higher rates of septic shock (25%, P = 0.033) and new-onset or worsening renal failure (47.3%, P = 0.024) with significantly higher rates of in-hospital mortality (38.5%, P = 0.017). One-year IE-related mortality and rate of relapses were similar between treatment groups. None of the treatments were identified as risk or protective factors. Conclusion: Our results suggest that cefazolin is a valuable option for the treatment of MSSA IE, without differences in 1-year mortality or relapses compared with cloxacillin, and might be considered equally effective

    Long-term effect of a practice-based intervention (HAPPY AUDIT) aimed at reducing antibiotic prescribing in patients with respiratory tract infections

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    Mural Endocarditis: The GAMES Registry Series and Review of the Literature

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    Characteristics and predictors of death among 4035 consecutively hospitalized patients with COVID-19 in Spain

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