25 research outputs found
Homogeneous bilayer graphene film based flexible transparent conductor
Graphene is considered a promising candidate to replace conventional
transparent conductors due to its low opacity, high carrier mobility and
flexible structure. Multi-layer graphene or stacked single layer graphenes have
been investigated in the past but both have their drawbacks. The uniformity of
multi-layer graphene is still questionable, and single layer graphene stacks
require many transfer processes to achieve sufficiently low sheet resistance.
In this work, bilayer graphene film grown with low pressure chemical vapor
deposition was used as a transparent conductor for the first time. The
technique was demonstrated to be highly efficient in fabricating a conductive
and uniform transparent conductor compared to multi-layer or single layer
graphene. Four transfers of bilayer graphene yielded a transparent conducting
film with a sheet resistance of 180 {\Omega}_{\square} at a transmittance of
83%. In addition, bilayer graphene films transferred onto plastic substrate
showed remarkable robustness against bending, with sheet resistance change less
than 15% at 2.14% strain, a 20-fold improvement over commercial indium oxide
films.Comment: Published in Nanoscale, Nov. 2011 : http://www.rsc.org/nanoscal
Open Pore Ultrafiltration Hollow Fiber Membrane Fabrication Method via Dual Pore Former with Dual Dope Solution Phase
Hollow-fiber membranes are widely used in various fields of membrane processes because of their numerous properties, e.g., large surface area, high packing density, mass production with uniform quality, obvious end-of-life indicators, and so on. However, it is difficult to control the pores and internal properties of hollow-fiber membranes due to their inherent structure: a hollow inside surrounded by a wall membrane. Herein, we aimed to control pores and the internal structure of hollow-fiber membranes by fabricating a dual layer using a dual nozzle. Two different pore formers, polyethylene glycol (PEG) and polyvinyl pyrrolidone (PVP), were separately prepared in the dope solutions and used for spinning the dual layer. Our results show that nanoscale pores could be formed on the lumen side (26.8–33.2 nm), and the open pores continuously increased in size toward the shell side. Due to robust pore structure, our fabricated membrane exhibited a remarkable water permeability of 296.2 ± 5.7 L/m2·h·bar and an extremely low BSA loss rate of 0.06 ± 0.02%, i.e., a high BSA retention of 99.94%. In consideration of these properties, the studied membranes are well-suited for use in either water treatment or hemodialysis. Overall, our membranes could be considered for the latter application with a high urea clearance of 257.6 mL/min, which is comparable with commercial membranes
Reconstruction of Partially Broken Vascular Structures in X-Ray Images via Vesselness-Loss-Based Multi-Scale Generative Adversarial Networks
Coronary artery procedures are primarily performed based on X-ray angiography images. However, coronary arteries in X-ray images are often partially broken, complicating diagnoses and procedures owing to lack of visibility. In this paper, we propose a fully automatic method to restore locally broken parts of coronary arteries in X-ray images without using any external information, such as computed tomography images. To this end, we design a new multi-scale generative adversarial network and a vesselness-loss function. The proposed method is optimized for focus on elongated structures and can be utilized in various clinical applications. The proposed method is evaluated and compared with four other existing methods using the performance metrics, PSNR, MSE, and SSIM, and the result shows 34.3, 0.18, and 0.91 averages, respectively for each metric. Based on the performance result, the blocked regions are plausibly reconstructed into such original shapes of blood vessels, which can aid in image-based guiding catheter manipulation during coronary artery procedures. Eventually, the proposed method can be utilized in various clinical applications, e.g., image-based planning and guidance of coronary procedures and prior simulation of results
Evidence for Extraction of Photoexcited Hot Carriers from Graphene
We report evidence of nonequilibrium hot carrier extraction from graphene by gate-dependent photocurrent study. Scanning photocurrent excited by femtosecond pulse laser shows unusual gate dependence compared with continuous wave (CW) laser excitation. Power dependence studies further confirm that the photocarriers extracted at the metal/graphene contact are nonequilibrium hot carriers. Hot carrier extraction is found to be most efficient near the Dirac point where carrier lifetime reaches a maximum. These observations not only provide evidence of hot carrier extraction from graphene but also open the door for graphene-based hot carrier optoelectronics
Antioxidative properties of ginsenoside Ro against UV-B-induced oxidative stress in human dermal fibroblasts
<p>Ginsenoside Ro (Ro), an oleanolic acid-type ginsenoside, exhibited suppressive activities on reactive oxygen species (ROS) and matrix metalloproteinase-2 (MMP-2) elevation in UV-B-irradiated fibroblasts. Ro could overcome the reduction of the total glutathione (GSH) contents in UV-B-irradiated fibroblasts. Ro could not interfere with cell viabilities in UV-B-irradiated fibroblasts. Collectively, Ro possesses a potential skin anti-photoaging property against UV-B radiation in fibroblasts.</p
High prevalence of increased sitosterol levels in hypercholesterolemic children suggest underestimation of sitosterolemia incidence.
BackgroundSitosterolemia is an inherited lipid disorder which presents with elevated serum sitosterol and can result in an increased risk of premature cardiovascular disease. However, sitosterol cannot be accurately measured by routine diagnostic assays, meaning that sitosterolemia diagnosis can often be difficult, especially with many clinical features overlapping with familial hypercholesterolemia. With such complications resulting in increasing reports of misdiagnosis, the prevalence of sitosterolemia is predicted to be much higher than previously reported.MethodsGas chromatography-mass spectrometry was utilized to measure sitosterol levels of normocholesterolemic and hypercholesterolemic children. Subsequently, an epidemiologically determined cutoff level of sitosterol was calculated and applied to estimate the prevalence of children with increased sitosterol and identify potential sitosterolemia patients. Massively parallel sequencing was used to confirm the diagnosis in suspected patients.ResultsSamples from 109 normocholesterolemic and 220 hypercholesterolemic were tested for phytosterols. Sitosterol and campesterol levels were significantly increased in hypercholesterolemic children (mean 22.0±45.9 μmol/L for sitosterol and 26.0±32.8 μmol/L for campesterol) compared to normocholesterolemic children (mean 12.1±4.9 μmol/L for sistosterol and 14.8±6.7 μmol/L for campesterol). Via application of a cutoff of 35.9 μmol/L, the prevalence rates for increased and overtly increased sitosterol in hypercholesterolemic children were 6.4% and 1.4% respectively. Furthermore, 3 suspected sitosterolemia patients were identified, with 2 patients receiving molecular confirmation for sitosterolemia diagnosis.ConclusionsOur findings reaffirm that the prevalence of sitosterolemia is probably much higher than previously reported, which also indicates the significant risk of misdiagnosis of sitosterolemia with familial hypercholesterolemia. Special lipid testing including sitosterol, especially in children with uncontrolled hypercholesterolemia, is recommended in children in order to identify potential sitosterolemia patients that would otherwise be neglected
A novel semi-analytical approach for solving nonlinear Volterra integro-differential equations
In this work, we present an efficient semi-analytical method based on the Taylor series for solving nonlinear Volterra integro-differential equations, namely the differential transform method (DTM). The DTM provides a recursive relation for the coefficients of the Taylor series that is derived from the given equations. We provide a new recursive relation for the nonlinear Volterra integro-differential equations with complex nonlinear kernels. Since the DTM is based on the Taylor series, it is difficult to obtain accurate approximate solutions in a large domain. To overcome this difficulty, the standard DTM is applied in each subdomain, called the multistage differential transform method (MsDTM). We also present an convergence analysis for the proposed method. To demonstrate the efficiency of the proposed method, several numerical examples are performed and support the results in our analysis. (C) 2015 Elsevier Inc. All rights reservedclose0