5,684 research outputs found

    Morpho-functional basis of endothelial dysfunction in diabetes mellitus

    Get PDF
    The diabetes mellitus (DM) inevitably progresses and leads to complications, among which the main place is occupied by micro- and macroangiopathies. The presence of endothelial damage in DM can be established even before macroscopically significant damage to the vessel. At the same time, there is no summary ED characteristic for diabetes. The aim of the study is to make a comprehensive evaluation of ED in DM -1 and DM-2 types.Materials and methods of research. 60 persons, including 53 DM type 1 and type 2, with a severe course (state of decompensation) participated in the present study. We used the method of estimating ED by the number of circulating desquamation endothelial cells (CECs) at the stages of decomposition with simultaneous determination of NO2- and NO3- metabolites of nitric oxide.Results and discussion. In patients with diabetes, the level of CECs increased in 3-5 times and ranged from 1800 to 11,200 cells / ml. The average amount of CECs in patients with diabetes was 3358.5 ± 366.3 cells / ml.Conclusions: Endothelium is involved in the pathological process at DM. This is evidenced by a significant increase in CECs in the blood plasma. The use of this method allows to detect ED before clinically considerable vascular impairment and reflects the severity of the course and duration of DM

    Optical studies of the X-ray transient XTE J2123-058 -I. Photometry

    Get PDF
    We present optical photometry of the X-ray transient XTE J2123-058, obtained in July-October 1998. The light curves are strongly modulated on the 5.95hrs orbital period, and exhibit dramatic changes in amplitude and form during the decline. We used synthetic models which include the effect of partial eclipses and X-ray heating effects, to estimate the system parameters, and we constrain the binary inclination to be i=73+-4 degrees. The model is successful in reproducing the light curves at different stages of the decay by requiring the accretion disc to become smaller and thinner by 30% as the system fades by 1.7 mags in the optical. From Aug 26 the system reaches quiescence with a mean magnitude of R=21.7+-0.1 and our data are consistent with the optical variability being dominated by the companion's ellipsoidal modulation.Comment: 6 pages, 6 figure

    Pairing state in multicomponent superconductors

    Full text link
    We use the microscopic weak coupling theory to predict the pairing state in superconductors of cubic, hexagonal, or tetragonal symmetry, where the order parameter is multicomponent, i.e., transforms according to either a 2-dimensional or a 3-dimensional representation of the crystal point group. We show that the superconducting phase usually breaks the time-reversal symmetry for singlet multicomponent superconductors. The superconducting order parameter for triplet superconductors in most cases turns out to be non-magnetic.Comment: 7 page

    Resonant photoemission spectroscopy of Cu(InGa)Se2 materials for solar cells

    Full text link
    The electron structure of CuIn1 - x Ga x Se 2 single crystals is determined via resonant photoemis-sion and the main regularities of its transformation upon varying concentration x from 0 to 1 are established. The dependence of the shape of valence band spectra on the photon energy is studied. Integral photoemission intensities are shown to be determined by atomic photoionization cross sections. Processes of the direct and two-step creation of photoelectrons accompanying photoemission and the participation of internal states in the spectra of electrons from valence bands are studied. Two-hole final states in photoemission are obtained upon threshold excitation of the Cu 2p level. The strong interaction of holes leads to the multiplet splitting of these states. Partial densities of the components' states are determined using the energy dependence of atomic photoionization cross sections. © 2013 Allerton Press, Inc
    corecore