Risk of HIV transmission through condomless sex in serodifferent gay couples with the HIV-positive partner taking suppressive antiretroviral therapy (PARTNER): final results of a multicentre, prospective, observational study.

Peer reviewe

Active SLAM using Connectivity Graphs as Priors

Mobile robots can be considered completely autonomous if they embed active algorithms for Simultaneous Localization And Mapping (SLAM). This means that the robot is able to autonomously, or actively, explore and create a reliable map of the environment, while simultaneously estimating its pose. In this paper, we propose a novel framework to robustly solve the active SLAM problem, in scenarios in which some prior information about the environment is available in the form of a topo-metric graph. This information is typically available or can be easily developed in industrial environments, but it is usually affected by uncertainties. In particular, the distinguishing features of our approach are: the inclusion of prior information for solving the active SLAM problem; the exploitation of this information to pursue active loop closure; the on-line correction of the inconsistencies in the provided data. We present some experiments, that are performed in different simulated environments: the results suggest that our method improves on state-of-the-art approaches, as it is able to deal with a wide variety of possibly large uncertainties

Ethics, motivation and rainforest tourguide business interest

Whilst many commentators would hold that an entrepreneurial disposition is a key ingredient in the success of any new business venture in commercial arenas such as tourism, relatively little is known regarding the personal characteristics that may be brought to such a context. This study has sought to examine relationships among ethical values and work motivation as they may predict entrepreneurial interest in a rainforest tour guiding business among a sample of secondary college graduates from a major Australian tourism community. The most prominent value was found to be sociability; diligence was also highly rated, whereas honesty was found to be less so. The most favoured entrepreneurial response involved a cautious interest in this business venture. Major motivating predictors for all three ethical dimensions were social/physical working conditions, individual achievement and personal growth. It was also found that high levels of assent to the diligence ethic were associated with a tourguiding business interest; the honesty ethic was also found to be associated with this expression of entrepreneurialism, though to a lesser degree. Finally, an examination of the relationships between the levels of entrepreneurial interest revealed three groups of respondents: the first group were those likely to declare no interest at all in such a business, who would then generally proceed on to express no interest in the higher levels of entrepreneurial commitment; the second group were those not well disposed to the no interest response, who were found also to favour entrepreneurialism at both the cautious level and the committed level; and finally identified were those respondents who would express some doubt or reluctance with regard to each of the two entrepreneurial interest associations explored. The implications of these findings for future research directions and for industry intervention are examined

An integrated dielectrophoretic chip for continuous bioparticle filtering, focusing, sorting, trapping, and detecting

Multi-target pathogen detection using heterogeneous medical samples require continuous filtering, sorting, and trapping of debris, bioparticles, and immunocolloids within a diagnostic chip. We present an integrated AC dielectrophoretic (DEP) microfluidic platform based on planar electrodes that form three-dimensional (3D) DEP gates. This platform can continuously perform these tasks with a throughput of 3 μL∕min. Mixtures of latex particles, Escherichia coli Nissle, Lactobacillus, and Candida albicans are sorted and concentrated by these 3D DEP gates. Surface enhanced Raman scattering is used as an on-chip detection method on the concentrated bacteria. A processing rate of 500 bacteria was estimated when 100 μl of a heterogeneous colony of 107 colony forming units ∕ml was processed in a single pass within 30 min