Impact of Using Different Stocking Rates of Goats Under Pine Plantation on Plant Species Occurrence and Animal Productivity

Abstract The study assessed the impact of using different stocking rates of goats under pine plantation on plant species occurrence and animal productivity. It was conducted on an 11 year-old loblolly pine plantation site in Epes, Alabama from July to October 2011. Thirty-six Kiko crossbred male goat kids of 4 to 5 months of age were assigned to different stocking rates, namely, low (4 goats/acre), medium (8 goats/acre), and high (12 goats/acre) with three replications each. Forage composition, animal daily gain (ADG) and blood urea nitrogen (BUN) were monitored. Bahia grass (Paspalum notatum) was the most dominant grass species across all treatments. Quantities of understory plant species decreased across all stocking densities with season, but there were no statistical differences (p \u3e 0.05); ADG and BUN were similar. Long-term studies need to be conducted before any meaningful inferences can be drawn. Keywords: Silvopasture, Loblolly Pine, Goats, Understory Species Compositio

Evaluating the Impact of Nitrogen Fertilization Treatments and Irrigation on Soil Health Indicators in a Long-Term Crop Rotation Research Plot

Abstract Many agriculturalists have been focusing on the most efficient farming method that would produce the maximum yield while still sustaining the soil ecosystem. Soil samples were collected from the “Old Rotation” area (Auburn University, Auburn, AL), and were assessed for soil biochemical, chemical and biological characteristics related to soil quality. Treatments of the experimental site were a control with no legumes or N fertilizer; cotton every year with winter legumes; a 3-yr cotton-corn-soybean rotation with wheat and winter legumes; and cotton every year with N fertilizer. Impacts of irrigation were also tested between the sites. Assays were performed measuring phosphomonoesterase and phosphodiesterase activity, soil organic carbon, soil pH, and microbial diversity. The 3-year and winter legume rotations showed significant differences in the structure and membership of microbial communities and differences in biochemical activity. These results further demonstrate the ability of crop rotation to enhance the soil health of agricultural ecosystems. Keywords: Nitrogen Fertilization, Irrigation, Crop Rotation, Soil Ecology, Enzymatic Activit

Fatty Acid Composition of Growing Kiko X Spanish Crossbred Intact Male Goats Fed Varying Levels of Peanut Skins

Abstract The objective was to evaluate the effects of feeding peanut skins (PS) on fatty acid profile of goat meat. The diets used contained 0, 10, 20, and 30% of PS. After 92 days, longissimus muscle (LM), mesenteric adipose (MA), and subcutaneous (SA) tissue samples were analyzed for fatty acid profile. Eighteen (18), 21, and 21 fatty acids were detected in LM, MS and SC adipose tissues, respectively. No changes were detected in the fatty acid profile, but C18:0 increased linearly in LM (p \u3c 0.05) with increasing level of PS whereas C18:1 decreased in the similar manner (p = 0.05). Total saturated fatty acid and monounsaturated fatty acid percentage increased linearly (p \u3c 0.05) in LM fat, but polyunsaturated fatty acids were not different (p \u3e 0.05) among treatments. The results showed that the fatty acid composition of goat carcass can be altered with the dietary addition of PS. Keywords: Meat Goats, Peanut Skins, Fatty Acid

SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway

Vaccines based on the spike protein of SARS-CoV-2 are a cornerstone of the public health response to COVID-19. The emergence of hypermutated, increasingly transmissible variants of concern (VOCs) threaten this strategy. Omicron (B.1.1.529), the fifth VOC to be described, harbours multiple amino acid mutations in spike, half of which lie within the receptor-binding domain. Here we demonstrate substantial evasion of neutralization by Omicron BA.1 and BA.2 variants in vitro using sera from individuals vaccinated with ChAdOx1, BNT162b2 and mRNA-1273. These data were mirrored by a substantial reduction in real-world vaccine effectiveness that was partially restored by booster vaccination. The Omicron variants BA.1 and BA.2 did not induce cell syncytia in vitro and favoured a TMPRSS2-independent endosomal entry pathway, these phenotypes mapping to distinct regions of the spike protein. Impaired cell fusion was determined by the receptor-binding domain, while endosomal entry mapped to the S2 domain. Such marked changes in antigenicity and replicative biology may underlie the rapid global spread and altered pathogenicity of the Omicron variant

Investigation of hospital discharge cases and SARS-CoV-2 introduction into Lothian care homes

Background The first epidemic wave of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in Scotland resulted in high case numbers and mortality in care homes. In Lothian, over one-third of care homes reported an outbreak, while there was limited testing of hospital patients discharged to care homes. Aim To investigate patients discharged from hospitals as a source of SARS-CoV-2 introduction into care homes during the first epidemic wave. Methods A clinical review was performed for all patients discharges from hospitals to care homes from 1st March 2020 to 31st May 2020. Episodes were ruled out based on coronavirus disease 2019 (COVID-19) test history, clinical assessment at discharge, whole-genome sequencing (WGS) data and an infectious period of 14 days. Clinical samples were processed for WGS, and consensus genomes generated were used for analysis using Cluster Investigation and Virus Epidemiological Tool software. Patient timelines were obtained using electronic hospital records. Findings In total, 787 patients discharged from hospitals to care homes were identified. Of these, 776 (99%) were ruled out for subsequent introduction of SARS-CoV-2 into care homes. However, for 10 episodes, the results were inconclusive as there was low genomic diversity in consensus genomes or no sequencing data were available. Only one discharge episode had a genomic, time and location link to positive cases during hospital admission, leading to 10 positive cases in their care home. Conclusion The majority of patients discharged from hospitals were ruled out for introduction of SARS-CoV-2 into care homes, highlighting the importance of screening all new admissions when faced with a novel emerging virus and no available vaccine

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

The original version of this article unfortunately contained a mistake

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

IMPACT OF USING DIFFERENT STOCKING RATES OF GOATS UNDER PINE PLANTATION ON PLANT SPECIES OCCURRENCE AND ANIMAL PRODUCTIVITY

The study assessed the impact of using different stocking rates of goats under pine plantation on plant species occurrence and animal productivity. It was conducted on an 11 year-old loblolly pine plantation site in Epes, Alabama from July to October 2011. Thirty-six Kiko crossbred male goat kids of 4 to 5 months of age were assigned to different stocking rates, namely, low (4 goats/acre), medium (8 goats/acre), and high (12 goats/acre) with three replications each. Forage composition, animal daily gain (ADG) and blood urea nitrogen (BUN) were monitored. Bahia grass (Paspalum notatum) was the most dominant grass species across all treatments. Quantities of understory plant species decreased across all stocking densities with season, but there were no statistical differences (p > 0.05); ADG and BUN were similar. Long-term studies need to be conducted before any meaningful inferences can be drawn