Genetic variability studies in segregating generation for grain and nutritional quality traits in rice (Oryza sativa L.)

The experimental materials used were four traditional landraces and six improved high yielding varieties of Tamil Nadu raised in during kharif 2012-2014. Genetic variability parameters on F3 population (20 selected F3 plants) of two cross combination viz., IR 72 x Veeradangan and ADT 39 x Kavuni in F3 population depicted wide range of variability and its ranged from 6.46 to 10.39 mg/100 g while it was from 5.39 to 7.65 mg/100 g in IR 72 x Veeradangan F3 population. Calcium content for IR 72 x Veeradangan in selected F3 population recorded wide range of variability and its ranged from 61.43 to 97.63 mg/100 g with a mean value of 80.67 mg/100 g whereas, ADT 39 x Kavuni in F3 population revealed the low range of variability and its ranged from 53.38 to 94.25 mg/100 g with a mean value of 79.58 mg/100 g for magnesium content. For iron content, IR 72 x Veeradangan in F3 population showed wide range of variability and its ranged from 0.53 to 1.03 mg/100 g with a grand mean of 0.80 mg/100 g whereas, ADT 39 x Kavuni in F3 population ranged from 0.61 to 1.33 mg/100 g and from with a grand mean value of 0.97 mg/100 g. For zinc content, wide range of variability was found in ADT 39 x Kavuni (1.43 to 2.16 mg/100 g) and in IR 72 x Veeradangan (1.51 to 1.98 mg/100 g) in F3 population

Nutritional and grain quality characters correlation with yield components in different conventional land races and improved varieties for in situ conservation in Tamil Nadu in rice (Oryza sativa L.)

53-60The aim of present research was to assess physicochemical and grain qualities of traditional land races and rice cultivars native to temperate region (Tamil Nadu) of India. Traditional varieties in India and across the Asia serious threat of extension because of arrival of high yielding varieties, hybrids, genetically engineered rice came for nowadays to increase the malnutrition and different human disease is the major problem. Trial material comprised of ten parents which comprised in six cultivars of female parents and four conventional landraces utilized as male parents, F1, F2 and F3 generation of six crosses. Parents and two crosses viz., IR 72 x Veeradangan, ADT 39 x Kavuni were chosen F3 generation dependent on the biometrical characters present in quality and nutritional traits in grains. These desirable characteristics (nutritional, grain quality) exploit farmers to preserve these traditional and improved cultivars encourage farmers to cultivate

Nutritional and grain quality characters correlation with yield components in different conventional land races and improved varieties for in situ conservation in Tamil Nadu in rice (Oryza sativa L.)

The aim of present research was to assess physicochemical and grain qualities of traditional land races and rice cultivars native to temperate region (Tamil Nadu) of India. Traditional varieties in India and across the Asia serious threat of extension because of arrival of high yielding varieties, hybrids, genetically engineered rice came for nowadays to increase the malnutrition and different human disease is the major problem. Trial material comprised of ten parents which comprised in six cultivars of female parents and four conventional landraces utilized as male parents, F1, F2 and F3 generation of six crosses. Parents and two crosses viz., IR 72 x Veeradangan, ADT 39 x Kavuni were chosen F3 generation dependent on the biometrical characters present in quality and nutritional traits in grains. These desirable characteristics (nutritional, grain quality) exploit farmers to preserve these traditional and improved cultivars encourage farmers to cultivate

Effect of Growth hormones for direct organogenesis in Bael (Aegle marmelos (L.) corr)

Aegle marmelos (L.) corr. commonly known as ‘Bael’ tree is included in the red- listed medicinal tree in South India. Riped and unripe fruits, root, bark and leaves of the tree are used in ayurvedic preparation for various ailments. This study was conducted to standardize the media for multiple shoot induction from different explants under in vitro condition. Among the various explants viz., meristematic tip, nodal bud, tender leaf, auxillary bud and cotyledon tried in different media, auxiliary bud had shown good response for shoot induction in 36 to 39 days. Among the various treatments viz., WPM supplemented with Benzyl Amino Purine (BAP) (0.5 to 3.0mg/lit), Kinetin (KN) (0.5 to 3mg/lit) and Indole acetic acid (IAA) (0.5 to 2mg/lit) for multiple shoot induction, the treatmental combination of WPM supplemented with BAP, KN and IAA, @ of each 0.5 mg/lit resulted in 7.75 shoots per cotyledon. The same combination, ½ strength of the medium with 1mg/lit BAP+2mg/lit NAA+ 1% AC resulted in root formation. Hence, as a means of in vitro conservation using cotyledon as explants microproagation is possible in bael

An audit of extra-uterine pregnancy in a tertiary care facility in Northern India

Background: Ectopic pregnancy is the most frequent lethal gynaecological predicament, befalling worldwide in all strata of reproductive women. It remains the leading cause of pregnancy-related first trimester deaths. Though prompt diagnosis has furthered a decline in associated morbidity, an upsurge has been seen in its prevalence owing to a rise in predisposing risk factors. The objectives of this study were to identify incidence, risk factors, and outcome in patients presenting with ectopic pregnancy in a tertiary care hospital.Methods: This two-year retrospective study was conducted in Department of Obstetrics and Gynecology in Vardhaman Mahavir Medical College and Safdarjung hospital, on patients presenting with a diagnosis of ectopic pregnancy (either ruptured or un-ruptured). The primary outcome was incidence of ectopic pregnancy. Secondary outcomes noted were demographic characteristics, predisposing risk factors, clinical presentation and management course in hospital. Data was recorded on a predesigned proforma and deciphered later.Results: Incidence of ectopic pregnancy was 0.82%. Significant causative factors were previous history of PID (29.28%), TB (21.4%), previous pelvic surgeries (18.57%) and preceding ectopic pregnancy (12.14%).Conclusions: Increase awareness and knowledge of risk factors amenable to modification and features will aid early diagnosis of extra-uterine pregnancy, besides planning conservative treatment if possible, and devising effective risk-reduction strategies

Analgesic efficacy of intravenous paracetamol versus intravenous tramadol after caesarean section: a single blind randomized controlled study

Background: Caesarean section is one of the commonest surgeries performed in obstetrics. Adequate management of postoperative pain leads to early mobilization and proper newborn care. The purpose of this study was to compare the analgesic efficacy and side effect profile of Paracetamol versus Tramadol in women undergoing caesarian section.Methods: A single-blind randomized controlled interventional study was conducted in Department of Obstetrics and Gynecology, Vardhman Mahavir Medical College and Safdarjang Hospital, New Delhi over a period of six months from May 2015 to Oct 2015. 100 women undergoing caesarean section under spinal anaesthesia were divided in two groups (50 in each group) using computer generated randomization. One group received Intravenous Paracetamol 1000 mg and another group Intravenous Tramadol 50 mg. The drugs were given 8 hourly for 24 hours. The primary outcome measures were the degree of pain relief during the entire observation period by doing visual analogue scale (VAS) scoring and need of rescue analgesia if any (administered if the VAS score >6); secondary outcome measures were side effects on mother and baby.Results: The pain scores were low in both groups across various time interval except at 6 hours in Paracetamol group (p=0.673) and at 8 hours in Tramadol group (p=0.194). Requirement for rescue analgesia was comparable in both the groups (16% vs. 10%, p = 0.372). However maternal side effects were more in Tramadol group (8% vs. 34%, p = 0.001).Conclusions: Both Paracetamol and Tramadol achieve satisfactory pain control after caesarean section but Tramadol causes significant side effects in mother compared to paracetamol

Maternal anaemia and its severity: an independent risk factor for preterm delivery and adverse neonatal outcome

Background: This study was done to evaluate the effect of maternal anaemia and its severity on gestational age and neonatal outcome.Methods: This was a retrospective study, conducted in Vardhman Mahavir medical college and Safdarjang hospital, New Delhi between April 2012 to March 2013. Cases were divided in three groups i.e. non anaemic, mild to moderately anaemic and severely anaemic (according to WHO classification). A total of 1050 woman (350 in each group) were recruited for study. The following outcome measures were used: preterm delivery (<37 weeks), birth weight, APGAR score, admission of baby in neonatal intensive care unit and early neonatal death. Data was analyzed by Chi-square test. A P value of or less than 0.05 was considered as significant.Results: The risk of preterm delivery, low birth weight, poor APGAR score and admission of baby in neonatal intensive care unit was more in anaemic group and it increased with severity of anaemia which was statistically significant. The increase in risk of early neonatal death was not significant in mild/moderate anaemic group (P value 0.326) while it was statistically significant in severely anaemic group (P value 0.004).Conclusions: Anaemia in pregnancy has a recognizable association with prematurity, low birth weight and poor neonatal outcome.

Comparative evaluation of postpartum versus post MTP insertion of intrauterine contraceptive device

Background: This study was planned to evaluate acceptability, safety and continuation rate of postpartum intrauterine contraceptive device (PPIUCD) and to compare it with well accepted post MTP IUCD in Indian population.Methods: This was a prospective study conducted in VMMC and Safdarjang Hospital, New Delhi, India. Copper T 380-A was inserted in 100 woman in postpartum period and in 100 woman in post MTP period. Follow up done at 6 weeks, 3 months and 6 months. Safety was assessed in terms of expulsion, IUCD failure/pregnancy rate, perforation, removal of IUCD, visibility of strings and various complain at each visit. Continuation rate along with their level of satisfaction was compared at the end of 6 months. SPSS software, Chi-square test and student T test were used for analyzing the results. P value ≤0.05 considered as significant.Results: Acceptance of post MTP IUCD was more than PPIUCD. There was statistically no significant difference in expulsion rate, removal of IUCD and various complaints. There was no case of perforation in either group. Non visibility of strings was major cause of concern and apprehension in PPIUCD group. Only one case of pregnancy was reported in PPIUCD group while no failure was reported in post MTP group. Continuation rate and level of satisfaction were comparable in both groups.Conclusions: PPIUCD is equally safe and effective as post MTP IUCD.

Clinical utility of Shabda and Sparsha Pareeksha in evaluation of Prakruta and Vaikruta Garbhavastha

Garbha is a conglomeration of biological mass with different strata including consciousness, needs an innovative clinical tool to evaluate its well being, which proves safe, potent, cost-effective and noninvasive. The idea of taking up this study was to sensitively predict the Prakrutavastha or well being w.r.t Garbha-pushti and ongoing Fetal Pathology, Vaikrutavastha w.s.r Garbhavyapads for a sharp interference to get a possible best neonatal outcome. The objective of this study was to calculate the predictive accuracy of evaluation of Garbhaspandanam on external Shabda and Sparsha Pareeksha. A Prospective Clinical study of Garbhaspandanam (FHS and FM) with external Shabda and Sparsha stimulation on maternal abdomen, from 24th week onwards was conducted in a cohort of 30 Singleton Pregnant women at Dept. of Prasuti Tantra &amp; Stri Roga, S.D.M.C.A. Hospital, Udupi. Among the 9 cases in abnormal category, 2 cases had gone for IUD and one case though placed in abnormal category had responded relatively well to Shabda and Sparsha Pareeksha which may be due to the proper antenatal care and intervention given along with the patient’s Vatakara Nidana Parivarjana. Predictive Accuracy Rate on Shabda and Sparsha Pareeksha showed, FHS 70%, FM 76.7%; FHS 73.3%, FM 66.7% respectively. Shabda and Sparshapareeksha can be utilized as the Garbha - chetana - dyodakalakshana and can be performed as a routine antenatal bedside procedure, which can fairly detect the Prakruta and Vaikrutavastha of Garbha w.r.t Pushti. However larger prospective studies are required

Carbamazepine-induced Stevens Johnson syndrome: a case series of three case reports

Carbamazepine is an iminostilbene derivative that was initially used as an antiepileptic but has been used with increased frequency for different indications including chronic pain, trigeminal neuralgia, and herpetic neuralgias. This has resulted in increased incidence of carbamazepine related adverse effects such as nausea, vomiting, and serious hematological toxicities such as aplastic anemia, agranulocytosis, eosinophilia, lymphadenopathy, and splenomegaly. Life-threatening hypersensitivity reactions such as Steven Johnson syndrome (SJS) and toxic epidermal necrolysis can also occur. We hereby present a series of three cases that were prescribed carbamazepine for different indications and presented with SJS