Development of an Energy Efficient Stern Flap for Improved EEDI of a Typical High speed Displacement Vessel

The surge in maritime trade is leading to large scale deployment of high-speed displacement ships by all nations. Cargo vessels are designed for a voyage in pre-determined routes at consistent speeds. On the other hand, high-speed displacement vessel engines designed with a capability to cater for top speeds are under-utilised during their normal course of operation. This sub-optimal utilisation impacts efficiency and increases emissions. In this study, a most favourable stern flap is designed for reducing the energy efficiency design index of a typical high-speed displacement vessel with a slender hull. CFD simulations and experimental model testing were conducted for 12 different stern flap configurations for determining most favourable flap design in the Froude no of 0.17-0.48. Performance of the most favourable stern flap was established by calculating, energy efficiency design index (EEDI) and fuel consumption based on typical operating profile. NOx, VOC and PM emissions were estimated in with and without flap condition. Studies demonstrated that the stern flap reduced effective power demand, average fuel consumption and emissions by about 8 per cent, which when considered for the ship’s operating life cycle, are significant. The most favourable stern flap reduced EEDI by 3.74 units and 1.98 units as compared to the bare hull condition and the required EEDI respectively, thereby demonstrating that EEDI could be used as an index to indicate stern flap efficiency

APHRODISIAC ACTIVITY OF CYCAS CIRCINALIS.L AND IONIDIUM SUFFRUTICOSUM.GING ON MALE WISTER ALBINO RATS

Introduction: Cycas circinalis .L and Ionidium suffruticosum. Ging are the two herbs used in Siddha system of medicine (Indian Medicine) for years together to improve the fertility of male. Objective: The aphrodisiac activities of the two herbs Cycas circinalis .L and Ionidium suffruticosum. Ging were tested on male albino rats and compared the effect with normal and positive control male albino rats. Materials and Methods: The present study involves 4 groups, each group has 6 healthy sexually active male albino rats. The Cycas circinalis and Ionidium suffruticosum extract (200mg/kg body weight) were administered orally to 2 experimental group of albino rats and its sexual performance was compared to the normal albino rats (given normal saline) and positive control albino rats (given Sildenafil citrate 4.5mg/kg body weight). The aphrodisiac activities of rats due to the effect of the herb were observed by various parameters such as mount frequency, mount latency, intromission frequency, intromission latency, ejaculation latency, post ejaculatory Interval and total sexual behavior. The data's were analyzed using one way ANOVA and found to be statistically significant. Results: The herbs showed significant positive results in improving various parameters involved in maintaining maleness. The study proves that Cycas circinalis and Ionidium suffruticosum both have aphrodisiac activity and Ionidium suffruticosum was proved to be more effective and almost has the similar effect of Sildenafil citrate. Conclusion The herbal extracts possessing aphrodisiac activity will be of great use for males suffering from sexual disorders like impotence. KEYWORDS: Ionidium suffruticosum, Cycas circinalis, Aphrodisiac activity, Mount frequency, Mount latency, Intromission frequency, Intromission latency, Ejaculation latency, Post ejaculatory interval, Total sexual behavior

Efficient Handwritten Digit Classification using User-defined Classification Algorithm

In automatic numeral digit recognition system, feature selection is most important factor for achieving high recognition performance. To achieve this, the present paper proposed system for isolated handwritten numeral recognition using number of contours, skeleton features, Number of watersheds, and ratio between the numbers of foreground pixels in upper half part and lower half-part of the numerical digit image. Based on these features the present paper designed user-defined classification algorithm for handwritten digit recognition. To find the effectiveness of the proposed features, these features are given as an input for standard classification algorithms like k–nearest neighbor classifier, Support Vector Machines and other classification algorithms and evaluate the results.  The experimental result proves that the proposed features are well suited for handwritten digit recognition for both user and standard classification algorithms. The novelty of the proposed method is size invariant

Topological Indices Polynomials of Domination David Derived Networks

ترتبط الخصائص الكيميائية للمركبات الكيميائية وبنيتها الجزيئية ارتباطًا وثيقًا.  المؤشرات الطوبولوجية هي قيم عددية مرتبطة بالرسوم البيانية الجزيئية الكيميائية التي تساعد في فهم الخصائص الفيزيائية والكيميائية والتفاعل الكيميائي والنشاط البيولوجي للمركب الكيميائي. يتطرق هذا البحث على بعض الخصائص الطوبولوجية للشبكات المشتقة من  dominating David derived وتحصي العديد من K Banhatti  متعدد الحدود من النوع الثاني والثالث من DDD.The chemical properties of chemical compounds and their molecular structures are intimately connected. Topological indices are numerical values associated with chemical molecular graphs that help in understanding the physicochemical properties, chemical reactivity and biological activity of a chemical compound. This study obtains some topological properties of second and third dominating David derived (DDD) networks and computes several K Banhatti polynomial of second and third type of DDD

Some K-Banhatti Polynomials of First Dominating David Derived Networks

            ترتبط المركبات الكيميائية والخصائص والتراكيب الجزيئية إرتباطا حتمياً. إن المؤشرات التبولوجية هي عبارة عن قيم عددية مرتبطة بالرسوم البيانية الجزيئية الكيميائية التي تساهم في فهم الصفات الفيزيائية للمركب الكيميائي والتفاعل الكيميائي والنشاط البيولوجي. في هذه الدراسة، تم الحصول على بعض الخواص التبولوجية لشبكات مشتقة ديفيد الأولى المهيمنة, وحساب العديد من ممتعددات حدود K-Banhatti من النوع الأول من شبكات مشتقة  ديفيد الأولى المهيمنة.Chemical compounds, characteristics, and molecular structures are inevitably connected. Topological indices are numerical values connected with chemical molecular graphs that contribute to understanding a chemical compounds physical qualities, chemical reactivity, and biological activity. In this study, we have obtained some topological properties of the first dominating David derived (DDD) networks and computed several K-Banhatti polynomials of the first type of DDD

Optimized DWT Based Digital Image Watermarking and Extraction Using RNN-LSTM

The rapid growth of Internet and the fast emergence of multi-media applications over the past decades have led to new problems such as illegal copying, digital plagiarism, distribution and use of copyrighted digital data. Watermarking digital data for copyright protection is a current need of the community. For embedding watermarks, robust algorithms in die media will resolve copyright infringements. Therefore, to enhance the robustness, optimization techniques and deep neural network concepts are utilized. In this paper, the optimized Discrete Wavelet Transform (DWT) is utilized for embedding the watermark. The optimization algorithm is a combination of Simulated Annealing (SA) and Tunicate Swarm Algorithm (TSA). After performing the embedding process, the extraction is processed by deep neural network concept of Recurrent Neural Network based Long Short-Term Memory (RNN-LSTM). From the extraction process, the original image is obtained by this RNN-LSTM method. The experimental set up is carried out in the MATLAB platform. The performance metrics of PSNR, NC and SSIM are determined and compared with existing optimization and machine learning approaches. The results are achieved under various attacks to show the robustness of the proposed work

Stability indicating RP-HPLC method development and validation for the simultaneous estimation of Grazoprevir and Elbasvir in bulk and pharmaceutical dosage form

A simple, Accurate and precise method was developed for the simultaneous estimation of the Grazoprevir and Elbasvir in Tablet dosage form. Chromatogram was run through Kromosil C18 (250 x 4.6 mm), 5m. Mobile phase containing Buffer: Acetonitrile taken in the ratio 45:55 was pumped through column at a flow rate of 1 ml/min. Buffer used in this method was Di Potassium Hydrogen ortho Phosphate. Temperature was maintained at 30°C. Optimized wavelength selected was 215 nm. Retention time of Elbasvir and Grazoprevir and were found to be 2.503 min and 3.004. %RSD of the Elbasvir and Grazoprevir were and found to be 0.3 and 0.4 respectively. %Recovery was obtained as 98.17% and 99.83% for Grazoprevir and Elbasvir respectively. LOD, LOQ values obtained from regression equations of Grazoprevir and Elbasvir were 0.24, 0.73 and 0.06, 0.19 respectively. Retention times were decreased and run time was decreased, so the method developed was simple and economical that can be adopted in regular Quality control test in Industries

ETIOLOGICAL FACTORS FOR THE DEVELOPMENT OF LUNG CANCER IN NON-SMOKERS: AN OVERVIEW

Lung cancer is the most frequent malignant tumour with the highest mortality rate around the world, leading to greater than a million deaths annually. The number of deaths due to lung cancer is expected to increase to ten million deaths per year in 2030. The major risk factor for the development of lung cancer is cigarette smoking but relatively high rates of lung cancer occur among non-smoking women and 10-25% of lung cancer observed in never smokers. The lung cancer deaths occur in never smokers have been estimated to be the 7th leading cause of cancer mortality. This article mainly discusses the important etiological factors of lung cancer in never smokers such as the environmental factors, occupational exposure, history of lung disease, family history and genetic factors, unbalanced diet and high consumption of saturated fat, radiation exposure, socioeconomic status, and infections. Gender, obesity and metabolic syndrome, race and ethnicity and interstitial lung diseases also have effects on the development of lung cancer in never smokers

Randomized clinical study comparing safety and efficacy of adjuvant intrathecal clonidine versus normal saline along with bupivacaine anaesthesia in lower limb surgery patients

Background: Various adjuvants have been used in intrathecal anesthesia to avoid intraoperative visceral and somatic pain and prolong postoperative analgesia. Clonidine, partially selective α2-agonist, is being evaluated as a neuraxial adjuvant with intrathecal bupivacaine. The objective of the study was to evaluate and compare safety and efficacy of intrathecal clonidine as adjuvant to bupivacaine with control normal saline.Methods: American Society of Anesthesiologist grade 1 and 2 patients (60 patients) were randomly divided into two groups of 30 patients each for lower limb surgeries. Study group injected with intrathecal 3ml of 0.5% Bupivacaine heavy (15mg) + 1µg/kg of clonidine and control group injected with 3ml of 0.5% Bupivacaine heavy (15mg) + equivalent dose of normal saline. The onset and duration of sensory and motor block, duration of analgesia, and the incidence of side effects in both groups were observed and compared.Results: Time for 2 segment regressions in study group was 186.17±25.92 minutes compared to control was 103.20±19.15 minutes (p value<0.001). Total duration of analgesia in control was 226.50±35.69 minutes and in the study group was 465.67±100.37 minutes (p value<0.001). The average duration of motor block in control group was 181.17±26.12 minutes compared to study group was 217.80±41.51 minutes (p value<0.001). The small dose of intrathecal clonidine is not significantly associated with systemic side effects such as bradycardia and hypotension.Conclusions: Clonidine added to bupivacaine for intrathecal anesthesia effectively increases the duration of sensory block, duration of motor block and duration of analgesia and does not produce any significant hemodynamic changes. No significant side effects are associated with it