Comparative Analysis of Phraseological Units with Component-Zoonym

The article is devoted to comparative research in Russian, English and Italian phraseological units with the component-zoonym. The relevance of the study is determined by the importance of the analysed units to understand the peculiarities of mentality of representatives of different linguistic cultures and improving intercultural communication, since these idioms demonstrate the commonality and difference in values, stereotypes and behaviour patterns in national cultures. This article gives a review of the scientific literature devoted to the study of zoonyms and presents results of own research. Its novelty is seen in the fact that a detailed classification of phraseological units with the component-zoonym is proposed on the basis of the analysis of their structural and semantic peculiarities on the material of three non-closely related languages. According to the structure there are substantive, adjectival, verbal and adverbial idioms. Within the structural groups according to the semantics there are subgroups used to describe a person, his experience, status, positive and negative qualities, typical properties, emotional and physical condition, behaviour, speech, interpersonal relations etc. The attention is paid to evaluative connotations of the considered units. The dominant images in phraseology of Russian, English and Italian languages are identified and their meanings are examined in the comparative aspect

The analysis of technical solutions for medical ozonators

The article deals with the basic principles of control systems construction in the medical ozone generators. The authors present and analyzes the specific diagram of the electrical and pneumatic part of ozonator. According to analysis results the authors give recommendations for the considered systems realization in the medical ozone generators

Development of Biotechnology for Anthrax Bacteriophages Reproduction, and Comparative Analysis of Their Properties Stability and Diagnostic Value

Carried out has been complex comparative analysis of the production and diagnostic properties of such anthrax bacteriophages as Gamma A-26, Fah-RRIVV&M (Russian Research Institute of Veterinary Virology and Microbiology), R/D-Ph-6, BA-9, K RRIEV (Russian Research Institute of Experimental Veterinary), Saratov, and 186. It is revealed that all of the bacteriophages have the properties necessary for using them for preparation manufacturing purposes: they readily proliferate in liquid cultures of avirulent Bacillus anthracis strain - STI, and retain sufficient specific activity if stored at the optimum temperatures or, when exposed to short-term temperature excursions, within a period of two years. Most clearly expressed are the differences in diagnostic properties of the bacteriophages - specific activity and specificity. Put forward are the groups of bacteriophages that are the most relevant for identification or phage-typing of B. anthracis strains

USP49 deubiquitinase regulates the mitotic spindle checkpoint and prevents aneuploidy.

The spindle assembly checkpoint (SAC) is an essential mechanism that ensures the accurate chromosome segregation during mitosis, thus preventing genomic instability. Deubiquitinases have emerged as key regulators of the SAC, mainly by determining the fate of proteins during cell cycle progression. Here, we identify USP49 deubiquitinase as a novel regulator of the spindle checkpoint. We show that loss of USP49 in different cancer cell lines impairs proliferation and increases aneuploidy. In addition, USP49-depleted cells overcome the arrest induced by the SAC in the presence of nocodazole. Finally, we report new binding partners of USP49, including ribophorin 1, USP44, and different centrins.We thank A.P. Ugalde, D. Rodríguez, J.G. Pérez-Silva, Y. Español and F. Rodríguez for helpful comments and advice. We also thank S.A. Miranda, D. Álvarez-Puente and C. Garabaya for excellent technical assistance, as well as the staff of the scientific core facilities from the University of Oviedo (Unidad de Ensayos Biotecnológicos y Biomédicos, Servicios Científico-Técnicos). This work was supported by the Ministerio de Ciencia e Innovación (SAF2017-87655-R, PDI2020-118394RB-100 and PGC2018- 097019-B-I00), “la Caixa” Banking Foundation (project code HR17-00247), and the European Research Council (742067, DeAge). The IUOPA is funded by the Asturian Government and Fundación Cajastur-Liberbank.S

Peculiarities of Spatial Structure of the Central Caucasian High-Mountain Natural Plague Focus

Within the limits of Central Caucasian high-mountain natural plague focus discovered are two zones of natural focality. The first natural focality zone in the mountain steppe of the eastern part of the focus has a parasitic complex similar in structural organization and functioning to lowland foci of the souslik type. Another one, situated in the western part of the focus, is compatible with Tuva mountain natural plague focus, where fleas Neopsylla setosaare absent, and epizootic activity is characterized by a single-humped curve with an apex for July-August period. The similarities stated above can be used for optimization of epidemiological surveillance techniques, preventive measures, and methodology of studying mountain natural plague foci of the souslik type

Tissue-specific effects of central leptin on the expression of genes involved in lipid metabolism in liver and white adipose tissue

Copyright (2007) The Endocrine Society .The paper can be found at the following URL on the website http://endo.endojournals.org

RENAL SYMPTOM: VARIANTS OF INTERPRETATION

Clinical task.Parents of a 3.5-year-old girl consulted a doctor due to the girl’s unusual urine color.The day before the girl had been complaining of pains in the lower abdomen. The girl urinated at night; in the morning the father discovered that the urine was bright crimson