Statistics of the electromagnetic response of a chaotic reverberation chamber

This article presents a study of the electromagnetic response of a chaotic reverberation chamber (RC) in the presence of losses. By means of simulations and of experiments, the fluctuations in the maxima of the field obtained in a conventional mode-stirred RC are compared with those in a chaotic RC in the neighborhood of the Lowest Useable Frequency (LUF). The present work illustrates that the universal spectral and spatial statistical properties of chaotic RCs allow to meet more adequately the criteria required by the Standard IEC 61000-4-21 to perform tests of electromagnetic compatibility.Comment: 6 pages, 9 figure

An in situ instrument for planar O2 optode measurements at benthic interfaces

A new in situ instrument for two‐dimensional mapping of oxygen in coastal sediments is presented. The measuring principle is described, and potential mechanical disturbances, solute and particle smearing associated with the measurements, and calibration routines are evaluated. The first in situ measurements obtained in two different benthic communities are presented. In a shallow photosynthetic sediment (1 m of water depth), an extensive horizontal and temporal variation in the O2 distribution caused by benthic photosynthesis and irrigating fauna was resolved. Repetitive planar optode measurements performed along a transect in central Øresund, Denmark (17 m of water depth) revealed a positive correlation between the apparent O2 penetration depths (OP) measured with a lateral distance <5.0 mm, whereas OP measured with a larger horizontal distance (up to 50 m) were not correlated. Consequently, the OP varied in patches with a characteristic size of 5.0 mm. The instrument described is a powerful new tool for in situ characterization of spatiotemporal variations in O2 distributions within benthic communities. The instrument can be adapted for use at full ocean depths, e.g., on deep‐sea landers or remote operating vehicles

Inhomogeneous losses and complexness of wave functions in chaotic cavities

In a two-dimensional microwave chaotic cavity Ohmic losses located at the contour of the cavity result in different broadenings of different modes. We provide an analytic description and establish the link between such an inhomogeneous damping and the complex (non-real) character of biorthogonal wave functions. This substantiates the corresponding recent experimental findings of Barthélemy et al. (Europhys. Lett., 70 (2005) 162)

Computational modeling of growth: systemic and pulmonary hypertension in the heart

We introduce a novel constitutive model for growing soft biological tissue and study its performance in two characteristic cases of mechanically induced wall thickening of the heart. We adopt the concept of an incompatible growth configuration introducing the multiplicative decomposition of the deformation gradient into an elastic and a growth part. The key feature of the model is the definition of the evolution equation for the growth tensor which we motivate by pressure-overload-induced sarcomerogenesis. In response to the deposition of sarcomere units on the molecular level, the individual heart muscle cells increase in diameter, and the wall of the heart becomes progressively thicker. We present the underlying constitutive equations and their algorithmic implementation within an implicit nonlinear finite element framework. To demonstrate the features of the proposed approach, we study two classical growth phenomena in the heart: left and right ventricular wall thickening in response to systemic and pulmonary hypertension

Microwave realization of quasi one-dimensional systems with correlated disorder

A microwave setup for mode-resolved transport measurement in quasi-one-dimensional (quasi-1D) structures is presented. We will demonstrate a technique for direct measurement of the Green's function of the system. With its help we will investigate quasi-1D structures with various types of disorder. We will focus on stratified structures, i.e., structures that are homogeneous perpendicular to the direction of wave propagation. In this case the interaction between different channels is absent, so wave propagation occurs individually in each open channel. We will apply analytical results developed in the theory of one-dimensional (1D) disordered models in order to explain main features of the quasi-1D transport. The main focus will be selective transport due to long-range correlations in the disorder. In our setup, we can intentionally introduce correlations by changing the positions of periodically spaced brass bars of finite thickness. Because of the equivalence of the stationary Schr\"odinger equation and the Helmholtz equation, the result can be directly applied to selective electron transport in nanowires, nanostripes, and superlattices.Comment: 11 pages, 9 figure

Transition from Gaussian-orthogonal to Gaussian-unitary ensemble in a microwave billiard with threefold symmetry

Recently it has been shown that time-reversal invariant systems with discrete symmetries may display in certain irreducible subspaces spectral statistics corresponding to the Gaussian unitary ensemble (GUE) rather than to the expected orthogonal one (GOE). A Kramers type degeneracy is predicted in such situations. We present results for a microwave billiard with a threefold rotational symmetry and with the option to display or break a reflection symmetry. This allows us to observe the change from GOE to GUE statistics for one subset of levels. Since it was not possible to separate the three subspectra reliably, the number variances for the superimposed spectra were studied. The experimental results are compared with a theoretical and numerical study considering the effects of level splitting and level loss

NS1 Specific CD8(+) T-Cells with Effector Function and TRBV11 Dominance in a Patient with Parvovirus B19 Associated Inflammatory Cardiomyopathy

Background: Parvovirus B19 (B19V) is the most commonly detected virus in endomyocardial biopsies (EMBs) from patients with inflammatory cardiomyopathy (DCMi). Despite the importance of T-cells in antiviral defense, little is known about the role of B19V specific T-cells in this entity. Methodology and Principal Findings: An exceptionally high B19V viral load in EMBs (115,091 viral copies/mg nucleic acids), peripheral blood mononuclear cells (PBMCs) and serum was measured in a DCMi patient at initial presentation, suggesting B19V viremia. The B19V viral load in EMBs had decreased substantially 6 and 12 months afterwards, and was not traceable in PBMCs and the serum at these times. Using pools of overlapping peptides spanning the whole B19V proteome, strong CD8(+) T-cell responses were elicited to the 10-amico-acid peptides SALKLAIYKA (19.7% of all CD8(+) cells) and QSALKLAIYK (10%) and additional weaker responses to GLCPHCINVG (0.71%) and LLHTDFEQVM (0.06%). Real-time RT-PCR of IFN gamma secretion-assay-enriched T-cells responding to the peptides, SALKLAIYKA and GLCPHCINVG, revealed a disproportionately high T-cell receptor Vbeta (TRBV) 11 expression in this population. Furthermore, dominant expression of type-1 (IFN gamma, IL2, IL27 and Tbet) and of cytotoxic T-cell markers (Perforin and Granzyme B) was found, whereas gene expression indicating type-2 (IL4, GATA3) and regulatory T-cells (FoxP3) was low. Conclusions: Our results indicate that B19V Ag-specific CD8(+) T-cells with effector function are involved in B19V associated DCMi. In particular, a dominant role of TRBV11 and type-1/CTL effector cells in the T-cell mediated antiviral immune response is suggested. The persistence of B19V in the endomyocardium is a likely antigen source for the maintenance of CD8(+) T-cell responses to the identified epitopes

Implementing Non-Universal Features with a Random Matrix Theory Approach: Application to Space-to-Configuration Multiplexing

We consider the efficiency of multiplexing spatially encoded information across random configurations of a metasurface-programmable chaotic cavity in the microwave domain. The distribution of the effective rank of the channel matrix is studied to quantify the channel diversity and to assess a specific system's performance. System-specific features such as unstirred field components give rise to nontrivial inter-channel correlations and need to be properly accounted for in modelling based on random matrix theory. To address this challenge, we propose a two-step hybrid approach. Based on an ensemble of experimentally measured scattering matrices for different random metasurface configurations, we first learn a system-specific pair of coupling matrix and unstirred contribution to the Hamiltonian, and then add an appropriately weighted stirred contribution. We verify that our method is capable of reproducing the experimentally found distribution of the effective rank with good accuracy. The approach can also be applied to other wave phenomena in complex media

Transmission in waveguides with compositional and structural disorder: experimental effects of disorder cross-correlations

We analyse the single-mode transmission of microwaves in a guide with internal random structure. The waveguide contains scatterers characterised by random heights and positions, corresponding to compositional and structural disorder. We measure the effects of cross-correlations between two kinds of disorder, showing how they enhance or attenuate the experimentally found transmission gaps generated by long-range self-correlations. The results agree with the theoretical predictions obtained for the aperiodic Kronig-Penney model and prove that self- and cross-correlations have relevant effects also in finite disordered samples of small size.Comment: 15 pages, 8 figure