12 research outputs found
MOTOR ABILITIES OF CHILDREN IN URBAN AND RURAL AREAS
Knowledge of motor skills in young schoolchildren is directly related to the effects of physical education and the development of certain motor skills. During the younger school age, the dynamics of the development change is slower when compared to the development of preschoolers. The general mobility factor which, according to most authors, exists during the pre-school age begins to vary during the first few years of elementary school, and this is precisely the period in which children quickly develop their motor skills. The aim of this study is to determine the differences in the motor abilities of students in urban and rural areas. The sample in this study consisted of fourth-grade elementary school students (N = 120) in the municipality of Vranje. The data processing was carried out with the help of the T-test and X2 test. What was tested was the explosive strength, speed of movement frequency, repetitive strength of the trunk and flexibility. Each test of motor ability is covered with at least three variables, and in any case, it did not happen that one group had better results in all three variables that are used for the estimation of some motor skills. Students from urban areas showed significantly better results in explosive strength of the upper limbs (MBCM) and the flexibility of the lower extremities (MDPR and MPRS). Students from rural areas showed significantly better results in speed-frequency movements of the arms and legs (MKRR and MKRN) and the repetitive strength of the trunk (MPNL and MZTL). The number of schoolchildren from urban areas who participate in sports is not significantly different from the number of schoolchildren from rural areas who are involved in sports. The difference that occurs in some variables of motor skills is most likely a consequence of specific training in the context of some field of sport, the quality of training in the field, genetics and physical activity during leisure time
Cross-reactivity of anti-galactocerebroside autoantibodies with a Trypanosoma brucei proteolipidic epitope
Pathogenic mechanisms of the demyelinating encephalopathy featuring the nervous phase of human African trypanosomiasis (HAT) are largely unknown. They might include autoimmune disorders. A variety of autoantibodies is detected during the disease and we have previously evidenced anti-galactocerebroside (GalC) antibodies in the serum and cerebrospinal fluid (CSF) from patients in the nervous stage (stage II) of HAT. We now show that anti-GalC antibodies recognize an antigen located on the parasite membrane and common to different strains of trypanosomes. By using affinity chromatography with a rabbit anti-GalC antiserum, a 52-kD proteolipid was isolated from the membrane of Trypanosoma brucei (T. b.) brucei AnTat 1.9, AnTat 1.1E, and T. b. rhodesiense Etat 1.2/R and Etat 1.2/S. Antibodies directed against this antigen were found in the CSF from patients with nervous stage HAT. These CSF also contained anti-GalC antibodies and adsorption with the proteolipid decreased anti-GalC reactivity. Immunization of mice with this antigen induced the production of antibodies which cross-reacted with GalC but no protection from experimental infection with T. b. brucei. These data support the hypothesis that anti-GalC antibodies detected in the CSF from HAT patients might be induced by molecular mimicry with a parasite antigen