411 research outputs found
Impact of High-Temperature, High-Pressure Synthesis Conditions on the Formation of the Grain Structure and Strength Properties of Intermetallic Ni[3]Al
The impact of the preliminary load on 3Ni+Al powder mixture and the impact of the duration of the delay in application of compacting pressure to synthesis product under the conditions of continuous heating of the mixture up to its self-ignition on the grain size and strength properties of the synthesized Ni[3]Al intermetallide material have been studied. The grain structure of the intermetallide synthesized under pressure was studied by means of metallography, transmission electron microscopy and EBSD analysis, with the dependence of ultimate tensile strength on the grain size in the synthesized intermetallide having been investigated at room temperature and at temperatures up to 1000Β°Π‘. It is shown that an increase in the pressure preliminarily applied to the initial mixture compact results in reduced grain size of the final intermetallide, whereas an increase in pre-compaction time makes the grain size increased. A decrease in the grain size increases the ultimate tensile strength of the intermetallide. The maximum value of the ultimate tensile strength in the observed anomalous temperature dependence of this strength exhibits a shift by 200Β°Π‘ toward higher temperatures, and the ultimate strength of the synthesized intermetallide at 1000Β°Π‘ increases roughly two-fold
Adaptive reactions of cardiovascular system of boys with different level of sexual maturity to physical exercise
Graduated physical exercise with the moderate power (50% of PWC170) induces marked change in such cardiovascular system indices as stroke volume and cardiac output, heart rate in boys with the age of 11-16 years. The nature of reactions of the boys' cardiovascular systems rapid adaptation to physical exercise during adolescence period of ontogenesis depends on the level of their sexual maturity. The boys with the 1st and the 2nd grades of sexual maturity demonstrate the reactions to exercise with the highest growth of heart rate, while the highest growth of cardiac output is typical for the boys with the 3-5th grades of sexual maturity. It was revealed that for the boys with the 3-4th sexual maturity stages the reactions to physical activity were expressed in the maximum values of stroke volume and cardiac output and the recovery period for the investigated parameters was rather extended. At this stage of the boys' development the recovery of cardiac output to the level at rest has a non-linear nature, there can be observed a "negative phase" in the heart rate recovery which can be considered as a symptom of excessive response, unfavorable cardiovascular system reaction to physical exercise
Sympathoadrenal system activity of various puberty stages boys
Β© Medwell Journals, 2016.The catecholamin egestion dynamics analysis and DOFA for teenagers of different sexual maturity level and hormonal and media link becoming of the Sympathoadrenal System (SAS) in the course of boys puberty is carried out. Researches showed that SAS activity for teenagers in the course of puberty changes undulantly. The intensive increase of adrenaline egestion is revealed for boys of 3 puberty stages, the maximal increase of noradrenaline is noted for boys of 4th Puberty Stage (PS) then intensively decreases on 5th PS. Increase in dopamine and DOFA egestion reflect increase of reserve abilities of SAS on 5th puberty stage. Formation of SAS hormonal link for teenage boys happens earlier than that of the medial link: increase of SAS hormonal link activity is noted for boys on 1 -2 PS and decreases on 3-4 PS where activity of SAS medial link is higher. On 5th PS the relative stability of all studied parameters which size during this period comes nearer to definitive level reflecting the relative SAS maturity for boys and particular degree of SAS formation processes completeness within the studied age range takes place
NPY<inf>1</inf> Receptors Participate in the Regulation of Myocardial Contractility in Rats
Β© 2017, Springer Science+Business Media New York.Selective agonist (Leu(31)Pro(34)NPY) and blocker (BIBP-3226) of NPY1 receptors were used to determine the type of NPY receptors involved in myocardial contraction. Experiments with isometric contraction of myocardial strips from mature rats showed that the agonist produced the most potent effect in a concentration of 10β7 M. In this concentration, Leu(31)Pro(34)NPY showed the greatest positive inotropic effect on the contraction of the atria and ventricles. In contrast, selective blocker BIBP-3226 reduced the force of myocardial contractions. Pretreatment of myocardial strips with this blocker abolished the positive inotropic effect of Leu(31)Pro(34)NPY, which attested to important role of NPY1 receptors in myocardial contraction
HERBARIUM SPECIMENS OF WILD CHILEAN POTATO SPECIES BELONGING TO THE SECTION <i> PETOTA </i> DUMORT. GENUS <i> SOLANUM </i> L. IN THE VIR HERBARIUM
A revision of herbarium specimens of Chilean potato species belonging to the section Petota Dumort. genus Solanum L. was conducted. The VIR herbarium [WIR] has 25 specimen sheets of five species: Solanum leptostigma Juz., S. maglia Schlechtd., S. molinae Juz., S. ochoanum Lechn., S. zykinii Lechn. Authentic materials from S.V. Yuzepczuk and V.S. Lehnovich have been identified, namely syntypes of S. molinae , S. ochoanum and S. zykinii. The neotypification of S. leptostigma was done
Dielectric behavior of C6 rat glioma cell monolayer growing on CNT- and Ce- contained nanostructurezed LB-films
Structure and Microhardness of Coatings Fabricated by Non-Vacuum Electron Beam Surfacing of WC Powder on Aluminum Alloy AMg6
The aim of work: to determine the structure and microhardness of WC coatings fabricated by method of non-vacuum electron-beam surfacing onto the AMg6 matrix. The results of measuring the microhardness of coatings showed that its increase occurs by 19-23% compared to the AMg6 matrix.ΠΠ²ΡΠΎΡΡ Π²ΡΡΠ°ΠΆΠ°ΡΡ Π±Π»Π°Π³ΠΎΠ΄Π°ΡΠ½ΠΎΡΡΡ ΠΠΎΠ»ΠΊΠΎΠ²ΡΠΊΠΎΠΌΡ ΠΠΈΡ
Π°ΠΈΠ»Ρ ΠΠ΅Π΄Π°Π»ΠΈΠ΅Π²ΠΈΡΡ (ΠΠ½ΡΡΠΈΡΡΡ ΡΠ΄Π΅ΡΠ½ΠΎΠΉ ΡΠΈΠ·ΠΈΠΊΠΈ ΠΈΠΌ. Π. Π. ΠΡΠ΄ΠΊΠ΅pΠ° Π‘Π Π ΠΠ) Π·Π° ΠΎΠΊΠ°Π·Π°Π½Π½ΡΡ ΠΏΠΎΠΌΠΎΡΡ Π² ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ΠΈΠΈ ΡΠ»Π΅ΠΊΡΡΠΎΠ½Π½ΠΎ-Π»ΡΡΠ΅Π²ΠΎΠΉ Π½Π°ΠΏΠ»Π°Π²ΠΊΠΈ
ΠΠ°ΠΊΠΎΠ½ΠΎΠΌΠ΅ΡΠ½ΠΎΡΡΠΈ ΡΠ΅Π³Π΅Π½Π΅ΡΠ°ΡΠΈΠΈ ΠΊΠΎΠ½ΡΡΠ½ΠΊΡΠΈΠ²Ρ ΠΈ ΡΠΊΠ»Π΅ΡΡ ΠΏΠΎΡΠ»Π΅ ΠΈΠ½ΡΡΠ°ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½ΠΎΠΉ Π°ΠΏΠΏΠ»ΠΈΠΊΠ°ΡΠΈΠΈ ΡΠ°ΡΡΠ²ΠΎΡΠ° ΡΠΈΠΊΠ»ΠΎΡΠΏΠΎΡΠΈΠ½Π° Π Ρ ΠΊΡΠΎΠ»ΠΈΠΊΠΎΠ² ΡΠΎ ΡΡΠ΅ΡΠΎΠΈΠ΄Π½ΠΎΠΉ ΠΌΠΎΠ΄Π΅Π»ΡΡ Π³Π»Π°ΡΠΊΠΎΠΌΡ
Β Aim. In an in vivo experiment, to study the effect of local intraoperative application of 0.05% cyclosporin A solution on the conjunctival and scleral regeneration after surgery on the rabbit eyes with steroid-inducedΒ glaucoma.Materials and methods. At the first stage of the experiment, a model of steroid-induced glaucoma was reproduced for 29 male Californian rabbits by injecting 0.5 ml of a 0.4% solution of dexamethasone subconjunctivally in both eyes once a week for 3 months (12 subconjunctival injections for each rabbit). At the second stage of the experiment, after the development ofΒ steroid glaucoma, the rabbits were divided into the main group, consistingΒ of the subgroup Β«aΒ» (n = 8) and the subgroup Β«bΒ» (n = 8), and the comparison group (n = 8). All animals were performed a penetrating incision of the conjunctiva and a non-penetrating incision of the sclera of one of the eyes. A hemostatic sponge impregnated with 0.05% cyclosporin Π solution was applied to the intervention area in the main group, in the subgroup Β«aΒ» β for 3 minutes, in the subgroup Β«bΒ» β for 6 minutes. In the comparison group, the cytostatic was not used.Results. The use of 0.05% cyclosporin Π solution led to a decrease in theΒ infiltration of fibroblasts and inflammatory cells into the area of surgicalΒ injury. On the 4th day after the surgery, cell density in the intervention areaΒ in the subgroup Β«aΒ» with 3-minute application of cytostatic-antimetabolite solution was 2.7 times lower (p = 0.043) than in the comparison group, while exceeding the values in the subgroup Β«bΒ» by 3.2 times (p = 0.036). The number of fibroblasts in the subgroups Β«aΒ» and Β«bΒ» was 3.6 (p = 0.043) and 12.8 times (p = 0.031) less than in the comparison group, and a shift in the cellular composition of the infiltrate towards the fibroblastic population occurred only on the 14th day after the surgery.Conclusion. Intraoperative application of 0.05% cyclosporin Π solution significantly slows down the course of regeneration, reducing infiltrative inflammation in the intervention area, which prevents excessive scarring.Β Β Π¦Π΅Π»Ρ. Π ΡΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ΅ in vivo ΠΈΠ·ΡΡΠΈΡΡ Π²Π»ΠΈΡΠ½ΠΈΠ΅ ΠΌΠ΅ΡΡΠ½ΠΎΠΉ ΠΈΠ½ΡΡΠ°ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½ΠΎΠΉ Π°ΠΏΠΏΠ»ΠΈΠΊΠ°ΡΠΈΠΈ 0,05%-Π³ΠΎ ΡΠ°ΡΡΠ²ΠΎΡΠ° (Ρ-ΡΠ°) ΡΠΈΠΊΠ»ΠΎΡΠΏΠΎΡΠΈΠ½Π° Π Π½Π° ΡΠ΅Π³Π΅Π½Π΅ΡΠ°ΡΠΈΡ ΠΊΠΎΠ½ΡΡΠ½ΠΊΡΠΈΠ²Ρ ΠΈ ΡΠΊΠ»Π΅ΡΡΒ ΠΏΠΎΡΠ»Π΅ ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΈ Π½Π° Π³Π»Π°Π·Π°Ρ
ΠΊΡΠΎΠ»ΠΈΠΊΠΎΠ² ΡΠΎ ΡΡΠ΅ΡΠΎΠΈΠ΄Π½ΠΎΠΉΒ Π³Π»Π°ΡΠΊΠΎΠΌΠΎΠΉ.ΠΠ°ΡΠ΅ΡΠΈΠ°Π»Ρ ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ. ΠΠ° I ΡΡΠ°ΠΏΠ΅ ΡΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ° 29 ΡΠ°ΠΌΡΠ°ΠΌΒ ΠΊΡΠΎΠ»ΠΈΠΊΠΎΠ² ΠΊΠ°Π»ΠΈΡΠΎΡΠ½ΠΈΠΉΡΠΊΠΎΠΉ ΠΏΠΎΡΠΎΠ΄Ρ ΠΌΠΎΠ΄Π΅Π»ΠΈΡΠΎΠ²Π°Π»ΠΈΒ ΡΡΠ΅ΡΠΎΠΈΠ΄Π½ΡΡ Π³Π»Π°ΡΠΊΠΎΠΌΡ ΠΏΡΡΠ΅ΠΌ Π²Π²Π΅Π΄Π΅Π½ΠΈΡ ΠΏΠΎΠ΄ ΠΊΠΎΠ½ΡΡΠ½ΠΊΡΠΈΠ²ΡΒ ΠΎΠ±ΠΎΠΈΡ
Π³Π»Π°Π· 0,5 ΠΌΠ» 0,4%-Π³ΠΎ Ρ-ΡΠ° Π΄Π΅ΠΊΡΠ°ΠΌΠ΅ΡΠ°Π·ΠΎΠ½Π° 1 ΡΠ°Π· Π² Π½Π΅Π΄ Π² ΡΠ΅ΡΠ΅Π½ΠΈΠ΅ 3 ΠΌΠ΅Ρ (12 ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠΉ). ΠΠ° II ΡΡΠ°ΠΏΠ΅ ΡΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ°, ΠΏΠΎΡΠ»Π΅ ΡΠ°Π·Π²ΠΈΡΠΈΡ ΡΡΠ΅ΡΠΎΠΈΠ΄Π½ΠΎΠΉ Π³Π»Π°ΡΠΊΠΎΠΌΡ, ΠΊΡΠΎΠ»ΠΈΠΊΠΎΠ² ΡΠ°Π·Π΄Π΅Π»ΠΈΠ»ΠΈ Π½Π° ΠΎΡΠ½ΠΎΠ²Π½ΡΡ Π³ΡΡΠΏΠΏΡ, ΡΠΎΡΡΠΎΡΡΡΡ ΠΈΠ· ΠΏΠΎΠ΄Π³ΡΡΠΏΠΏΡ Β«aΒ» (n = 8) ΠΈ ΠΏΠΎΠ΄Π³ΡΡΠΏΠΏΡ Β«bΒ» (n = 8), ΠΈ Π³ΡΡΠΏΠΏΡ ΡΡΠ°Π²Π½Π΅Π½ΠΈΡ (n = 8). ΠΡΠ΅ΠΌ ΠΆΠΈΠ²ΠΎΡΠ½ΡΠΌ Π²ΡΠΏΠΎΠ»Π½ΡΠ»ΠΈ ΡΠΊΠ²ΠΎΠ·Π½ΠΎΠΉ ΡΠ°Π·ΡΠ΅Π· ΠΊΠΎΠ½ΡΡΠ½ΠΊΡΠΈΠ²Ρ ΠΈ Π½Π΅ΠΏΡΠΎΠ½ΠΈΠΊΠ°ΡΡΠΈΠΉ Π½Π°Π΄ΡΠ΅Π· ΡΠΊΠ»Π΅ΡΡ ΠΎΠ΄Π½ΠΎΠ³ΠΎ ΠΈΠ· Π³Π»Π°Π·. ΠΠ° ΠΎΠ±Π»Π°ΡΡΡ Π²ΠΌΠ΅ΡΠ°ΡΠ΅Π»ΡΡΡΠ²Π° Π² ΠΎΡΠ½ΠΎΠ²Π½ΠΎΠΉ Π³ΡΡΠΏΠΏΠ΅ Π½Π°ΠΊΠ»Π°Π΄ΡΠ²Π°Π»ΠΈ Π³Π΅ΠΌΠΎΡΡΠ°ΡΠΈΡΠ΅ΡΠΊΡΡ Π³ΡΠ±ΠΊΡ, ΠΏΡΠΎΠΏΠΈΡΠ°Π½Π½ΡΡ 0,05%-ΠΌ Ρ-ΡΠΎΠΌ ΡΠΈΠΊΠ»ΠΎΡΠΏΠΎΡΠΈΠ½Π° Π, Π² ΠΏΠΎΠ΄Π³ΡΡΠΏΠΏΠ΅ Β«Π°Β» Π½Π° 3 ΠΌΠΈΠ½, Π² ΠΏΠΎΠ΄Π³ΡΡΠΏΠΏΠ΅ Β«bΒ» β Π½Π° 6 ΠΌΠΈΠ½. Π Π³ΡΡΠΏΠΏΠ΅ ΡΡΠ°Π²Π½Π΅Π½ΠΈΡ ΡΠΈΡΠΎΡΡΠ°ΡΠΈΠΊ Π½Π΅ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π»ΠΈ.Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. ΠΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ 0,05%-Π³ΠΎ Ρ-ΡΠ° ΡΠΈΠΊΠ»ΠΎΡΠΏΠΎΡΠΈΠ½Π° ΠΒ ΠΏΡΠΈΠ²Π΅Π»ΠΎ ΠΊ ΡΠΌΠ΅Π½ΡΡΠ΅Π½ΠΈΡ ΠΈΠ½ΡΠΈΠ»ΡΡΡΠ°ΡΠΈΠΈ Π·ΠΎΠ½Ρ Ρ
ΠΈΡΡΡΠ³ΠΈΡΠ΅ΡΠΊΠΎΠΉΒ ΡΡΠ°Π²ΠΌΡ Π²ΠΎΡΠΏΠ°Π»ΠΈΡΠ΅Π»ΡΠ½ΡΠΌΠΈ ΠΊΠ»Π΅ΡΠΊΠ°ΠΌΠΈ ΠΈ ΡΠΈΠ±ΡΠΎΠ±Π»Π°ΡΡΠ°ΠΌΠΈ. ΠΠ° 4- Π΅ ΡΡΡ ΠΏΠΎΡΠ»Π΅ ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΈ ΠΊΠ»Π΅ΡΠΎΡΠ½Π°Ρ ΠΏΠ»ΠΎΡΠ½ΠΎΡΡΡ Π² ΠΎΠ±Π»Π°ΡΡΠΈ Π²ΠΌΠ΅ΡΠ°ΡΠ΅Π»ΡΡΡΠ²Π° Π² ΠΏΠΎΠ΄Π³ΡΡΠΏΠΏΠ΅ Β«Π°Β» ΠΎΡΠ½ΠΎΠ²Π½ΠΎΠΉ Π³ΡΡΠΏΠΏΡ Ρ ΡΡΠ΅Ρ
ΠΌΠΈΠ½ΡΡΠ½ΠΎΠΉ Π°ΠΏΠΏΠ»ΠΈΠΊΠ°ΡΠΈΠ΅ΠΉ Ρ-ΡΠ° ΡΠΈΡΠΎΡΡΠ°ΡΠΈΠΊΠ°-Π°Π½ΡΠΈΠΌΠ΅ΡΠ°Π±ΠΎΠ»ΠΈΡΠ° Π±ΡΠ»Π° Π² 2,7 ΡΠ°Π·Π° ΠΌΠ΅Π½ΡΡΠ΅ (p = 0,043), ΡΠ΅ΠΌ Π²Β Π³ΡΡΠΏΠΏΠ΅ ΡΡΠ°Π²Π½Π΅Π½ΠΈΡ, ΠΏΡΠ΅Π²ΡΡΠ°Ρ ΠΏΡΠΈ ΡΡΠΎΠΌ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»ΠΈ ΠΏΠΎΠ΄Π³ΡΡΠΏΠΏΡ Β«bΒ» Π² 3,2 ΡΠ°Π·Π° (p = 0,036). Π§ΠΈΡΠ»Π΅Π½Π½ΠΎΡΡΡΒ ΡΠΈΠ±ΡΠΎΠ±Π»Π°ΡΡΠΎΠ² Π² ΠΏΠΎΠ΄Π³ΡΡΠΏΠΏΠ°Ρ
Β«Π°Β» ΠΈ Β«bΒ» Π±ΡΠ»Π° Π² 3,6 (p = 0,043) ΠΈ 12,8 ΡΠ°Π·Π° (p = 0,031) Π½ΠΈΠΆΠ΅, ΡΠ΅ΠΌ Π² Π³ΡΡΠΏΠΏΠ΅ ΡΡΠ°Π²Π½Π΅Π½ΠΈΡ. ΠΡΠΈΒ ΡΡΠΎΠΌ ΡΠ΄Π²ΠΈΠ³ ΠΊΠ»Π΅ΡΠΎΡΠ½ΠΎΠ³ΠΎ ΡΠΎΡΡΠ°Π²Π° ΠΈΠ½ΡΠΈΠ»ΡΡΡΠ°ΡΠ° Π² ΡΡΠΎΡΠΎΠ½ΡΒ ΡΠΈΠ±ΡΠΎΠ±Π»Π°ΡΡΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΏΠΎΠΏΡΠ»ΡΡΠΈΠΈ ΠΏΡΠΎΠΈΠ·ΠΎΡΠ΅Π» ΡΠΎΠ»ΡΠΊΠΎ Π½Π° 14-Π΅Β ΡΡΡ ΠΏΠΎΡΠ»Π΅ ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΈ.Β ΠΠ°ΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅. ΠΠ½ΡΡΠ°ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½Π°Ρ Π°ΠΏΠΏΠ»ΠΈΠΊΠ°ΡΠΈΡ 0,05%-Π³ΠΎ Ρ- ΡΠ° ΡΠΈΠΊΠ»ΠΎΡΠΏΠΎΡΠΈΠ½Π° Π ΡΡΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΎ Π·Π°ΠΌΠ΅Π΄Π»ΡΠ΅Ρ ΡΠ΅ΡΠ΅Π½ΠΈΠ΅Β Π²ΠΎΡΠΏΠ°Π»ΠΈΡΠ΅Π»ΡΠ½ΠΎ-ΡΠ΅ΠΏΠ°ΡΠ°ΡΠΈΠ²Π½ΠΎΠΉ ΡΠ΅Π³Π΅Π½Π΅ΡΠ°ΡΠΈΠΈ, ΡΠΌΠ΅Π½ΡΡΠ°ΡΒ ΠΈΠ½ΡΠΈΠ»ΡΡΡΠ°ΡΠΈΠ²Π½ΠΎΠ΅ Π²ΠΎΡΠΏΠ°Π»Π΅Π½ΠΈΠ΅ Π² Π·ΠΎΠ½Π΅ Π²ΠΌΠ΅ΡΠ°ΡΠ΅Π»ΡΡΡΠ²Π°, ΡΡΠΎΒ ΠΏΡΠ΅Π΄ΠΎΡΠ²ΡΠ°ΡΠ°Π΅Ρ ΠΈΠ·Π»ΠΈΡΠ½Π΅Π΅ ΡΡΠ±ΡΠ΅Π²Π°Π½ΠΈΠ΅.
Electro-physical properties of cell monolayer on nanocomposite coating based on carbon nanotubes LB-films
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