Personnel Training for High-tech Industries: The Experience of MEPhI Base Department ‘Semiconductor Quantum Electronics’

Industry is going through a ubiquitous technological renewal that determines the needed competencies of graduates and the content of educational programs offered by universities. Unfortunately, there is an imbalance between the education received and the entrance requirements for a graduate specialist in industry, in the research and development sector. One of the modern forms of interaction between enterprises and the university in the personnel training is the creation of the base department of the enterprise at the university. The article deals with the educational and scientific activity of the base department of the MEPhI ‘Semiconductor quantum electronics’. The base department trains personnel for high-tech industries with the master’s and post-graduate educational programs.     Keywords: personal training, base department, high-tech, semiconductor quantum electronic

Delocalisation transition in quasi-1D models with correlated disorder

We introduce a new approach to analyse the global structure of electronic states in quasi-1D models in terms of the dynamics of a system of parametric oscillators with time-dependent stochastic couplings. We thus extend to quasi-1D models the method previously applied to 1D disordered models. Using this approach, we show that a ``delocalisation transition'' can occur in quasi-1D models with weak disorder with long-range correlations.Comment: 33 pages, no figure

Mobility Edge in Aperiodic Kronig-Penney Potentials with Correlated Disorder: Perturbative Approach

It is shown that a non-periodic Kronig-Penney model exhibits mobility edges if the positions of the scatterers are correlated at long distances. An analytical expression for the energy-dependent localization length is derived for weak disorder in terms of the real-space correlators defining the structural disorder in these systems. We also present an algorithm to construct a non-periodic but correlated sequence exhibiting desired mobility edges. This result could be used to construct window filters in electronic, acoustic, or photonic non-periodic structures.Comment: RevTex, 4 pages including 2 Postscript figure

Local and average fields inside surface-disordered waveguides: Resonances in the one-dimensional Anderson localization regime

We investigate the one-dimensional propagation of waves in the Anderson localization regime, for a single-mode, surface disordered waveguide. We make use of both an analytical formulation and rigorous numerical simulation calculations. The occurrence of anomalously large transmission coefficients for given realizations and/or frequencies is studied, revealing huge field intensity concentration inside the disordered waveguide. The analytically predicted s-like dependence of the average intensity, being in good agreement with the numerical results for moderately long systems, fails to explain the intensity distribution observed deep in the localized regime. The average contribution to the field intensity from the resonances that are above a threshold transmission coefficient $T_{c}$ is a broad distribution with a large maximum at/near mid-waveguide, depending universally (for given $T_{c}$) on the ratio of the length of the disorder segment to the localization length, $L/\xi$. The same universality is observed in the spatial distribution of the intensity inside typical (non-resonant with respect to the transmission coefficient) realizations, presenting a s-like shape similar to that of the total average intensity for $T_{c}$ close to 1, which decays faster the lower is $T_{c}$. Evidence is given of the self-averaging nature of the random quantity $\log[I(x)]/x\simeq -1/\xi$. Higher-order moments of the intensity are also shown.Comment: 9 pages, 9 figure

Analysis of congenital disorder of glycosylation-Id in a yeast model system shows diverse site-specific under-glycosylation of glycoproteins

Asparagine-linked glycosylation is a common post translational modification of proteins in eukaryotes. Mutations in the human ALG3 gene cause changed levels and altered glycan structures on mature glycoproteins and are the cause of a severe congenital disorder of glycosylation (CDG-Id). Diverse glycoproteins are also under-glycosylated in Saccharomyces cerevisae alg3 mutants. Here we analyzed site-specific glycosylation occupancy in this yeast model system using peptide-N-glycosidase F to label glycosylation sites with an asparagine-aspartate conversion that creates a new endoproteinase AspN cleavage site, followed by proteolytic digestion, and detection of peptides and glycopeptides by LC-ESI-MS/MS. We used this analytical method to identify and measure site specific glycosylation occupancy in alg3 mutant and wild type yeast strains. We found decreased site specific N-glycosylation occupancy in the alg3 knockout strain preferentially at Asn-Xaa-Ser sequences located in secondary structural elements, features previously associated with poor glycosylation efficiency. Furthermore, we identified 26 previously experimentally unverified glycosylation sites. Our results provide insights into the underlying mechanisms of disease in CDG-Id, and our methodology will be useful in site specific glycosylation analysis in many model systems and clinical applications

Tractability in Constraint Satisfaction Problems: A Survey

International audienceEven though the Constraint Satisfaction Problem (CSP) is NP-complete, many tractable classes of CSP instances have been identified. After discussing different forms and uses of tractability, we describe some landmark tractable classes and survey recent theoretical results. Although we concentrate on the classical CSP, we also cover its important extensions to infinite domains and optimisation, as well as #CSP and QCSP