Effect of vacuum desalination on heat exchange parameters

On the example of a thermal scheme of a waste-distillation vacuum desalination plant, it is considered how the heat exchange parameters change depending on the time of year and the region of navigation of the vessel or the location of the plant. The performance of the desalination plant depends on the performance of the engine and the temperature of the sea water, since the main engine is cooled by sea water, which in turn is used to heat the heating battery in the desalination plant. In this thermal scheme, water is heated in a heat exchanger, the characteristics of which can be selected the same as those of the main engine of the vessel

Arrhythmic risk profile and outcomes of patients undergoing cardiac sympathetic denervation for recurrent monomorphic ventricular tachycardia after ablation

Background Cardiac sympathetic denervation (CSD) has been used as a bailout strategy for refractory ventricular tachycardia (VT). Risk of VT recurrence in patients with scar-related monomorphic VT referred for CSD and the extent to which CSD can modify this risk is unknown. We aimed to quantify arrhythmia recurrence risk and impact of CSD in this population. Methods and Results Adjusted competing risk time to event models were developed to adjust for risk of VT recurrence and sustained VT/implantable cardioverter-defibrillator shocks after VT ablation based on patient comorbidities at the time of VT ablation. Adjusted VT and implantable cardioverter-defibrillator shock recurrence rates were estimated for the subgroup who subsequently required CSD after ablation. The expected adjusted recurrence rates were then compared with the observed rates after CSD. Data from 381 patients with scar-mediated monomorphic VT who underwent VT ablation were analyzed, excluding patients with polymorphic VT. Sixty eight patients underwent CSD for recurrent VT. CSD reduced the expected adjusted VT recurrence rate by 36% (expected rate of 5.61 versus observed rate of 3.58 per 100 person-months, P=0.01) and the sustained VT/implantable cardioverter-defibrillator shock rates by 34% (expected rate of 4.34 versus observed 2.85 per 100 person-months, P=0.03). The median number of sustained VT/implantable cardioverter-defibrillator shocks in the year before versus the year after CSD was reduced by 90% (10 versus 1, P<0.0001). Conclusions Patients referred for CSD for refractory scar-mediated monomorphic VT are at a higher risk of VT recurrence after ablation as compared with those not requiring CSD, mostly because of their cardiac comorbidities. CSD significantly reduced both the expected risk of recurrences and VT burden

JUNO Conceptual Design Report

The Jiangmen Underground Neutrino Observatory (JUNO) is proposed to determine the neutrino mass hierarchy using an underground liquid scintillator detector. It is located 53 km away from both Yangjiang and Taishan Nuclear Power Plants in Guangdong, China. The experimental hall, spanning more than 50 meters, is under a granite mountain of over 700 m overburden. Within six years of running, the detection of reactor antineutrinos can resolve the neutrino mass hierarchy at a confidence level of 3-4$\sigma$, and determine neutrino oscillation parameters $\sin^2\theta_{12}$, $\Delta m^2_{21}$, and $|\Delta m^2_{ee}|$ to an accuracy of better than 1%. The JUNO detector can be also used to study terrestrial and extra-terrestrial neutrinos and new physics beyond the Standard Model. The central detector contains 20,000 tons liquid scintillator with an acrylic sphere of 35 m in diameter. $\sim$17,000 508-mm diameter PMTs with high quantum efficiency provide $\sim$75% optical coverage. The current choice of the liquid scintillator is: linear alkyl benzene (LAB) as the solvent, plus PPO as the scintillation fluor and a wavelength-shifter (Bis-MSB). The number of detected photoelectrons per MeV is larger than 1,100 and the energy resolution is expected to be 3% at 1 MeV. The calibration system is designed to deploy multiple sources to cover the entire energy range of reactor antineutrinos, and to achieve a full-volume position coverage inside the detector. The veto system is used for muon detection, muon induced background study and reduction. It consists of a Water Cherenkov detector and a Top Tracker system. The readout system, the detector control system and the offline system insure efficient and stable data acquisition and processing.Comment: 328 pages, 211 figure

Ancient DNA of narrow-headed vole reveal common features of the Late Pleistocene population dynamics in cold-adapted small mammals

The narrow-headed vole, collared lemming and common vole were the most abundant small mammal species across the Eurasian Late Pleistocene steppe-tundra environment. Previous ancient DNA studies of the collared lemming and common vole have revealed dynamic population histories shaped by climatic fluctuations. To investigate the extent to which species with similar adaptations share common evolutionary histories, we generated a dataset comprised the mitochondrial genomes of 139 ancient and 6 modern narrow-headed voles from several sites across Europe and northwestern Asia covering approximately the last 100 thousand years (kyr). We inferred Bayesian time-aware phylogenies using 11 radiocarbon-dated samples to calibrate the molecular clock. Divergence of the main mtDNA lineages across the three species occurred during marine isotope stages (MIS) 7 and MIS 5, suggesting a common response of species adapted to open habitat during interglacials. We identified several time-structured mtDNA lineages in European narrow-headed vole, suggesting lineage turnover. The timing of some of these turnovers was synchronous across the three species, allowing us to identify the main drivers of the Late Pleistocene dynamics of steppe- and cold-adapted species.NWOVI.C.191.070Human Origin

Update on prevention and treatment of sudden cardiac arrest

Sudden cardiac arrest is the leading cause of cardiovascular mortality, posing a substantial public health burden. The incidence and epidemiology of sudden death are a function of age, with primary arrhythmia syndromes and inherited cardiomyopathies representing the predominant causes in younger patients, while coronary artery disease being the leading etiology in those who are 35 years of age and older. Internal cardioverter defibrillators remain the mainstay of primary and secondary prevention of sudden cardiac arrest. In the acute phase, cardiac chain of survival, early reperfusion, and therapeutic hypothermia are the key steps in improving outcomes. In the chronic settings, ventricular tachycardia ablation has been shown to improve patients' quality of life by reducing frequency of defibrillator shocks. Moreover, recent studies have suggested that it may increase survival. Neuromodulation represents a novel therapeutic modality that has a great potential for improving treatment of ventricular arrhythmias

Electronic Document Storage and Electronic Document Management System Management of the Organization

В данной статье рассмотрено действующее российское законодательство в области документооборота, выявлены его недостатки и аспекты, которые, по мнению автора, необходимо изменить в соответствии с тенденциями современной экономики. Цель работы – доказать преимущества электронного документооборота. В работе представлены варианты существующих программных решений, основное внимание уделено системам СЭД и ЕМС как наиболее перспективным, сделан акцент на их преимуществах и недостатках. В заключение автором выделены направления, в которых будет развиваться электронный документооборот и какие проблемы еще предстоит решить государству и обществу.This article describes the current Russian law about document turnover, shows advantages and disadvantages of these laws. The author reflects about the aspects that need to be corrected. The goal of the a rticle is to show a benefit of using the digital system of document turnover. The article demonstrate options of real software solutions. In conclusion, the author outlines the direction in which electronic doc ument management should develop and nowadays problems that still need to be resolved by the state and society

The problem of the hybrid nature of modern art on examples of light works by russian and western artists of the XXI century

The article considers the problem of the hybrid nature of modern art on examples of light works by Russian and Western artists of the XXI century. Research objective: to study light art as the separate art phenomenon in Russia and abroad and to reveal his criteria. The author subdivides light works of the Russian and Western artists of the 21st century into the following categories: scientific project, psychological experiment, business show and work of art. If we talk about those examples that are not art, but rather related to the entertainment industry, it's 3D-mapping projects. On the one hand, the appearance of kitsch in one direction or another indicates that this direction has long been formed. On the other hand, the critical evaluation of light art has not yet received, which the author seeks to correct in his article.Статья рассматривает проблему гибридности современного искусства на примерах световых работ российских и западных художников XXI века. Цель исследования — изучить световое искусство как отдельное художественное явление в России и за рубежом и выявить его критерии. Световые работы российских и западных художников XXI века автор подразделяет на следующие категории: научный проект, психологический эксперимент, бизнес-шоу и произведение искусства. Если говорить о тех примерах, которые искусством не является, а, скорее, относятся к индустрии развлечений, то это проекты по 3D-мэппингу. С одной стороны, появление в том или ином направлении кича свидетельствует о том, что данное направление уже давно сложилось. С другой стороны, критической оценки световое искусство до сих пор не получило, что автор стремится исправить в своей статье