152 research outputs found

    Accuracy Evaluation Of Automated Speech Transcription Via User Feedback

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    Effective operation of a voice-activated virtual assistant requires accurate speech recognition. Manual determination of the accuracy of machine-generated speech transcriptions requires involvement of third parties to evaluate transcriptions of a user’s speech. Automated accuracy evaluation approaches that use machine-generated speech as input and determine quality of transcription have limited effectiveness since the machine-generated speech is a poor proxy for real-world user speech, e.g., volume of input, microphone and room characteristics, pronunciations, etc. This disclosure describes obtaining user confirmation of the transcription of a small subset user queries as performed by a virtual assistant or other applications that accept speech input. With user permission, the obtained data, e.g., the user verifying that the transcription was accurate or indicating that it was wrong, are used to rate and/or update the speech recognition technology, e.g., train speech recognition machine learning models

    Respiratory enzymes of the silkmoth Antheraea pernyi in relation to metamorphosis and pupal diapause

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    1. 1. Wing epidermis from diapausing and non-diapausing silkmoths (Antheraea pernyi) was assayed for NADH [nicotinamide adenine dinucleotide (reduced form)] oxidase, NADH- and succinate-cyctochrome c reductases, and cytochrome c oxidase.2. 2. Diapausing pupae showed a marked decline in activities after pupation and the same subsequent profile of very low activities reported for diapausing Cecropia silkmoths.3. 3. Non-diapausing pupae showed only a slight and transient decline after pupation and otherwise retained relatively high activities throughout metamorphosis.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/22213/1/0000646.pd

    Properties and inhibition of thymidylate synthetase in Drosophila melanogaster

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    A quantitative comparison of the incorporation of methyl-3H-thymidine and 6-3H-deoxyuridine into the DNA of Drosophila melanogaster in the presence and in the absence of 5-fluorouracil indicated that 5-fluorouracil inhibits the reaction converting dUMP to dTMP catalysed by thymidylate synthetase (methylenetetrahydrofolate:dUrd-5'-P C-methyltransferase, E.C. 2.1.1.b). The enzyme exhibits maximal activity at pH 7[middle dot]5 to 8[middle dot]0 and is protected from heat inactivation by deoxyuridine monophosphate. The addition of thiol compounds to the homogenization buffer results in the enhancement of synthetase activity. The Km values for deoxyuridine monophosphate and 5,10-methylenetetrahydrofolate are 6[middle dot]8 x 10-6 M and 8[middle dot]3 x 10-5 M, respectively. Fluorodeoxyuridine monophosphate, trifluoromethyldeoxyuridine monophosphate, and methotrexate are inhibitors of the enzyme. 5-Bromodeoxyuridine and 5-iododeoxyuridine have no inhibitory effect. The results support the contention that, under conditions which induce morphological lesions in Drosophila, fluorinated pyrimidines and methotrexate inhibit the de novo synthesis of thymidylate whereas thymidine analogues function in some other manner.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/22328/1/0000773.pd

    INJURY INDUCED MOLTING IN GALLERIA MELLONELLA LARVAE

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    Volume: 142Start Page: 281End Page: 29

    CONTROL OF MOLTING IN MANDIBULATE AND CHELICERATE ARTHROPODS BY ECDYSONES

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    Volume: 139Start Page: 520End Page: 53
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