“HAITIANOS: RESPEITO, CULTURA E DIFERENÇAS”: RELATO DE EXPERIÊNCIA SOBRE O PROJETO

A partir de 2010, o Brasil passou a receber um número expressivo de imigrantes haitianos. Na região Oeste de Santa Catarina, a migração haitiana foi incentivada pela agroindústria presente na região, em função do emprego de grande número de trabalhadores. Em uma região marcada pela mítica de um passado heróico dos imigrantes alemães e italianos e com a evocação constante de uma identidade europeia, portanto, branca, não surpreendeu que esses imigrantes haitianos foram alvo de racismo pela população local, além de ser perceptível a insociabilidade entre a população local e os imigrantes haitianos. Pensando na integração, dentro das possibilidades, desses imigrantes haitianos, porém buscando principalmente combater o racismo, percebeu-se que o espaço escolar seria um importante ponto de partida para desenvolver o respeito e a tolerância. Sendo assim, criou-se o projeto de cultura “Haitianos: Respeito, Cultura e Diferenças”, vinculado a UFFS, campus Chapecó. O objetivo do projeto é oferecer minicursos sobre a história do Haiti, o contexto atual e a imigração haitiana para o Brasil, além de discutir sobre o preconceito e o racismo, visando estimular a empatia e o respeito às diferenças entre os adolescentes frequentadores das escolas públicas da cidade. No segundo semestre de 2018, as atividades aconteceram na Escola Básica Profª Valesca Parizotto, com duas turmas do 9º ano do Ensino Fundamental, atendendo um total de 60 alunos. Os resultados obtidos até o momento indicam uma melhora da integração entre os discentes moradores da região e os discentes imigrantes haitianos, os quais muitas vezes estavam na mesma turma, porém não socializavam entre si. Além disso, os discentes foram estimulados a desenvolver textos, desenhos e história em quadrinhos sobre a imigração haitiana, contudo grande parte deles apresentaram principalmente apelos contra o racismo, o que comprova o quão efetivo foi o desenrolar do projeto

Polimorfismos gen?tico e proteico da enzima conversora de angiotensina na s?ndrome de pr?-ecl?mpsia

Submitted by Setor de Tratamento da Informa??o - BC/PUCRS ([email protected]) on 2015-05-28T11:40:36Z No. of bitstreams: 1 469525 - Texto Completo.pdf: 2925199 bytes, checksum: d0ce1f2f0c3cdc1d309d3f09e9a7d239 (MD5)Made available in DSpace on 2015-05-28T11:40:36Z (GMT). No. of bitstreams: 1 469525 - Texto Completo.pdf: 2925199 bytes, checksum: d0ce1f2f0c3cdc1d309d3f09e9a7d239 (MD5) Previous issue date: 2015-03-02Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPESIntroduction: Preeclampsia is a disease characterized as high maternal and fetal morbidity and mortality, diagnosed only after 20th gestational week, its etiology is not completely understood and healing is placental removal. It has been looking for biomarkers that allow early diagnosis for a better outcome of the disease. The 90 kDa isoform of Angiotensin Converting Enzyme (ACE), proposed as a new biomarker for hypertension, has not been studied in the preeclampsia syndrome so far. Objective: To evaluate the gene and protein expression, as well as enzymatic activity of ACE in pregnancy induced hypertension. Material and methods: It were included 69 normotensive and preeclampsia syndrome pregnant women at S?o Lucas Hospital/PUCRS, Porto Alegre/ RS- Brazil. Blood sample was collected to perform ACE genetic polymorphism, and three urine samples (during pregnancy, after delivery and at least 3 months after delivery) were taken to perform ACE protein polymorphism and enzymatic activity. This study was conducted through a partnership between Nephrology Service from PUCRS and Kidneys and Hormones from UNIFESP Laboratories research. Results: Scientific paper was published in Medical Hypotheses journal, entitled ?Angiotensin Converting Enzyme 90 kDa isoform: Biomarker for diagnosis of preeclampsia?? that described the hypotheses of this research. Comparing the participants clinical data among the groups (Normal pregnant, pure preeclampsia, superimposed preeclampsia), statistical significancy was observed between obstetric gestational age, blood pressure, newborn weight (p< 0.001) and placental weight (p= 0.030). Hypertension familial history compared with ACE genotypes (p= 0.017) suggests allele I involvement. Enzymatic activity ZPhe and Hhl ratio was different during the gestational period (p< 0.025), and also in relation to the ACE genotypes (p< 0.001). ZPhe and HhL isolated enzymatic activity also, in relation to the ACE genotypes, was not statistically different (p = 0.83 e p = 0.16, respectively). The protein polymorphism was not performed due to some technique problems, but this activity will be finished as soon as possible. Conclusion: It seems that allele I is associated with the hypertension familial history, and the genotypes that have this allele (ID, II) are predominantly present in pregnant women with preeclampsia. Enzymatic activity of Zphe/Hhl shows different behavior during the gestational period, and it also change according to genotypes classification. The data suggest that the mechanism involved in essential hypertension can be different from those involved in transient and spontaneous hypertension triggered pregnancy induced hypertension.Introdu??o: Pr?-ecl?mpsia ? uma doen?a de alta morbimortalidade materna e fetal, diagnosticada somente ap?s a 20? semana gestacional, de etiologia n?o totalmente esclarecida e a cura consiste na retirada da placenta. Segue-se na busca de biomarcadores que possibilitem um diagn?stico precoce para um melhor desfecho da doen?a. A isoforma 90 kDa da Enzima Conversora de Angiotensina (ECA), proposta como novo marcador de hipertens?o, ainda n?o foi estudada na s?ndrome de pr?-ecl?mpsia. Objetivos: Avaliar a express?o gen?tica, proteica e enzim?tica da ECA na Doen?a Hipertensiva Gestacional. Materiais e m?todos: Foram inclu?das 69 gestantes normotensas e com S?ndrome de Pr?-ecl?mpsia (Pr?-ecl?mpsia Pura ou Sobreposta) no Hospital S?o Lucas da PUCRS, Porto Alegre/ RS- Brasil. Foram coletadas uma amostra de sangue para realizar o polimorfismo gen?tico da ECA e 3 amostras de urina (durante a gesta??o, ap?s o parto e pelo 3 meses ap?s o parto) para realizar a an?lise do polimorfismo proteico e a atividade enzim?tica da ECA. Este estudo teve parceria entre os laborat?rios de pesquisa de Nefrologia da PUCRS e Rins e Horm?nios da UNIFESP. Resultados: Foi publicado um artigo cient?fico na revista Medical Hypotheses, intitulado em Angiotensin Converting Enzyme 90 kDa isoform: Biomarker for diagnosis of preeclampsia?, descrevendo a hip?tese desta pesquisa. Comparando os dados cl?nicos das participantes entre os grupos analisados (Gestante normal, Pr?- ecl?mpsia Pura e Pr?- eclampsia Sobreposta), houve signific?ncia estat?stica entre idade gestacional obst?trica, n?veis press?ricos, peso do rec?m-nascido (p<0,001) e peso da placenta (p= 0,030). A hist?ria familiar de hipertens?o comparada com os gen?tipos da ECA (p= 0,017) sugere envolvimento do alelo I. A raz?o da atividade enzim?tica de Zphe e Hhl foi diferente durante o per?odo gestacional (p<0,025) e tamb?m em rela??o aos gen?tipos da ECA (p<0,001). Enquanto que a atividade enzim?tica isolada de Zphe e Hhl em rela??o aos gen?tipos da ECA n?o foi significativa (p = 0,83 e p = 0,16, respectivamente). A an?lise do polimorfismo proteico n?o foi realizada devido a problemas na execu??o da t?cnica, mas essa atividade ser? conclu?da assim que poss?vel. Conclus?o: O alelo I parece estar associado com a hist?ria familiar de hipertens?o e os gen?tipos que possuem esse alelo (ID, II) est?o predominantemente mais presentes nas gestantes que apresentam pr?-ecl?mpsia. A atividade enzim?tica de ZPhe/Hhl apresenta comportamento diferente durante o per?odo gestacional e tamb?m se altera conforme a classifica??o genot?pica da gestante. Os dados sugerem que os mecanismos envolvidos na hipertens?o essencial possam ser diferentes dos envolvidos na hipertens?o transit?ria e espont?nea desencadeada nas Doen?as Hipertensivas Gestacionais

"Garota bonita": as representações sobre beleza e feminilidade na imprensa chapecoense

This monography intends to discuss the gender prescriptions represented in the press, highlighting the ideals of beauty and femininity as a social construction. The object of analysis was the column entitled Garota Bonita, published in the newspaper A voz de Chapecó during 1946, in the municipality of Chapecó, West of Santa Catarina. The speech present in the newspaper during the year 1946 served to understand the construction and representation of gender identity in the municipality, implied by the ideals of beauty and femininity, perceiving the frequent advertisements of beauty contests, medical advice, absences in textual speeches politicians and, mainly, the content of the column Garota Bonita, which disseminated models of behavior to women, advising on marriage, domestic life and social etiquette. The publications of the historian Tânia Regina de Luca contributed to the methodological development of this research, in dealing with journalistic sources. To support the investigation, the concept of gender was used as a category of historical analysis, as well as foundations of women's history. It was found in the analyzed discourse ideals of femininity that associated beauty with domestic work. The investigation made it possible to perceive changes in the ways of feeling, making love increasingly idealized and, with that, prescribing behaviors to fit in these romantic ideals. All these prescriptions of gender identity met with resistance, since it is understood that the column Garota Bonita existed because there was no social consensus on the place of women in society, to the point that Eugênio expressed dissatisfaction with women who fought for equal rights.Este trabalho discute as prescrições de gênero representadas na imprensa, evidenciando os ideais de beleza e feminilidade como construção social. O objeto de análise foi a coluna intitulada Garota Bonita, publicada no jornal A voz de Chapecó durante o ano de 1946, no município de Chapecó, Oeste de Santa Catarina. O discurso presente no jornal durante o ano de 1946 serviu para compreender a construção e representação da identidade de gênero no município, implicada pelos ideais de beleza e feminilidade, percebendo os frequentes anúncios de concursos de beleza, os conselhos médicos, as ausências nos discursos textuais políticos e, principalmente, o conteúdo da coluna Garota Bonita, que difundia modelos de comportamento às mulheres, aconselhando sobre o casamento, a vida doméstica e etiqueta social. As publicações da historiadora Tânia Regina de Luca auxiliaram para o desenvolvimento metodológico desta pesquisa, no trato com as fontes jornalísticas. Para fundamentar a investigação, utilizou-se o conceito de gênero enquanto categoria de análise histórica, assim como fundamentos da história das mulheres. Constatou-se no discurso analisado ideais de feminilidade que associavam beleza ao trabalho doméstico. A investigação permitiu perceber as mudanças nas formas de sentir, tornando o amor cada vez mais idealizado e com isso, prescrevendo comportamentos para caber nesses ideais românticos. Todas essas prescrições de identidade de gênero encontraram resistências, pois entende-se que a coluna Garota Bonita existiu por não haver consenso social sobre o lugar da mulher na sociedade, ao ponto que Eugênio manifestou descontentamento com mulheres que lutavam por igualdade de direitos

Angiotensin Converting Enzyme 90 kDa isoform: Biomarker for diagnosis of preeclampsia?

Preeclampsia (PE), one of the leading gestational hypertensive diseases, is characterized by increased blood pressure (>= 140/90 mm Hg) and pathological proteinuria after 20 weeks gestation. It is a complex, multifactorial syndrome with an unestablished etiology and cure. the search continues for a biomarker that could assist in the early prediction or diagnosis of PE, reducing the rate of maternal and fetal mortality. Based on the findings of Casarini et al. that suggest the 90 kDa isoform of the Angiotensin Converting Enzyme (ACE) as a possible marker of hypertension, we hypothesized that this isoform may be present in pregnant women with PE, since they present a transient and spontaneous model of systemic arterial hypertension in pregnancy.We believe, therefore, that pregnant women with pure PE (PPE) express the ACE 90 kDa isoform in urine, as well as having elevated isoform enzymatic activity, during pregnancy only. Postpartum, with the normalization of blood pressure, the protein isoform would no longer be expressed. Pregnant women with superimposed preeclampsia (SPE) would present the ACE 90 kDa isoform both during and after the gestation period, and its enzymatic activity would remain high as they are chronically hypertensive. It is expected that normotensive pregnant women do not present this isoform in their urine as elevated blood pressure levels do not occur. Both normotensive and PPE affected pregnant women with a family history of hypertension, will possibly express the ACE 90 kDa isoform before pregnancy and may become hypertensive, only after some years, through the influence of environmental factors and/or other diseases.If our hypothesis is confirmed, it will allow differentiation of PPE and SPE sooner than 12 weeks postpartum, which is currently the estimated period for confirmation of the specific diagnosis. Furthermore, it could be an early biomarker for predicting the disease, enabling the physician to choose the best clinical management. in addition, it would minimize the use of other methods as the biological sample for obtaining the marker is urine, a practical and effective test with good reproducibility. Finally, test results would enable a greater understanding of the mechanisms involved in gestational hypertension. (C) 2014 Elsevier B.V. All rights reserved.Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundacao de Amparo a Pesquisa do Rio Grande do Sul (FAPERGS)Pontificia Univ Catolica Rio Grande do Sul, Sao Lucas Hosp, Grad Program Med & Hlth Sci Nephrol, Sch Med,Inst Biomed Res, Porto Alegre, RS, BrazilUniversidade Federal de São Paulo, Escola Paulista Med, Dept Med, Div Nephrol, São Paulo, BrazilUniversidade Federal de São Paulo, Escola Paulista Med, Dept Med, Div Nephrol, São Paulo, BrazilWeb of Scienc

Increased levels of the soluble receptor of Interleukin-6 in patients with preeclampsia compared to normotensive pregnant women

AIMS: To compare Interleukin-6 soluble receptor (IL-6sR) plasmatic levels between normotensive pregnant controls and preeclamptic women. METHODS: Maternal blood samples were collected before delivery from 21 patients with preeclampsia and 39 normotensive pregnant controls. Samples were stored at -80°C until laboratory assay. IL-6sR was measured by ELISA enzyme immunoassay. To compare groups Student's t test was used. Results with P less than 0.05 were considered significant. RESULTS: Data from preeclampsia and normotensive pregnant controls were respectively: maternal age 22.3±4.8 vs 26.0±3.7 years (P=0.06); gestational age 32.7±5.8 vs 40.1±0.8 weeks (P=0.01); systolic blood pressure 143.0±2.2 vs 118.8±3.1 mmHg (P=0.01); diastolic blood pressure 112.5±4.0 vs 77.2±10.2 mmHg (P=0.01); uric acid 5.87±1.10 vs 4.57±0.12 mg/dL (P=0.02); creatinine 0.82±0.12 vs 0.73±0.09 mg/dL (P=0.01); birth weight 2130.7±839.3 vs 3555.0±261.0 g (P=0.01); placental weight 621.3±167.0 vs 796.3±154.2 g (P=0,05). Proteinuria over creatininuria ratio in the preeclampsia group was 2.40±1.31. The concentration of IL-6sR (ng/dL) was 28.7±10.8 in preeclampsia vs 16.5±6.4 in normotensive pregnant controls (P=0.01). CONCLUSIONS: These results show an increased plasma levels of IL-6sRin patients with preeclampsia compared to normotensive pregnant women. More studies are necessary to clarify the pathophysiology of this entity, including the analysis of other cytokines linked to this receptor, due to the fact that they can be the key for the systemic inflammatory response that occurs in these patients and therefore for their treatment