Calibration of the visible and near-infrared channels of the NOAA-9 AVHRR using high-altitude aircraft measurements from August 1985 and October 1986

Visible and near infrared wavelength sensors mounted on operational satellites now in use do not have onboard absolute calibration devices. One means of establishing an in-orbit calibration for a satellite sensor is to make simultaneous measurement of a bright, relatively uniform scene along the satellite view vector from a calibrated instrument on board a high altitude aircraft. Herein, aircraft data were recorded over White Sands, New Mexico at satellite overpass time. Comparison of the coincident aircraft and orbiting satellite data for the visible and near infrared wavelength channels of the NOAA-9 Advanced Very High Resolution Radiometer shows that the calibration of the visible channel was unchanged from prelaunch values, but that the near infrared channel has degraded 6 percent by Aug. 1985. By Oct. 1986 the visible channel had degraded 13 percent and the near infrared channel had degraded 19 percent

Visible and near-infrared channel calibration of the GOES-6 VISSR using high-altitude aircraft measurements

Present and future visible and near-infrared wavelength sensors mounted on operational satellites do not have on-board absolute calibration devices. One means of establishing an in-orbit calibration for a satellite sensor is to make simultaneous measurements of a bright, relatively uniform scene along the satellite view vector from a calibrated instrument on board a high altitude aircraft. Aircraft data were recorded over White Sands, New Mexico, and the coincident aircraft and orbiting satellite data is compared for the visible and near-infrared wavelength channel of the GOES-6 Visible Infrared Spin-Scan Radiometer

Calibration of the visible and near-infrared channels of the LANDSAT-5 Thematic Mapper using high-altitude aircraft measurements

Visible near-infrared sensors mounted on operational satellites now in use do not have on-board full aperture absolute calibration devices. One means of establishing an in-orbit calibration for a satellite sensor is to make simultaneous measurements of a bright, uniform scene along the satellite view vector from a calibrated instrument on board a high altitude aircraft. In the work reported here, aircraft data were recorded over White Sands, New Mexico at satellite overpass time for the LANDSAT-5 Thematic Mapper (TM). A comparison of the coincident aircraft and orbiting satellite data showed the radiometric gain for TM channel 1 had degraded 4.7 percent by August 28, 1985; gains for TM channels 2 and 3 were within 1 percent of prelaunch values

Schottky barrier heights at polar metal/semiconductor interfaces

Using a first-principle pseudopotential approach, we have investigated the Schottky barrier heights of abrupt Al/Ge, Al/GaAs, Al/AlAs, and Al/ZnSe (100) junctions, and their dependence on the semiconductor chemical composition and surface termination. A model based on linear-response theory is developed, which provides a simple, yet accurate description of the barrier-height variations with the chemical composition of the semiconductor. The larger barrier values found for the anion- than for the cation-terminated surfaces are explained in terms of the screened charge of the polar semiconductor surface and its image charge at the metal surface. Atomic scale computations show how the classical image charge concept, valid for charges placed at large distances from the metal, extends to distances shorter than the decay length of the metal-induced-gap states.Comment: REVTeX 4, 11 pages, 6 EPS figure

Social disconnectedness, loneliness, and mental health among adolescents in Danish high schools : a nationwide cross-sectional study

Background: Previous research has suggested that social disconnectedness experienced at school is linked to mental health problems, however, more research is needed to investigate (1) whether the accumulation of various types of social disconnectedness is associated with risk for mental health problems, and (2) whether loneliness is a mechanism that explains these associations. Methods: Using data from the Danish National Youth Study 2019 (UNG19), nation-wide cross-sectional data from 29,086 high school students in Denmark were analyzed to assess associations between social disconnectedness experienced at school (lack of classmate support, lack of teacher support, lack of class social cohesion, and not being part of the school community) and various mental health outcomes, as well as the mediating role of loneliness for each type of disconnectedness. Multilevel regression analyses were conducted to assess the associations. Results: Descriptive analyses suggest that 27.5% of Danish high school students experience at least one type of social disconnectedness at school. Each type of social disconnectedness was positively associated with mental health problems (depression symptoms, anxiety symptoms, stress, sleep problems, suicidal ideation, non-suicidal self-injury, eating disorder, body dissatisfaction, and low self-esteem) and negatively associated with mental well-being. In all cases, loneliness significantly mediated the associations. We found a clear dose-response pattern, where each addition in types of social disconnectedness was associated with (1) stronger negative coefficients with mental well-being and (2) stronger positive coefficients with mental health problems. Conclusion: Our results add to a large evidence-base suggesting that mental health problems among adolescents may be prevented by promoting social connectedness at school. More specifically, fostering social connectedness at school may prevent loneliness, which in turn may promote mental well-being and prevent mental health problems during the developmental stages of adolescence. It is important to note that focusing on single indicators of school social connectedness/disconnectedness would appear to be insufficient. Implications for practices within school settings to enhance social connectedness are discussed

Lower Limb Muscle Strength and Muscle Mass Are Associated With Incident Symptomatic Knee Osteoarthritis: A Longitudinal Cohort Study

Recent literature suggests that sarcopenia, often represented by low lower limbs muscle mass and strength, can be considered a potential risk factor for knee osteoarthritis (OA), but the available literature is still limited. We therefore aimed to investigate whether sarcopenia is associated with a higher risk of radiographic (ROA) and symptomatic knee OA (SxOA) in a large cohort of North American people in the context of the OA initiative. Sarcopenia at baseline was diagnosed in case of low skeletal muscle mass (i.e., lower skeletal mass index) and poor performance in the chair stands test. The outcomes of interest for this study included ROA (radiographical osteoarthritis) if a knee developed a Kellgren and Lawrence (KL) grade ≥2 at follow-up, and SxOA (symptomatic osteoarthritis) defined as new onset of a combination of painful knee OA. Altogether, 2,492 older participants (mean age: 68.4 years, 61.4% females) were included. At baseline, sarcopenia was present in 6.1% of the population. No significant difference in ROA prevalence was observed between those with and without sarcopenia (p=0.76), whilst people with sarcopenia reported a significant higher prevalence of SxOA (p<0.0001). Using a logistic regression analysis, adjusting for potential confounders at baseline and the diagnosis of sarcopenia during follow-up, sarcopenia was associated with a higher incidence of knee SxOA (odds ratio, OR=2.29; 95%CI [confidence interval]: 1.42-3.71; p=0.001), but not knee ROA (OR=1.48; 95%CI: 0.53-4.10; p=0.45). In conclusion, sarcopenia could be associated with a higher risk of negative knee OA outcomes, in particular symptomatic forms

Epigenetic Reprogramming in Naive CD4+ T Cells Favoring T Cell Activation and Nonâ Th1 Effector T Cell Immune Response as an Early Event in Lupus Flares

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/134183/1/art39720_am.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/134183/2/art39720.pd

Wnt5a Increases Cardiac Gene Expressions of Cultured Human Circulating Progenitor Cells via a PKC Delta Activation

Background: Wnt signaling controls the balance between stem cell proliferation and differentiation and body patterning throughout development. Previous data demonstrated that non-canonical Wnts (Wnt5a, Wnt11) increased cardiac gene expression of circulating endothelial progenitor cells (EPC) and bone marrow-derived stem cells cultured in vitro. Since previous studies suggested a contribution of the protein kinase C (PKC) family to the Wnt5a-induced signalling, we investigated which PKC isoforms are activated by non-canonical Wnt5a in human EPC. Methodology/Principal Findings: Immunoblot experiments demonstrated that Wnt5a selectively activated the novel PKC isoform, PKC delta, as evidenced by phosphorylation and translocation. In contrast, the classical Ca2+-dependent PKC isoforms, PKC alpha and beta2, and one of the other novel PKC isoforms, PKC epsilon, were not activated by Wnt5a. The PKC delta inhibitor rottlerin significantly blocked co-culture-induced cardiac differentiation in vitro, whereas inhibitors directed against the classical Ca2+-dependent PKC isoforms or a PKC epsilon-inhibitory peptide did not block cardiac differentiation. In accordance, EPC derived from PKC delta heterozygous mice exhibited a significant reduction of Wnt5a-induced cardiac gene expression compared to wild type mice derived EPC. Conclusions/Significance: These data indicate that Wnt5a enhances cardiac gene expressions of EPC via an activation of PKC delta