2,938 research outputs found
Research of Motivational Aspects for Marketing Support of Innovative Activity of Industrial Enterprises
The article is devoted to the theoretical grounding and development of practical recommendations for research and formation of motivational aspects for marketing support of innovative activity of industrial enterprises. Methodology of the research of marketing employees at industrial enterprises is revealed to clarify the motives of their behavior and the impact on existing businesses activity. Use of internal marketing is proposed to enhance the motivation of marketing employees for improving innovative activity of the enterprises. Application of motivational approach of the internal marketing is proved. This application is based on overcoming objections concerning innovation, study of internal incentives and opportunities for self-development and aims to result in a change and/or innovation, which is achieved through the formation of a balanced scorecard of marketing department, which is provides creation of preconditions to stimulate, support and development of innovation. Scientific and practical approaches are developed for the use of a balanced scorecard to determine sub-processes of marketing activities, as well as in assessing loyalty of the marketing employees
Регіональний туризм у Польській республіці в міжвоєнний період: Волинське воєводство (Regional Tourism in the Polish Republic in the Interbellum: Wołyń Voivodeship)
У дисертації досліджено зародження та розвиток туризму у Волинському воєводстві у міжвоєнний період. Зазначено, що активну участь у пропаганді туристичного руху брали державні органи влади та польські туристсько-краєзнавчі товариства й організації, використовуючи для цього різні форми та методи. Туризм був одним із методів колонізації та інтеграції українських земель у склад Польської республіки. Саме тому туристичному руху на цих землях приділялась особлива увага.
Встановлено, що у Волинському воєводстві на належному рівні функціонувала туристична інфраструктура. На основі наявних туристичних ресурсів та об’єктів здійснено класифікацію туризму на культурно-історичний, релігійний, лікувально-оздоровчий, шкільний та спортивний (The origins and the evolution of tourism in Wołyń Voivodeship in the interbellum is researched in the dissertation. It is mentioned that state institutions as well as Polish tourist and regional natural history societies and organizations used different methods in order to promote tourism which was one of the means of colonization and integration of the Ukrainian lands into the Polish Republic. This was the main reason why tourism was paid a significant attention to.
It is proved that Wołyń Voivodeship had a well established tourist infrastructure. Based on the available tourist resources and facilities, tourism has been classified as culture-historical, religious, health-related, educational and sport one
Saturation effect for dependence of the electrical conductivity of planar oriented nematic liquid crystal 6CB on the concentration of Cu7PS6 nanoparticles
The influence of Cu7PS6 nanoparticles with the average size 117 nm on the dielectric properties of planar oriented nematic liquid crystal 6CB has been investigated within the frequency range 10(1) ...10(6) Hz and at the temperature 293 K. It has been shown that when changing the concentration of nanoparticles within the range 0 to 1 wt.%, the conductivity of the liquid crystal changes stronger than its dielectric permittivity. It has been shown that the electrical conductivity increases monotonously with increasing the concentration of nanoparticles. However, for this dependence a saturation effect is observed. The mechanism of this effect was proposed.info:eu-repo/semantics/publishedVersio
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Crucial Role for Early Growth Response-1 in the Transcriptional Regulation of miR-20b in Breast Cancer
Transcriptional regulation of miRNAs that control the pathogenesis of breast cancer remains largely unknown. Here, we showed that ionizing radiation, a known breast carcinogen, triggered the differential expression of miR-20b in mammary tissues. We identified several GC-rich consensus binding motifs for the zinc finger transcription factor early growth response-1 (EGR1) in miR-20b promoter. miR-20b was upregulated by IR and its upregulation correlated with EGR1 expression in the breast cancer cell line HCC1806. Therefore, we used HCC1806 cells as a model system to explore the role of EGR1 in miR-20b transcription. siRNA knockdown of EGR1 attenuated miR-20b expression. Luciferase assays showed that whereas EGR1 stimulated luciferase activity driven by the wild-type miR-20b promoter, this induction was abolished in the mutant miR-20 promoter construct. We noted significant enrichment of EGR1 at miR-20b promoter in HCC1806 cells compared with normal human mammary epithelial cells. Suppression of miR-20b significantly inhibited HCC1806 cell proliferation and migration, and led to G 0/G 1 and S phase arrest. In vitro RNA-pull down assays indicated that miR-20b targets numerous tumor suppressors, including PTEN and BRCA1, which were downregulated in HCC1806. Conversely, suppression of miR-20b increased PTEN and BRCA1 levels. Moreover, immunohistochemical and FISH analyses showed that the miR-20b expression correlated significantly with EGR1 levels in breast cancer tissues. Our findings thus demonstrate for the first time that EGR1 is a key player in the transcriptional control of miR-20b, and miR-20b may in turn function as an oncogene by contributing to breast tumorigenesis via tumor suppressor targeting
Розвиток релігійного туризму на території Волинського воєводства у міжвоєнний період (Development of religious tourism on territory of Volyn province in an antimilitary period)
У статті висвітлено розвиток релігійного туризму на території Волинського воєводства у міжвоєнний період (In this article development of religious tourism is reɫected on territory
of the Volyn province in an antimilitary period
Tне dependence of excellent students’ skills from IQ and learning physics
In this paper the results of an intelligence quotient by students of 10th grade in school are presented. The concept of "excellent students’ skill" is introduced by authors. The results of IQ test are analyzed to estimate their intellectual abilities – That’s important to know when teaching physicsВ данной статье приводятся результаты теста для определения коэффициента интеллекта. Авторы вводят понятие «навыки отличника», анализируют результаты теста школьников 10-х классов на IQ, чтобы оценить их способность к интеллектуальной деятельности, что важно знать в процессе обучения физик
Організація туризму на території Волинського воєводства у міжвоєнний період (1921-1939) (Organization of tourism on territory of Volyn province in intermilitary period (1921–1939))
У статті проаналізовано особливості організації туристичної справи на території Волинського воєводства у міжвоєнний період (In this article activity of organization of tourist business on territory of the Volyn province in an intermilitary period are analysed
Formation of a brand of a higher education institution in the context of improving the quality of educational services
Волинське краєзнавче товариство і опіки над пам'ятками старовини та його внесок у розвиток туристичної справи на території Другої Речі Посполитої у міжвоєнний період (Volyn regional society and preservation of antiquity sights and its contribution into the development of tourist industry on the territory of the Second Rich Pospolyta during the intermilitary period)
У статті проаналізовано діяльність Волинського краєзнавчого товариства і опіки над пам’ятками старовини на території Другої Речі Посполитої, а також його внесок у розвиток туристичної галузі як на території Волині, так і Польської республіки (Volyn regional society and preservation of antiquity sights and its contribution into the development of tourist industry on the territory of the Second Rich Pospolyta during the intermilitary period
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