A timing optimization method based on clock skew scheduling and partitioning in a parallel computing environment

Paper presented at the Midwest Symposium on Circuits and Systems, San Juan, Puerto Rico.This paper describes the implementation of a heuristic method to perform non-zero clock skew scheduling of digital VLSI circuits in a parallel computing environment. In the proposed method, circuit partitions that have low number of timing paths between partitions are formed. Clock skew scheduling is applied independently to each partition-sequentially or in parallel on a computing cluster-and results are iteratively merged. The scalability of the proposed method is superior compared to conventional non-zero clock skew scheduling techniques due to the reduction of analyzed circuit sizes (partition sizes) at each iteration step and the potential to parallelize the analyses of these partitions. It is demonstrated that after only the first iteration step of the proposed method, feasible clock schedules for 65% of the ISCAS'89 benchmark circuits are computed. For these circuits, average speedups of 2.1X and 2.6X are observed for sequential and parallel application of clock skew scheduling to partitions, respectively

Nonlinear optical transformation of the polarization state of circularly polarized light with holographic-cut cubic crystals

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Timing-driven physical design for VLSI circuits using resonant rotary clocking

Paper presented at the Midwest Symposium on Circuits and Systems, San Juan, Puerto Rico.Resonant clocking technologies are next-generation clocking technologies that provide low or controllable-skew, low-jitter and multi-gigahertz frequency clock signals with low power consumption. This paper describes a collection of circuit partitioning, placement and synchronization methodologies that enables the implementation of high speed, low power circuits synchronized with the resonant rotary clocking technology. Resonant rotary clocking technology inherently supports (and requires) non-zero clock skew operation, which permits further improved circuit performances. The proposed physical design flow entails integrated circuit partitioning and placement methodologies that permit the hierarchical application of non-zero clock skew system timing. This design flow is shown to be a computationally efficient implementation method

Nonlinear mirror based on cross-polarized wave generation

We present a new type of nonlinear mirror based on the generation of a cross-polarized wave through a nonresonant electronic third-order process. It is characterized by a reflection coefficient that depends on the input intensity. Its behavior results from the interference between the nonlinearly generated cross-polarized wave and a /2 phase-retarded wave. This setup has a lot of advantages: it does not require any phase matching, it is achromatic and suitable for femtosecond pulses, linear losses are easily adjustable, and the overall behavior is predictable. The device has been experimentally tested using BaF 2 and YVO 4 crystals. OCIS codes: 190.0190, 230.4320, 140.4050. Nonlinear mirrors (NLMs) are known to be used for mode-locking (ML) operation in solid-state lasers and also for other applications, e.g., for pulse reshaping and compression and contrast improvement. In general, NLMs can be divided into two groups. The first group is based on ͑3͒ effects: self-induced ellipse rotation in isotropic media, 1,2 the Kerr lens effect, 3 or interference effects in an external cavity with ͑3͒ media. © 2006 Optical Society of America ͑2͒ cascaded processes. 12 Here, we introduce a new type of NLM based on the generation of a linearly polarized wave cross polarized to the input one. The cross-polarized wave (XPW) generation effect is a four-wave mixing process that depends on the anisotropy of the ͑3͒ tensor. The scheme of the XPW-based NLM is shown i

Comparative genomics of 16 Microbacterium spp. that tolerate multiple heavy metals and antibiotics

A total of 16 different strains of Microbacterium spp. were isolated from contaminated soil and enriched on the carcinogen, hexavalent chromium [Cr(VI)]. The majority of the isolates (11 of the 16) were able to tolerate concentrations (0.1 mM) of cobalt, cadmium, and nickel, in addition to Cr(VI) (0.5–20 mM). Interestingly, these bacteria were also able to tolerate three different antibiotics (ranges: ampicillin 0–16 μg ml−1, chloramphenicol 0–24 μg ml−1, and vancomycin 0–24 μg ml−1). To gain genetic insight into these tolerance pathways, the genomes of these isolates were assembled and annotated. The genomes of these isolates not only have some shared genes (core genome) but also have a large amount of variability. The genomes also contained an annotated Cr(VI) reductase (chrR) that could be related to Cr(VI) reduction. Further, various heavy metal tolerance (e.g., Co/Zn/Cd efflux system) and antibiotic resistance genes were identified, which provide insight into the isolates’ ability to tolerate metals and antibiotics. Overall, these isolates showed a wide range of tolerances to heavy metals and antibiotics and genetic diversity, which was likely required of this population to thrive in a contaminated environment

Processing of spatial-frequency altered faces in schizophrenia: Effects of illness phase and duration

Low spatial frequency (SF) processing has been shown to be impaired in people with schizophrenia, but it is not clear how this varies with clinical state or illness chronicity. We compared schizophrenia patients (SCZ, n534), first episode psychosis patients (FEP, n522), and healthy controls (CON, n535) on a gender/facial discrimination task. Images were either unaltered (broadband spatial frequency, BSF), or had high or low SF information removed (LSF and HSF conditions, respectively). The task was performed at hospital admission and discharge for patients, and at corresponding time points for controls. Groups were matched on visual acuity. At admission, compared to their BSF performance, each group was significantly worse with low SF stimuli, and most impaired with high SF stimuli. The level of impairment at each SF did not depend on group. At discharge, the SCZ group performed more poorly in the LSF condition than the other groups, and showed the greatest degree of performance decline collapsed over HSF and LSF conditions, although the latter finding was not significant when controlling for visual acuity. Performance did not change significantly over time for any group. HSF processing was strongly related to visual acuity at both time points for all groups. We conclude the following: 1) SF processing abilities in schizophrenia are relatively stable across clinical state; 2) face processing abnormalities in SCZ are not secondary to problems processing specific SFs, but are due to other known difficulties constructing visual representations from degraded information; and 3) the relationship between HSF processing and visual acuity, along with known SCZ- and medication-related acuity reductions, and the elimination of a SCZ-related impairment after controlling for visual acuity in this study, all raise the possibility that some prior findings of impaired perception in SCZ may be secondary to acuity reductions

Arbuscular mycorrhizal colonisation of roots of grass species differing in invasiveness

Recent research indicates that the soil microbial community, particularly arbuscular mycorrhizal fungi (AMF), can influence plant invasion in several ways. We tested if 1) invasive species are colonised by AMF to a lower degree than resident native species, and 2) AMF colonisation of native plants is lower in a community inhabited by an invasive species than in an uninvaded resident community. The two tests were run in semiarid temperate grasslands on grass (Poaceae) species, and the frequency and intensity of mycorrhizal colonisation, and the proportion of arbuscules and vesicles in plant roots have been measured. In the first test, grasses representing three classes of invasiveness were included: invasive species, resident species becoming abundant upon disturbance, and non-invasive native species. Each class contained one C3 and one C4 species. The AMF colonisation of the invasive Calamagrostis epigejos and Cynodon dactylon was consistently lower than that of the non-invasive native Chrysopogon gryllus and Bromus inermis, and contained fewer arbuscules than the post-disturbance dominant resident grasses Bothriochloa ischaemum and Brachypodium pinnatum. The C3 and C4 grasses behaved alike despite their displaced phenologies in these habitats. The second test compared AMF colonisation for sand grassland dominant grasses Festuca vaginata and Stipa borysthenica in stands invaded by either C. epigejos or C. dactylon, and in the uninvaded natural community. Resident grasses showed lower degree of AMF colonisation in the invaded stand compared to the uninvaded natural community with F. vaginata responding so to both invaders, while S. borysthenica responding to C. dactylon only. These results indicate that invasive grasses supposedly less reliant on AMF symbionts have the capacity of altering the soil mycorrhizal community in such a way that resident native species can establish a considerably reduced extent of the beneficial AMF associations, hence their growth, reproduction and ultimately abundance may decline. Accumulating evidence suggests that such indirect influences of invasive alien plants on resident native species mediated by AMF or other members of the soil biota is probably more the rule than the exception