Different regimes of Forster energy transfer between an epitaxial quantum well and a proximal monolayer of semiconductor nanocrystals

We calculate the rate of non-radiative, Forster-type energy transfer (ET) from an excited epitaxial quantum well (QW) to a proximal monolayer of semiconductor nanocrystal quantum dots (QDs). Different electron-hole configurations in the QW are considered as a function of temperature and excited electron-hole density. A comparison of the theoretically determined ET rate and QW radiative recombination rate shows that, depending on the specific conditions, the ET rate is comparable to or even greater than the radiative recombination rate. Such efficient Forster ET is promising for the implementation of ET-pumped, nanocrystal QD-based light emitting devices.Comment: 14 pages, 4 figure

Atypical presentations of malignant otitis externa

Abstract Introduction: Malignant otitis externa is a life-threatening infection of the skull base. Its presentation is not always typical. Case reports: We report three cases of malignant otitis externa which illustrate the diversity of its clinical manifestations and the difficulties in its diagnosis. Discussion: The perception of malignant otitis externa as an infection caused by Pseudomonas aeruginosa in diabetic patients is not always correct. The adoption of diagnostic criteria could be helpful in identifying atypical case

Temperature dependence of the magnetic anisotropy of metallic Y-Ba-Cu-O single crystals in the normal phase

The magnetic anisotropy measurements of metallic Y-Ba-Cu-O compounds in the normal phase reveal a temperature-dependent diamagnetic component of the susceptibility that increases with decreasing temperature. The temperature variation of the susceptibility anisotropy and its total change do not seem to be much affected by the presence of the superconductivity at some lower temperature and could not be accounted for by superconducting fluctuations. Rather, the data remind one of the behavior of some quasi-two-dimensional metals with anisotropic Fermi surfaces, reflecting the properties of the low-energy excitations in the normal phase. The anisotropy measurements above the bulk superconducting transition temperature Tc reveal the nonlinear effects, which are due to the onset of superconductivity in disconnected grains. The existence of a two-step transition, typical for granular superconductors, should be taken into consideration if the normal-phase susceptibility data are compared with the theoretical predictions in the vicinity of Tc

Dopamine perturbation of gene co-expression networks reveals differential response in schizophrenia for translational machinery.

The dopaminergic hypothesis of schizophrenia (SZ) postulates that positive symptoms of SZ, in particular psychosis, are due to disturbed neurotransmission via the dopamine (DA) receptor D2 (DRD2). However, DA is a reactive molecule that yields various oxidative species, and thus has important non-receptor-mediated effects, with empirical evidence of cellular toxicity and neurodegeneration. Here we examine non-receptor-mediated effects of DA on gene co-expression networks and its potential role in SZ pathology. Transcriptomic profiles were measured by RNA-seq in B-cell transformed lymphoblastoid cell lines from 514 SZ cases and 690 controls, both before and after exposure to DA ex vivo (100 μM). Gene co-expression modules were identified using Weighted Gene Co-expression Network Analysis for both baseline and DA-stimulated conditions, with each module characterized for biological function and tested for association with SZ status and SNPs from a genome-wide panel. We identified seven co-expression modules under baseline, of which six were preserved in DA-stimulated data. One module shows significantly increased association with SZ after DA perturbation (baseline: P = 0.023; DA-stimulated: P = 7.8 × 10-5; ΔAIC = -10.5) and is highly enriched for genes related to ribosomal proteins and translation (FDR = 4 × 10-141), mitochondrial oxidative phosphorylation, and neurodegeneration. SNP association testing revealed tentative QTLs underlying module co-expression, notably at FASTKD2 (top P = 2.8 × 10-6), a gene involved in mitochondrial translation. These results substantiate the role of translational machinery in SZ pathogenesis, providing insights into a possible dopaminergic mechanism disrupting mitochondrial function, and demonstrates the utility of disease-relevant functional perturbation in the study of complex genetic etiologies

Algorithm for obtaining the gradient expansion of the local density of states and the free energy of a superconductor

We present an efficient algorithm for obtaining the gauge-invariant gradient expansion of the local density of states and the free energy of a clean superconductor. Our method is based on a new mapping of the semiclassical linearized Gorkov equations onto a pseudo-Schroedinger equation for a three-component wave-function psi(x), where one component is directly related to the local density of states. Because psi(x) satisfies a linear equation of motion, successive terms in the gradient expansion can be obtained by simple linear iteration. Our method works equally well for real and complex order parameter, and in the presence of arbitrary external fields. We confirm a recent calculation of the fourth order correction to the free energy by Kosztin, Kos, Stone and Leggett [Phys. Rev. B 58, 9365 (1998)], who obtained a discrepancy with an earlier result by Tewordt [Z. Phys. 180, 385 (1964)]. We also give the fourth order correction to the local density of states, which has not been published before.Comment: 12 preprint pages, added remark concerning Eilenberger equation, accepted for publication in Phys. Rev.