TWO-POINT ANGULAR CORRELATION FUNCTION FOR THE GREEN BANK 4.85 GHZ SKY SURVEY

This paper presents an angular correlation analysis of the Green Bank 4.85 GHz radio catalog (Gregory \& Condon 1991) of 54,579 sources (S \gsim 25 mJy). The Green Bank catalog is found to be complete to S $\geq$ 35 mJy over 20$^{\circ} \leq \delta < 74^{\circ}$, 0$^h \leq \alpha < 24^h$, and Galactic latitude $|b| \geq 10^{\circ}$. The 2-point angular correlation function shows evidence for the clustering of radio sources, with a power-law distribution consistent with a slope $\gamma = -0.8$. This may well provide the $first$ detection of an angular correlation in a large area, complete deep radio survey.Comment: 14 pages, compressed, uuencoded postscript. Plots and text: anonymous ftp://charon.nmsu.edu/pub/PAPERS/aklypin, apj.uu and apjfigs.u

Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans

Genome-wide association studies (GWAS) have identified numerous common prostate cancer (PrCa) susceptibility loci. We have fine-mapped 64 GWAS regions known at the conclusion of the iCOGS study using large-scale genotyping and imputation in 25 723 PrCa cases and 26 274 controls of European ancestry. We detected evidence for multiple independent signals at 16 regions, 12 of which contained additional newly identified significant associations. A single signal comprising a spectrum of correlated variation was observed at 39 regions; 35 of which are now described by a novel more significantly associated lead SNP, while the originally reported variant remained as the lead SNP only in 4 regions. We also confirmed two association signals in Europeans that had been previously reported only in East-Asian GWAS. Based on statistical evidence and linkage disequilibrium (LD) structure, we have curated and narrowed down the list of the most likely candidate causal variants for each region. Functional annotation using data from ENCODE filtered for PrCa cell lines and eQTL analysis demonstrated significant enrichment for overlap with bio-features within this set. By incorporating the novel risk variants identified here alongside the refined data for existing association signals, we estimate that these loci now explain ∼38.9% of the familial relative risk of PrCa, an 8.9% improvement over the previously reported GWAS tag SNPs. This suggests that a significant fraction of the heritability of PrCa may have been hidden during the discovery phase of GWAS, in particular due to the presence of multiple independent signals within the same regio

School Networks and Sustainable Development

The promotion of new approaches to the development of knowledge and the production of education services, which respect the Europe 2020 strategies, is the precondition for the economic development of the entire country, upholding the principles of inclusion and sustainability. The scarcity of resources earmarked for the education system and the very complexity of learning needs suggest forms of institutional cooperation between schools and their stakeholders, which can only be achieved through networks of relationships. This article aims to highlight the conditions at the base of: the building and development of a network of relationships between the school and the community, so as to meet ever more complex educational needs; the maintenance and enhancement of relations in the network, with the aim of ensuring an effective system of educational services; the definition of responsibilities, structures and processes of school governance for the human capital’s growth as part of the sustainable development of a local community.