Quality control of educational process in the lyceum of medical profile when learning in distance mode during the COVID-19 pandemic

With the spread of the COVID-19 coronavirus infection pandemic and, as a result, the relevance of the transformation of curricula, many subjects of the education system have now switched to distance learning. Ukrainian Medical Lyceum of the National Medical University named after A.A. Bogomolets actively and successfully implements this format. The adaptation of the curriculum of the medical lyceum to the changed conditions takes into account the updated requirements. The study is devoted to the analysis of the perception of changes introduced by distance technologies in the educational process, and the possibilities of controlling its quality using the example of training in a medical lyceum. The collection of data for analysis was carried out using a questionnaire. In the course of the survey, which was answered by 187 respondents. The study examined in detail the advantages and disadvantages of learning on online platforms. It was concluded that new teaching methods require updated quality assessment methodologies, and that the greatest obvious benefit of online learning is adaptability and variability

Innovation development perspectives in a hotel industry by example of Radisson hotel chain in Ukraine

The article aims to show that the main and most important prerequisite for successful hotel business growth in current promptly changing business environment becomes development of innovation in the hotel industry. Though the term innovation is already widely defined by many researchers, it is considered in the article as a subject for future discussions leading to proposed scientific classification of innovations based on selected criterions. Evaluation of the process of innovation appearance in the hotel market allowed creation of the model, presenting the main influences and attributes of the whole innovation process in a hotel industry. Afterwards, the article discusses some specific innovation tools that are essential for hotel enterprises and which could be challenging for hoteliers in Ukrainian market nowadays. Based on the empirical research results, the obstacles which hinder up-to-date innovative operations in Ukrainian Radisson chain hospitality market are discussed. As well, concerning prospective innovation trends for Radisson Hotels in Ukraine, advices for future innovation implementation were proposed.KEY WORDS: innovation, hotel industry, innovations development.JEL CODES: D81, O31, O32, L83DOI: http://dx.doi.org/10.15181/rfds.v15i1.98

Medical university experiences regarding emergency remote teaching (ERT): Evidence from Ukraine

The study's main aim is to examine the opportunities and challenges of Emergency Remote Teaching (ERT), focusing on the students of O.O. Bogomolets National Medical University during COVID-19 pandemic. In order to conduct the study, an ex-post facto design of the quantitative research method was employed. Data were collected through a survey from 120 students and 15 teachers. For that, an instrument was developed to collect the responses related to face-to-face learning and online learning. The results reveal various technological, pedagogical, and social challenges. This study intends to examine the students' and teachers' experience of emergency remote teaching ERT in the wake of the COVID-19 Pandemic, especially Ukrainian university students. This study aims to know the advantages and disadvantages of online learning with individuals' demographics, interests, and satisfaction. This research assists in developing new techniques of education by focusing on the pros and cons of any methodology

Analysis of Physicochemical Natures of Modern Artifacts in MRI

Magnetic resonance imaging (MRI) is very useful in the medical sector as it uses radio waves and robust magnetic fields to produce images of the inside of the human body. MRIs are so helpful in pathologies. However, artifacts in MRI occur due to the complex nature of MRI. Artifacts in MRI may reduce the examination quality and may also be confused with pathology. Failing to identify artifacts in MRI can bring troubles. Hence, it’s very important to reduce or avoid artifacts in MRI. The major reasons behind artifacts in MRI are improper action of the MRI scanner, magnetic susceptibility, motion, chemical shifts, variation in signal intensity, etc. Due to MRI artifacts, patients can suffer from serious problems. Therefore, we have analyzed the physicochemical natures of artifacts in MRI. The research has made attempts to identify various types of artifacts in MRI and find out the causes of these artifacts. There have been samples of various types of artifacts based on which the analyses have been done. Based on these identifications of artifacts, there have also been discussions and analyses on how to avoid artifacts in MRI

Дослідження поліфенольного складу сировини дуба червоного (Quercus rubra L.)

The aim of the work was to determine the main groups of polyphenolic compounds in Quercus rubra L. raw materials. Materials and methods. The leaves and annual shoots of Northern Red Oak used for research were collected in August in Lisnyky village of Obuhiv district of Kyiv Oblast (Ukraine). Determination of the component composition and quantitative content of flavonoids (including separately catechins), hydroxycinnamic acids, and phenolic acids were carried out in the samples of air-shade-dried crushed raw material to a particle size of 3 mm by the method of high-performance liquid chromatography (HPLC). Agilent Technologies 1200 liquid chromatograph was used for liquid chromatography.Results. Using the HPLC method, 18 polyphenolic compounds were identified in leaves and annual shoots of Northern Red Oak, in particular, flavonoids: rutin, quercetin-3-β-glucoside, luteolin, neohesperidin; catechins: catechin, epicatechin, epicatechin gallate, gallocatechin; hydroxycinnamic acids: chlorogenic, caffeic, trans-ferulic, trans-cinnamic, p-coumaric, hydroxyphenylacetic, benzoic, syringic, sinapic acids; phenolic acid is gallic acid. The dominant component among flavonoids is rutin (323.43 mg/100 g) (in the composition of catechins, epicatechin gallate (25.45 mg/100 g) prevails); among hydroxycinnamic acids in Northern Red Oak raw materials, chlorogenic acid (139.62 mg/100 g) and sinapic acid (74.64 mg/100 g) prevail.Conclusions. The obtained results point to the prospects of further phytochemical and pharmacological studies of Quercus rubra raw materials, with the aim of creating new plant substances based on it with antioxidant, anti-inflammatory, and antiviral activityМета досліджень полягала у визначенні основних груп поліфенольних сполук у сировині Quercus rubra L. Матеріали і методи. Листя та однорічні пагони дуба червоного, що використовувались для досліджень, були зібрані у серпні 2020 р. у с. Лісники Обухівського району, Київської області (Україна). Визначення компонентного складу та кількісного вмісту флавоноїдів (у тому числі окремо – катехінів), гідроксикоричних кислот, фенольних кислот проводили у зразках висушеної повітряно-тіньовим шляхом та подрібненої до розміру часток 3 мм сировини методом високоефективної рідинної хроматографії (ВЕРХ). Рiдинну хроматографiю проведено на рiдинному хроматографi Agilent Technologies 1200. Результати. Методом ВЕРХ у листі та однорічних пагонах дуба червоного було ідентифіковано 18 сполук поліфенольної природи, зокрема, флавоноїди: рутин, кверцетин-3-β-глюкозиду, лютеолін, неогесперидин; катехіни: катехін, епікатехін, епікатехінгалат, галокатехін; гідроксикоричні кислоти: хлорогенова, кофейна, транс-ферулова, транс-цинамова, п-кумарова, гідроксифенілоцтова, бензойна, сирінгова, синапова кислоти; фенольна кислота – галова кислота. Домінуючим компонентом серед флавоноїдів є рутин (323,43 мг/100 г) (в складі катехінів переважає епікатехінгалат (25,45 мг/100г)), серед гідроксикоричних кислот у сировині дуба червоного переважають хлорогенова (139,62 мг/100г) та синапова (74,64 мг/100 г) кислоти. Висновки. Отримані результати вказують на перспективність подальших фітохімічних та фармакологічних досліджень сировини Quercus rubra L., з метою створення на її основі нових рослинних субстанцій з антиоксидантною, протизапальною, противірусною активніст

Evaluation of Virtual Reality Technology and Online Teaching System for Medical Students in Ukraine During COVID-19 Pandemic

A study has been conducted to evaluate the virtual reality technology and online teaching system among medical students of Bogomolets National Medical University, Ukraine during COVID-19 pandemic. The final questionnaire contained the 15 questions with 5 options to comprehensively evaluate the virtual reality technology and online teaching system. The feedback of the survey was analyzed to find effectiveness of virtual reality technology and online teaching in medical education in Ukraine. Data of survey reflected that mostly students adopted and agreed on virtual reality technology and online teaching and admitted that these technologies are best alternatives to physical learning with the 65.79% an agreement with the user-friendly interface for virtual reality and online teaching system, while, 64.03% showed an agreement that virtual reality and online teaching system compensated the suspension of face-to-face medical education during the COVID-19. During online learning, there was ample time for educational activities as depicted from their response of 36.84% as strongly agree, 35.96% as agree, 6.14% as disagree, 4.39% as strongly disagree and 16.67% as neither agree nor disagree. Tutors/teachers also enjoyed virtual reality and online learning through their experience and flexibility in time management. Likewise, the results of all questions showed positive reviews and encouraged virtual reality and online teaching in academic continuity and stability in medical education in Ukraine. It can be concluded that digital learning environments are extremely effective in terms of medical students and staff satisfaction, accomplishment, and technical learning skill growth

Novel (2-amino-4-arylimidazolyl)propanoic acids and pyrrolo[1,2-c]imidazoles via the domino reactions of 2-amino-4-arylimidazoles with carbonyl and methylene active compounds

The unexpectedly uncatalyzed reaction between 2-amino-4-arylimidazoles, aromatic aldehydes and Meldrum's acid has selectively led to the corresponding Knoevenagel-Michael adducts containing a free amino group in the imidazole fragment. The adducts derived from Meldrum's acid have been smoothly converted into 1,7-diaryl-3-amino-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-ones and 3-(2-amino-4-aryl-1H-imidazol-5-yl)-3-arylpropanoic acids. The interaction of 2-amino-4-arylimidazoles with aromatic aldehydes or isatins and acyclic methylene active compounds has led to the formation of pyrrolo[1,2-c]imidazole-6-carbonitriles, pyrrolo[1,2-с]imidazole-6-carboxylates and spiro[indoline-3,7'-pyrrolo[1,2-c]imidazoles], which can be considered as the analogues of both 3,3'-spirooxindole and 2-aminoimidazole marine sponge alkaloids.status: publishe

Novel (2-amino-4-arylimidazolyl)propanoic acids and pyrrolo[1,2-c]imidazoles via the domino reactions of 2-amino-4-arylimidazoles with carbonyl and methylene active compounds

The unexpectedly uncatalyzed reaction between 2-amino-4-arylimidazoles, aromatic aldehydes and Meldrum’s acid has selectively led to the corresponding Knoevenagel–Michael adducts containing a free amino group in the imidazole fragment. The adducts derived from Meldrum’s acid have been smoothly converted into 1,7-diaryl-3-amino-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-ones and 3-(2-amino-4-aryl-1H-imidazol-5-yl)-3-arylpropanoic acids. The interaction of 2-amino-4-arylimidazoles with aromatic aldehydes or isatins and acyclic methylene active compounds has led to the formation of pyrrolo[1,2-c]imidazole-6-carbonitriles, pyrrolo[1,2-с]imidazole-6-carboxylates and spiro[indoline-3,7'-pyrrolo[1,2-c]imidazoles], which can be considered as the analogues of both 3,3’-spirooxindole and 2-aminoimidazole marine sponge alkaloids