H.E.S.S. deeper observations on SNR RX J0852.0-4622

Supernova Remnants (SNRs) are believed to be acceleration sites of Galactic cosmic rays. Therefore, deep studies of these objects are instrumental for an understanding of the high energy processes in our Galaxy. RX J0852.0-4622, also known as Vela Junior, is one of the few (4) shell-type SNRs resolved at Very High Energies (VHE; E > 100 GeV). It is one of the largest known VHE sources (~ 1.0 deg radius) and its flux level is comparable to the flux level of the Crab Nebula in the same energy band. These characteristics allow for a detailed analysis, shedding further light on the high-energy processes taking place in the remnant. In this document we present further details on the spatial and spectral morphology derived with an extended data set. The analysis of the spectral morphology of the remnant is compatible with a constant power-law photon index of 2.11 +/- 0.05_stat +/- 0.20_syst from the whole SNR in the energy range from 0.5 TeV to 7 TeV. The analysis of the spatial morphology shows an enhanced emission towards the direction of the pulsar PSR J0855-4644, however as the pulsar is lying on the rim of the SNR, it is difficult to disentangle both contributions. Therefore, assuming a point source, the upper limit on the flux of the pulsar wind nebula (PWN) between 1 TeV and 10 TeV, is estimated to be ~ 2% of the Crab Nebula flux in the same energy range

HESS J1507-622: an unique unidentified source off the Galactic Plane

Galactic very high energy (VHE, > 100 GeV) gamma ray sources in the inner Galaxy H.E.S.S. survey tend to cluster within 1 degree in latitude around the Galactic plane. HESS J1507-622 instead is unique, since it is located at latitude of ~3.5 degrees. HESS J1507-622 is slightly extended over the PSF of the instrument and hence its Galactic origin is clear. The search for counterparts in other wavelength regimes (radio, infrared and X-rays) failed to show any plausible counterparts; and given its position off the Galactic plane and hence the absorption almost one order of magnitude lower, it is very surprising to not see any counterparts especially at X-rays wavelengths (by ROSAT, XMM Newton and Chandra). Its latitude implies that it is either rather close, within about 1 kpc, or is located well off the Galactic plane. And also the models reflect the uniqueness of this object: a leptonic PWN scenario would place this source due to its quite small extension to multi-kpc distance whereas a hadronic scenario would preferentially locate this object at distances of < 1 kpc where the density of target material is higher

Self-propelled particles with fluctuating speed and direction of motion

We study general aspects of active motion with fluctuations in the speed and the direction of motion in two dimensions. We consider the case in which fluctuations in the speed are not correlated to fluctuations in the direction of motion, and assume that both processes can be described by independent characteristic time-scales. We show the occurrence of a complex transient that can exhibit a series of alternating regimes of motion, for two different angular dynamics which correspond to persistent and directed random walks. We also show additive corrections to the diffusion coefficient. The characteristic time-scales are also exposed in the velocity autocorrelation, which is a sum of exponential forms.Comment: to appear in Phys. Rev. Let

H.E.S.S. observations of the Large Magellanic Cloud

The Large Magellanic Cloud (LMC) is a satellite galaxy of the Milky Way at a distance of approximately 48 kpc. Despite its distance it harbours several interesting targets for TeV gamma-ray observations. The composite supernova remnant N 157B/PSR J05367-6910 was discovered by H.E.S.S. being an emitter of very high energy (VHE) gamma-rays. It is the most distant pulsar wind nebula ever detected in VHE gamma-rays. Another very exciting target is SN 1987A, the remnant of the most recent supernova explosion that occurred in the neighbourhood of the Milky Way. Models for Cosmic Ray acceleration in this remnant predict gamma-ray emission at a level detectable by H.E.S.S. but this has not been detected so far. Fermi/LAT discovered diffuse high energy (HE) gamma-ray emission from the general direction of the massive star forming region 30 Doradus but no clear evidence for emission from either N 157B or SN 1987A has been published. The part of the LMC containing these objects has been observed regularly with the H.E.S.S. telescopes since 2003. With deep observations carried out in 2010 a very good exposure of this part of the sky has been obtained. The current status of the H.E.S.S. LMC observations is reported along with new results on N 157B and SN 1987A.Comment: 4 pages, 3 figures, proceedings of the 32nd Internatioal Cosmic Ray Conference, Beijing 201

Immunohistochemical Markers in the Assessment of Tumor Response

The examination of the possibility of using immunohistochemical and molecular (NCRT) and prognostic factors of the disease state. The study included 21 patients with locally advanced gastric cancer. All patients underwent the NCRT followed by gastrectomy D2. We analyzed the expression of HER2 / neu marker, Ki-67, p53, Cyklin D1, E-cadherin in biopsy (before therapy) and the operating material (after chemoradiotherapy and the treatment gap). We have found statistically significant decrease in the expression of Ki-67 markers and Cyklin D1, a trend towards to a decrease of p53 expression after the NCRT. The dynamics of expression of immunohistochemical markers examination is a promising approach in search for predictors of NCRT effectiveness for patients with locally advanced gastric cancer. Keywords: neoadjuvant chemoradiotherapy, immunohistochemical markers, molecular genetic markers, therapeutic pathomorphism, gastric cancer

Pulsar Wind Nebula candidates recently discovered by H.E.S.S

H.E.S.S. is currently the most sensitive instrument in the very-high-energy gamma-ray domain and has revealed many new sources along the Galactic Plane, a significant fraction of which seems to be associated with energetic pulsars. HESS J1825-137 and Vela X are considered to be the prototypes of such sources in which the large VHE nebula results from the whole history of the pulsar wind and the supernova remnant host, both evolving in a complex interstellar medium. These nebulae are seen to be offset from the pulsar position and, for HESS J1825-137, a spectral steepening at increasing distance from the pulsar has been measured. In this context, updated H.E.S.S. results on two previously published sources, namely HESS J1809-193 and HESS J1912+101, and preliminary results on the newly discovered HESS J1356-645, are presented. These extended VHE sources are thought to be associated with the energetic pulsars PSR J1809-1917, PSR J1913+1011 and PSR J1357-6429, respectively. Properties of each source in the VHE regime, together with those measured in the radio and X-ray domains, are discussed.Comment: 4 pages, 6 figures, Submitted to Proceedings of "4th Heidelberg International Symposium on High Energy Gamma-Ray Astronomy 2008