Historical Review of Ethnopharmacology in Karelia (1850s–2020s): Herbs and healers

Ethnopharmacological relevance: The traditional medicine of various peoples populating Russia is strongly underrepresented in the international anthropological literature. In addition, it has a multicomponent structure, a long history of relations with official medicine, and is still a living system with many people using folk remedies and visiting ritual specialists. Aim of the study: The article is a review of folk medicine in Karelia (north-west part of Russia) providing a short description of the history of medicine in this region and a comparison of folk medicine among Karelians and Russians. Materials and methods: The review analyzes and systematizes published and unpublished sources related to the main remedies used by the local populations – plants, animal products, minerals, etc. – from the 1850s–2000s, tracking the main tendencies in publications about the folk medicine of Karelians and Russians of Karelia. Results: A total of 104 medicinal plants belonging to 46 families were mentioned as medicinal. In total, they represented 386 uses which demonstrate the leading role of plant remedies in the folk medicine of Karelia. The plant species with the most uses were Betula sp., Plantago sp., Rubus idaeus, Viburnum opulus, Vaccinium vitis-idaea, and Daphne mezereum. Medicinal uses of other origins had more modest numbers: animal remedies included 146 uses, and mineral ones 43 uses. Among animal-based remedies, physiological discharges of the human body were the most popular; fish oil and bear body parts were the most used from the wild, while from the household various components of cows, horses, and dogs were used. Animal remedies were mostly used for healing furuncles, scrofula, frostbite, hernia, and lanugo. The most diversely used mineral remedy was salt. Conclusions: Karelians and Russians are very disproportionally represented in the literature due to the lack of interest in the folk medicine of Russians in Karelia, in contrast to that of Karelians. The disparity does not allow adequate comparison, but nonetheless the available data demonstrate that the remedies shared by both ethnic groups are quite few. The review also contributes to research on the relationship of folk medicine and various state institutions in Russia/the Soviet Union

JUSTIFICATION OF THE DIRECTIONS OF DEVELOPMENT OF THE ORGANIZATIONAL AND ECONOMIC MECHANISM OF BUSINESS MANAGEMENT OF MECHANICAL ENGINEERING

The concept and the main directions of methodology of development of the organizational and economic mechanism of business management of mechanical engineering on the basis of reserve and factorial approach is proved. Teoretiko-methodological approaches to ensuring effective functioning and a sustainable development of the enterprise are specified

JUSTIFICATION OF THE DIRECTIONS OF DEVELOPMENT OF THE ORGANIZATIONAL AND ECONOMIC MECHANISM OF BUSINESS MANAGEMENT OF MECHANICAL ENGINEERING

The concept and the main directions of methodology of development of the organizational and economic mechanism of business management of mechanical engineering on the basis of reserve and factorial approach is proved. Teoretiko-methodological approaches to ensuring effective functioning and a sustainable development of the enterprise are specified

Семинар «Политика национальных библиотек в области комплектования каждого отдельного национального документа в цифровой форме»

On the Workshop dedicated to the problems of Digital libraries «Policy of National Libraries in the field of Acquisition of each single National Document in a Digital form», held in the framework of the Program of exchanges between the Russian Federation and the Republic of Korea in Moscow on June 24, 2014 in the Center of Oriental Literature of the Russian State Library.О состоявшемся в рамках программы обмена специалистами между Россией и Республикой Кореей в Москве 24 июня 2014 г в Центре восточной литературы Российской государственной библиотеки (ЦВЛ РГБ) рабочем семинаре по проблемам цифровых библиотек «Политика национальных библиотек в области комплектования каждого отдельного национального документа в цифровой форме»

Desarrollo de la alfabetización intercultural de los docentes en el sistema de educación vocacional adicional

The general trends of contemporary education include the desire to integrate and universalize social relations. This study aims to explain that the process leads to the intensification of intercultural interaction between representatives of different cultural communities. The expansion of intercultural contacts in the modern world emphasizes the importance of achieving mutual understanding between people of different cultures. The study concludes that multicultural education should become an inseparable part of general education, including additional professional education, since interpersonal relationships take place in a multiethnic and multicultural environment.Las tendencias generales de la educación contemporánea incluyen el deseo de integrar y universalizar las relaciones sociales. Este estudio pretende explicar que el proceso conduce a la intensificación de la interacción intercultural entre representantes de diferentes comunidades culturales. La expansión de los contactos interculturales en el mundo moderno enfatiza la importancia de lograr el entendimiento mutuo entre personas de diferentes culturas. El estudio concluye que la educación multicultural debería convertirse en una parte inseparable de la educación general, incluida la e ucación profesional adicional, ya que las relaciones interpersonales tienen lugar en un entorno multiétnico y multicultural

The Mitochondria-Targeted Antioxidant SkQ1 Downregulates Aryl Hydrocarbon Receptor-Dependent Genes in the Retina of OXYS Rats with AMD-Like Retinopathy

The mitochondria-targeted antioxidant SkQ1 is a novel drug thought to retard development of age-related diseases. It has been shown that SkQ1 reduces clinical signs of retinopathy in senescence-accelerated OXYS rats, which are a known animal model of human age-related macular degeneration (AMD). The aim of this work was to test whether SkQ1 affects transcriptional activity of AhR (aryl hydrocarbon receptor) and Nrf2 (nuclear factor erythroid 2-related factor 2), which are considered as AMD-associated genes in the retina of OXYS and Wistar rats. Our results showed that only AhR and AhR-dependent genes were sensitive to SkQ1. Dietary supplementation with SkQ1 decreased the AhR mRNA level in both OXYS and Wistar rats. At baseline, the retinal Cyp1a1 mRNA level was lower in OXYS rats. SkQ1 supplementation decreased the Cyp1a1 mRNA level in Wistar rats, but this level remained unchanged in OXYS rats. Baseline Cyp1a2 and Cyp1b1 mRNA expression was stronger in OXYS than in Wistar rats. In the OXYS strain, Cyp1a2 and Cyp1b1 mRNA levels decreased as a result of SkQ1 supplementation. These data suggest that the Cyp1a2 and Cyp1b1 enzymes are involved in the pathogenesis of AMD-like retinopathy of OXYS rats and are possible therapeutic targets of SkQ1

Child’s heart development and contractility from prenatal to postnatal period

This literature review analyzes current data on the main stages of child’s heart contractility development from prenatal to postnatal period. The presented information will expand the conventional ideas on the age-related cardiovascular physiology in children, supplementing with relevant knowledge about the patterns of left ventricular mechanics, and the mechanisms affecting child’s heart morphology. In addition, we consider the evolutionary feasibility of the simultaneous existence of various left ventricular mechanics models, which ensure the effective cardiac function in the postnatal period. This is very important for the work of neonatologists, pediatricians, pediatric cardiologists and therapists

Coercion, violation of privacy and everyday difficulties as the cause of patient refusal treatment in psychiatric hospitals in Russia

Treatment in a psychiatric hospital is accompanied by a restriction of independence, violation of privacy, coercion, which causes displeasure of patients. The aim of the study was to verify the scale of everyday problems, violations of privacy and coercion in a psychiatric hospital to develop recommendations for the organization of a therapeutic environment. The study included 191 patients in a psychiatric hospital. Anonymous questionnaire was used. Statistical processing of the database was carried out by nonparametric method

Challenges in QCD matter physics - The Compressed Baryonic Matter experiment at FAIR

Substantial experimental and theoretical efforts worldwide are devoted to explore the phase diagram of strongly interacting matter. At LHC and top RHIC energies, QCD matter is studied at very high temperatures and nearly vanishing net-baryon densities. There is evidence that a Quark-Gluon-Plasma (QGP) was created at experiments at RHIC and LHC. The transition from the QGP back to the hadron gas is found to be a smooth cross over. For larger net-baryon densities and lower temperatures, it is expected that the QCD phase diagram exhibits a rich structure, such as a first-order phase transition between hadronic and partonic matter which terminates in a critical point, or exotic phases like quarkyonic matter. The discovery of these landmarks would be a breakthrough in our understanding of the strong interaction and is therefore in the focus of various high-energy heavy-ion research programs. The Compressed Baryonic Matter (CBM) experiment at FAIR will play a unique role in the exploration of the QCD phase diagram in the region of high net-baryon densities, because it is designed to run at unprecedented interaction rates. High-rate operation is the key prerequisite for high-precision measurements of multi-differential observables and of rare diagnostic probes which are sensitive to the dense phase of the nuclear fireball. The goal of the CBM experiment at SIS100 (sqrt(s_NN) = 2.7 - 4.9 GeV) is to discover fundamental properties of QCD matter: the phase structure at large baryon-chemical potentials (mu_B > 500 MeV), effects of chiral symmetry, and the equation-of-state at high density as it is expected to occur in the core of neutron stars. In this article, we review the motivation for and the physics programme of CBM, including activities before the start of data taking in 2022, in the context of the worldwide efforts to explore high-density QCD matter.Comment: 15 pages, 11 figures. Published in European Physical Journal