226 research outputs found
THE FUNCTION OF RELIGIOUS FAITH AND BELIEFS IN OBSESSIVE COMPULSIVE DISORDER
This paper is a review of the scientific literature regarding the topic of the function of religious faith and beliefs in Obsessive Compulsive Disorder (OCD). The mentioned papers are exploring a connection between religion and Obsessive-Compulsive Disorder (OCD) as well as religion’s influence in the development of OCD, and its effect on the treatment follow-ups. Moreover, it has been shown that there are both positive and negative effects considering scientific evidence and theoretical links about religion and mental health image in the general population. Extended research regarding OCD and religion is provided. Next, we attempt to make a division between religious faith (trust - πίστη - “how we believe”) and religious beliefs (the system regarding the symbol of faith - credo - “what we believe”) and consequently connect them with the already existing research papers additionally with feasible new topics of research
Studying, designing and 3d-printing an operational model of the Antikythera Mechanism
3D printing technology is an established industrial practice for rapid prototyping and manufacturing across a range of products, components and commercial sectors and at the same time possesses great potential for every-day life applications to be invented, explored and developed by the coming generations of scientists and engineers. A 3D printer installed in a school setting and complemented by well-designed educational activities can: stimulate the interest and curiosity of students; engage and motivate them into studying science, technology, engineering and mathematics (STEM) subjects, that they may choose or consider as career options; give the opportunity to teachers to achieve content and concept learning in an innovative way. In this paper we present an interdisciplinary science course that was developed for high school students and was implemented in an actual science classroom. The objectives of the course were both to spark the interest and creativity of students and teach them certain curriculum units the content knowledge of which is reached or utilized in an unconventional way. Students are gradually introduced into the 3D printing technology, its application and potential and are assigned a challenging collaborative project in which they have to study, analyse, design and build, using the 3D printer of their school, an operational model of a renown ancient artefact, the so-called Antikythera Mechanism. The mechanism is a 2100-year-old computer and is internationally known as an artefact of unprecedented human ingenuity and scientific, historic and symbolic value. The course involves the teaching of STEM curriculum domains of physics, astronomy, mathematics/geometry, informatics and technology related content and also non-STEM subjects like history and Greek language, both ancient and modern. We give an overview of the course, discuss its various phases and highlight its outcomes
Vacuum-Ultraviolet and Ultraviolet Fluorescence and Absorption Studies of Er(3+)-Doped Liluf4 Single-Crystals
Journal URL: http://apl.aip.org/apl/top.js
Answering SPARQL queries over databases under OWL 2 QL entailment regime
We present an extension of the ontology-based data access platform Ontop that supports answering SPARQL queries under the OWL 2 QL direct semantics entailment regime for data instances stored in relational databases. On the theoretical side, we show how any input SPARQL query, OWL 2 QL ontology and R2RML mappings can be rewritten to an equivalent SQL query solely over the data. On the practical side, we present initial experimental results demonstrating that by applying the Ontop technologies—the tree-witness query rewriting, T-mappings compiling R2RML mappings with ontology hierarchies, and T-mapping optimisations using SQL expressivity and database integrity
constraints—the system produces scalable SQL queries
Novel characterization techniques for cultural heritage using a TEM orientation imaging in combination with 3D precession diffraction tomography: a case study of green and white ancient Roman glass tesserae
We present new transmission electron microscopy (TEM) based electron diffraction characterization techniques (orientation imaging combined with 3D precession electron diffraction tomography-ADT) applied on cultural heritage materials. We have determined precisely unit cell parameters, crystal symmetry, atomic structure, and orientation/phase mapping of various pigment/opacifier crystallites at nm scale which are present in green and white Roman glass tesserae. Such TEM techniques can be an alternative to Synchrotron based techniques, and allow to distinguish accurately at nm scale between different crystal structures even in cases of same/very close chemical composition, where is also possible to visualize between different crystal orientations and amorphous/crystalline phases. This study additionally demonstrates that although opacifiers in green and white tesserae are found to have average Pb2Sb2O7 cubic and CaSb2O6 trigonal structures, their pyrochlore related framework can host many other elements like Cu, Ca, Fe through ionic exchanges at high firing temperatures which in turn may also contribute to the tesserae colour appearance
The Hellenic type of nondeletional hereditary persistence of fetal hemoglobin results from a novel mutation (g.-109G>T) in the HBG2 gene promoter
Nondeletional hereditary persistence of fetal hemoglobin (nd-HPFH), a rare hereditary condition resulting in elevated levels of fetal hemoglobin (Hb F) in adults, is associated with promoter mutations in the human fetal globin (HBG1 and HBG2) genes. In this paper, we report a novel type of nd-HPFH due to a HBG2 gene promoter mutation (HBG2:g.-109G>T). This mutation, located at the 3′ end of the HBG2 distal CCAAT box, was initially identified in an adult female subject of Central Greek origin and results in elevated Hb F levels (4.1%) and significantly increased Gγ-globin chain production (79.2%). Family studies and DNA analysis revealed that the HBG2:g.-109G>T mutation is also found in the family members in compound heterozygosity with the HBG2:g.-158C>T single nucleotide polymorphism or the silent HBB:g.-101C>T β-thalassemia mutation, resulting in the latter case in significantly elevated Hb F levels (14.3%). Electrophoretic mobility shift analysis revealed that the HBG2:g.-109G>T mutation abolishes a transcription factor binding site, consistent with previous observations using DNA footprinting analysis, suggesting that guanine at position HBG2/1:g.-109 is critical for NF-E3 binding. These data suggest that the HBG2:g-109G>T mutation has a functional role in increasing HBG2 transcription and is responsible for the HPFH phenotype observed in our index cases
Tiny Rare-Earth Fluoride Nanoparticles Activate Tumour Cell Growth via Electrical Polar Interactions
© 2018, The Author(s). Localised extracellular interactions between nanoparticles and transmembrane signal receptors may well activate cancer cell growth. Herein, tiny LaF3 and PrF3 nanoparticles in DMEM+FBS suspensions stimulated tumour cell growth in three different human cell lines (A549, SW837 and MCF7). Size distribution of nanoparticles, activation of AKT and ERK signalling pathways and viability tests pointed to mechanical stimulation of ligand adhesion binding sites of integrins and EGFR via a synergistic action of an ensemble of tiny size nanoparticles (< 10 nm). While tiny size nanoparticles may be well associated with the activation of EGFR, integrin interplay with nanoparticles remains a multifaceted issue. A theoretical motif shows that, within the requisite pN force scale, each ligand adhesion binding site can be activated by a tiny size dielectric nanoparticle via electrical dipole interaction. The size of the active nanoparticle stayed specified by the amount of the surface charges on the ligand adhesion binding site and the nanoparticle, and also by the separating distance between them. The polar component of the electrical dipole force remained inversely proportional to the second power of nanoparticle’s size, evincing that only tiny size dielectric nanoparticles might stimulate cancer cell growth via electrical dipole interactions. The work contributes towards recognising different cytoskeletal stressing modes of cancer cells
Vacuum-ultraviolet interconfigurational 4f3 → 4f 25d absorption and emission studies of the Nd3+ ion in KYF, YF, and YLF crystal hosts
The laser-induced vacuum-ultraviolet fluorescence spectra of KY 3F10:Nd3+ (KYF:Nd) and YF3:Nd 3+ (YF:Nd) single crystals pumped by a pulsed-discharge molecular F2 laser at 157 nm were obtained. A number of new fluorescence peaks were observed and were assigned to the 4f 25d → 4f3 dipole-allowed transitions of the Nd3+ ion. The absorption spectra of LiYF4:Nd3+ (YLF:Nd), KYF:Nd, and YF:Nd crystal samples in the vacuumultraviolet spectral regions were also obtained. Finally, the splitting of the states of the 4f25d configuration of the Nd 3+ ion, which is due to the crystal field, was observed in all the crystal samples. © 1995 Optical Society of America
VUV and UV fluorescence and absorption studies of tb3+ and tm3+ trivalent ions in liyf4 single crystal hosts
The laser induced fluorescence spectra of LiYF4: Tb3+ (YLF: Tb) and LiYF4:Tm3+ (YLF: Tm) single crystals, pumped by an F2 pulsed discharge molecular laser at 157 nm, were obtained in the vacuum ultraviolet (VUV) and ultraviolet (UV) regions of the spectrum, at room temperature. A number of new fluorescence peaks were observed for the first time. They were assigned to the dipole allowed transitions 4f75d→4f8 and 4f115d→4f12 of Tb3+ and Tm3+ ions respectively. The absorption spectra of the same crystal samples in the VUV and UV regions were taken as well. The edge (onset) and the energy of the states with 4fN-1 5d configuration were determined. © 1994 Taylor and Francis Ltd
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