A Corpus-Based Socio-Onomastic Analysis On Turkish And American Horror Film Naming

Both fear and horror have been extensively explored as universal unpleasant emotions with significant effects on psychological well-being. It is believed that horror is the feeling aroused when watching a horror film, and a sense of suspense and resolution is behind it. The present study explores how cultural, social, interactive, and cognitive contexts influence Turkish and American horror film naming. The present study aims to analyze Turkish and American horror film titles based on a socio-onomastic approach. So, 223 Turkish (1949-2021) and 2840 American (1898-2023) horror movie titles were investigated. The hypothesis was that Turkish horror film naming uses religious elements due to religious background. But according to the present study's findings, religious elements are also available in USA horror film naming. Yet, while making and naming their films, American horror film producers pay more attention to cultural events than Turkish filmmakers. On the other hand, the keywords used in naming Turkish and American horror films, regardless of their languages, were the same.

Crude Oil-polluted Soil Induces Ultrastructural and Enzyme Activity Changes in the Shoot of Lentil

Plants are always under threat due to various biotic and abiotic stresses. They respond to such threats by an efficient antioxidative enzyme system such as catalase. The presence of petroleum in soil is a stressful environmental factor for plants. In this study, cellular and biochemical changes were investigated in the shoot of lentil grown in the crude oil-polluted soil. Transmission electron microscope micrographs showed various injuries in the level of subcellular content including nucleus, chloroplast and mitochondria. In the treated samples, catalase activity and its kinetics factors (Vmax and Km) were different from the control. In the treated, Km of the enzyme was lower than that of the control. Temperature and pH profiles of the enzyme were different in the control and treated samples. Catalase purification in both treated and control samples showed that two catalase isoforms were expressed in the treated sample in comparison to the control, in which only one type of catalase was detected

Evaluation of apoptosis and angiogenesis in ectopic and eutopic stromal cells of patients with endometriosis compared to non-endometriotic controls

Background: Endometriosis is a chronic, painful, and inflammatory disease characterized by extra-uterine growth of endometrial tissues. Increased angiogenesis and resistance to apoptosis have been suggested to be involved in pathogenesis and development of endometriosis. The objective of this study was to examine apoptosis potential and angiogenesis contribution of eutopic (EuESCs) and ectopic (EESCs) endometrial stromal cells in patients with endometriosis compared to endometrial stromal cells from non-endometriotic controls (CESCs). Methods: Stromal cells were isolated by enzymatic digestion of ectopic (n = 11) and eutopic (n = 17) endometrial tissues from laparoscopically-confirmed endometriotic patients. Endometrial stromal cells of 15 non-endometriotic patients served as control. Following cell characterization by immunofluorescent staining and flow cytometry using a panel of antibodies, the total RNA was isolated from the cultured cells, and analyzed for the expression of genes involved in apoptosis (Bcl-2, Bcl-xL, Bax, and caspase-3) and angiogenesis vascular endothelial growth factor-A (VEGF-A) and hepatocyte growth factor (HGF) by Real-time PCR. Results: Significantly higher gene expression levels of Bcl-2 and Bcl-xL were found in EESCs compared with EuESCs and CESCs (p < 0.01). The gene expression of Bax in EESCs, EuESCs, and CESCs was not statistically significant. Furthermore, EuESCs exhibited a significantly lower caspase-3 gene expression compared with CESCs (p < 0.01) or EESCs (p < 0.05). Regarding angiogenesis, VEGF-A gene expression in EESCs (p < 0.001) and EuESCs (p < 0.05) were significantly higher compared with those of CESCs. EESCs exhibited a significantly higher HGF gene expression compared with EuESCs (p < 0.05). Conclusions: These findings suggest reduced propensity to apoptosis and increased angiogenesis potential of EESCs, which may be involved in pathogenesis of endometriosis. © 2020 The Author(s)

The effects of resveratrol treatment on Bcl-2 and bax gene expression in endometriotic compared with non-endometriotic stromal cells

Background: We aimed to examine resveratrol effects on gene expression of Bcl-2, Bax and Bcl-2/Bax ratio in endometrial stromal cells derived from women with and without endometriosis. Methods: Endometrial tissues were obtained from 40 endometriotic patients and 15 non-endometriotic controls undergoing laparoscopic surgery or hysterectomy in the gynecology ward of Rassoul Akram Hospital, Tehran, Iran from 2015 to 2017. After the enzymatic digestion, eutopic (EuESCs) and ectopic (EESCs) endometrial stromal cells from patients with endometriosis as well as endometrial stromal cells from non-endometriotic controls (CESCs) were treated with or without resveratrol (100 µM) and the levels of Bcl-2, Bax and Bcl-2/Bax gene expression ratio in the cells from all origins were examined at 6, 24 and 48 h post-treatment by real-time PCR. Results: Resveratrol treatment increased Bcl-2 expression in CESCs at 24 and 48 h and in EuESCs at 48 h (P<0.05), but had no significant effects on the expression of this gene in EESCs. On the other hand, resveratrol treatment increased Bax expression in EuESCs at 6 h and decreased its expression in EESCs at 48 h (P<0.05). Regarding the Bcl-2/Bax gene expression ratio, resveratrol treatment increased Bcl-2/Bax gene expression ratio in CESCs and EuESCs at 48 h (P<0.01). However, this treatment had no significant differential effect on Bcl-2 and Bcl-2/Bax gene expression ratio between CESCs and EuESCs at 48 h. Conclusion: Resveratrol treatment significantly increased Bcl-2/Bax gene expression ratio in EuESCs and CESCs but had no significant effect in EESCs. © 2020, Iranian Journal of Public Health. All rights reserved

Resveratrol treatment reduces expression of MCP-1, IL-6, IL-8 and RANTES in endometriotic stromal cells

Endometriosis is an inflammatory disease affecting reproductive-aged women. Immunologic disturbance, as well as inflammation, have crucial roles in the pathogenesis of endometriosis. In this study, we evaluated the effects of resveratrol treatment on expression of monocyte chemotactic protein-1 (MCP-1), interleukin-6 (IL-6), IL-8, and regulated upon activation, normal T cell expressed and secreted (RANTES) in endometrial stromal cells from patients with endometriosis compared with non-endometriotic controls. Thirteen eutopic (EuESCs) and nine ectopic (EESCs) endometrial stromal cells from endometriotic patients as well as eleven endometrial stromal cells from non-endometriotic controls (CESCs) were treated with resveratrol (100 μmol/L) or ethanol, and gene and/or protein expression of MCP-1, IL-6, IL-8 and RANTES was examined at 6, 24 and 48 hours following treatment in the cells from all origins. Resveratrol treatment significantly reduced gene and protein expression of MCP-1, IL-6, and IL-8 in EuESCs and EESCs compared with CESCs (P <.05-.001, P <.05-.001 and P <.05-<.01, respectively), and this reduction was more noticeable in EESCs than EuESCs (P <.05-<.001). Besides, resveratrol treatment significantly reduced RANTES protein expression in EESCs in all time intervals (P <.05). Resveratrol treatment significantly reduced the expression of MCP-1, IL-6, IL-8 and RANTES in EESCs. © 2020 The Authors. Journal of Cellular and Molecular Medicine published by Foundation for Cellular and Molecular Medicine and John Wiley & Sons Ltd

The effects of resveratrol on the expression of VEGF, TGF-β, and MMP-9 in endometrial stromal cells of women with endometriosis

Resveratrol is a phytochemical with anti-angiogenic, anti-inflammatory, and antioxidant properties. The present study has evaluated the effect of resveratrol on the expression of vascular endothelial growth factor (VEGF), transforming growth factor-β (TGF-β) and matrix metalloproteinase-9 (MMP-9) as factors related to endometriosis progression. Thirteen eutopic (EuESCs) and 8 ectopic (EESCs) endometrial stromal cells from women with endometriosis and 11 control endometrial stromal cells (CESCs) were treated with resveratrol (100 µM) for 6, 24 and 48 h. The gene and protein expression levels of VEGF, TGF-β, and MMP-9 were measured using real-time PCR and ELISA methods, respectively. Results showed that the basal gene and protein expression of VEGF and MMP-9 were higher in EESCs compared to EuESCs and CESCs (P < 0.01 to < 0.001 and P < 0.05 to < 0.01 respectively). Also, resveratrol treatment decreased the gene and protein expression of VEGF and MMP-9 in EuESCs, EESCs and CESCs (P < 0.05 to < 0.01 and P < 0.05 to < 0.01 respectively) and gene and protein expression of TGF-β in EESCs and EuESCs (P < 0.05 to < 0.01). The effect of resveratrol in reduction of VEGF gene expression was statistically more noticeable in EESCs compared to EuESCs and CESCs (P < 0.05). According to the findings, resveratrol may ameliorate endometriosis progression through reducing the expression of VEGF, TGF-β, and MMP-9 in endometrial stromal cells (ESCs). © 2021, The Author(s)

Effect of fish oil on circulating asymmetric dimethylarginine and adiponectin in overweight or obese patients with atrial fibrillation

Obesity and adipose-derived peptides might be involved in the pathogenesis of atrial fibrillation (AF). Adiponectin plays a major role in the modulation of several metabolic pathways, and asymmetric dimethylarginine (ADMA) has been suggested to be predictive of AF and associated adverse events. The aim of this study was to investigate the effect of fish oil supplementation on circulating adiponectin and ADMA in overweight or obese patients with persistent AF. In this randomized, double-blind, placebo-controlled trial, 80 overweight or obese (body mass index (BMI) � 25 kg/m2) patients with persistent AF were randomly assigned to two groups to receive either 2 g/day fish oil or placebo, for 8 weeks. Serum levels of adiponectin and ADMA, and anthropometric indexes were measured. This study showed that serum adiponectin concentrations increased significantly following fish oil supplementation compared with the placebo group (13.15 ± 7.33 vs. 11.88 ± 6.94 µg/ml; p =.026). A significant reduction was also observed in serum ADMA levels in the fish oil compared with the placebo group following the intervention (0.6 ± 0.13 vs. 0.72 ± 0.15 µmol/L; p =.001). The changes in serum adiponectin and ADMA concentrations remained significant after adjustments for baseline values, age, sex, and changes of BMI and waist circumference (p =.011 and p =.001, respectively). In conclusion, 8 weeks supplementation with fish oil increased serum adiponectin and decreased ADMA concentrations in overweight or obese patients with persistent AF. As adiponectin and ADMA are suggested to be involved in many pathways associated with AF, the current findings might be promising in the clinical management of this disease, an issue that needs further investigations. © 2020 The Authors. Food Science & Nutrition published by Wiley Periodicals, Inc

Ruminant trans-fatty acids and risk of breast cancer: A systematic review and meta-analysis of observational studies

INTRODUCTION: Ruminant trans-fatty acids, especially cis9, trans11-conjugated linoleic acid (c9, t11-CLA) and trans11-18:1 vaccenic acid (t11-18:1 VA) appear to have anticarcinogenic activity against breast cancer in animal and in vitro experiments. However, the results remain inconsistent. We therefore conducted a systematic review and metaanalysis to assess the association of c9, t11-CLA, and t11-18:1 VA (intake or serum levels) with breast cancer risk. EVIDENCE ACQUISITION: Relevant studies were identified by a search of PubMed, OVID, SCOPUS and Google scholar databases through 25 May 2015. We included case-control and cohort studies that reported relative risk (RR) estimates with 95 confidence intervals (CIs) for the association between c9, t11-CLA and t11-18:1 VA intake or their serum levels and the risk of breast cancer. This meta-analysis was conducted according to the guidelines for the meta-analysis of observational studies in epidemiology. EVIDENCE SYNTHESIS: Three studies on c9, t11-CLA and t11-18:1 VA serum levels and t11-18:1 VA intake were evaluated in the systematic review only (narrative synthesis) and four studies (2 case-control and 2 cohort studies on c9, t11-CLA intake) were included in the meta-analysis (quantitative synthesis). The pooled RR for the highest vs lowest category of c9, t11-CLA intake was 0.94 (95 CI: 0.64-1.25) with evidence of heterogeneity (with 67, 533 participants, I2=78.3, P=0.003). Studies that could not be included in the quantitative syntheses were inconclusive. CONCLUSIONS: No association was found between c9, t11-CLA intake and breast cancer risk, but the number of studies identified was small. © 2016 Edizioni Minerva Medica

DIJAHRONA ANALIZA EKOLOŠKOG DISKURSA U IMDb

Media is a useful tool to convey various types of messages. Within the past years, broadcasting media has covered a wide range of different communication methods such as television, radio, newspapers, and magazines. The article's central hypothesis is that movies, TV, and video games quotes, as the subcategory of broadcasting, convey messages about environmental issues. It seems that ecological discourse analysis can be useful, as it focuses on texts about the environment. In a diachronic approach, the present article aims to explore the environmental issues in movies, TV, and video games quotes; in this regard, we analyzed ecological discourse and solutions proposed by IMDb quotes. The data was collected from the IMDb database using Keyword in Context (KWIC) over 1990-2020. The findings indicated that KWICs such as global warming (38%) and endangered species (19.18%) had the highest frequencies. On the other hand, only 0.67% of the raw numbers of quotes belonged to environmental issues, which indicated that IMDb quotes implicitly conveyed the message regarding ecological matters. Furthermore, the studied IMDb mostly explained the consequences and provided solutions to environmental issues. Therefore, the frequency of informing people about environmental negligence was much lower than expected.Mediji su korisno sredstvo za prenošenje različitih poruka. Tokom proteklih godina, elektronski mediji su obuhvatili širok spektar različitih metoda komunikacij,e kao što su televizija, radio, novine i časopisi. Centralna hipoteza članka je da filmovi, TV i video igrice, kao mediji emitovanja poruka, prenose poruke o pitanjima životne sredine. Čini se da analiza ekološkog diskursa može biti korisna, jer se fokusira na tekstove o životnoj sredini. U dijahronom pristupu, ovaj članak ima za cilј da istraži pitanja životne sredine u filmovima, TV emisijama i video igarama; s tim u vezi, analizirali smo ekološki diskurs i rešenja koja predlažu IMDb citati. Podaci su prikuplјeni iz IMDb baze podataka pomoću softvera KWIC tokom 1990–2020. Podaci su pokazali da KWIC kao što su globalno zagrevanje (38%) i ugrožene vrste (19,18%) imaju najveću učestalost. S druge strane, samo 0,67% broja citata pripada pitanjima životne sredine, što ukazuje da IMDb citati implicitno prenose poruku u vezi sa životnom sredinom. Štaviše, proučavani uzorak je uglavnom objašnjavao posledice i rešenja za pitanja zaštite životne sredine. Zbog toga je učestalost obaveštavanja lјudi o nemaru pri očuvanju sredine bila mnogo manja od očekivane