GPS Data Processing Software

Práce se zabývá návrhem a implementací aplikace pro zpracování údajů o prošlých trasách ve formátu GPX. Aplikace zobrazuje trasu na mapových podkladech, umožňuje její editaci, pojmenování trasových bodů a přiřazení fotografií. O trase poskytuje řadu statistických údajů včetně grafů výškového a rychlostního profilu. Aplikace také nabízí možnost sestavit a vygenerovat prezentaci obsahující fotografie a snímky mapy. Teoretická část práce pojednává o systému GPS, způsobu záznamu trasy, o mapových podkladech a o návrhu aplikace. Cílem praktické části je pak navržené řešení implementovat a otestovat.The aim of the thesis is to suggest and implement an application for processing data about absolved tracks in GPX format. The application displays tracks on map layers, offering the possibility of editing the tracks, naming points on the tracks and adding photographs. A whole scale of statistic data is available for each track, including elevation and speed profile graph. Moreover, the application enables users to prepare and generate a presentation including photographs and map screenshots. The theoretical part of the thesis deals with GPS navigation system, ways of recording routes (tracks), map data and application suggestion. The aim of the practical part is to implement the suggested solution and test it.

Cyanobacteria and microcystin contamination in untreated and treated drinking water in Ghana

© 2017, Page Press Publications. All rights reserved. Although cyanobacterial blooms and cyanotoxins represent a worldwide-occurring phenomenon, there are large differences among different countries in cyanotoxin-related human health risk assessment, management practices and policies. While national standards, guideline values and detailed regulatory frameworks for effective management of cyanotoxin risks have been implemented in many in­dustrialized countries, the extent of cyanobacteria occurrence and cyanotoxin contamination in certain geographical regions is underreported and not very well understood. Such regions include major parts of tropical West and Central Africa, a region constisting of more than 25 countries occupying an area of 12 million km2, with a total population of 500 milion people. Only few studies focusing on cyanotoxin occurrence in this region have been published so far, and reports dealing specifically with cyanotoxin contamination in drinking water are extremely scarce. In this study, we report seasonal data on cyanobactcria and microcystin (MC) contamination in drinking water reservoirs and adjacent treatment plants located in Ghana, West Africa. During January-June 2005, concentrations of MCs were monitored in four treatment plants supplying drinking water to major metropolitan areas in Ghana: the treatment plants Barekese and Owabi, which serve Kumasi Metropolitan Area, and the plants Kpong and Weija, providing water for Accra-Tema Metropolitan Area. HPLC analyses showed that 65% samples of raw water at the intake of the treatment plants contained intracellular MCs (maximal detected concentration was 8.73 fig L-1), whereas dissolved toxins were detected in 33% of the samples. Significant reduction of cyanobacterial cell counts and MC concentrations was achieved during the entire monitoring period by the applied conventional water treatment methods (alum flocculation, sedimentation, rapid sand filtration and chlorination), and MC concentration in the final treated water never exceeded 1 fig L-1 (WHO guideline limit for MC-LR in drinking water). However, cyanobacterial cells (93-3,055 cell mL-1) were frequently found in the final treated water and intracellular MCs were detected in 17% of the samples (maximal concentration 0.61 (μg L-1), while dissolved MCs were present in 14% of the final treated water samples (maximal concentration 0.81 μg L-1). It indicates a borderline efficiency of the water treatment, thus MC concentrations in drinking water might exceed the WHO guideline limit if the treatment efficiency gets compromised. In addition, MC concentrations found in the raw water might represent significant human health risks for people living in areas with only a limited access to the treated or underground drinking water

Personal care product use and lifestyle affect phthalate and DINCH metabolite levels in teenagers and young adults

Humans are widely exposed to phthalates and their novel substitutes, and considering the negative health effects associated with some phthalates, it is crucial to understand population levels and exposure determinants. This study is focused on 300 urine samples from teenagers (aged 12-17) and 300 from young adults (aged 18-37) living in Czechia collected in 2019 and 2020 to assess 17 plasticizer metabolites as biomarkers of exposure. We identified widespread phthalate exposure in the study population. The diethyl phthalate metabolite monoethyl phthalate (MEP) and three di (2-ethylhexyl) phthalate metabolites were detected in the urine of >99% of study participants. The highest median concentrations were found for metabolites of low-molecular-weight (LMW) phthalates: mono-n-butyl phthalate (MnBP), monoisobutyl phthalate (MiBP) and MEP (60.7; 52.6 and 17.6 μg/L in young adults). 1,2-cyclohexanedicarboxylic acid diisononyl ester (DINCH) metabolites were present in 68.2% of the samples with a median of 1.24 μg/L for both cohorts. Concentrations of MnBP and MiBP were similar to other European populations, but 5-6 times higher than in populations in North America. We also observed large variability in phthalate exposures within the study population, with 2-3 orders of magnitude differences in urinary metabolites between high and low exposed individuals. The concentrations varied with season, gender, age, and lifestyle factors. A relationship was found between high levels of MEP and high overall use of personal care products (PCPs). Cluster analysis suggested that phthalate exposures depend on season and multiple lifestyle factors, like time spent indoors and use of PCPs, which combine to lead to the observed widespread presence of phthalate metabolites in both study populations. Participants who spent more time indoors, particularly noticeably during colder months, had higher levels of high-molecular weight phthalate metabolites, whereas participants with higher PCP use, particularly women, tended to have higher concentration of LMW phthalate metabolites.Authors thank the Research Infrastructure RECETOX RI (No. LM2018121) and CETOCOEN EXCELLENCE (CZ.02.1.01/0.0/0.0/17_043/0009632) for a supportive background. The work was supported by the Operational Programme Research, Development and Innovation – project Cetocoen Plus (CZ.02.1.01/0.0/0.0/15_003/0000469) and the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 857560. This study has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 733032. We thank all collaborating field workers, laboratory and administrative personnel, and especially the cohort participants who invested their time and provided samples and information for this study. This study reflects only the authors’ view and the European Commission is not responsible for any use that may be made of the information it contains.S

Strategic analysis of the beer market in Czech Republic

The bachelor work focuses on strategic analysis of Plzeňský prazdroj Inc. and on analysis of beer market in Czech Republic. Headquarter of Plzeňský prazdroj Inc. is located in Plzen and it is part of major companies on the beer market. Aim of work is to present possibilities of strategic analysis which is the first step of the business valuation based on income analysis. Strategic analysis consists of free parts. The content of the first part is rating of the beer market and forecasting of the whole beer market sales. The content of the second part is comparison of company with other competitors on the beer market. Finally the last part is the forecasting of Plzeňský prazdroj Inc. sales

Size premium for purposes of income approach valuation in the Czech Republic

Diplomová práce se zabývá použitím prémie za velikost při výnosovém ocenění podniku v České republice. Prémie za velikost je součástí modelu CAPM při stanovení nákladů na vlastní kapitál. Existují empirické studie, které se prémií za velikost zabývají. Tyto studie jsou vypracovány na základě dat z amerického kapitálového trhu. Při stanovení nákladů na vlastní kapitál v České republice musí znalec pro stanovení prémie za velikost použít výsledky těchto studií. Problémem je, že z hlediska velikosti jednotlivých společností je český a americký trh nesrovnatelný. To vede k situaci, kdy většina českých podniků patří podle studií z amerického kapitálového trhu do stejné (nejmenší) velikostní kategorie. Při použití takového postupu je přiřazována všem společnostem v České republice stejná prémie za velikost. Diplomová práce se nejdříve zaměřuje na teoretický základ modelu CAPM a prémie za velikost. V další části je analyzován stávající přístup v české praxi. Hlavní částí diplomové práce je pokus o odhad prémie za velikost pro region Evropy, Střední Evropy a ČR společně se SR. Závěr práce obsahuje doporučení pro stanovení prémie za velikost společnosti ve výnosovém ocenění podniků v České republice.The diploma thesis deals with application of size premium for purposes of income approach when value of company in Czech Republic is estimated. The size premium is the part of CAPM model when cost of equity is estimated. There are empirical studies which deal with the size premium. These studies are based on data from the US capital market. An expert in Czech Republic has to use the results of size premium from these studies when he estimates cost of equity. The issue is that size of Czech companies is in comparison with size of US companies very different. When the size premium is estimated, the most of Czech companies belongs in the same (the lowest) size category. When we use this approach the most of companies got the same size premium. At first the diploma thesis focuses on theory concerning to CAPM model and size premium. Current approach in Czech Republic is analyzed in further part of the thesis. The major part of the thesis contains attempt to estimate the size premium for Europe, Central Europe and Czech Republic together with Slovakia region. The summary of the thesis contains recommendations for situation when the size premium is estimated for purposes of income approach valuation in Czech Republic

The use of minimization and conservation tillage technologies in order to reduce water erosion on cultivated lands

The main objective of this methodology is to present the latest knowledge on protection of agricultural lands from water erosion to wide professional agricultural public with respect to its degradation effect on soil and long-term remedy of damage caused. It should also be appealing to responsible and consistent use of soil erosion control measures, because ensuring the sustainability of soil fertility not only for the present generation but for the future should be an effort for both professionals and also the general public. And just choose a convenient methods of agricultural land management, use of soil tillage technologies that prevent water erosion runoff and support rainfall water infiltration into the soil are being the right way to achieve that goal

Region specifický přístup v analýze ekologických rizik - metodika hodnoceni ve vztahu k přírodním katastrofám:Projekt IDRIS II. Hodnocení ekologických rizik

Region specifický přístup jako metodika využívající data dostupná z biomonitoringu pro hodnocení vlivu plošně působících ekologických katastrof. Praktické možnosti bioindikace pro hodnocení vlivu přírodních katastrof v různých ekosystémech. Možnosti vypracování "krizových" plánů pro hodnocení ekologických rizik pro území potenciálně zasažitelná povodněmi a vypracování region specifické strategie bioindikace a hodnocení rizik. Vypracování strategie pro indikaci expozice a účinku známých i dosud málo sledovaných skupin polutantů v průběhu katastrof typu povodní - současná aplikace chemických, toxikologických a molekulárně biologických metod. Koncepční dopracování metodiky hodnocení ekologických rizik postihující vliv na biologické systémy od molekulární a buněčné úrovně až po úroveň ekosystémů. Prezentace EcoRA

Firefighters and the liver: Exposure to PFAS and PAHs in relation to liver function and serum lipids (CELSPAC-FIREexpo study)

Introduction: Firefighting is one of the most hazardous occupations due to exposure to per- and polyfluoroalkyl substances (PFAS) and polycyclic aromatic hydrocarbons (PAHs). Such exposure is suspected to affect the cardiometabolic profile, e.g., liver function and serum lipids. However, only a few studies have investigated the impact of this specific exposure among firefighters. Methods: Men included in the CELSPAC-FIREexpo study were professional firefighters (n = 52), newly recruited firefighters in training (n = 58), and controls (n = 54). They completed exposure questionnaires and provided 1-3 samples of urine and blood during the 11-week study period to allow assessment of their exposure to PFAS (6 compounds) and PAHs (6 compounds), and to determine biomarkers of liver function (alanine aminotransferase (ALT), gamma-glutamyl transferase (GGT), aspartate aminotransferase (AST), alkaline phosphatase (ALP) and total bilirubin (BIL)) and levels of serum lipids (total cholesterol (CHOL), low-density lipoprotein cholesterol (LDL) and triglycerides (TG)). The associations between biomarkers were investigated both cross-sectionally using multiple linear regression (MLR) and Bayesian weighted quantile sum (BWQS) regression and prospectively using MLR. The models were adjusted for potential confounders and false discovery rate correction was applied to account for multiplicity. Results: A positive association between exposure to PFAS and PAH mixture and BIL (β = 28.6%, 95% CrI = 14.6-45.7%) was observed by the BWQS model. When the study population was stratified, in professional firefighters and controls the mixture showed a positive association with CHOL (β = 29.5%, CrI = 10.3-53.6%) and LDL (β = 26.7%, CrI = 8.3-48.5%). No statistically significant associations with individual compounds were detected using MLR. Conclusions: This study investigated the associations between exposure to PFAS and PAHs and biomarkers of cardiometabolic health in the Czech men, including firefighters. The results suggest that higher exposure to a mixture of these compounds is associated with an increase in BIL and the alteration of serum lipids, which can result in an unfavourable cardiometabolic profile.This work was funded by the European Union's Horizon 2020 research and innovation program under grant agreement No 857487 and supported under grant agreement No 857340, grant agreement No 857560 and grant agreement No 874627. This work was supported by the project National Institute for Research of Metabolic and Cardiovascular Diseases (Programme EXCELES, ID Project No. LX22NPO5104) - Funded by the European Union – Next Generation EU. This work was supported by the European Union's Horizon Europe research and innovation programme in the framework of the European Partnership for the Assessment of Risks from Chemicals (PARC) under grant agreement No 101057014. Views and opinions expressed are however those of the authors only and do not necessarily reflect those of the European Union or the Health and Digital Executive Agency. Neither the European Union nor the granting authority can be held responsible for them