13 research outputs found
Contraception in women over forty
Contraception in women over the age of 40 has received little attention, and accurate data are not readily available. This paper compares data from surveys from the United States and five major countries in Western Europe. Consideration is given to the possible effect on these women of the threat of reduced availability of suitable contraceptive methods as a result of current developments within society at large. This is of particular importance as it appears that, especially in Western Europe, contraception is underutilized in this age group. The benefits and risks of various methods of contraception are discussed. Use of the pill by older women remains controversial. Misconceptions about pill use and the IUD seem to be widespread among women of all age
A survey of family planning in the Philippines
In a multi-centre survey in 1986, 400 married Filipino women aged 15-40 were interviewed about their use of contraceptive methods, and specifically about their perceptions of the effects on health of oral contraceptives and their attitudes to contraceptive methods. The sample was randomly selected in the urban and rural areas surveyed and cannot be considered representative for the country as a whole. The results showed that women hold definitive views on the health risks posed by oral contraceptives and point to the importance of family planning clinics as a source of contraceptive counselling. The overall rate of contraceptive use must be regarded as insufficient to meet contraceptive need
Peripapillary Choroidal Thickness in Former Preterm and Full-Term Infants Aged From 4 to 10 Years
PURPOSE. The aim of the study was to investigate peripapillary choroidal thickness in former preterm and full-term infants with spectral-domain optical coherence tomography (SD-OCT). METHODS. Subanalysis of infants with successful peripapillary choroidal thickness measurements of a prospective, controlled, cross-sectional, hospital-based study in a tertiary center of maximum care. The study examined 503 infants aged 4 to 10 years at the time of examination. Infants were divided into different groups: group 1 born with gestational age (GA) >= 37 weeks, group 2 born with GA between 29 and 32 weeks without ROP (retinopathy of prematurity), group 3 born with GA <= 28 weeks without ROP, and group 4 born with GA <= 32 weeks and presence of ROP. RESULTS. Peripapillary choroidal measurements were available for 388 of 503 participants. No significant differences were found among the four groups for global peripapillary choroidal thickness. Multivariable analysis revealed no association with low GA, birth weight, ROP occurrence, perinatal adverse events, and logMAR visual acuity. Only infants born small for GA (SGA) revealed peripapillary choroidal thinning in the superior (P = 0.033) and nasal (P = 0.024) sectors compared with infants born appropriate for GA (AGA). Infants SGA had lower visual acuity than AGA infants (0.03 +/- 0.07 logMAR SGA versus 0.01 +/- 0.05 logMAR AGA; P = 0.029). CONCLUSIONS. Our results indicate that prematurity itself does not affect choroidal thickness in the peripapillary region. Only infants born SGA revealed peripapillary choroidal thinning compared with AGA infants. Our data indicate that fetal growth restriction leads to choroidal long-term alterations in the peripapillary region
Corneal Aberrations in Former Preterm Infants: Results From The Wiesbaden Prematurity Study
PURPOSE. To compare corneal aberrations in former preterm infants to that of full-term infants. METHODS. A prospective cross-sectional study was carried out measuring the corneal shape with Scheimpflug imaging in former preterm infants of gestational age (GA) = 37 weeks now being aged between 4 to 10 years. The main outcome measures were corneal aberrations including astigmatism (Zernike: Z(-2)(2); Z(2)(2)), coma (Z(-1)(3); Z(1)(3)), trefoil (Z(-3)(3); Z(3)(3)), spherical aberration (Z(0)(4)) and root-mean square of higher-order aberrations (RMS HOA). Multivariable analysis was performed to assess independent associations of gestational age groups and of retinopathy of prematurity (ROP) occurrence with corneal aberrations adjusting for sex and age at examination. RESULTS. A total of 259 former full-term and 226 preterm infants with a mean age of 7.2 +/- 2.0 years were included in this study. Statistical analysis revealed an association of extreme prematurity (GA <= 28 weeks) with higher-order and lower-order aberrations of the total cornea. Vertical coma was higher in extreme prematurity (P < 0.001), due to the shape of the anterior corneal surface, while there was no association with trefoil and spherical aberration. ROP was not associated with higher-order aberrations when adjusted for gestational age group. CONCLUSIONS. This study demonstrated that specific corneal aberrations were associated with extreme prematurity rather than with ROP occurrence
Correlation of morphological parameters and visual acuity with neurological development in former preterm children aged 4-10 years
Purpose The objective of this study was to investigate the relationship between visual acuity, peripapillary retinal nerve fibre layer (pRNFL), retinal thickness at the fovea and other factors with the neurologic status of former preterm children. Methods Results In this cross-sectional hospital based study in a maximum care tertiary centre, detailed anthropometric and ophthalmological data of former preterm children ranging from 4 to 10 years of age with a gestational age (GA) <= 32 weeks were assessed. Analyses of the correlation between pRNFL and foveal thickness, as well as visual acuity (VA) parameters at 4-10 years of age, with neurological development were evaluated at 2 years of age by Bayley Scales II of Infant Development, including Psychomotor Developmental Index (PDI) and Mental Developmental Index (MDI). Data were available for 106 former preterm children. Univariate analysis revealed a correlation between PDI with pRNFL thickness (B = 0.43; p = 0.013), VA (B = -29.2; p < 0.001), GA (B = 2.7; p = 0.002), retinopathy of prematurity (ROP; B = -16.3; p < 0.001) and intraventricular haemorrhages (IVH; B = -22.9; p < 0.001) but not with strabismus or foveal thickness. In the multivariable analysis, the association remained for visual acuity and IVH, but not for pRNFL thickness or ROP. Mental Developmental Index (MDI) was associated with visual acuity (B = -34.3; p = 0.001), GA (B = 2.53; p = 0.02) and IVH (B = -15.4; p = 0.02), the latter also in the multivariable analysis. Conclusion This study revealed an association between PDI at 2 years of age and lower visual acuity later in childhood. However, there was no correlation between retinal morphology and neurologic outcome in former preterm children after adjusting for several potential confounders
Prevalence and associated factors of strabismus in former preterm and full-term infants between 4 and 10 Years of age
Background: Limited data exist collating most of the associated factors for strabismus in one analysis. The aim of this study was to assess the prevalence of strabismus and to analyse associated factors in former preterm and full-term infants. Methods: In this cross-sectional study, 239 former preterm infants with gestational age (GA) = 37 weeks underwent detailed ophthalmologic examination in the age of 4-10 years and perinatal data assessment for risk factor analysis. Ophthalmologic examinations included cover testing, best corrected visual acuity, cycloplegic objective refraction, slit lamp as well as fundus examinations. For association analysis with strabismus, the following data was collected and included in multivariable analysis: sex, age at examination, anisometropia, myopic and hyperopic refractive error (>= 3 dioptres), astigmatism, birth weight percentile, gestational age, retinopathy of prematurity occurrence, maternal age at childbirth, mother smoking, breastfeeding < 3 months, artificial ventilation, intraventricular bleeding, and other perinatal adverse events. Results: Overall, 4/264 (2%) full-term infants, 15/125 (12%) preterm-infants with GA 29-32 weeks without ROP, 13/59 (22%) preterm infants with GA <= 28 weeks without ROP and 14/55 (26%) with GA <= 32 weeks with retinopathy of prematurity were affected by strabismus. In the multivariable regression model strabismus was associated with GA (OR = 0.84 per week; p = 0.001), hyperopic refractive error (OR = 4.22; p = 0.002) and astigmatism (OR = 1.68; p = 0.02). Conclusion: This investigation highlights that low gestational age and refraction of the eye are independent risk factors for strabismus, while the other factors show less independent influence
Axial Length and Anterior Segment Alterations in Former Preterm Infants and Full-Term Neonates Analyzed With Scheimpflug Imaging
Purpose: To compare the axial length and anterior segment alterations in preterm infants with and without retinopathy of prematurity with those of full-term infants. Methods: The Wiesbaden Prematurity Study investigated 503 participants of former gestational age = 37 weeks now being aged 4 to 10 years. This study included 485 participants in the prospective controlled cross-sectional, hospital-based study with successful Pentacam Scheimpflug imaging. Anterior segment parameters, axial length measurements, and associated factors were analyzed. Results: Corneal thickness did not differ between former preterm and full-term infants. Significant differences were found between preterm and full-term infants now aged = 8 years compared with full terms of the same age, we found a significant difference only in the corneal diameter. In multivariable analysis of the corneal diameter, we detected an association with birth weight and perinatal adverse events. Astigmatism correlated with birth weight and laser treatment, anterior chamber depth with birth weight, laser treatment and age at examination, and axial length with birth weight and age at examination. Conclusions: This study demonstrated altered axial length and anterior segment morphology in former preterm infants, especially in the first years of life. In addition, we observed that preterm infants seemed to catch up, so that the differences in ocular growth in terms of spherical equivalent, astigmatism, and axial length decreased within the first 8 years of life
Macular morphology in former preterm and full-term infants aged 4 to 10 years
Objective To analyse macular retinal and choroidal layer thickness in former preterm and full-term infants and to assess associated perinatal influence factors and functional correlation. This prospective controlled, cross-sectional, hospital-based study in a tertiary center of maximum care examined former preterm infants with a gestational age (GA) ae 32 weeks and full-term neonates currently aged 4 to 10 years. We investigated data from 397 infants, analysing total foveal retinal thickness and six distinct macular retinal layer and choroidal layer measurements via spectral-domain optical coherence tomography. Multivariable linear regression analysis was performed to investigate associations of layer thickness with GA and retinopathy of prematurity (ROP). Total retinal thickness in the fovea was thicker in former preterm infants with GA ae 28 weeks and in those with GA between 29-32 weeks compared to full-term infants independently of ROP. Occurrence of ROP was also associated with increased foveal thickness. Ganglion cell layer together with inner plexiform layer (GCL+IPL) was thinner in infants with GA ae 28 weeks than in full-term infants at 1000 and 2000 mu m distance from the fovea, but no association with ROP was present. Similar results were found for the photoreceptor layer. Total foveal retinal thickness was associated with low visual function. This study identified low gestational age and ROP occurrence as main determinants for foveal thickening. Furthermore, thinned GCL+IPL measurements were associated with lower gestational age. This study highlights the prognostic value of these maturity parameters influencing retinal morphology, which may affect visual function
Measurements of the ⁹⁰ ⁹¹ ⁹² ⁹⁴ ⁹⁶ Zr(n, γ) cross-sections at n_TOF
Neutron capture cross sections of the 90,91,91,94,96Zr have been measured over the energy range from 1 eV to 1 MeV at the spallation neutron facility n-TOF at CERN in 2003. The innovative features of the neutron beam, in particular the high instantaneous flux, the high energy resolution and low background, together with improvements of the neutron sensitivity of the capture detectors make this facility unique for neutron-induced reaction cross section measurements with much improved accuracy. The preliminary results of the Zr measurements show capture resonance strengths generally smaller than in previous measurements