True airspeed measured by airborne laser Doppler velocimeter

Velocimeter utilizing carbon dioxide laser measures true airspeed of aircraft. Results of flight tests indicate that clear-weather airspeeds can be measured with accuracy better than 0.1% at altitudes up to 3000 meters; measurements can be made at much greater altitudes in cloudy or turbid air

A phase locked dual channel spacecraft receiver for phase and group path measurements

Phase locked dual channel spacecraft receiver for phase and group path measurement

Interplanetary Electron Content Measured Between Earth and the Pioneer 6 and 7 Spacecraft Using Radio Propagation Effects

Electron number density, structure, and time variability of interplanetary media determined by radio propagation effects on Pioneer 6 and 7 spacecraft to earth communication

Handbook for design of containers of fluids and gases for spacecraft

Handbook guides selection of construction materials for liquids and gases used in rockets and spacecraft. Methods of design, fabrication, post-fabrication treatment, nondestructive testing, and repair are described in detail

Welding, brazing, and soldering handbook

Handbook gives information on the selection and application of welding, brazing, and soldering techniques for joining various metals. Summary descriptions of processes, criteria for process selection, and advantages of different methods are given

The role of body rotation in bacterial flagellar bundling

In bacterial chemotaxis, E. coli cells drift up chemical gradients by a series of runs and tumbles. Runs are periods of directed swimming, and tumbles are abrupt changes in swimming direction. Near the beginning of each run, the rotating helical flagellar filaments which propel the cell form a bundle. Using resistive-force theory, we show that the counter-rotation of the cell body necessary for torque balance is sufficient to wrap the filaments into a bundle, even in the absence of the swirling flows produced by each individual filament

Defective Tmprss3-Associated Hair Cell Degeneration in Inner Ear Organoids

Mutations in the gene encoding the type II transmembrane protease 3 (TMPRSS3) cause human hearing loss, although the underlying mechanisms that result in TMPRSS3-related hearing loss are still unclear. We combined the use of stem cell-derived inner ear organoids with single-cell RNA sequencing to investigate the role of TMPRSS3. Defective Tmprss3 leads to hair cell apoptosis without altering the development of hair cells and the formation of the mechanotransduction apparatus. Prior to degeneration, Tmprss3-KO hair cells demonstrate reduced numbers of BK channels and lower expressions of genes encoding calcium ion-binding proteins, suggesting a disruption in intracellular homeostasis. A proteolytically active TMPRSS3 was detected on cell membranes in addition to ER of cells in inner ear organoids. Our in vitro model recapitulated salient features of genetically associated inner ear abnormalities and will serve as a powerful tool for studying inner ear disorders

Testing T Invariance in the Interaction of Slow Neutrons with Aligned Nuclei

The study of five-fold (P even, T odd) correlation in the interaction of slow polarized neutrons with aligned nuclei is a possible way of testing the time reversal invariance due to the expected enhancement of T violating effects in compound resonances. Possible nuclear targets are discussed which can be aligned both dynamically as well as by the "brute force" method at low temperature. A statistical estimation is performed of the five-fold correlation for low lying p wave compound resonances of the $^{121}$Sb, $^{123}$Sb and $^{127}$I nuclei. It is shown that a significant improvement can be achieved for the bound on the intensity of the fundamental parity conserving time violating (PCTV) interaction.Comment: 22 pages, 5 figures, published versio

Exposure to Household Air Pollution from Biomass-Burning Cookstoves and HbA1c and Diabetic Status Among Honduran Women

Household air pollution from biomass cookstoves is estimated to be responsible for more than two and a half million premature deaths annually, primarily in low and middle‐income countries where cardiometabolic disorders, such as Type II Diabetes, are increasing. Growing evidence supports a link between ambient air pollution and diabetes, but evidence for household air pollution is limited. This cross‐sectional study of 142 women (72 with traditional stoves and 70 with cleaner‐burning Justa stoves) in rural Honduras evaluated the association of exposure to household air pollution (stove type, 24‐hour average kitchen and personal fine particulate matter [PM2.5] mass and black carbon) with glycated hemoglobin (HbA1c) levels and diabetic status based on HbA1c levels. The prevalence ratio (PR) per interquartile range increase in pollution concentration indicated higher prevalence of prediabetes/diabetes (vs normal HbA1c) for all pollutant measures (eg, PR per 84 μg/m3 increase in personal PM2.5, 1.49; 95% confidence interval [CI], 1.11‐2.01). Results for HbA1c as a continuous variable were generally in the hypothesized direction. These results provide some evidence linking household air pollution with the prevalence of prediabetes/diabetes, and, if confirmed, suggest that the global public health impact of household air pollution may be broader than currently estimated