95 research outputs found

    On the Issue of the Effectiveness Peculiarities of Prosecutorial Activity

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    The article deals with the analysis of the complex of theoretical and practical issues related to the lawyer’s activities and the peculiarities of the prosecutor’s activity efficiency increase; the assessment criteria of the prosecutorial activity effectiveness have been considered by the author

    ВИЗНАЧЕННЯ ЕФЕКТИВНОСТІ ІСНУЮЧИХ ГІДРОЕНЕРГЕТИЧНИХ СИСТЕМ

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    The urgency, problem condition and the basic operating factors defining working efficiency of the basic hydropower equipment of HYDROELECTRIC POWER STATION are shown. The basic components of energy expenses efficiency in technological systems of electric energy development are considered and classified. Influences of the basic components of technical and operational factors on efficiency level are reflected. The substantiation is performed and the direction of the working factors research affecting the change of the hydrounit electric parametres is defined. Ways of an overall performance increase of the operative equipment of HYDROELECTRIC POWER STATION are offered. The cited data can be used at modernisation of energy hydropower convertersПоказаны актуальность, состояние проблемы и основные действующие факторы, определяющие рабочую эффективность основного гидроэнергетического оборудования ГЭС. Рассмотрены и классифицированы основные составляющие эфекивности затрат энергии в технологических системах выработки электрической энергии. Отражены влияния основных составляющих технических и эксплуатационых факторов на уровень эффективности. Приведено обоснование и определено направление исследования рабочих факторов, влияющих на изменение электрических параметров гидроагрегата. Предложены пути повышения эффективности работы действующего оборудования ГЭС. Приведенные данные могут быть использованы при модернизации гидроэнергетических преобразователей энергии.Показані актуальність, стан проблеми й основні діючі чинники, що визначають робочу ефективність основного гідроенергетичного устаткування ГЕС. Розглянуті і класифіковані основні складові ефективності витрат енергії в технологічних системах вироблення електричної енергії. Відображені впливи основних складових технічних й експлуатаційних чинників на рівень ефективності. Приведено обґрунтування і визначений напрям дослідження робочих чинників, що впливають на зміну електричних параметрів гідроагрегату. Запропоновані шляхи підвищення ефективності роботи діючого устаткування ГЕС. Приведені дані можуть бути використані при модернізації гідроенергетичних перетворювачів енергії

    An Investigation of Products of (n, ƒ), (n, ɣ) and (ɣ, ƒ), (ɣ, xn, p) Reactions on Samples of Uranium and Bismuth using the Phasotron and LINAС-200 Accelerators at JINR: Experiments and Calculations

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    The paper presents the results of physical experiments with 238U and 209Bi samples at the Nuclotron, Phasotron and LINAC-200 accelerators of the Joint Institute for Nuclear Research, with the results processed using the FLUKA, GEANT4 and MCNP programs

    Roquefort Cheese Proteins Inhibit Chlamydia pneumoniae

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    Inflammation in atherosclerosis, which could be associated with some subclinical infections such as C. pneumoniae, is one of the key factors responsible for the development of clinical complications of this disease. We report that a proprietary protein extract isolated from Roquefort cheese inhibits the propagation of C. pneumoniae in a human HL cell line in a dose-dependent manner, as revealed by the immunofluorescence analysis. These changes were accompanied by a significant reduction in the infective progeny formation over the protein extract range of 0.12–0.5 μg/mL. Moreover, short term feeding of mice with Roquefort cheese (twice, 10 mg per mouse with an interval of 24 hours) led to the inhibition of the migration of peritoneal leukocytes caused by intraperitoneal injection of E. coli lipopolysaccharide. These changes were complemented by a reduction in neutrophil count and a relative increase in peritoneal macrophages, suggesting that ingestion of Roquefort could promote regenerative processes at the site of inflammation. The ability of this protein to inhibit propagation of Chlamydia infection, as well as the anti-inflammatory and proregenerative effects of Roquefort itself, may contribute to the low prevalence of cardiovascular mortality in France where consumption of fungal fermented cheeses is the highest in the world

    Magnetoelastic effects in low-dimensional magnetic systems

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    We consider a new realization of magnetoelastic interactions in low-dimensional magnetic systems. We show that low-dimensional spin systems are unstable with respect to the spontaneous appearance of alternating distortions of the positions of the three-dimensional nonmagnetic atoms (ligands), that surround the magnetic ions. Those distortions are supplemented by the spontaneous onset of alternating effective g factors of the magnetic ions in the phase with short-range interactions. We discuss the possibility of observing the effect in an uniform external magnetic field, which in the situation considered produces both magnetization and staggered magnetization of the magnetic subsystem. The connection of the proposed theory with recent experiments on effectively low-dimensional magnetic systems (organic spin chains, heavy-fermion compounds, rare-earth molybdates) is discussed

    Genetics of Host Response to Leishmania tropica in Mice – Different Control of Skin Pathology, Chemokine Reaction, and Invasion into Spleen and Liver

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    Several hundred million people are exposed to the risk of leishmaniasis, a disease caused by intracellular protozoan parasites of several Leishmania species and transmitted by phlebotomine sand flies. In humans, L. tropica causes cutaneous form of leishmaniasis with painful and long-persisting lesions in the site of the insect bite, but the parasites can also penetrate to internal organs. The relationship between the host genes and development of the disease was demonstrated for numerous infectious diseases. However, the search for susceptibility genes in the human population could be a difficult task. In such cases, animal models may help to discover the role of different genes in interactions between the parasite and the host. Unfortunately, the literature contains only a few publications about the use of animals for L. tropica studies. Here, we report an animal model suitable for genetic, pathological and drug studies in L. tropica infection. We show how the host genotype influences different disease symptoms: skin lesions, parasite dissemination to the lymph nodes, spleen and liver, and increase of levels of chemokines CCL2, CCL3 and CCL5 in serum
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