4,307 research outputs found

    Trust at the heart of the issue: Towards the building of trust organisations

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    This paper examines the role of trust in the shaping of rules and relationships within and between organisations. Firstly, we examine strands of literature on how trust constitutes an organising principle for intra- and inter-organisational trust levels to exist. Then we examine the downside of organisational trust when violated and not achieved. We then propose a model which examines the interplay between the developments of trust within and between organisations. Finally, we surmise by promoting explicitly the broader societal impact and relevance of organisational trust

    All we need is trust: Trust in West African cross border networks

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    This paper aims to develop an understanding of trust in cross border trade networks dominating West African markets. To date most of the literature on trust and network relationships reveal a paucity of studies about West African traders. This paper attempts to address this gap by examining a range of relationships that have evolved as a result of weak formal institutions. Within the remit of this paper, we make an attempt to establish the role of trust in overcoming barriers to the survival of small businesses in West Africa. As this is a development paper, the organisation of this paper is three fold: firstly we commence by examining the topicality of trust from relevant literature. (2) we attempt to bring these conceptualisations to bear by examining the various complex economic and social relationships that shape cross border trade.(3) our discourse will be elucidated with the case of twelve traders operating between Nigeria, Ghana, Benin and Bukinafaso

    Stochastic Modeling for the Expression of a Gene Regulated by Competing Transcription Factors

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    It is widely accepted that gene expression regulation is a stochastic event. The common approach for its computer simulation requires detailed information on the interactions of individual molecules, which is often not available for the analyses of biological experiments. As an alternative approach, we employed a more intuitive model to simulate the experimental result, the Markov-chain model, in which a gene is regulated by activators and repressors, which bind the same site in a mutually exclusive manner. Our stochastic simulation in the presence of both activators and repressors predicted a Hill-coefficient of the dose-response curve closer to the experimentally observed value than the calculated value based on the simple additive effects of activators alone and repressors alone. The simulation also reproduced the heterogeneity of gene expression levels among individual cells observed by Fluorescence Activated Cell Sorting analysis. Therefore, our approach may help to apply stochastic simulations to broader experimental data

    Trust and Distrust in Nigerian Supply Chain Relationships

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    Abstract Purpose- To date, most of the literature on trust and distrust reveal a paucity of studies about Nigerian Supply chain relationships. Specifically, this paper attempts to address this gap by examining how trust is developed and repaired in supply chain relationships. Design/methodology/approach- Within the scope of this paper, an interpretivist approach was adopted in response to calls for qualitative studies on supply chain relationships. Face to face semi-structured interviews with 12 supplier/customers active in Nigerian trade provided insights into the importance of trust and distrust in enduring supply chain relationships. Data was analysed using iterations from interviews held with the respondents. These iterations demonstrate the key role trust plays in developing and maintaining supply chain relationships whereas distrust deters cooperative relationships. Findings- Key factors were considered in developing an understanding of how trust and distrust mechanisms affect the coordination of supply chain performance. Three distinct types of trust-calculus based trust (CBT), identification based trust (IBT) and knowledge based trust (KBT) are considered to play an important role in maintaining and developing fruitful relationships. Conversely, the repair of two levels of distrust-calculus based distrust and identification based distrust is crucial to enduring supply chain relationships. Research limitations/implications- The importance of taking trust and distrust seriously stems from its unique contextual embeddedness. This study fills a gap in the literature by providing insights into how potential customers and suppliers can leverage on trust to improve their supply chain capacities while suggesting remedial actions when trust is violated. Originality- The paper enriches the view that trust and distrust are crucial in explaining Nigerian supply chain relationships. In a broader context, the complementary relationships between both mechanisms highlight the social advantage of trusting behaviour in overall performance of supply chains

    Predictors of betel quid chewing behavior and cessation patterns in Taiwan aborigines

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    BACKGROUND: Betel quid, chewed by about 600 million people worldwide, is one of the most widely used addictive substances. Cessation factors in betel quid chewers are unknown. The present study explores prevalence and the quit rate of betel quid chewing in Taiwan aborigines. Our goal was to delineate potential predictors of chewing cessation. METHODS: A stratified random community-based survey was designed for the entire aborigines communities in Taiwan. A total of 7144 participants were included between June 2003 and May 2004 in this study. Information on sociodemographic characteristics, such as gender, age, obesity, education years, marital status, ethnicity, and habits of betel quid chewing, smoking and drinking was collected by trained interviewers. RESULTS: The prevalence of betel quid chewers was 46.1%. Betel quid chewing was closely associated with obesity (OR = 1.61; 95% CI: 1.40–1.85). Betel quid chewers were most likely to use alcohol and cigarettes together. Quit rate of betel quid chewers was 7.6%. Betel quid chewers who did not drink alcohol were more likely to quit (OR = 1.89; 95% CI: 1.43–2.50). Alcohol use is a significant factor related to cessation of betel quid chewing, but smoking is not. CONCLUSION: Taiwan aborigines have a high prevalence of betel quid chewers and a low quit rate. Alcohol use is strongly association with betel quid chewing. Efforts to reduce habitual alcohol consumption might be of benefit in cessation of betel quid chewing

    Rare Earth Element Adsorption to Clay Minerals: Mechanistic Insights and Implications for Recovery from Secondary Sources

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    \ua9 2024 American Chemical Society.The energy transition will have significant mineral demands and there is growing interest in recovering critical metals, including rare earth elements (REE), from secondary sources in aqueous and sedimentary environments. However, the role of clays in REE transport and deposition in these settings remains understudied. This work investigated REE adsorption to the clay minerals illite and kaolinite through pH adsorption experiments and extended X-ray absorption fine structure (EXAFS). Clay type, pH, and ionic strength (IS) affected adsorption, with decreased adsorption under acidic pH and elevated IS. Illite had a higher adsorption capacity than kaolinite; however, >95% adsorption was achieved at pH ∼7.5 regardless of IS or clay. These results were used to develop a surface complexation model with the derived binding constants used to predict REE speciation in the presence of competing sorbents. This demonstrated that clays become increasingly important as pH increases, and EXAFS modeling showed that REE can exist as both inner- and outer-sphere complexes. Together, this indicated that clays can be an important control on the transport and enrichment of REE in sedimentary systems. These findings can be applied to identify settings to target for resource extraction or to predict REE transport and fate as a contaminant

    Large CP Violation in B_s Meson Mixing with EDM constraint in Supersymmetry

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    Motivated by the recent measurement of the like-sign dimuon charge asymmetry, we investigate anomalous CP violation in the B_s- bar{B}_s mixing within the supersymmetry. We show that when gluino diagrams dominate supersymmetry contributions, it is very difficult to realize a large B_s- bar{B}_s mixing phase under the constraint from electric dipole moments barring cancellations. This constraint can be ameliorated by supposing superparticles decoupled. In this limit, we find that it is possible to achieve the large CP asymmetry, and the branching ratio of B_s -> mu^+ mu^- tends to become sizable.Comment: 20 pages, 5 figure

    Ears of the Armadillo: Global Health Research and Neglected Diseases in Texas

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    Neglected tropical diseases (NTDs) have\ud been recently identified as significant public\ud health problems in Texas and elsewhere in\ud the American South. A one-day forum on the\ud landscape of research and development and\ud the hidden burden of NTDs in Texas\ud explored the next steps to coordinate advocacy,\ud public health, and research into a\ud cogent health policy framework for the\ud American NTDs. It also highlighted how\ud U.S.-funded global health research can serve\ud to combat these health disparities in the\ud United States, in addition to benefiting\ud communities abroad

    Sensory Electrical Stimulation Improves Foot Placement during Targeted Stepping Post-Stroke

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    Proper foot placement is vital for maintaining balance during walking, requiring the integration of multiple sensory signals with motor commands. Disruption of brain structures post-stroke likely alters the processing of sensory information by motor centers, interfering with precision control of foot placement and walking function for stroke survivors. In this study, we examined whether somatosensory stimulation, which improves functional movements of the paretic hand, could be used to improve foot placement of the paretic limb. Foot placement was evaluated before, during, and after application of somatosensory electrical stimulation to the paretic foot during a targeted stepping task. Starting from standing, twelve chronic stroke participants initiated movement with the non-paretic limb and stepped to one of five target locations projected onto the floor with distances normalized to the paretic stride length. Targeting error and lower extremity kinematics were used to assess changes in foot placement and limb control due to somatosensory stimulation. Significant reductions in placement error in the medial–lateral direction (p = 0.008) were observed during the stimulation and post-stimulation blocks. Seven participants, presenting with a hip circumduction walking pattern, had reductions (p = 0.008) in the magnitude and duration of hip abduction during swing with somatosensory stimulation. Reductions in circumduction correlated with both functional and clinical measures, with larger improvements observed in participants with greater impairment. The results of this study suggest that somatosensory stimulation of the paretic foot applied during movement can improve the precision control of foot placement

    M2C Polarization by Baicalin Enhances Efferocytosis Than IL-4 Induced M2 Macrophages

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    Baicalin adalah bahan aktif utama yang diisolasi dari jamu Cina (Scutellaria baicalensis Georgi). Meskipun baicalin dapat menginduksi polarisasi makrofag M2, subtipe dari makrofag terpolarisasi baicalin tidak diketahui. Dalam penelitian ini, kami mengkarakterisasi bahwa makrofag yang berasal dari sumsum tulang tikus dapat dipolarisasi menjadi makrofag M2C oleh baicali
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