820 research outputs found
Substances Dissolved in Rain and Snow
Considerable interest has been shown throughout the country on the determination of the character and quantity of substances dissolved in rain and snow. The accompanying article is a continuation of the record of the analyses of rain and snow which have been carried on at Cornell College for a number of years
Comprehensive determination of the high-pressure structural behaviour of BaTiO<sub>3</sub>
We have mapped the phase diagram of BaTiO3 more extensively than previous attempts using high-pressure neutron-powder diffraction. The mapping of the phase diagram has been performed using isothermal compression at fixed temperatures (175, 225, 290, 480 K) within each of the known crystallographic phases, up to ∼6 GPa using a large volume press. The crystallographic structure of each phase has been measured, and the determined absolute atomic displacements of all atoms within the cell have provided detailed information on the order of the phase transitions observed, and the behaviour of the ferroelectric dipole moment.Publisher PDFPeer reviewe
The 2016 Reactivations of Main-Belt Comets 238P/Read and 288P/(300163) 2006 VW139
We report observations of the reactivations of main-belt comets 238P/Read and
288P/(300163) 2006 VW139, that also track the evolution of each object's
activity over several months in 2016 and 2017. We additionally identify and
analyze archival SDSS data showing 288P to be active in 2000, meaning that both
238P and 288P have now each been confirmed to be active near perihelion on
three separate occasions. From data obtained of 288P from 2012-2015 when it
appeared inactive, we find best-fit R-band H,G phase function parameters of
H_R=16.80+/-0.12 mag and G_R=0.18+/-0.11, corresponding to effective component
radii of r_c=0.80+/-0.04 km, assuming a binary system with equally-sized
components. Fitting linear functions to ejected dust masses inferred for 238P
and 288P soon after their observed reactivations in 2016, we find an initial
average net dust production rate of 0.7+/-0.3 kg/s and a best-fit start date of
2016 March 11 (when the object was at a true anomaly of -63 deg) for 238P, and
an initial average net dust production rate of 5.6+/-0.7 kg/s and a best-fit
start date of 2016 August 5 (when the object was at a true anomaly of -27 deg)
for 288P. Applying similar analyses to archival data, we find similar start
points for previous active episodes for both objects, suggesting that minimal
mantle growth or ice recession occurred between the active episodes in
question. Some changes in dust production rates between active episodes are
detected, however. More detailed dust modeling is suggested to further clarify
the process of activity evolution in main-belt comets.Comment: 21 pages, 9 figures, accepted by A
Dietary long-chain, but not medium-chain, triglycerides impair exercise performance and uncouple cardiac mitochondria in rats.
Short-term consumption of a high-fat diet impairs exercise capacity in both rats and humans, and increases expression of the mitochondrial uncoupling protein, UCP3, in rodent cardiac and skeletal muscle via activation of the transcription factor, peroxisome proliferator-activated receptor α (PPARα). Unlike long-chain fatty acids however, medium-chain fatty acids do not activate PPARα and do not increase muscle UCP3 expression. We therefore investigated exercise performance and cardiac mitochondrial function in rats fed a chow diet (7.5% kcal from fat), a long-chain triglyceride (LCT) rich diet (46% kcal from LCTs) or a medium-chain triglyceride (MCT) rich diet (46% kcal from MCTs). Rats fed the LCT-rich diet for 15 days ran 55% less far than they did at baseline, whereas rats fed the chow or MCT-rich diets neither improved nor worsened in their exercise capacities. Moreover, consumption of an LCT-rich diet increased cardiac UCP3 expression by 35% and decreased oxidative phosphorylation efficiency, whereas consumption of the MCT-rich diet altered neither UCP3 expression nor oxidative phosphorylation efficiency. Our results suggest that the negative effects of short-term high-fat feeding on exercise performance are predominantly mediated by long-chain rather than medium-chain fatty acids, possibly via PPARα-dependent upregulation of UCP3.RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are
Spatiotemporal Dynamics of Word Processing in the Human Brain
We examined the spatiotemporal dynamics of word processing by recording the electrocorticogram (ECoG) from the lateral frontotemporal cortex of neurosurgical patients chronically implanted with subdural electrode grids. Subjects engaged in a target detection task where proper names served as infrequent targets embedded in a stream of task-irrelevant verbs and nonwords. Verbs described actions related to the hand (e.g, throw) or mouth (e.g., blow), while unintelligible nonwords were sounds which matched the verbs in duration, intensity, temporal modulation, and power spectrum. Complex oscillatory dynamics were observed in the delta, theta, alpha, beta, low, and high gamma (HG) bands in response to presentation of all stimulus types. HG activity (80–200 Hz) in the ECoG tracked the spatiotemporal dynamics of word processing and identified a network of cortical structures involved in early word processing. HG was used to determine the relative onset, peak, and offset times of local cortical activation during word processing. Listening to verbs compared to nonwords sequentially activates first the posterior superior temporal gyrus (post-STG), then the middle superior temporal gyrus (mid-STG), followed by the superior temporal sulcus (STS). We also observed strong phase-locking between pairs of electrodes in the theta band, with weaker phase-locking occurring in the delta, alpha, and beta frequency ranges. These results provide details on the first few hundred milliseconds of the spatiotemporal evolution of cortical activity during word processing and provide evidence consistent with the hypothesis that an oscillatory hierarchy coordinates the flow of information between distinct cortical regions during goal-directed behavior
The Secret Life of Collagen: Temporal Changes in Nanoscale Fibrillar Pre-Strain and Molecular Organization during Physiological Loading of Cartilage
Articular
cartilage is a natural biomaterial whose structure at
the micro- and nanoscale is critical for healthy joint function and
where degeneration is associated with widespread disorders such as
osteoarthritis. At the nanoscale, cartilage mechanical functionality
is dependent on the collagen fibrils and hydrated proteoglycans that
form the extracellular matrix. The dynamic response of these ultrastructural
building blocks at the nanoscale, however, remains unclear. Here we
measure time-resolved changes in collagen fibril strain, using small-angle
X-ray diffraction during compression of bovine and human cartilage
explants. We demonstrate the existence of a collagen fibril tensile
pre-strain, estimated from the D-period at approximately 1–2%,
due to osmotic swelling pressure from the proteoglycan. We reveal
a rapid reduction and recovery of this pre-strain which occurs during
stress relaxation, approximately 60 s after the onset of peak load.
Furthermore, we show that this reduction in pre-strain is linked to
disordering in the intrafibrillar molecular packing, alongside changes
in the axial overlapping of tropocollagen molecules within the fibril.
Tissue degradation in the form of selective proteoglycan removal disrupts
both the collagen fibril pre-strain and the transient response during
stress relaxation. This study bridges a fundamental gap in the knowledge
describing time-dependent changes in collagen pre-strain and molecular
organization that occur during physiological loading of articular
cartilage. The ultrastructural details of this transient response
are likely to transform our understanding of the role of collagen
fibril nanomechanics in the biomechanics of cartilage and other hydrated
soft tissues
Uterine Rupture by Intended Mode of Delivery in the UK: A National Case-Control Study
A case-control study using UK data estimates the risk of uterine rupture in subsequent deliveries amongst women who have had a previous caesarean section
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Low-intermediate-temperature, high-pressure thermoelastic and crystallographic properties of thermoelectric clausthalite (PbSe-I)
The thermoelastic properties of the rock-salt structured thermoelectric lead selenide
(clausthalite, PbSe-I) have been determined using neutron powder diffraction techniques for
the temperature interval 10 - 500 K at ambient pressure, and 0 - 5.2 GPa at 298, and 150 K.
Within this temperature range, lead selenide can be described using the same selfconsistent
phenomenological model developed for the isostructural phases lead sulfide
(PbS) and lead telluride (PbTe) in which the cations and anions behave as independent
Debye oscillators (vibrational Debye temperatures of PbSe-I: Pb 111(1) K, Se 205(1) K).
Simultaneous fitting of the unit cell volume and isochoric heat capacity to a two-term Debye
internal energy function gives characteristic temperatures of 104(3) K and 219(5) K in
excellent agreement with the two vibrational Debye temperatures derived from fitting the
individual atomic displacement parameters. Grüneisen constants for the two term fits are
1.79 and 2.28 for the lower and upper characteristic temperature respectively. The
calculated thermodynamic Grüneisen parameter increases monotonically from 2.03 at 10 K,
to a maximum 2.22 at 100 K before decreasing back to 2.00 at 298 K and is broadly in
agreement with the average of the two Grüneisen parameters associated with the two-term
internal energy function. Despite the simplicity of the model, the calculated phonon density of
states that is implicit within the two-term Debye model is found to show fair agreement with
the full and partial vibrational densities of states derived from density functional theory
(DFT). The bulk modulus and its pressure derivative at 298 K are 47.9(4) GPa and 5.4(2)
respectively by fitting the pressure dependence of the unit cell volume to a 3rd order Birch-
Murnaghan equation-of-state. For lower temperatures (T < 300 K) the high-pressure
transition to PbSe-II is associated with a steep initial Clapeyron slope of 151 K GPa-1
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