Thermal Conduction in Magnetized Turbulent Gas

Using numerical methods, we systematically study in the framework of ideal MHD the effect of magnetic fields on heat transfer within a turbulent gas. We measure the rates of passive scalar diffusion within magnetized fluids and make the comparisons a) between MHD and hydro simulations, b) between different MHD runs with different values of the external magnetic field (up to the energy equipartition value), c) between thermal conductivities parallel and perpendicular to magnetic field. We do not find apparent suppression of diffusion rates by the presence of magnetic fields, which implies that magnetic fields do not suppress heat diffusion by turbulent motions.Comment: 4 pages; 2 figures; submitted to Ap

Relative role of short interfacial fingers and long internally driven streamers in convective flows below growing sea ice

Convective dynamics developing below growing sea ice are studied experimentally by freezing salt water from above in a quasi-two-dimensional Hele-Shaw cell. Observations of the convective processes are made with Schlieren and direct imaging systems, allowing visualization both under and within the growing ice. Buoyancy-driven flows are seen to develop under the ice layer via two different mechanisms: On one hand, brine diffuses out from the ice layer creating a denser boundary layer of enhanced salinity, which triggers boundary layer convection resulting in small-scale interfacial fingers. On the other hand, internal flow within brine drainage channels inside the ice is observed flushing out longer-scale convective streamers at given locations at the ice-water interface. Streamers descend in the bulk aqueous layer faster and for longer distances than fingers. Simulations confirm that, despite nonlinear interactions between fingers and streamers, the different speeds observed can be correlated to different density differences between the interfacial or internal rejection and the underlying bulk salt water. Estimates of relative mass fluxes through the interface by the two mechanisms suggest that, when streamers are active, the mass of salt rejected through the streamer pathway can be larger than the one expelled through the finger pathway. However, as fingers are maintained throughout the ice growth while the rejection from brine channels features an intermittent "on-off" behavior, there are certain periods of time when the mass flux of the two mechanisms is similar, but also some time intervals during which the flux due to interfacial short fingers becomes dominant.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Characteristic cohomology of pp-form gauge theories

The characteristic cohomology $H^k_{char}(d)$ for an arbitrary set of free $p$-form gauge fields is explicitly worked out in all form degrees $k<n-1$, where $n$ is the spacetime dimension. It is shown that this cohomology is finite-dimensional and completely generated by the forms dual to the field strengths. The gauge invariant characteristic cohomology is also computed. The results are extended to interacting $p$-form gauge theories with gauge invariant interactions. Implications for the BRST cohomology are mentioned.Comment: Latex file, no figures, 44 page

Developmental Fluoxetine Exposure Normalizes the Long-Term Effects of Maternal Stress on Post-Operative Pain in Sprague-Dawley Rat Offspring

Early life events can significantly alter the development of the nociceptive circuit. In fact, clinical work has shown that maternal adversity, in the form of depression, and concomitant selective serotonin reuptake inhibitor (SSRI) treatment influence nociception in infants. The combined effects of maternal adversity and SSRI exposure on offspring nociception may be due to their effects on the developing hypothalamic-pituitary-adrenal (HPA) system. Therefore, the present study investigated long-term effects of maternal adversity and/or SSRI medication use on nociception of adult Sprague-Dawley rat offspring, taking into account involvement of the HPA system. Dams were subject to stress during gestation and were treated with fluoxetine (2×/5 mg/kg/day) prior to parturition and throughout lactation. Four groups of adult male offspring were used: 1. Control+Vehicle, 2. Control+Fluoxetine, 3. Prenatal Stress+Vehicle, 4. Prenatal Stress+Fluoxetine. Results show that post-operative pain, measured as hypersensitivity to mechanical stimuli after hind paw incision, was decreased in adult offspring subject to prenatal stress alone and increased in offspring developmentally exposed to fluoxetine alone. Moreover, post-operative pain was normalized in prenatally stressed offspring exposed to fluoxetine. This was paralleled by a decrease in corticosteroid binding globulin (CBG) levels in prenatally stressed offspring and a normalization of serum CBG levels in prenatally stressed offspring developmentally exposed to fluoxetine. Thus, developmental fluoxetine exposure normalizes the long-term effects of maternal adversity on post-operative pain in offspring and these effects may be due, in part, to the involvement of the HPA system

Physical activity to improve cognition in older adults: can physical activity programs enriched with cognitive challenges enhance the effects? A systematic review and meta-analysis

: EPHPP quality rating scores (DOCX 38 kb

Modulators of Cytoskeletal Reorganization in CA1 Hippocampal Neurons Show Increased Expression in Patients at Mid-Stage Alzheimer's Disease

During the progression of Alzheimer's disease (AD), hippocampal neurons undergo cytoskeletal reorganization, resulting in degenerative as well as regenerative changes. As neurofibrillary tangles form and dystrophic neurites appear, sprouting neuronal processes with growth cones emerge. Actin and tubulin are indispensable for normal neurite development and regenerative responses to injury and neurodegenerative stimuli. We have previously shown that actin capping protein beta2 subunit, Capzb2, binds tubulin and, in the presence of tau, affects microtubule polymerization necessary for neurite outgrowth and normal growth cone morphology. Accordingly, Capzb2 silencing in hippocampal neurons resulted in short, dystrophic neurites, seen in neurodegenerative diseases including AD. Here we demonstrate the statistically significant increase in the Capzb2 expression in the postmortem hippocampi in persons at mid-stage, Braak and Braak stage (BB) III-IV, non-familial AD in comparison to controls. The dynamics of Capzb2 expression in progressive AD stages cannot be attributed to reactive astrocytosis. Moreover, the increased expression of Capzb2 mRNA in CA1 pyramidal neurons in AD BB III-IV is accompanied by an increased mRNA expression of brain derived neurotrophic factor (BDNF) receptor tyrosine kinase B (TrkB), mediator of synaptic plasticity in hippocampal neurons. Thus, the up-regulation of Capzb2 and TrkB may reflect cytoskeletal reorganization and/or regenerative response occurring in hippocampal CA1 neurons at a specific stage of AD progression

Anisotrophy of magnetohydrodynamic turbulence at low magnetic Reynolds number

Turbulent fluctuations in magnetohydrodynamic flows are known to become anisotropic under the action of a sufficiently strong magnetic field. We investigate this phenomenon in the case of low magnetic Reynolds number using direct numerical simulations and large eddy simulations of a forced flow in a periodic box. A series of simulations is performed with different strengths of the magnetic field, varying Reynolds number, and two types of forcing, one of which is isotropic and the other limited to two-dimensional flow modes. We find that both the velocity anisotropy (difference in the relative amplitude of the velocity components) and the anisotropy of the velocity gradients are predominantly determined by the value of the magnetic interaction parameter. The effects of the Reynolds number and the type of forcing are much weaker. We also find that the anisotropy varies only slightly with the length scale. <br/