473 research outputs found

    Novel high-speed induction motor for a commercial centrifugal compressor

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    Copyright © 2000 IEEEThis paper describes the electrical, mechanical, and metallurgical design, construction, and testing of a novel low-cost high-speed high-efficiency induction motor to drive a new type of small centrifugal compressor in industrial cooling applications. The 28-shaft-hp 50-kr/min motor features a unique laminated rotor with a multifunction high-strength copper-alloy cage brazed with a novel process. Relatively thin high-silicon steel laminations were used to achieve low losses and high mechanical strength at low cost. Different heat treatments for the stator and rotor laminations were used to optimize the mechanical and magnetic properties. The preprototype motors achieved about 94% (electromagnetic) efficiency at the rated point, including inverter harmonics, while meeting cost (less than one-tenth of aerospace practice) and produceability goals.Wen L. Soong, Gerald B. Kliman, Roger N. Johnson, Raymond A. White, and Joseph E. Mille

    Plasma Magnetohydrodynamics and Energy Conversion

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    Contains reports on four research projects.National Science Foundation (Grant G-24073)United States Air Force, Aeronautical Systems Division (Contract AF33(615)-1083

    NETWORK INTERACTION IN THE EDUCATION SYSTEM AS A RESOURCE FOR RENEWAL AND INNOVATIVE DEVELOPMENT

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    В статье рассматривается сетевое взаимодействие как ведущая форма / основной ресурс обновления и инновационного развития образовательных организацийThe article considers network interaction as a leading form/main resource for updating and innovative development of educational organization

    Plasma Magnetohydrodynamics and Energy Conversion

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    Contains research objectives and reports on x research projects.National Science Foundation under Grant G-9330U.S. Air Force (Aeronautical Systems Division) under Contract AF33(616)-7624 with the Flight Accessories Laboratory, Wright-Patterson Air Force Base, Ohi

    Plasma Magnetohydrodynamics and Energy Conversion

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    Contains reports on eight research projects.National Science Foundation (Grant G-24073)United States Air Force, Aeronautical Systems Division, Aeronautical Accessories Laboratory, Wright-Patterson Air Force Base (Contract AF33(616)-7624)United States Air Force, Office of Scientific Research of the Office of Aerospace Research (Research Grant No. 62-308

    Plasma Magnetohydrodynamics and Energy Conversion

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    Contains reports on seven research projects.U. S. Air Force (Aeronautical Systems Division) under Contract AF33 (615)-1083 with the Air Force Aero Propulsion Laboratory, Wright-Patterson Air Force Base, OhioNational Science Foundation (Grant GK-57

    The effects of financialisation and financial development on investment: Evidence from firm-level data in Europe

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    In this paper we estimate the effects of financialization on physical investment in selected western European countries using panel data based on the balance-sheets of publicly listed non-financial companies (NFCs) supplied by Worldscope for the period 1995-2015. We find robust evidence of an adverse effect of both financial payments (interests and dividends) and financial incomes on investment in fixed assets by the NFCs. This finding is robust for both the pool of all Western European firms and single country estimations. The negative impacts of financial incomes are non-linear with respect to the companies’ size: financial incomes crowd-out investment in large companies, and have a positive effect on the investment of only small, relatively more credit-constrained companies. Moreover, we find that a higher degree of financial development is associated with a stronger negative effect of financial incomes on companies’ investment. This finding challenges the common wisdom on ‘finance-growth nexus’. Our findings support the ‘financialization thesis’ that the increasing orientation of the non-financial sector towards financial activities is ultimately leading to lower physical investment, hence to stagnant or fragile growth, as well as long term stagnation in productivity

    The scale of population structure in Arabidopsis thaliana

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    The population structure of an organism reflects its evolutionary history and influences its evolutionary trajectory. It constrains the combination of genetic diversity and reveals patterns of past gene flow. Understanding it is a prerequisite for detecting genomic regions under selection, predicting the effect of population disturbances, or modeling gene flow. This paper examines the detailed global population structure of Arabidopsis thaliana. Using a set of 5,707 plants collected from around the globe and genotyped at 149 SNPs, we show that while A. thaliana as a species self-fertilizes 97% of the time, there is considerable variation among local groups. This level of outcrossing greatly limits observed heterozygosity but is sufficient to generate considerable local haplotypic diversity. We also find that in its native Eurasian range A. thaliana exhibits continuous isolation by distance at every geographic scale without natural breaks corresponding to classical notions of populations. By contrast, in North America, where it exists as an exotic species, A. thaliana exhibits little or no population structure at a continental scale but local isolation by distance that extends hundreds of km. This suggests a pattern for the development of isolation by distance that can establish itself shortly after an organism fills a new habitat range. It also raises questions about the general applicability of many standard population genetics models. Any model based on discrete clusters of interchangeable individuals will be an uneasy fit to organisms like A. thaliana which exhibit continuous isolation by distance on many scales

    hCALCRL mutation causes autosomal recessive nonimmune hydrops fetalis with lymphatic dysplasia

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    We report the first case of nonimmune hydrops fetalis (NIHF) associated with a recessive, in-frame deletion of V205 in the G protein–coupled receptor, Calcitonin Receptor-Like Receptor (hCALCRL). Homozygosity results in fetal demise from hydrops fetalis, while heterozygosity in females is associated with spontaneous miscarriage and subfertility. Using molecular dynamic modeling and in vitro biochemical assays, we show that the hCLR(V205del) mutant results in misfolding of the first extracellular loop, reducing association with its requisite receptor chaperone, receptor activity modifying protein (RAMP), translocation to the plasma membrane and signaling. Using three independent genetic mouse models we establish that the adrenomedullin–CLR–RAMP2 axis is both necessary and sufficient for driving lymphatic vascular proliferation. Genetic ablation of either lymphatic endothelial Calcrl or nonendothelial Ramp2 leads to severe NIHF with embryonic demise and placental pathologies, similar to that observed in humans. Our results highlight a novel candidate gene for human congenital NIHF and provide structure–function insights of this signaling axis for human physiology
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