Metals in proteins from sulphate-reducing bacteria: adenylate kinase and ATP sulfurylase. Proteins containing cobalt, zinc, iron (II) ions

A Thesis submitted at the Faculty Science and Technology of the New University of Lisbon for a degree in Doctor of Philosophy in Biochemistry with specialization in Physical Biochemistry(fellowship BD SFRH/BD/24744/05)- Foundation for Science and Technolog

THE INFLUENCE OF FOREIGN BANK ENTRY ON THE DEVELOPMENT OF REGIONAL FINANCIAL MARKETS

Intensive international activity of banks caused by fairly recently lifted financial restrictions in many countries has been a subject ofgreat scientific interest ever since. The article describes various short-term consequences of foreign bank penetration in the financialmarkets of some of the regions of the world. The authors pay specific attention to the reasons and modes of foreign bank entry inemerging market and transition market economies as well as to the differences in the impact of such entry on the stability and efficiencyof financial systems and economies of the countries of Asia, Latin America, Central and Eastern Europe and Russia. Researchmethods: systemic, comparative and logical analysis.KEYWORDS: foreign bank entry, emerging market economies, bank competition, banking sector stability

Comparative Analysis of B-Cell Receptor Repertoires Induced by Live Yellow Fever Vaccine in Young and Middle-Age Donors

Age-related changes can significantly alter the state of adaptive immune system and often lead to attenuated response to novel pathogens and vaccination. In present study we employed 5′RACE UMI-based full length and nearly error-free immunoglobulin profiling to compare plasma cell antibody repertoires in young (19–26 years) and middle-age (45–58 years) individuals vaccinated with a live yellow fever vaccine, modeling a newly encountered pathogen. Our analysis has revealed age-related differences in the responding antibody repertoire ranging from distinct IGH CDR3 repertoire properties to differences in somatic hypermutation intensity and efficiency and antibody lineage tree structure. Overall, our findings suggest that younger individuals respond with a more diverse antibody repertoire and employ a more efficient somatic hypermutation process than elder individuals in response to a newly encountered pathogen

Purification, crystallization and preliminary X-ray diffraction analysis of adenosine triphosphate sulfurylase (ATPS) from the sulfate-reducing bacterium Desulfovibrio desulfuricans ATCC 27774

Native zinc-containing ATP sulfurylase from D. desulfuricans ATCC 27774 was purified to homogeneity and crystallized. Diffraction data were collected to 2.5 Å resolution