33 research outputs found
SU-8 based microprobes with integrated planar electrodes for enhanced neural depth recording
Catalase Activity in Leaves and Cotyledons During Plant Development and Senescence1)1) Part X of the series "Studies on Leaf Senescence". Supported in part by a Grant from the Council of Scientific and Industrial Research, Government of India to D.M.
Suspected malignancy in the cervical spine and abscessing dermatitis - 20 years to find the right diagnosis
Microprobe array with low impedance electrodes and highly flexible polyimide cables for acute neural recording
This paper reports on a novel type of silicon-based microprobes with linear, two and three dimensional (3D) distribution of their recording sites. The microprobes comprise either single shafts, combs with multiple shafts or 3D arrays combining two combs with 9, 36 or 72 recording sites, respectively. The electrical interconnection of the probes is achieved through highly flexible polyimide ribbon cables attached using the MicroFlex Technology which allows a connection part of small lateral dimensions. For an improved handling, probes can be secured by a protecting canula. Low-impedance electrodes are achieved by the deposition of platinum black. First in vivo experiments proved the capability to record single action potentials in the motor cortex from electrodes close to the tip as well as body electrodes along the shaft
Toward Automated Electrode Selection in the Electronic Depth Control Strategy for Multi-unit Recordings
Multi-electrode arrays contain an increasing number of electrodes.
The manual selection of good quality signals among hundreds of electrodes
becomes impracticable for experimental neuroscientists. This increases the need
for an automated selection of electrodes containing good quality signals. To
motivate the automated selection, three experimenters were asked to assign
quality scores, taking one of four possible values, to recordings containing
action potentials obtained from the monkey primary somatosensory cortex and
the superior parietal lobule. Krippendorff’s alpha-reliability was then used to
verify whether the scores, given by different experimenters, were in agreement.
A Gaussian process classifier was used to automate the prediction of the signal
quality using the scores of the different experimenters. Prediction accuracies of
the Gaussian process classifier are about 80% when the quality scores of
different experimenters are combined, through a median vote, to train the
Gaussian process classifier. It was found that predictions based also on firing
rate features are in closer agreement with the experimenters’ assignments than
those based on the signal-to-noise ratio alone.status: publishe