12 research outputs found
The development and validation of a scoring tool to predict the operative duration of elective laparoscopic cholecystectomy
- Author
- Aawsaj Yousif
- Abayomi Michael
- Acharya Vikas
- Aggarwal Smeer Kumar
- Ahmad Anwar
- Ahmed Irfan
- Ahmed Jamil
- Ahmed Javed
- Ahmed Talat
- Ainley Paul
- Akhtar Mansoor
- Al Amari Khalid
- Al-Abed Yahya A.
- Al-Akash Musallam
- Al-Bahrani Ahmed Z.
- Al-Khyatt Waleed
- Al-Muhktar Ahmed
- Al-Sarireh Bilal
- Al-Taan Omer
- Alagaratnam Swethan
- Alam Imran
- Alberts Justin
- Alderson Derek
- Aldridge Roland C.
- Aleksandrov Danail
- Ali Haythem
- Ali Shahda
- Amin Khalid
- Andrew David R.
- Appleton Shaun
- Arhi Chanpreet
- Aroori Somaiah
- Aryal Kamal
- Asad Mehek
- Aseem Rabiya
- Asprou Fotini M.
- Awan Altaf
- Ayaani Soofiyah
- Aymon null
- Babu Benoy I.
- Bajwa Dalvir S.
- Bajwa Farrukh M.
- Baker Andrew L.
- Balfe Paul
- Ball William R.
- Ballance Laura
- Banwell Victoria
- Barnes James
- Barrie Jenifer
- Bartlett Francis
- Basheer Mohammed
- Bashir Gareth
- Basra Melvinder
- Basu Sanjoy
- Basynat Pradeep
- Batt Jeremy
- Bausbacher Harald
- Bawa Sadiq
- Beasley William D.
- Belding Rowena
- Bellini Maria Irene
- Bennett Stephen P.
- Bhandari Santosh
- Bharamgoudar Reshma
- Bhattacharya Vish
- Blane Christine
- Blazeby Jane M.
- Boal Matthew
- Boddy Alexander
- Boland Michael
- Bond-Smith Giles
- Booth Michael I.
- Borowski David W.
- Bowen Laura
- Boyce Kathryn M.
- Boyd Alan T.
- Bradley Donal
- Bradley Neil
- Brennan Stephen
- Brett Daniel
- Broadhurst Jack
- Brooke Eleanor
- Brown Timothy H.
- Bryant Alice
- Buchan Joanna
- Bullen Naomi
- Bunnell Catherine
- Bunting David M.
- Burke Paul
- Byrne James P.
- Byrnes Colman K.
- Campbell William
- Carney Kate
- Carney Kate
- Carroll Paul
- Carter C. Ross
- Carter Nicholas C.
- Carty Nick
- Cassidy John T.
- Chambers Adam
- Chambers Alice
- Chambers Alice
- Chan Wei Ming
- Chang Jessica
- Charalabopoulos Alexandros
- Chauhan Neal
- Cheung Melanie
- Chhabra Alok
- Chishti Imran A.
- Chitre Vivek
- Choy Alfred
- Cieplucha Krzysztos
- Clements Joshua M.
- Coats Maria
- Cockbain Andrew J.
- Coe Peter O.
- Connelly Martin
- Cooke Fiachra
- Courtney Michael J.
- Cowley Jonathan B.
- Cross Keith S.
- Cuming Tamzin
- Cunha Pedro
- Dalgaty Faith
- Dar Farooq
- Date Ravindra
- Dave Rajiv V.
- Davey Phil
- Davies James
- Dawson Suzanne
- De Marchi Joshua A.
- de Siqueira Jonathan
- Deguara Jean
- Delisle Theo G.
- Dennison A. R.
- Derbyshire Laura
- Devoto Laurence
- Dhillon Ajit
- Diamond Tom
- Dickson-Lowe Richard
- Digney Ruairi
- Dindyal Shiva
- Dobbins Brian
- Doe Matthew
- Dorrian Emmet
- Doulias Triantafyllos
- Downing Justine
- Drake Benjamin
- Driscoll Peter J.
- Duke Diana
- Durkin Damien
- Dwerryhouse Simon J.
- DâCosta Conrad
- Ebdewi Hamdi
- Ebied Husam
- Eisawi Abdalla
- El-Dhuwaib Yesar
- El-Hasani Shamsi S.
- Elkheir Natalie
- Elmasry Mohamed
- Elsayed Mohammed
- Elshaer Mohamed
- Emesih Sophie
- Farag Sameh F.
- Farooq Ansar
- Farouk Marwan
- Fasih Tani
- Fawole Adeshina S.
- Fenwick Stephen
- Ferguson Graeme
- Ferris Paul
- Finch David
- Finch J. G.
- Finlay Ian
- Fleming Katie
- Fletcher Ted
- Fordham Imogen J.
- Forouzanfar Amir
- Forrest Craig R.
- Forster Luke
- Fothergill Laura
- Frame Richard J.
- Francombe James
- Frank Lucinda
- Fusai Guiseppe
- Galanopoulos Giorgios
- Gallagher Paul V.
- Garcea Giuseppe
- Gardner-Thorpe James
- Geoghegan Justin G.
- Geogloma Ileana
- Gerakopoulos Stratos
- Ghareeb Essam
- Ghazanfar Mudassar A.
- Gibson Simon
- Giles Mathew
- Giovinazzo Francesco
- Giwa Lola
- Goh Yan Li
- Gopalswamy Sivakumar
- Goscimski Andrzej
- Gossage James A.
- Gough Martin
- Gould Laura
- Gould Laura
- Grant Alan J.
- Gravante Gianpiero
- Griffiths Ewen
- Griffiths Ewen A.
- Gull Sadaf
- Gunasekera Rohan T.
- Gurung Kabita
- Guthrie Graeme J. K.
- Guy Finch J.
- Hafiz Shazia
- Halkias Constantine
- Hall Claire
- Hamady Zayed
- Hamdan Alhafidz
- Hamdan Mohammed F.
- Hamilton Emma
- Hancorn Kate
- Haque Manzarul
- Haque Samer Ul
- Hardy Thomas J.
- Hargreaves Anita
- Harilingam Mohan
- Harris Andrew
- Harrison Ewen
- Hawkins Helen
- Heath Jonathan
- Hebbar Madhusoodhana
- Henderson Lucy T.
- Henley Natasha
- Heshaishi Mohamed
- Hewes James
- Hewes James C.
- Heywood Nick
- Higgs Simon M.
- Hill Arnold D. K.
- Hindley Caroline
- Hirst Natalie A.
- Hisham Elzanati
- Ho Wei-Min
- Hoban Jennifer R.
- Hodgkins Kathryn A.
- Hodson James
- Holroyd David J.
- Hooks Gareth
- Hopwood Benjamin
- Hornby Steve T.
- Hornsby Jane
- Hosie Kenneth B.
- Hosie Kenneth B.
- Hossack Martin R.
- Hossain Tanvir
- Hoti Emir
- Hou David
- Hrycaiczuk Alex
- Hughes Michael
- Hunter David I.
- Hussain Abdulzahra A.
- Hussain Adnan
- Hussain Anwar
- Hussain Najam
- Iftikhar Syed Yusuf
- Iqbal Nusrat
- Iskandar Edrin
- Issa Eyad
- Ivanovski Ivan
- Jackson Andrew
- Jackson Claire
- Jafferbhoy Sadaf F.
- Jambulingam Periyathambi
- Jamdar Saurabh
- Jamel Sara
- Janeczko Adam
- Jaunoo Shameen
- Jayanthi Naga V. G.
- Jelley Clare
- Jennings Neil A.
- Joel Abraham
- Johnpulle Michelle A.
- Johnston Dorothy
- Johnstone Marianne
- Johnstone Marianne
- Joji Nikita
- Jones Claire
- Jones Elinor
- Jones Gareth H.
- Jones M. Angharad
- Jones Michael J.
- Jones Robert P.
- Jones Steven M.
- Kadhim Abbas
- Kadirkamanathan Sritharan
- Kallaway Charlotte
- Kanakala Venkatesh
- Kanavati Osama
- Kansal Nisheeth
- Kaptanis Sarantos
- Karavadra Babu
- Karim Lawen
- Karunakaran Priyadarssini
- Kaur Parminder
- Kausar Ambareen
- Kelly Michael E.
- Kendal Chris
- Kennedy David
- Kenny Ross
- Keogh Ken
- Khalil Ahmed M.
- Khan Amarah
- Khan Mohammad A.
- Khan Muhammad A. S.
- Khan Raja Basit
- Khan Shabuddin
- Khan Shahab
- Khawaja Amir
- Khawaja Zechan
- Khogali Elmoataz
- Kimble Adam
- Kinghorn Alison
- Kirkham Amanda J.
- Knight Benjamin
- Knight Katrina
- Kourkulos Michail
- Krysztopik Richard
- Kumar Pradeep
- Kynaston James
- Kyriakidis Dimitrios
- Lalla Kushik
- Lambert Joel
- Lammy Simon
- Lane Risha
- Larkin David
- Law Jennifer
- Lawther Roger
- Lazim Taha
- Lee Kathryn
- Lee Matthew
- Leeder Paul
- Lennon Hannah
- Lewis Michael
- Lim Henry C. C.
- Lim Pei J.
- Lindsay David
- Lloyd David
- Lo Christina
- Lodhia Joshil
- Longbotham David A.
- Loughlin Paula
- Lovett Bryony
- Luhmann Andreas
- Luther Ali Alison
- Lyons Emma M.
- Macano Christina A. W.
- MacArtney Matthew
- Macdonald Andrew
- Madanipour Suroosh
- Madbak Khaliel
- Madurska Marta
- Magee Conor J.
- Maguire Donal
- Maharaj Geta
- Majeed Ali
- Malcolm Cathy
- Malde Deep
- Malik Nabeela S.
- Mallik Mekhlola
- Mansour Sami
- Manu Mangta
- Manzelli Antonio
- Marriott Paul
- Martin Jack
- Martin Sean T.
- Martin Serena
- Marudanayagam Ravi
- Mason Denise
- Mathur Pawan
- Mawhinney Abi
- Mbuvi James
- McAree Barry
- McCain Stephen
- McCallum Iain J. D.
- McClarey Andrew
- McCune Ken
- McDermott Frank
- McEntee Gerry P.
- McGlone Emma R.
- McGuigan Andrew
- McIlmunn Colin
- McKay Damian
- McKenzie Stephen
- McNair Angus G. K.
- Mealy Ken
- Menzies Donald
- Mercer Stuart J.
- Milburn James
- Mirza Ahmed K.
- Mirza Darius
- Miu Victor
- Mockford Justine Downing Katherine A.
- Mohamed Sarah
- Mohan Helen M.
- Mok Kam Wa Jessica
- Monk David
- Morcous Paul
- Morrison Tamsin E. M.
- Mothe Bhavani Sidhartha
- Mowbray Nicholas
- Mozolowski Kirsty L.
- Mukherjee Dipankar
- Murphy James O.
- Murtaza Ghulam
- Nally Deirdre M.
- Napetti Sara
- Nassar Ahmad H.
- Naumann David
- Nedujchelyn Yuwaraja
- Needham Paul J.
- Newton Katy
- Newton Richard C.
- Ngu Wee Sing
- Nicholson Gary A.
- Nicholson James
- Nicholson James A.
- Nicol Laura
- Nicolay Christopher R.
- Nieto Tom
- Nijjar Rajwinder S.
- Nilsen-Nunn April
- Nilsson Frida
- Noble Fergus
- Nofal Emma
- Noor Nigel
- Nunes Quentin M.
- Obeidallah Mohd Rami
- Ogedegbe Arikoge
- Old Oliver J.
- Orchard Philippa
- Orizu Mavis N.
- OâDwyer Patrick
- OâNeill Maeve A.
- OâNeill Stephen
- OâReilly Derek A.
- Oâshea Kathryn M.
- OâSullivan Adrian W.
- Packer Jessica R.
- Padwick Robert
- Pannu Arslan
- Panteleimonitis Sofoklis
- Parappally Ciny P.
- Parmar J.
- Pasquali Sandro
- Patel Abhilasha
- Patel Krashna
- Patel Shakira
- Pati Pradeep
- Pearce Belinda
- Pearson Katherine L.
- Peirce Colin
- Pellen Mike
- Peter Mark B.
- Peterson Mark
- Pezzuto Roberto
- Photi Evangelos
- Phull Manraj
- Pinho-Gomes Ana C.
- Pollock Sarah
- Popplewell Matthew
- Pore Naresh
- Porter Jonathan
- Prasad Abheesh R.
- Prasad Raj
- Preston Shaun R.
- Preziosi Giuseppe
- Prince Sarah
- Psica Alicja
- Puig Sonia
- Puntis Daniel J.
- Puri Yogesh
- Qandeel Haitham
- Rabie Mohamed
- Radwan Rami
- Rae David M.
- Rahman Saquib
- Rajaganeshan Rajasundaram
- Rajendran Ilayaraja
- Ramage Michael I.
- Rao Sudhindra T. V.
- Rate Anthony J.
- Raza Soulat
- Read Edward
- Reddy Marcus
- Reece-Bolton Obuobi
- Reed Joanna
- Reid Alistair
- Rengifo Carla
- Rhys Thomas
- Richards Colin H.
- Riera Manel
- Ritchie Judith
- Robb William
- Roberts Geoffrey P.
- Robinson Sarah
- Robinson Steven J.
- Robinson Stuart
- Rodriguez Dan
- Rodriguez Daniel Urriza
- Roebuck Amanda
- Rogers Paul N.
- Rolph Rachel C.
- Roy Sudipta
- Rutherford Claire L.
- Sadat Mohammed M.
- Sakai Naomi
- Sampat Keerthika
- Samuel Nehemiah
- Sarmah Piyush B.
- Sarvananthan Kas
- Sarveswaran Janahan
- Satheesan Steve
- Saunders Michael
- Sayegh Mazin
- Segaran Ashvina
- Sekhar Hema
- Sen Gourab
- Seymour Keith
- Shabo Wael
- Shah Nayab
- Shah Reena
- Shahin Yousef
- Sheel Andrea R. G.
- Shenoy Hrishikesh
- Shetty Vinutha
- Shier David
- Shingler Guy M.
- Shiwani Muhammad Hanif
- Shrestha Ashish Kiran
- Siddiqi Najaf
- Siddiqui Midhat N.
- Siddiqui Zohaib
- Sillo Toritseju O.
- Silva Michael
- Simpson Duncan J.
- Singh Shailendra
- Singh-Ranger Deepak
- Sinha Sidhartha
- Skelly Brendan L.
- Slavin John P.
- Slawinski Corinna
- Sloane Jake
- Smith Stella R.
- Smith Stella R.
- Sonsale Aniket
- Spearman John
- Spence Gary
- Spreadborough Philip
- Spreadborough Philip
- Starmer Benjamin Z.
- Stevenson Thomas E. J.
- Stewart Duncan J.
- Stirland E.
- Subramanium Dhivya
- Sufi Pratik A.
- Sukha Anisha
- Sutcliffe Robert
- Suttie Stuart
- Sutton Cherith M. L. R.
- Szentpali Karoly
- Tang Cheuk-Bong
- Tanner Nicola
- Tate Sophie
- Tayeh Salim
- Taylor Christopher
- Taylor Greg W.
- Teasdale Rebecca L.
- Templeton Alexa
- Terrace John
- Thakkar Rohan
- Thomas George
- Thompson Ronald L. E.
- Tilston Michael P.
- Toh Simon K. C.
- Tolofari Sotonye
- Tomlinson Mark A.
- Trevatt Alexander E. J.
- Trotter Martin
- Tsang Andrew
- Tsavellas George
- Tuck Liz
- Turner Paul
- Tutton Matthew G.
- Ullah Muhammad Fahad
- Upchurch Emma A.
- Urbonas Tomas
- Varghase Joseph
- Vass David G.
- Vaughan Elizabeth M.
- Vijay Vardhini
- Vijayan Deepak
- Vijayanand Dhakshinamoorthy
- Villatoro Eduardo
- Virupaksha Suvi
- Vitone Louis J.
- Vohra Ravinder S.
- Wadley Martin
- Wainwright Denise
- Wajed Saj
- Wallace Tom
- Wardle Stacy
- Warren Conor
- Watkin Helen
- Watson Angus J. M.
- Watson Nicholas F.
- Wayman John
- Weaver Simon
- Weber Beatrix
- Weber Beatrix
- Weerasinghe Chamindri
- Welbourn Hannah
- Wheatley Kevin
- White Timothy J.
- Wijetunga Imeshi
- Wild Jonathan R. L.
- Wilkinson Marc D.
- Williams Sophie V.
- Williamson Tracey K.
- Willson Peter D.
- Wilson Michael S. J.
- Wilson Timothy R.
- Winter Des C.
- Winter Hannah
- Wood Christopher P. J.
- Wood Peter
- Wood Simon
- Woodman Thomas
- Yahya Salama
- Yao Caroline
- Yeldham Geoffrey
- Yoganathan Thusidaran
- Youssef Haney
- Zafar Sara
- Zafrani Zakhi
- Zarsadias Prizzi
- Zeeshan Saquib
- Zhang Catherine
- Ziprin Paul
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
Background: The ability to accurately predict operative duration has the potential to optimise theatre efficiency and utilisation, thus reducing costs and increasing staff and patient satisfaction. With laparoscopic cholecystectomy being one of the most commonly performed procedures worldwide, a tool to predict operative duration could be extremely beneficial to healthcare organisations.
Methods: Data collected from the CholeS study on patients undergoing cholecystectomy in UK and Irish hospitals between 04/2014 and 05/2014 were used to study operative duration. A multivariable binary logistic regression model was produced in order to identify significant independent predictors of long (>â90 min) operations. The resulting model was converted to a risk score, which was subsequently validated on second cohort of patients using ROC curves.
Results: After exclusions, data were available for 7227 patients in the derivation (CholeS) cohort. The median operative duration was 60 min (interquartile range 45â85), with 17.7% of operations lasting longer than 90 min. Ten factors were found to be significant independent predictors of operative durations >â90 min, including ASA, age, previous surgical admissions, BMI, gallbladder wall thickness and CBD diameter. A risk score was then produced from these factors, and applied to a cohort of 2405 patients from a tertiary centre for external validation. This returned an area under the ROC curve of 0.708 (SEâ=â0.013, pââ90 min increasing more than eightfold from 5.1 to 41.8% in the extremes of the score.
Conclusion: The scoring tool produced in this study was found to be significantly predictive of long operative durations on validation in an external cohort. As such, the tool may have the potential to enable organisations to better organise theatre lists and deliver greater efficiencies in care
Methods of screening apricot fruit for resistance to brown rot caused by Monilinia
- Author
- Publication venue
- 'CSIRO Publishing'
- Publication date
- 01/01/2004
- Field of study
Compounds alone and in combination with yeasts to control Colletotrichum acutatum in apples
- Author
- A El-Ghaouth
- A Ippolito
- AL Jones
- AR Biggs
- B Scherm
- BH Hall
- BJ Smith
- C Nunes
- DM Eastburn
- E Timewell
- GenStat Committee
- GenStat Committee
- I. P. Shamini Pushparajah
- J Lodder
- K Everett
- KD Hickey
- Kerry R. Everett
- Kirsty S. H. Boyd-Wilson
- KR Everett
- KR Everett
- KSH Boyd-Wilson
- KSH Boyd-Wilson
- M Rahman
- M Zulfiqar
- MG Kenward
- Monika Walter
- NA Peres
- OE Timudo-Torrevilla
- P McCullagh
- Peter A. Alspach
- PR Johnston
- R Payne
- RJ McLaughlin
- RM Beresford
- Ruth C. Butler
- S Freeman
- U Damm
- WS Conway
- WS Conway
- Y Lee
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index
- Author
- Abecasis G. R.
- Absher D.
- Adair L. S.
- Adan R.
- Adan Roger A. H.
- Alavere H.
- Albrecht E.
- Albrecht E.
- Alexander Graeme
- Alfredsson Lars
- Alizadeh B.
- Amin N.
- Amin N.
- Amouyel P.
- Anderson Carl A.
- Ando Tetsuya
- Andreassen Ole A.
- Ang W.
- Antel J.
- Aschauer Harald
- Aspelund T.
- Asselbergs F. W.
- Assimes T. L.
- Atalay M.
- Atalay M.
- Attwood A. P.
- Baker Jessica H.
- Balmforth A. J.
- Bandinelli S.
- Barrett Jeff C.
- Barrett Jeffrey C.
- Barroso I.
- Barroso I.
- Basart H.
- Beilby J.
- Bencko Vladimir
- Benke K.
- Berenson G. S.
- Berg J.
- Bergen A. W.
- Bergen Andrew W.
- Bergen N.
- Bergmann S.
- Berndt S. I.
- Berrettini W.
- Berrettini Wade
- Berrettini Wade H.
- Berry D. J.
- Bierut L. J.
- Blackburn H.
- Blackburn Hannah
- Blackwood D.
- Boehm B. O.
- Boehnke M.
- Boerwinkle E.
- Boerwinkle E.
- Boezen H. M.
- Boni Claudette
- Bonnycastle L. L.
- Boomsma D. I.
- Boomsma D. I.
- Boraska Perica V.
- Borecki I. B.
- Boyd H. A.
- Bradfield J. P.
- Bragg-Gresham J. L.
- Brambilla P.
- Brandt Harry
- Brandys M.
- Brandys Marek K.
- Breen Gerome
- Bruinenberg M.
- Bruinenberg M.
- Bruson Alice
- Bulik C. M.
- Bulik Cynthia M.
- Bulik Cynthia M.
- Bulik Cynthia M.
- Burghardt Roland
- Buring J. E.
- Busonero F.
- Byrne E. M.
- BĂŒhren Katharina
- BĂŒltmann U.
- Cadby G.
- Campbell H.
- Campbell H.
- Campbell H.
- Carlberg Laura
- Caulfield M. J.
- Cavanagh J.
- Chanock S. J.
- Chanock S. J.
- Charoen P.
- Chasman D. I.
- Chasman D. I.
- Chen W.
- Chen Wei-Min
- Children's Hospital of Philadelphia/Price Foundation
- Chines P. S.
- Cichon Sven
- Clair D. S.
- Clementi Maurizio
- Cohen-Woods Sarah
- Coin L.
- Collier D.
- Collier David A.
- Collier David A.
- Collins F. S.
- Cone Roger D.
- Conlon Peter J.
- Connell J.
- Connell J. M.
- Connor M.
- Cookson W.
- Cooper C.
- Cornelis M. C.
- Corre T.
- Couper D.
- Cousminer D. L.
- Cousminer D. L.
- Coviello A. D.
- Crawford Steve
- Crisponi L.
- Croteau-Chonka D. C.
- Crow Scott
- Cunningham-Burley S.
- Cupples L.
- Cusi D.
- d'Adamo P.
- Dackor Jennifer
- Danner Unna N.
- Das S.
- Davey Smith G.
- Davis O. S.
- Davis Oliver S. P.
- Day F. R.
- de Bakker P.
- de Boer R.
- de Faire U.
- de Faire U.
- de Geus E. J.
- de Kove Carolien
- de Vegt F.
- de Zwaan M.
- de Zwaan Martina
- Deary I.
- Dedoussis G. V.
- Dedoussis G. V.
- Dedoussis George
- Degortes Daniela
- Dei M.
- Deloukas P.
- Deloukas P.
- Demerath E. W.
- den Heijer M.
- DeSocio Janiece E.
- Di Blasio A. M.
- Dick Danielle M.
- Dikeos Dimitris
- Dimitriou M.
- Dina Christian
- Ding Bo
- Dmitrzak-Weglarz Monika
- Docampo Elisa
- Dominiczak A.
- Dominiczak Anna
- Duncanson Audrey
- Döring A.
- Easton D. F.
- Econs M. J.
- Edkins S.
- Edkins Sarah
- Egberts K. M.
- Egberts Karin
- EGG
- Ehrlich S.
- Ehrlich Stefan
- Eiriksdottir G.
- Eklund N.
- Elks C. E.
- Elliott P.
- Ellis P.
- Emilsson V.
- Erdmann J.
- Eriksson J.
- Eriksson J. G.
- EscaramĂ GeĂČrgia
- Esko T.
- Esko T.
- Esko TÔnu
- Espeseth Thomas
- Estivill X.
- Estivill Xavier
- Estrada K.
- Evans D. M.
- Evans D. M.
- Fall T.
- Farmer Anne
- Farrall M.
- Favaro Angela
- Feenstra B.
- Feenstra B.
- Feitosa M. F.
- FernĂĄndez-Aranda Fernando
- Ferrario M. M.
- Ferreira T.
- Ferreli L.
- FerriĂšres J.
- Ferrucci L.
- Fichter Manfred M.
- Finan Chris
- Fischer K.
- Fischer Krista
- FitzPatrick B.
- Flexeder C.
- Floyd James A. B.
- Floyd James A. B.
- Folsom A. R.
- Ford I.
- Foretova Lenka
- Foroud T.
- Forzan Monica
- Fox C. S.
- Franceschini N.
- Franke L.
- Franke L.
- Franklin C. S.
- Franklin Christopher S.
- Franklin Christopher S.
- Franks P. W.
- Frau F.
- Frayling T.
- Frayling T.
- Freathy R. M.
- Froguel P.
- Föcker M.
- Gaborieau Valerie
- Gaillard R.
- Gallinger Steven
- Gambaro Giovanni
- Ganna A.
- Garcia M.
- Gasparini P.
- GCAN
- Gejman P. V.
- Geleijnse M.
- Geller F.
- Geller F.
- Gentilini D.
- Gertz R.
- GIANT
- Gieger C.
- Gieger C.
- Giegling Ina
- Gillman M.
- Gillman Mathew
- Goel A.
- Goh L. K.
- Gonidakis Fragiskos
- Gorwood Philip
- Grallert H.
- Grant S. F.
- Grant S. F. A.
- Gratacos Monica
- Grau A.
- Gray Emma
- Groen-Blokhuis M.
- Groop L. C.
- Grönberg H.
- Gudbjartsson D. F.
- Gudnason V.
- Gudnason V.
- Guo Y.
- Guo Yiran
- Gustafsson S.
- Guxens M.
- Gyllensten U.
- Haddow G.
- Hadley D.
- Hakonarson H.
- Hakonarson H.
- Hakonarson Hakon
- Hall A. S.
- Hall P.
- Hall P.
- Halmi Katherine A.
- Hamsten A.
- Hankinson S. E.
- Haritunian T.
- Harris T. B.
- Harris T. B.
- Harst P. V.
- Hartikainen A. L.
- Hattersley A. T.
- Hauser Joanna
- Haworth C. M.
- Hayward C.
- Hayward C.
- He C.
- Heard-Costa N. L.
- Heath A. C.
- Heath A. C.
- Hebebrand J.
- Hebebrand J.
- Hebebrand J.
- Hebebrand Johannes
- Heid I. M.
- Heid I. M.
- Heinrich J.
- Helder Sietske
- Hellard Stephanie Le
- Hendriks Judith
- Hengstenberg C.
- Herms Stefan
- Hernandez D. G.
- Herpertz-Dahlmann B.
- Herpertz-Dahlmann Beate
- Herzog W.
- Herzog Wolfgang
- Hicks A. A.
- Hill Adrian
- Hillege H.
- Hilliard Christopher E.
- Hingorani A.
- Hinney A.
- Hinney A.
- Hinney A.
- Hinney Anke
- Hirschhorn J. N.
- Hirschhorn J. N.
- Hocher B.
- Hofman A.
- Hofman A.
- Holloway J. W.
- Holst C.
- Homuth G.
- Horikoshi M.
- Hottenga J. J.
- Hottenga J. J.
- Hottenga J. J.
- Hovingh K. G.
- Hu F. B.
- Hu F. B.
- Hu Y. J.
- Huckins Laura M.
- Hudson James I.
- Huemer Julia
- Huffman J. E.
- Huikari V.
- Hunt S. E.
- Hunt Sarah E.
- Hunter D.
- Hunter D. J.
- Hveem K.
- Hypponen E.
- Hyppönen E.
- Iezebrink Kirsty
- Illig T.
- Illig T.
- Imgart Hartmut
- Ingelsson E.
- Inoko Hidetoshi
- Iribarren C.
- Iñiguez C.
- Jackson A. U.
- Jackson C.
- Jacobs K. B.
- Jaddoe V. W.
- Jall S.
- Janout Vladimir
- Jansson J. O.
- Jarick I.
- Jarvelin M. R.
- Jarvelin M. R.
- Jiménez-Murcia Susana
- Johansson A.
- Johnson A. D.
- Johnson Craig
- Johnson T.
- Jula A.
- Julia Antonio
- Justice A. E.
- JĂ€rvelin M. R.
- Jöckel K. H.
- Kaakinen M.
- Kalsi Gursharan
- Kanoni S.
- Kaplan Allan S.
- Kaplan Allan S.
- Kaplan R. C.
- Kaprio Jaakko
- Karasik D.
- Karhunen Leila
- Karpe F.
- Karwautz Andreas
- Kas Martien J. H.
- Kathiresan S.
- Kaye W.
- Kaye Walter
- Kee F.
- Keel Pamela
- Keinanen-Kiukaanniemi S. M.
- Kennedy James L.
- Kerr S.
- Keski-Rahkonen Anna
- Kesselmeier M.
- Khaw K. T.
- Khaw K. T.
- Kiel D. P.
- Kiemeney L. A.
- KilpelÀinen T. O.
- KilpelÀinen T. O.
- Kirin M.
- Kivimaki M.
- Klareskog Lars
- Kleber M. E.
- Klump Kelly L.
- Klump Kelly L.
- Knudsen Gun Peggy S.
- Koeleman Bobby P. C.
- Koenig W.
- Kolcic I.
- Koller D. L.
- Komaki Gen
- Koppelman G.
- Koubek Doris
- Kowgier M.
- Kraft P.
- Kraja A. T.
- Kristiansson K.
- Kuh D.
- Kumari M.
- Kutalik Z.
- Kutalik Z.
- Kuulasmaa K.
- Kuusisto J.
- KÀhönen M.
- König I. R.
- Laakso M.
- Laitinen J. H.
- Lakka H. M.
- Lakka T. A.
- Lakka T. A.
- Lamina C.
- Lange L. A.
- Langenberg C.
- Langford Cordelia
- Launer L. J.
- Launer L. J.
- Laven J. S.
- Lawlor D. A.
- Lecoeur C.
- Lee S. H.
- LehtimÀki T.
- LehtimÀki T.
- Levinson D. F.
- Levitan Robert D.
- Levy D.
- Lewin A.
- Lewis Cathryn M.
- Li Dong
- Li G.
- Li S.
- Liang L.
- Lichtenstein Paul
- Lilenfeld Lisa
- Lin D. Y.
- Lin P.
- Lind L.
- Lindgren C.
- Lindgren C. M.
- Lindi V.
- Lindsay R.
- Lindström J.
- Lissowska Jolanta
- Liu J.
- Liu J.
- Liuzzi A.
- Logan Darren W.
- Lokki M. L.
- Loos R. J.
- Loos R. J.
- Lord Graham
- Lorentzon M.
- Luan J.
- Lundervold Astri
- Lunetta K. L.
- Madden P. A.
- Maggi R.
- Magistretti Pierre
- Magnusson P. K.
- Magnusson P. K.
- Maj Mario
- Mangino M.
- Mangino M.
- Manunta P.
- Marek D.
- Marongiu M.
- Marsal Sara
- Marsh J.
- Martaskova Debora
- Martin N. G.
- Martin N. G.
- Mateo Leach I.
- Mattingsdal Morten
- Maxwell Alexander P.
- McArdle P. F.
- McArdle W. L.
- McArdle W. L.
- McArdle Wendy L.
- McCarthy M. I.
- McCarthy M. I.
- McGilchrist M.
- McGinnis Ralph
- McGuffin Peter
- McIntyre D.
- McKnight B.
- Medina-Gomez C.
- Medland S. E.
- Melbye M.
- Melbye M.
- Merl Elisabeth
- Metspalu A.
- Metspalu A.
- Metspalu Andres
- Meulenbelt Ingrid
- Meyre D.
- Middeldorp C.
- Mihailov E.
- Milani L.
- Millwood I.
- Min J. L.
- Mitchell James
- Moffatt M.
- Mohlke K. L.
- Mohlke K. L.
- Monda K. L.
- Monteleone Palmiero
- Montgomery G. W.
- Montgomery G. W.
- Mook-Kanamori D. O.
- Mooser V.
- Mooser V.
- Morgan Linda
- Morris A.
- Morris A. D.
- Morris A. P.
- Morton R.
- Muir W.
- Munroe P. B.
- Murabito J. M.
- Murray A.
- Murray G.
- Murray J. C.
- Murray J. C.
- Murray S. S.
- Musk A. W.
- MĂ€gi R.
- MĂ€nnik Katrin
- MĂ€rz W.
- MĂŒhleisen T. W.
- MĂŒller T. D.
- MĂŒller-Nurasyid M.
- Nalls M. A.
- Narisu N.
- Navarro P.
- Navis G.
- Navis G.
- Navratilova Marie
- Neale B. M.
- Nelis M.
- Nengut-Gumuscu Suna
- Ness A. R.
- Ngwa J. S.
- Nicholson G.
- Nieminen M. S.
- Nivard M.
- NjĂžlstad I.
- Nohr E. A.
- Nohr E. A.
- Nolte I. M.
- North K. E.
- Northstone K.
- Ntalla I.
- Ntalla Ioanna
- O'Connell J. R.
- O'Reilly P. F.
- O'Toole Julie K.
- Ohlsson C.
- Oken E.
- Oldehinkel A. J.
- Ong K. K.
- Ong K. K.
- Ong K. K.
- Oostra B. A.
- Oostra B. A.
- Ophoff Roel A.
- Ormel J.
- Ouwehand W. H.
- Ouwehand Willem H.
- Padyukov Leonid
- Palmer C.
- Palmer C. N.
- Palmer L. J.
- Palmer L. J.
- Palmer L. J.
- Palotie A.
- Palotie A.
- Palotie Aarno
- Panoutsopoulou K.
- Pantel Jacques
- Papezova Hana
- Pararajasingham J.
- Parker A. N.
- Paré G.
- Paternoster L.
- Pawitan Y.
- Peacock M.
- Pearson E. R.
- Pechlivanis S.
- Peden J. F.
- Pedersen N.
- Pedersen N. L.
- Pell J.
- Peltonen L.
- Peltonen Leena
- Peltonen Leena
- Pennell C. E.
- Pennell C. E.
- Penninx B.
- Perica Vesna Boraska
- Perola M.
- Perry J. R.
- Peters A.
- Peters M. J.
- Pharoah P.
- Philp A.
- Pinto Dalila
- Plotnicov Kathy
- Plump A. S.
- Polasek O.
- Polasek O.
- Porcu E.
- Porteous D.
- Porteous M.
- Postma D.
- Potter Simon
- Pourcain B. S.
- Pouta A.
- Pouta A.
- Power C.
- Power C.
- Pramstaller P. P.
- Preuss M.
- Price Foundation Collaborative Group
- Price T. S.
- Procter R.
- Prokopenko I.
- Prokopenko I.
- Province M. A.
- Psaty B. M.
- PĂŒtter C.
- Qi L.
- Rabionet Raquel
- Radhakrishnan A.
- Raevuori-Helkamaa Anu
- Rafnar T.
- Raitakari O.
- Raitakari O. T.
- Rajewski Andrzej
- Ralston S.
- Ramoz Nicolas
- Randall J. C.
- Rauramaa R.
- Rayner N. William
- Reichborn-Kjennerud Ted
- Reid D.
- Reinvang Ivar
- Rendon A.
- Rice J. P.
- Rich Stephen S.
- Ridker P. M.
- Ridker P. M.
- Ring S. M.
- Ring Susan M.
- Ripatti S.
- Ripatti Samuli
- Ritchie Graham R. S.
- Rivadeneira F.
- Rivadeneira F.
- Roberts Marion
- Rodriguez A.
- Rose L. M.
- Rosmalen J.
- Rosmalen J. G.
- Rotondo Alessandro
- Rudan I.
- Rudan I.
- Rujescu Dan
- Rybakowski Filip
- Saaristo T. E.
- Sala C.
- Salem R. M.
- Salomaa V.
- Salomaa V.
- Samani N. J.
- Sambrook J. G.
- Sambrook Jennifer
- Sanders A. R.
- Sandford Richard N.
- Sanna S.
- Sanna S.
- Santonastaso Paolo
- Saramies J.
- Saw S. M.
- Schadt E. E.
- Scherag A.
- Scherag A.
- Scherag A.
- Scherag André
- Scherag Susann
- Scherer Stephen W.
- Schipf S.
- Schlessinger D.
- Schlessinger D.
- Schmidt Ulrike
- Schork N. J.
- Schork Nicholas J.
- Schosser Alexandra
- Schreiber S.
- Schreiber Stefan
- Schunkert H.
- Scuteri A.
- Sebert S.
- SegrĂš A. V.
- Sheerin Neil
- Shi J.
- Shin S. Y.
- Shuldiner A. R.
- Shungin D.
- Signorini S.
- Siitonen N.
- Simell O.
- Simpkin Douglas
- Sinisalo J.
- Sinnott R.
- Skrobek B.
- Slachtova Lenka
- Sladek Rob
- Slaets J.
- Slagboom P. Eline
- Slof-Op't Landt Margarita C. T.
- Slopien Agnieszka
- Smidt H.
- Smith A. V.
- Smith A. V.
- Smith B.
- Smith E. N.
- Snieder H.
- Snieder H.
- Soranzo N.
- Soranzo N.
- Soranzo Nicole
- Soranzo Nicole
- Southam Lorraine
- Sovio U.
- Sovio U.
- Spector T. D.
- Spector T. D.
- Speliotes E. K.
- Srinivasan S. R.
- Stancakova A.
- Stark K.
- Steen Vidar M.
- Stefansson K.
- Stefansson K.
- Steinthorsdottir V.
- Stephens J. C.
- Stephens Jonathan
- Stirrups K.
- Stolk L.
- Stolk R.
- Stolk R. P.
- Stolk R. P.
- Strachan D. P.
- Strachan D. P.
- Strachan D. P.
- Strachan David P.
- Strawbridge R. J.
- Streeten E. A.
- Strengman Eric
- Strober Michael
- Stumvoll M.
- Sulem P.
- Sullivan F.
- Sullivan Patrick F.
- Sunyer J.
- Surakka I.
- Sweetland M.
- Swertz M. A.
- Swift A. J.
- Szatkiewicz Jin P.
- Szeszenia-Dabrowska Neonila
- SĂžrensen T. I.
- SĂžrensen T. I.
- Taal H. R.
- Tachmazidou Ioanna
- Taico Chrysecolla
- Tammesoo M. L.
- Tenconi Elena
- Teo Y. Y.
- Teumer A.
- Theodoraki E. V.
- Thiering E.
- Thorand B.
- Thorleifsson G.
- Thornton Laura M.
- Thornton Laura M.
- Thorsteinsdottir U.
- Thorsteinsdottir U.
- Tiesler C.
- Tikkanen E.
- Timpson N. J.
- Toniolo D.
- Tortorella Alfonso
- Tozzi Federica
- Trace Sara E.
- Treasure Janet
- Treasure Janet
- Tregouet D. A.
- Tremoli E.
- Trip M. D.
- Tryggvadottir L.
- Tschöp M. H.
- Tsitsika Artemis
- Tsui K.
- Tuomilehto J.
- Tyrer J.
- Tyrer J.
- Tziouvas Konstantinos
- Tönjes A.
- Uda M.
- Uitterlinden A. G.
- Uitterlinden A. G.
- Uitterlinden A. G.
- Ulivi S.
- Ure J.
- Uusitupa M.
- ValcĂĄrcel B.
- van Beijsterveldt T.
- van Dam R. M.
- van der Harst P.
- van der Harst P.
- van der Klauw M.
- Van der Klauw M. M.
- van Duijn C. M.
- van Duijn C. M.
- van Elburg A.
- van Elburg Annemarie A.
- Van Furth Eric F.
- van Meurs J. B.
- van Meurs J. B.
- van Rossum L.
- Van Vliet-Ostaptchouk J. V.
- van Wingerden S. H.
- Vandenput L.
- Vannberg Frederik O.
- Vedantam S.
- Vermeulen S. H.
- Versini Audrey
- Via Maria La
- Viikari J.
- Virtamo J.
- Visscher P. M.
- Visser J. A.
- Vitart V.
- Volckmar A.-L.
- Vollenweider P.
- Vollenweider P.
- Waeber G.
- Waeber G.
- Wagner Gudrun
- Waite L. L.
- Wallaschofski H.
- Wang Z.
- Wareham N. J.
- Wareham N. J.
- Warrington M.
- Warrington N. M.
- Waterworth D. M.
- Watkins H.
- Watt G.
- Weedon M. N.
- Wheeler E.
- White S.
- Whittaker Pamela
- Wichmann H. E.
- Wichmann H.-
- Wichmann H.-Erich
- Widen E.
- Widen E.
- Widén E.
- Widén Elisabeth
- Wijmenga C.
- Wild S. H.
- Willemsen G.
- Willemsen G.
- Willemsen G.
- Willer C. J.
- Wilson J. F.
- Wilson J. F.
- Wilson J. F.
- Winkelmann B. R.
- Winkler T. W.
- Winkler T. W.
- Witteman J. C.
- Wolf R.
- Wolffenbuttel B.
- Wolffenbuttel B. H.
- Wong A.
- Wood A. R.
- Woodside D. Blake
- Workalemahu T.
- Wright A.
- Wright A. F.
- Wright A. F.
- WTCCC3
- Yaghootkar H.
- Yang J.
- Yilmaz Zeynep
- Young L.
- Zeggini E.
- Zeggini E.
- Zeggini Eleftheria
- Zeggini Eleftheria
- Zerwas Stephanie
- Zgaga L.
- Zhai G.
- Zhao J. H.
- Zhao J. H.
- Zhuang W. V.
- Zillikens M.
- Zipfel S.
- Zipfel Stephan
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 17/05/2016
- Field of study
The maintenance of normal body weight is disrupted in patients with anorexia nervosa (AN) for prolonged periods of time. Prior to the onset of AN, premorbid body mass index (BMI) spans the entire range from underweight to obese. After recovery, patients have reduced rates of overweight and obesity. As such, loci involved in body weight regulation may also be relevant for AN and vice versa. Our primary analysis comprised a cross-trait analysis of the 1000 single-nucleotide polymorphisms (SNPs) with the lowest P-values in a genome-wide association meta-analysis (GWAMA) of AN (GCAN) for evidence of association in the largest published GWAMA for BMI (GIANT). Subsequently we performed sex-stratified analyses for these 1000 SNPs. Functional ex vivo studies on four genes ensued. Lastly, a look-up of GWAMA-derived BMI-related loci was performed in the AN GWAMA. We detected significant associations (P-values <5 Ă 10â5, Bonferroni-corrected P<0.05) for nine SNP alleles at three independent loci. Interestingly, all AN susceptibility alleles were consistently associated with increased BMI. None of the genes (chr. 10: CTBP2, chr. 19: CCNE1, chr. 2: CARF and NBEAL1; the latter is a region with high linkage disequilibrium) nearest to these SNPs has previously been associated with AN or obesity. Sex-stratified analyses revealed that the strongest BMI signal originated predominantly from females (chr. 10 rs1561589; Poverall: 2.47 Ă 10â06/Pfemales: 3.45 Ă 10â07/Pmales: 0.043). Functional ex vivo studies in mice revealed reduced hypothalamic expression of Ctbp2 and Nbeal1 after fasting. Hypothalamic expression of Ctbp2 was increased in diet-induced obese (DIO) mice as compared with age-matched lean controls. We observed no evidence for associations for the look-up of BMI-related loci in the AN GWAMA. A cross-trait analysis of AN and BMI loci revealed variants at three chromosomal loci with potential joint impact. The chromosome 10 locus is particularly promising given that the association with obesity was primarily driven by females. In addition, the detected altered hypothalamic expression patterns of Ctbp2 and Nbeal1 as a result of fasting and DIO implicate these genes in weight regulation
Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index
- Author
- Adair L. S.
- Adan R.
- Adan Roger A. H.
- Alavere H.
- Albrecht E.
- Alexander Graeme
- Alfredsson Lars
- Amin N.
- Anderson Carl A
- Ando Tetsuya
- Andreassen Ole A
- Ang W.
- Antel J.
- Aschauer Harald
- Aspelund T.
- Atalay M.
- Baker Jessica H
- Bandinelli S.
- Barrett Jeff C
- Barrett Jeffrey C
- Barroso I.
- Bencko Vladimir
- Benke K.
- Berenson G. S.
- Bergen A. W.
- Bergen A. W.
- Bergen N.
- Bergmann S.
- Berrettini W.
- Berrettini Wade
- Berrettini Wade H.
- Berry D. J.
- Bierut L. J.
- Blackburn H.
- Blackburn Hannah
- Boerwinkle E.
- Boni Claudette
- Boomsma D. I.
- Boraska Perica V.
- Boyd H. A.
- Bradfield J. P.
- Brandt Harry
- Brandys M.
- Brandys Marek K
- Breen Gerome
- Bruson Alice
- Bulik C. M.
- Bulik C. M.
- Bulik Cynthia M
- Bulik Cynthia M
- Burghardt Roland
- Buring J. E.
- Busonero F.
- Byrne E. M.
- BĂŁÂŒhren Katharina
- Campbell H.
- Carlberg Laura
- Chanock S. J.
- Charoen P.
- Chasman D. I.
- Chen W.
- Chen Wei Min
- Christian Dina
- Cichon Sven
- Clementi Maurizio
- Cohen Woods Sarah
- Coin L.
- Collier D.
- Collier David A
- Collier David A
- Cone Roger D
- Conlon Peter J
- Cooper C.
- Cornelis M. C.
- Corre T.
- Couper D.
- Cousminer D. L.
- Cousminer D. L.
- Coviello A. D.
- Crawford Steve
- Crisponi L.
- Crow Scott
- D'Adamo P.
- Dackor Jennifer
- Danner Unna N
- Das S.
- Davey Smith G.
- Davis O. S.
- Davis Oliver S. P.
- de Faire U.
- de Geus E. J.
- de Kove Carolien
- De Zwaan M.
- de Zwaan Martina
- Dedoussis G. V.
- Dedoussis George
- Degortes Daniela
- Deloukas P.
- Demerath E. W.
- Desocio Janiece E
- Dick Danielle M
- Dikeos Dimitris
- Ding Bo
- Dmitrzak Weglarz Monika
- Docampo Elisa
- Dominiczak Anna
- Duncanson Audrey
- Dã¶ring A.
- Easton D. F.
- Econs M. J.
- Edkins Sarah
- Egberts K. M.
- Egberts Karin
- Ehrlich S.
- Ehrlich Stefan
- Eiriksdottir G.
- Elks C. E.
- Elliott P.
- Emilsson V.
- Eriksson J.
- Esko T.
- Esko Tã”nu
- Espeseth Thomas
- Estivill X.
- Estivill Xavier
- Evans D. M.
- Farmer Anne
- Favaro Angela
- Feenstra B.
- Feenstra B.
- FernĂÂĄndez Aranda Fernando
- Ferreli L.
- Ferrucci L.
- Fichter M. M.
- Finan Chris
- Fischer Krista
- Flexeder C.
- Floyd James A. B.
- Floyd James A. B.
- Folsom A. R.
- Foretova Lenka
- Foroud T.
- Forzan Monica
- Franceschini N.
- Franklin C. S.
- Franklin Christopher S
- Franklin Christopher S
- Frayling T.
- Freathy R. M.
- Fã¶cker M.
- Gaborieau Valerie
- Gaillard R.
- Gallinger Steven
- Gambaro Giovanni
- Garcia M.
- Gasparini P.
- Geller F.
- Geller F.
- Gieger C.
- Giegling Ina
- Gillman M.
- Gillman Mathew
- Goh L. K.
- Gonidakis Fragiskos
- Gorwood Philip
- Grant S. F.
- Grant S. F. A.
- Gratacos Monica
- Gray Emma
- Groen Blokhuis M.
- Gudbjartsson D. F.
- Gudnason V.
- Guo Y.
- Guo Yiran
- Guxens M.
- Hadley D.
- Hakonarson H.
- Hakonarson H.
- Hakonarson Hakon
- Hall P.
- Halmi K. A.
- Hankinson S. E.
- Harris T. B.
- Hattersley A. T.
- Hauser Joanna
- Haworth C. M.
- Hayward C.
- He C.
- Heath A. C.
- Hebebrand J.
- Hebebrand J.
- Hebebrand Johannes
- Heid I. M.
- Heinrich J.
- Helder Sietske
- Hendriks Judith
- Herms Stefan
- Hernandez D. G.
- Herpertz Dahlmann B.
- Herpertz Dahlmann Beate
- Herzog W.
- Herzog Wolfgang
- Hill Adrian
- Hilliard Christopher E
- Hinney A
- Hinney A.
- Hinney Anke
- Hirschhorn J. N.
- Hocher B.
- Hofman A.
- Holloway J. W.
- Holst C.
- Horikoshi M.
- Hottenga J. J.
- Hottenga J. J.
- Hu F. B.
- Huckins Laura M
- Hudson James I
- Huemer Julia
- Huikari V.
- Hunt Sarah E
- Hunter D. J.
- Hypponen E.
- Iezebrink Kirsty
- Illig T.
- Imgart Hartmut
- Ingelsson E.
- Inoko Hidetoshi
- Iã±iguez C.
- Jaddoe V. W.
- Jall S.
- Janout Vladimir
- Jarvelin M. R.
- JimĂ©nez Murcia GeĂÂČrgia EscaramĂ Susana
- Johnson A. D.
- Johnson Craig
- Julia Antonio
- Jã€rvelin M. R.
- Kaakinen M.
- Kalsi Gursharan
- Kaplan A. S.
- Kaplan Allan S
- Kaprio Jaakko
- Karasik D.
- Karhunen Leila
- Karwautz Andreas
- Kas Martien J. H
- Kaye W.
- Kaye Walter
- Keel Pamela
- Kennedy James L
- Keski Rahkonen Anna
- Kesselmeier M.
- Khaw K. T.
- Kiel D. P.
- Kilpelã€inen T. O.
- Kilpelã€inen T. O.
- Kirin M.
- Klareskog Lars
- Klump K. L.
- Klump Kelly L
- Knudsen Gun Peggy S.
- Koeleman Bobby P. C.
- Kolcic I.
- Koller D. L.
- Komaki Gen
- Koubek Doris
- Kowgier M.
- Kraft P.
- Kutalik Z.
- La Via Maria
- Lakka H. M.
- Lakka T. A.
- Lange L. A.
- Langford Cordelia
- Launer L. J.
- Laven J. S.
- Lawlor D. A.
- Le Hellard Stephanie
- Lehtimã€ki T.
- Levitan Robert D
- Levy D.
- Lewin A.
- Lewis Cathryn M
- Li Dong
- Li S.
- Lichtenstein Paul
- Lilenfeld Lisa
- Lin P.
- Lindgren C.
- Lindi V.
- Lissowska Jolanta
- Liu J.
- Logan Darren W
- Loos R. J.
- Lord Graham
- Lundervold Astri
- Lunetta K. L.
- Maggi R.
- Magistretti Pierre
- Magnusson P. K.
- Maj Mario
- Mangino M.
- Marongiu M.
- Marsal Sara
- Marsh J.
- Martaskova Debora
- Martin N. G.
- Mattingsdal Morten
- Maxwell Alexander P
- Mcardle P. F.
- Mcardle W. L.
- Mcardle Wendy L
- Mccarthy M. I.
- Mcginnis Ralph
- Mcguffin Peter
- Melbye M.
- Melbye M.
- Merl Elisabeth
- Metspalu A.
- Metspalu Andres
- Meulenbelt Ingrid
- Middeldorp C.
- Millwood I.
- Mitchell James
- Mohlke K. L.
- Monteleone Palmiero
- Montgomery G. W.
- Mook Kanamori D. O.
- Mooser V.
- Morgan Linda
- Murabito J. M.
- Murray A.
- Murray J. C.
- Murray J. C.
- Murray S. S.
- Mã€nnik Katrin
- MĂŁÂŒller T. D.
- Nalls M. A.
- Navarro P.
- Navratilova Marie
- Nelis M.
- Nengut Suna Gumuscu
- Ness A. R.
- Nivard M.
- Nohr E. A.
- Northstone K.
- Ntalla I.
- Ntalla Ioanna
- O'Reilly P. F.
- Oken E.
- Ong K. K.
- Ong K. K.
- Oostra B. A.
- Ophoff Roel A
- Ouwehand Willem H
- OĂą\u80\u99toole Julie K
- Padyukov Leonid
- Palmer L. J.
- Palmer L. J.
- Palotie A.
- Palotie Aarno
- Panoutsopoulou K.
- Pantel Jacques
- Papezova Hana
- Pararajasingham J.
- Parker A. N.
- Parã© G.
- Peacock M.
- Pearson E. R.
- Pedersen N. L.
- Peltonen L.
- Peltonen Leena
- Peltonen Leena
- Pennell C. E.
- Pennell C. E.
- Perica Vesna Boraska
- Perry J. R.
- Pharoah P.
- Pinto Dalila
- Plotnicov Kathy
- Plump A. S.
- Polasek O.
- Porcu E.
- Potter Simon
- Pourcain B. S.
- Pouta A.
- Power C.
- Price T. S.
- Prokopenko I.
- Rabionet Raquel
- Raevuori Helkamaa Anu
- Rafnar T.
- Raitakari O. T.
- Rajewski Andrzej
- Ramoz Nicolas
- Rayner N. William
- Reichborn Kjennerud Ted
- Reinvang Ivar
- Rice J. P.
- Rich Stephen S
- Ridker P. M.
- Ring S. M.
- Ring Susan M
- Ripatti Samuli
- Ritchie Graham R. S.
- Rivadeneira F.
- Roberts Marion
- Rodriguez A.
- Rotondo Alessandro
- Rudan I.
- Rujescu Dan
- Rybakowski Filip
- Sala C.
- Salem R. M.
- Salomaa V.
- Sambrook Jennifer
- Sandford Richard N
- Sanna S.
- Santonastaso Paolo
- Saw S. M.
- Scherag A.
- Scherag A.
- Scherag AndrĂŁ
- Scherag Susann
- Scherer Stephen W
- Schlessinger D.
- Schmidt Ulrike
- Schork N. J.
- Schork Nicholas J
- Schosser Alexandra
- Schreiber Stefan
- Scuteri A.
- Sebert S.
- Segr㚠A. V.
- Sheerin Neil
- Shuldiner A. R.
- Siitonen N.
- Simell O.
- Simpkin Douglas
- Slachtova Lenka
- Sladek Rob
- Slagboom P. Eline
- Slof OpĂą\u80\u99t Landt Margarita C. T.
- Slopien Agnieszka
- Smith A. V.
- Smith E. N.
- Soranzo N.
- Soranzo Nicole
- Soranzo Nicole
- Southam Lorraine
- Sovio U.
- Sovio U.
- Spector T. D.
- Srinivasan S. R.
- Steen Vidar M
- Stefansson K.
- Stephens Jonathan
- Stolk L.
- Strachan D. P.
- Strachan D. P.
- Strachan David P
- Streeten E. A.
- Strengman Eric
- Strober Michael
- Sulem P.
- Sullivan Patrick F
- Sunyer J.
- Szatkiewicz Jin P
- Szeszenia Dabrowska Neonila
- Sãžrensen T. I.
- Taal H. R.
- Tachmazidou Ioanna
- Taico Chrysecolla
- Tammesoo M. L.
- Tenconi Elena
- Teo Y. Y.
- Thiering E.
- Thornton L. M.
- Thornton Laura M
- Thorsteinsdottir U.
- Tiesler C.
- Tikkanen E.
- Timpson N. J.
- Toniolo D.
- Tortorella Alfonso
- Tozzi Federica
- Trace Sara E
- Treasure Janet
- Treasure Janet
- Tryggvadottir L.
- Tschã¶p M. H.
- Tsitsika Artemis
- Tsui K.
- Tyrer J.
- Tziouvas Konstantinos
- Uda M.
- Uitterlinden A. G.
- Uitterlinden A. G.
- Ulivi S.
- ValcĂŁÂĄrcel B.
- van Beijsterveldt T.
- van Dam R. M.
- van Duijn C. M.
- Van Elburg A.
- van Elburg Annemarie A
- Van Furth Eric F.
- van Meurs J. B.
- van Wingerden S. H.
- Vannberg Frederik O
- Versini Audrey
- Visser J. A.
- Volckmar A. L.
- Vollenweider P.
- Waeber G.
- Wagner Gudrun
- Wareham N. J.
- Warrington M.
- Warrington N. M.
- Waterworth D. M.
- Weedon M. N.
- White S.
- Whittaker Pamela
- Wichmann H. E.
- Wichmann H. Erich
- Widen E.
- Widã©n E.
- Widã©n Elisabeth
- Willemsen G.
- Willemsen G.
- Wilson J. F.
- Wilson J. F.
- Winkler T. W.
- Woodside D. Blake
- Wright A. F.
- Yaghootkar H.
- Yilmaz Zeynep
- Young L.
- Zeggini E.
- Zeggini E.
- Zeggini Eleftheria
- Zeggini Eleftheria
- Zerwas Stephanie
- Zgaga L.
- Zhai G.
- Zhao J. H.
- Zhuang W. V.
- Zipfel S.
- Zipfel Stephan
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2017
- Field of study
The maintenance of normal body weight is disrupted in patients with anorexia nervosa (AN) for prolonged periods of time. Prior to the onset of AN, premorbid body mass index (BMI) spans the entire range from underweight to obese. After recovery, patients have reduced rates of overweight and obesity. As such, loci involved in body weight regulation may also be relevant for AN and vice versa. Our primary analysis comprised a cross-trait analysis of the 1000 single-nucleotide polymorphisms (SNPs) with the lowest P-values in a genome-wide association meta-analysis (GWAMA) of AN (GCAN) for evidence of association in the largest published GWAMA for BMI (GIANT). Subsequently we performed sex-stratified analyses for these 1000 SNPs. Functional ex vivo studies on four genes ensued. Lastly, a look-up of GWAMA-derived BMI-related loci was performed in the AN GWAMA. We detected significant associations (P-values <5 Ă 10-5, Bonferroni-corrected P<0.05) for nine SNP alleles at three independent loci. Interestingly, all AN susceptibility alleles were consistently associated with increased BMI. None of the genes (chr. 10: CTBP2, chr. 19: CCNE1, chr. 2: CARF and NBEAL1; the latter is a region with high linkage disequilibrium) nearest to these SNPs has previously been associated with AN or obesity. Sex-stratified analyses revealed that the strongest BMI signal originated predominantly from females (chr. 10 rs1561589; Poverall: 2.47 Ă 10-06/Pfemales: 3.45 Ă 10-07/Pmales: 0.043). Functional ex vivo studies in mice revealed reduced hypothalamic expression of Ctbp2 and Nbeal1 after fasting. Hypothalamic expression of Ctbp2 was increased in diet-induced obese (DIO) mice as compared with age-matched lean controls. We observed no evidence for associations for the look-up of BMI-related loci in the AN GWAMA. A cross-trait analysis of AN and BMI loci revealed variants at three chromosomal loci with potential joint impact. The chromosome 10 locus is particularly promising given that the association with obesity was primarily driven by females. In addition, the detected altered hypothalamic expression patterns of Ctbp2 and Nbeal1 as a result of fasting and DIO implicate these genes in weight regulation
Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index
- Author
- Adamo P. (Pio) d'
- Adan R. (R.)
- Alavere H. (Helene)
- Albrecht E. (Eva)
- Alexander G. (Graeme)
- Alfredsson L. (Lars)
- Amin N. (Najaf)
- Amin N. (Najaf)
- Anderson C.A. (Carl A)
- Ando T. (Tetsuya)
- Ang W.Q. (Wei)
- Antel J. (J.)
- Aspelund T. (T.)
- Aspelund T. (Thor)
- Atalay M. (Mustafa)
- Baker J.H. (Jessica H)
- Barrett J.C. (Jeffrey)
- Barroso I.E. (InĂȘs)
- Beijsterveldt C.E.M. (Toos) van
- Bencko V. (Vladimir)
- Benke K. (K.)
- Berenson G. (Gerald)
- Bergen A.W. (Andrew)
- Bergen N. (N.)
- Bergmann S.M. (Sven)
- Berrettini W. (Wade)
- Berry D. (Diane)
- Bierut L.J. (L. J.)
- Bierut L.J. (Laura)
- Blackburn H. (Hannah)
- Boerwinkle E. (E.)
- Boerwinkle E.A. (Eric)
- Boni C. (Claudette)
- Boomsma D.I. (Dorret)
- Boraska Perica V. (V.)
- Boyd H.A. (H. A.)
- Bradfield J.P. (Jonathan)
- Brandys M. (M.)
- Breen G. (Gerome)
- Breen G. (Gerome)
- Bruson A. (Alice)
- Bulik C.M. (C. M.)
- Burghardt R. (Roland)
- Buring J.E. (Julie)
- Busonero F.
- Busonero F. (F.)
- Byrne E.M. (E. M.)
- Byrne E.M. (Enda)
- BĂŒhren K. (Katharina)
- Carlberg L. (Laura)
- Chanock S.J. (S. J.)
- Chanock S.J. (Stephen)
- Charoen P. (Pimphen)
- Chasman D.I. (Daniel)
- Cichon S. (Sven)
- Clementi M. (Maurizio)
- Cohen-Woods S. (Sarah)
- Coin L. (Lachlan)
- Collier D.A. (David)
- Cone R.D. (Roger D)
- Conlon P. (Peter)
- Conlon P.J. (Peter J)
- Cooper C. (C.)
- Cooper C. (Charles)
- Cornelis M. (Marilyn)
- Corre T. (Tanguy)
- Couper D.J. (David)
- Cousminer D.L. (Diana)
- Coviello A.D. (Andrea)
- Crawford S. (Steve)
- Crisponi L. (Laura)
- Crow S. (Scott)
- Danner U.N. (Unna N)
- Das S. (Shikta)
- Davey Smith G. (G.)
- Davis O.S.P. (Oliver S.)
- de Geus E.J. (E. J.)
- de Kove C. (Carolien)
- De Zwaan M. (M.)
- Dedoussis G.V. (G. V.)
- Dedoussis G.V. (George)
- Degortes D. (Daniela)
- Deloukas P. (Panagiotis)
- Demerath E.W. (E. W.)
- Demerath E.W. (Ellen)
- DeSocio J.E. (Janiece E)
- Dick D.M. (Danielle)
- Dmitrzak-Weglarz M. (Monika)
- Docampo E. (Elisa)
- Dominiczak A. (Anna)
- Dominiczak A. (Anna)
- Duijn C.M. (Cornelia) van
- Duncanson A. (Audrey)
- Döring A. (Angela)
- Econs M.J. (M. J.)
- Econs M.J. (Michael)
- Edkins T. (Ted)
- Egberts K. (Karin)
- Ehrlich S.M. (Stefan)
- Eiriksdottir G. (Gudny)
- Elburg A.A. (Annemarie) van
- Elks C.E. (Cathy)
- Elliott P. (P.)
- Elliott P. (Paul)
- Esko T. (T.)
- Esko T. (TÔnu)
- Espeseth T. (Thomas)
- Estivill X. (Xavier)
- Evans D.M. (D. M.)
- Faire U. (Ulf) de
- Farmer A.E. (Anne E)
- Favaro A. (Angela)
- Feenstra B. (B.)
- Feenstra B. (Bjarke)
- FernĂĄndez-Aranda F. (Fernando)
- Ferreli L. (Liana)
- Ferrucci L. (L.)
- Fichter M.M. (M. M.)
- Finan C. (Chris)
- Fischer K. (Krista)
- Flexeder C. (Claudia)
- Floyd J. (Jamie)
- Folsom A.R. (A. R.)
- Folsom A.R. (Aaron)
- Foretova L. (Lenka)
- Foroud T. (T.)
- Foroud T. (Tatiana)
- Forzan M. (Monica)
- Franceschini N. (Nora)
- Frayling T.M. (Timothy)
- Freathy R.M. (Rachel)
- Furth E.F. (Eric) van
- Föcker M. (M.)
- Gaborieau V. (Valerie)
- Gaillard R. (R.)
- Gambaro G. (Giovanni)
- Garcia M.E. (M.)
- Gasparini P. (P.)
- Gasparini P. (Paolo)
- Geller F. (Frank)
- Geus E.J.C. (Eco) de
- Gieger C. (Christian)
- Giegling I. (Ina)
- Gillman M.W. (Matthew W.)
- Goh L.K. (L. K.)
- Gonidakis F. (Fragiskos)
- Gorwood P. (Philip)
- Grant S.F.A. (S. F.A.)
- Grant S.F.A. (Struan)
- Gratacos M. (Monica)
- Gray E. (Emma)
- Groen-Blokhuis M. (Maria)
- Gudbjartsson D.F. (Daniel)
- Gudnason V. (V.)
- Guo Y. (Yongli)
- Guxens Junyent M. (MĂČnica)
- Hadley D. (D.)
- Hagen K. (Knut)
- Hakonarson H. (Hakon)
- Halmi K.A. (K. A.)
- Hankinson S.E. (S. E.)
- Harris T.B. (Tamara)
- Hattersley A.T. (Andrew)
- Hauser J. (J.)
- Haworth C.M.A. (Claire M.)
- Hayward C. (Caroline)
- He C. (C.)
- Hebebrand J. (J.)
- Heid I.M. (Iris)
- Heinrich J. (J.)
- Helder S. (Sietske)
- Hendriks J. (Judith)
- Herms S. (Stefan)
- Hernandez D.G. (Dena)
- Herpertz-Dahlmann B. (B.)
- Herzog W. (W.)
- Hilliard C.E. (Christopher E)
- Hinney A. (Anke)
- Hirschhorn J.N. (Joel)
- Hocher B. (Berthold)
- Hofman A. (Albert)
- Holloway J.W. (J. W.)
- Holst J.J.
- Horikoshi M. (Momoko)
- Hottenga J.J. (Jouke Jan)
- Hu F.B. (F. B.)
- Huckins L.M. (Laura M)
- Hudson J.I. (James I)
- Huemer J. (Julia)
- Huikari V. (Ville)
- Hunt S.E. (Sarah E)
- Hypponen E. (E.)
- Hypponen E. (Elina)
- Iezebrink K. (Kirsty)
- Illig T. (T.)
- Imgart H. (Hartmut)
- Ingelsson E. (Erik)
- Inoko H. (Hidetoshi)
- Iñiguez C. (C.)
- Jaddoe V.W. (V. W.)
- Jaddoe V.W.V. (Vincent)
- Jall S. (S.)
- Janout V. (Vladimir)
- Jarvelin M.-R. (Marjo-Riitta)
- Jarvelin M.R. (M. R.)
- JimĂ©nez-Murcia G.E.S. (GeĂČrgia EscaramĂ Susana)
- Johnson A.D. (Andrew)
- Julia A. (Antonio)
- Kaakinen M. (M.)
- Kalsi G. (Gursharan)
- Kaplan A.S. (Allan S)
- Kaprio J. (Jaakko)
- Kaprio J. (Jaakko)
- Karasik D. (David)
- Karhunen L. (Leila)
- Karwautz A. (Andreas)
- Kas M.J.H. (Martien)
- Keel P. (Pamela)
- Kennedy J.L.
- Keski-Rahkonen A. (Anna)
- Kesselmeier M. (M.)
- Khaw K.T. (K. T.)
- Kiel D.P. (Douglas P.)
- KilpelÀinen T.O. (Tuomas)
- Klump K.L. (K. L.)
- Knudsen G.P.S. (Gun Peggy S.)
- Koeleman B.P.C. (Bobby P. C.)
- Koeleman B.P.C. (Bobby)
- Kolcic I. (Ivana)
- Koller D.L. (Daniel)
- Komaki G. (Gen)
- Koubek D. (Doris)
- Kowgier M. (Matthew)
- Kraft P. (Peter)
- Kutalik Z. (ZoltĂĄn)
- La Via M. (Maria)
- Lakka T.A. (Timo)
- Lange L.A. (Leslie)
- Langford C. (Cordelia)
- Launer L.J. (Lenore)
- Laven J.S. (J. S.)
- Lawlor D.A. (D. A.)
- Lawlor D.A. (Debbie)
- Le Hellard S. (Stephanie)
- LehtimÀki T. (Terho)
- Levitan R.D. (Robert D)
- Levy D. (D.)
- Lewin A. (Alex)
- Lewis C.M. (Cathryn)
- Li D. (Dong)
- Li S. (S.)
- Lichtenstein P. (Paul)
- Lilenfeld L. (Lisa)
- Lin P. (P.)
- Lindi V. (Virpi)
- Lissowska J. (Jolanta)
- Liu J. (J.)
- Logan D.W. (Darren W)
- Loos R.J.F. (Ruth)
- Lord G. (Graham)
- Lundervold A.J. (Astri)
- Lunetta K.L. (Kathryn)
- Maggi R. (Reedik)
- Magistretti P. (Pierre)
- Magnusson P.K. (Patrik)
- Maj M. (Mario)
- Mangino M. (Massimo)
- Marsal S. (Sara)
- Marsal S. (Sara)
- Martaskova D. (Debora)
- Martin N.G. (N. G.)
- Mattingsdal M. (Morten)
- Mattingsdal M. (Morten)
- Maxwell A.P. (A.)
- McArdle P.F. (P. F.)
- McCarthy M.I. (M. I.)
- McGinnis R. (Ralph)
- Mcguffin P. (Peter)
- Melbye M. (Mads)
- Merl E. (Elisabeth)
- Metspalu A. (Andres)
- Meulenbelt I. (Ingrid)
- Meurs J.B.J. (Joyce) van
- Middeldorp C.M. (Christel)
- Millwood I.Y. (Iona)
- Mitchell J. (James)
- Mohlke K.L. (Karen)
- Monteleone P. (Palmiero)
- Montgomery G.W. (G. W.)
- Mook-Kanamori D.O. (D. O.)
- Murabito J. (Joanne)
- Murray J.C. (Jeffrey)
- MĂ€nnik K. (Katrin)
- MĂŒller T.D.
- Nalls M.A. (Michael)
- Navarro P. (Pau)
- Navratilova M. (Marie)
- Nelis M. (M.)
- Nengut S.-G. (Suna-Gumuscu)
- Ness A.R. (A. R.)
- Ness A.R. (Andrew)
- Nivard M. (Michel)
- Nohr C. (Christian)
- Ntalla I. (Ioanna)
- O'Reilly P.F. (P. F.)
- Oken E. (Emily)
- Ong K.K. (K. K.)
- Oostra B.A. (Ben)
- Ophoff R.A. (Roel)
- Ouwehand W.H. (Willem)
- OâToole J.K. (Julie K)
- Padyukov L. (L.)
- Padyukov L. (Leonid)
- Palmer C. (Cameron)
- Palotie A. (A.)
- Palotie A. (Aarno)
- Panoutsopoulou K. (K.)
- Pantel J. (Jacques)
- Papezova H. (Hana)
- Pararajasingham J. (Jennifer)
- Pare G. (Guillame)
- Parker A.N. (Alex)
- Peacock M. (M.)
- Peacock M. (Munro)
- Pearson E.R. (E. R.)
- Pedersen N.L. (Nancy)
- Peltonen L. (Leena Johanna)
- Pennell C.E. (Craig)
- Perry J.R. (J. R.)
- Pinto D. (Dalila)
- Pinto D. (Duane)
- Plump A.S. (A. S.)
- Polasek O. (Ozren)
- Porcu E. (Eleonora)
- Potter S.C. (Simon)
- Power C. (Christopher)
- Price T.S. (Thomas)
- Prokopenko I. (Inga)
- Rabionet R. (Raquel)
- Raevuori-Helkamaa A. (Anu)
- Rafnar T. (Thorunn)
- Raitakari O.T. (O. T.)
- Rajewski A. (Andrzej)
- Ramoz N. (Nicolas)
- Rayner N.W. (Nigel William)
- Reinvang I. (Ivar)
- Rice J.P. (John)
- Rich S.S. (Stephen)
- Ridker P.M. (Paul)
- Ring S.M. (Susan)
- Ripatti S. (Samuli)
- Ritchie G.R.S. (Graham R.S.)
- Rivadeneira Ramirez F. (Fernando)
- Rivadeneira F. (F.)
- Roberts M. (Marion)
- Rodriguez A. (A.)
- Rotondo A. (Alessandro)
- Rujescu D. (Dan)
- Rybakowski F. (Filip)
- Sala C. (Cinzia)
- Salem R.M. (Rany)
- Salomaa V. (Veikko)
- Sambrook J. (Jennifer)
- Sandford R. (Richard)
- Sanna S. (Serena)
- Santonastaso P. (Paolo)
- Saw S.M. (S. M.)
- Scherag A. (A.)
- Scherag A. (Andre)
- Scherer S.W. (Stephen W)
- Scherer S.W. (Stephen)
- Schlessinger D. (D.)
- Schmidt U. (Ulrike)
- Schosser A. (Alexandra)
- Schreiber S. (Stefan)
- Scuteri A. (A.)
- Scuteri A. (Angelo)
- Sebert S. (S.)
- SegrĂš A.V. (Ayellet)
- Sheerin N. (Neil)
- Siitonen N. (Niina)
- Simpkin D. (Douglas)
- Slachtova L. (Lenka)
- Sladek R. (Rob)
- Slagboom P.E. (Eline)
- Slof-Opât Landt M.C.T. (Margarita C. T.)
- Slopien A. (Agnieszka)
- Smith A.V. (Albert)
- Smith A.V. (Davey)
- Smith A.V. (Davey)
- Soranzo N. (Nicole)
- Soranzo N. (Nicole)
- Southam L. (Lorraine)
- Sovio U. (Ulla)
- Spector T.D. (Timothy)
- Srinivasan S.R. (Sathanur)
- Steen V.M. (Vidar)
- Stephens J. (Jonathan)
- Stolk L. (Lisette)
- Strachan D.P. (David)
- Streeten E.A. (Elizabeth)
- Strengman E. (Eric)
- Strober M. (Michael)
- Sulem P. (Patrick)
- Sullivan P.F. (Patrick)
- Sunyer J. (J.)
- Sunyer J. (Jordi)
- Szatkiewicz J.P. (Jin P)
- Szeszenia-Dabrowska N. (Neonila)
- SĂžrensen T.I.A. (Thorkild)
- Taal H.R. (Rob)
- Tachmazidou I. (Ioanna)
- Taico C. (Chrysecolla)
- Tammesoo M.L. (M. L.)
- Tenconi E. (Elena)
- Teo Y.Y. (Y. Y.)
- Teo Y.Y. (Yik Ying)
- Thiering E. (Elisabeth)
- Thornton L.M. (Laura)
- Thorsteinsdottir U. (Unnur)
- Tiesler C. (C.)
- Tikkanen E. (Emmi)
- Timpson N.J. (Nicholas)
- Toniolo D. (Daniela)
- Tortorella A. (Alfonso)
- Tozzi F. (Federica)
- Trace S.E. (Sara E)
- Treasure J. (Janet)
- Tryggvadottir L. (Laufey)
- Tschop M. (Matthias)
- Tschöp M.H. (M. H.)
- Tsitsika A. (Artemis)
- Tsitsika A. (Artemis)
- Tyrer J. (J.)
- Tziouvas K. (Konstantinos)
- Uda M. (M.)
- Uitterlinden A.G. (André)
- Ulivi S. (Shelia)
- ValcĂĄrcel B. (Beatriz)
- van Dam R.M. (R. M.)
- Vannberg F.O. (Frederik O)
- Versini A. (Audrey)
- Visser J.A. (Jenny)
- Volckmar A.-L. (A. L.)
- Vollenweider P. (Peter)
- Waeber G. (GĂ©rard)
- Wagner G. (Gudrun)
- Wareham N.J. (Nick)
- Warrington M. (M.)
- Warrington N.M. (Nicole)
- Waterworth D. (Dawn)
- Weedon M.N. (Michael)
- White S.J. (Stefan)
- Whittaker P. (Pamela)
- Wichmann H.E. (Heinz Erich)
- Widen E.
- Widen E. (E.)
- Willemsen G.A.H.M. (Gonneke)
- Wilson J.F. (J. F.)
- Wingerden S. (Sophie) van
- Winkler T.W. (Thomas W.)
- Woodside D.B. (D Blake)
- Wright A.F. (Alan)
- Yaghootkar H. (H.)
- Yilmaz Z. (Zeynep)
- Young L. (L.)
- Zeggini E. (Eleftheria)
- Zerwas S. (Stephanie)
- Zgaga L. (L.)
- Zhai G. (G.)
- Zhao J.H. (J. H.)
- Zhuang W.V. (W. V.)
- Zipfel S. (S.)
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/02/2017
- Field of study
The maintenance of normal body weight is disrupted in patients with anorexia nervosa (AN) for prolonged periods of time. Prior to the onset of AN, premorbid body mass index (BMI) spans the entire range from underweight to obese. After recovery, patients have reduced rates of overweight and obesity. As such, loci involved in body weight regulation may also be relevant for AN and vice versa. Our primary analysis comprised a cross-trait analysis of the 1000 single-nucleotide polymorphisms (SNPs) with the lowest P-values in a genome-wide association meta-analysis (GWAMA) of AN (GCAN) for evidence of association in the largest published GWAMA for BMI (GIANT). Subsequently we performed sex-stratified analyses for these 1000 SNPs. Functional ex vivo studies on four genes ensued. Lastly, a look-up of GWAMA-derived BMI-related loci was performed in the AN GWAMA. We detected significant associations (P-values <5 Ă 10-5, Bonferroni-corrected P<0.05) for nine SNP alleles at three independent loci. Interestingly, all AN susceptibility alleles were consistently associated with increased BMI. None of the genes (chr. 10: CTBP2, chr. 19: CCNE1, chr. 2: CARF and NBEAL1; the latter is a region with high linkage disequilibrium) nearest to these SNPs has previously been associated with AN or obesity. Sex-stratified analyses revealed that the strongest BMI signal originated predominantly from females (chr. 10 rs1561589; Poverall: 2.47 Ă 10-06/Pfemales: 3.45 Ă 10-07/Pmales: 0.043). Functional ex vivo studies in mice revealed reduced hypothalamic expression of Ctbp2 and Nbeal1 after fasting. Hypothalamic expression of Ctbp2 was increased in diet-induced obese (DIO) mice as compared with age-matched lean controls. We observed no evidence for associations for the look-up of BMI-related loci in the AN GWAMA. A cross-trait analysis of AN and BMI loci revealed variants at three chromosomal loci with potential joint impact. The chromosome 10 locus is particularly promising given that the association with obesity was primarily driven by females. In addition, the detected altered hypothalamic expression patterns of Ctbp2 and Nbeal1 as a result of fasting and DIO implicate these genes in weight regulation
Utilisation of an operative difficulty grading scale for laparoscopic cholecystectomy (vol 33, pg 110, 2019)
- Author
- Aawsaj Yousif
- Abayomi Michael
- Acharya Vikas
- Aggarwal Smeer Kumar
- Ahmad Anwar
- Ahmed Irfan
- Ahmed Jamil
- Ahmed Javed
- Ahmed Talat
- Ainley Paul
- Akhtar Mansoor
- Al-Abed Yahya A.
- Al-Akash Musallam
- Al-Bahrani Ahmed Z.
- Al-Khyatt Waleed
- Al-Muhktar Ahmed
- Al-Sarireh Bilal
- Al-Taan Omer
- Alagaratnam Swethan
- Alam Imran
- Alberts Justin
- Alderson Derek
- Aldridge Roland C.
- Aleksandrov Danail
- Ali Haythem
- Ali Shahda
- Amari Khalid Al
- Amin Khalid
- Andrew David R.
- Angharad Jones M.
- Appleton Shaun
- Arhi Chanpreet
- Aroori Somaiah
- Aryal Kamal
- Asad Mehek
- Aseem Rabiya
- Asprou Fotini M.
- Awan Altaf
- Ayaani Soofiyah
- Aymon Null
- Babu Benoy I.
- Bajwa Dalvir S.
- Bajwa Farrukh M.
- Baker Andrew L.
- Balfe Paul
- Ball William R.
- Ballance Laura
- Banwell Victoria
- Barnes James
- Barrie Jenifer
- Bartlett Francis
- Basheer Mohammed
- Bashir Gareth
- Basra Melvinder
- Basu Sanjoy
- Basynat Pradeep
- Batt Jeremy
- Bausbacher Harald
- Bawa Sadiq
- Beasley William D.
- Belding Rowena
- Bellini Maria Irene
- Bennett Stephen P.
- Bhandari Christopher Taylor Santosh
- Bhattacharya Vish
- Blane Christine
- Blazeby Jane M.
- Boal Matthew
- Boddy Alexander
- Boland Michael
- Bond-Smith Giles
- Booth Michael I.
- Borowski David W.
- Bowen Laura
- Boyce Kathryn M.
- Boyd Alan T.
- Bradley Donal
- Bradley Neil
- Brennan Stephen
- Brett Daniel
- Broadhurst Jack
- Brooke Eleanor
- Brown Timothy H.
- Bryant Alice
- Buchan Joanna
- Bullen Naomi
- Bunnell Catherine
- Bunting David M.
- Burke Paul
- Byrne James P.
- Byrnes Colman K.
- Campbell William
- Carney Kate
- Carney Kate
- Carroll Paul
- Carter Nicholas C.
- Carty Nick
- Cassidy John T.
- Chambers Adam
- Chambers Alice
- Chambers Alice
- Chan Wei Ming
- Chang Jessica
- Charalabopoulos Alexandros
- Chauhan Neal
- Cheung Melanie
- Chishti Imran A.
- Chitre Vivek
- Choy Alfred
- Cieplucha Krzysztos
- Clements Joshua M.
- Coats Maria
- Cockbain Andrew J.
- Coe Peter O.
- Connelly Martin
- Cooke Fiachra
- Courtney Michael J.
- Cowley Jonathan B.
- Cross Keith S.
- Cuming Tamzin
- Cunha Pedro
- D\u2019Costa Conrad
- Dalgaty Faith
- Dar Farooq
- Date Ravindra
- Dave Rajiv V.
- Davey Phil
- Davies James
- Dawson Suzanne
- De Marchi Joshua A.
- de Siqueira Jonathan
- Deguara Jean
- Delisle Theo G.
- Dennison A. R.
- Derbyshire Laura
- Devoto Laurence
- Dhillon Ajit
- Diamond Tom
- Dickson-Lowe Richard
- Digney Ruairi
- Dindyal Shiva
- Dobbins Brian
- Doe Matthew
- Dorrian Emmet
- Doulias Triantafyllos
- Downing Justine
- Drake Benjamin
- Driscoll Peter J.
- Duke Diana
- Durkin Damien
- Dwerryhouse Simon J.
- Ebdewi Hamdi
- Ebied Husam
- Eisawi Abdalla
- El-Dhuwaib Arslan Pannu Yesar
- El-Hasani Shamsi S.
- Elkheir Natalie
- Elmasry Mohamed
- Elsayed Mohammed
- Elshaer Mohamed
- Emesih Sophie
- Farag Sameh F.
- Farooq Ansar
- Farouk Marwan
- Fasih Tani
- Fawole Adeshina S.
- Fenwick Stephen
- Ferguson Graeme
- Ferris Paul
- Finch David
- Finch J. G.
- Finlay Ian
- Fleming Katie
- Fletcher Ted
- Fordham Imogen J.
- Forouzanfar Amir
- Forrest Craig R.
- Forster Luke
- Fothergill Laura
- Frame Richard J.
- Francombe James
- Frank Lucinda
- Fusai Guiseppe
- Galanopoulos Giorgios
- Gallagher Paul V.
- Garcea Giuseppe
- Gardner-Thorpe James
- Geoghegan Justin G.
- Geogloma Ileana
- Gerakopoulos Stratos
- Ghareeb Essam
- Ghazanfar Mudassar A.
- Gibson Simon
- Giles Mathew
- Giovinazzo Francesco
- Goh Yan Li
- Gopalswamy Sivakumar
- Goscimski Andrzej
- Gossage James A.
- Gough Martin
- Gould Laura
- Gould Laura
- Grant Alan J.
- Gravante Gianpiero
- Griffiths Ewen A.
- Griffiths Ewen A.
- Gull Sadaf
- Gunasekera Rohan T.
- Gurung Kabita
- Guthrie Graeme J. K.
- Guy Finch J.
- Hafiz Shazia
- Halkias Constantine
- Hall Claire
- Hamady Zayed
- Hamdan Alhafidz
- Hamdan Mohammed F.
- Hamilton Emma
- Hancorn Kate
- Haque Manzarul
- Haque Samer Ul
- Hardy Thomas J.
- Hargreaves Anita
- Harilingam Alok Chhabra Mohan
- Harris Andrew
- Harrison Ewen
- Hawkins Helen
- Heath Jonathan
- Hebbar Madhusoodhana
- Henderson Lucy T.
- Henley Natasha
- Heshaishi Mohamed
- Hewes James
- Hewes James C.
- Heywood Nick
- Higgs Simon M.
- Hill Arnold D. K.
- Hill Arnold D. K.
- Hindley Caroline
- Hirst Natalie A.
- Hisham Elzanati
- Ho Wei-Min
- Hoban Jennifer R.
- Hodgkins Kathryn A.
- Hodson James
- Holroyd David J.
- Hooks Gareth
- Hopwood Benjamin
- Hornby Reena Shah Steve T.
- Hornsby Jane
- Hosie Kenneth B.
- Hosie Kenneth B.
- Hossack Martin R.
- Hossain Tanvir
- Hoti Emir
- Hou David
- Hrycaiczuk Alex
- Hughes Michael
- Hunter David I.
- Hussain Abdulzahra A.
- Hussain Adnan
- Hussain Anwar
- Hussain Najam
- Iftikhar Syed Yusuf
- Iqbal Lola Giwa Nusrat
- Iskandar Edrin
- Issa Eyad
- Ivanovski Ivan
- Jackson Andrew
- Jackson Claire
- Jafferbhoy Sadaf F.
- Jambulingam Periyathambi
- Jamdar Saurabh
- Jamel Sara
- Janeczko Adam
- Jaunoo Shameen
- Jayanthi Naga V. G.
- Jelley Clare
- Jennings Neil A.
- Joel Abraham
- John Terrace Stephen O\u2019Neill.
- Johnpulle Michelle A.
- Johnston Dorothy
- Johnstone Marianne
- Johnstone Marianne
- Joji Nikita
- Jones Claire
- Jones Elinor
- Jones Gareth H.
- Jones Michael J.
- Jones Robert P.
- Jones Steven M.
- Kadhim Abbas
- Kadirkamanathan Sritharan
- Kallaway Charlotte
- Kanakala Venkatesh
- Kanavati Osama
- Kansal Nisheeth
- Kaptanis Sarantos
- Karavadra Babu
- Karim Lawen
- Karunakaran Priyadarssini
- Katbeh Tarek
- Kaur Parminder
- Kausar Ambareen
- Kelly Michael E.
- Kendal Chris
- Kennedy David
- Kenny Ross
- Keogh Ken
- Khalil Ahmed M.
- Khan Amarah
- Khan Mohammad A.
- Khan Muhammad A. S.
- Khan Raja Basit
- Khan Shabuddin
- Khan Shahab
- Khawaja Amir
- Khawaja Zechan
- Khogali Elmoataz
- Kimble Adam
- Kinghorn Alison
- Kirkham Amanda J.
- Knight Benjamin
- Knight Katrina
- Kourkulos Michail
- Krysztopik Richard
- Kumar Pradeep
- Kynaston James
- Kyriakidis Dimitrios
- Lalla Kushik
- Lambert Joel
- Lane Risha
- Larkin David
- Law Jennifer
- Lawther Roger
- Lazim Taha
- Lee Kathryn
- Lee Matthew
- Leeder Paul
- Lennon Hannah
- Lewis Michael
- Lim Henry C. C.
- Lim Pei J.
- Lindsay David
- Lloyd David
- Lo Christina
- Lodhia Joshil
- Longbotham David A.
- Loughlin Paula
- Lovett Bryony
- Luhmann Andreas
- Luther Ali Alison
- Lyons Emma M.
- Macano Christina A. W.
- Macartney Matthew
- Macdonald Andrew
- Madanipour Suroosh
- Madbak Khaliel
- Madurska Marta
- Magee Conor J.
- Maguire Donal
- Maharaj Geta
- Majeed Ali
- Malcolm Cathy
- Malde Deep
- Malik Nabeela S.
- Mallik Mekhlola
- Mansour Sami
- Manu Mangta
- Manzelli Antonio
- Marriott Paul
- Marriott Paul
- Martin Jack
- Martin Sean T.
- Martin Serena
- Marudanayagam Ravi
- Mason Denise
- Mathur Pawan
- Mawhinney Abi
- Mbuvi James
- Mcaree Barry
- Mccain Stephen
- Mccallum Iain J. D.
- Mcclarey Andrew
- Mccune Ken
- Mcdermott Frank
- Mcentee Gerry P.
- Mcglone Emma R.
- Mcguigan Andrew
- Mcilmunn Colin
- Mckay Damian
- Mckenzie Stephen
- Mcnair Angus G. K.
- Mealy Ken
- Menzies Donald
- Mercer Stuart J.
- Milburn James
- Mirza Ahmed K.
- Mirza Darius
- Miu Victor
- Mockford Justine Downing Katherine A.
- Mohamed Simon Lammy Sarah
- Mohan Helen M.
- Mok Kam Wa Jessica
- Monk David
- Morcous Paul
- Morrison Tamsin E. M.
- Mothe Bhavani Sidhartha
- Mowbray Nicholas
- Mozolowski Kirsty L.
- Mukherjee Dipankar
- Murphy James O.
- Murtaza Ghulam
- Nally Deirdre M.
- Napetti Sara
- Nassar Ahmad H.
- Nassar Ahmad H. M.
- Naumann David
- Nedujchelyn Yuwaraja
- Needham Paul J.
- Newton Katy
- Newton Richard C.
- Ngu Wee Sing
- Nicholson Gary A.
- Nicholson James
- Nicholson James A.
- Nicol Laura
- Nicolay Christopher R.
- Nieto Tom
- Nijjar Rajwinder S.
- Nilsen-Nunn April
- Nilsson Frida
- Noble Fergus
- Nofal Emma
- Noor Nigel
- Nunes Quentin M.
- O\u2019Dwyer Patrick
- O\u2019Neill Maeve A.
- O\u2019Reilly Derek A.
- O\u2019Shea Kathryn M.
- O\u2019Sullivan Adrian W.
- Obeidallah Moh\u2019d Rami
- Ogedegbe Arikoge
- Old Oliver J.
- Orchard Philippa
- Orizu Mavis N.
- Packer Jessica R.
- Padwick Robert
- Panteleimonitis Sofoklis
- Parappally Ciny P.
- Parmar J.
- Pasquali Sandro
- Patel Abhilasha
- Patel Krashna
- Patel Shakira
- Pati Pradeep
- Pearce Belinda
- Pearson Katherine L.
- Peirce Colin
- Pellen Mike
- Peter Mark B.
- Peterson Mark
- Pezzuto Roberto
- Photi Evangelos
- Phull Manraj
- Pinho-Gomes Ana C.
- Pollock Sarah
- Popplewell Matthew
- Pore Naresh
- Porter Jonathan
- Prasad Abheesh R.
- Prasad Raj
- Preston Shaun R.
- Preziosi Giuseppe
- Prince Sarah
- Psica Alicja
- Puig Sonia
- Puntis Daniel J.
- Puri Yogesh
- Qandeel Haitham
- Rabie Mohamed
- Radwan Rami
- Rae David M.
- Rahman Saquib
- Rajaganeshan Rajasundaram
- Rajendran Ilayaraja
- Ramage Michael I.
- Rao Sudhindra T. V.
- Rate Anthony J.
- Raza Soulat
- Read Edward
- Reddy Marcus
- Reece-Bolton Obuobi
- Reed Joanna
- Reid Alistair
- Rengifo Carla
- Rhys Thomas
- Richards Colin H.
- Riera Manel
- Ritchie Judith
- Robb William
- Roberts Geoffrey P.
- Robinson Sarah
- Robinson Steven J.
- Robinson Stuart
- Rodriguez Dan
- Rodriguez Daniel Urriza
- Roebuck Amanda
- Rogers Paul N.
- Rolph Rachel C.
- Ross Carter C.
- Roy Sudipta
- Rutherford Claire L.
- Sadat Mohammed M.
- Sakai Naomi
- Sampat Keerthika
- Samuel Nehemiah
- Sarmah Piyush B.
- Sarvananthan Kas
- Sarveswaran Janahan
- Satheesan Steve
- Saunders Michael
- Sayegh Mazin
- Segaran Ashvina
- Sekhar Hema
- Sen Gourab
- Seymour Keith
- Shabo Wael
- Shah Nayab
- Shahin Yousef
- Sheel Andrea R. G.
- Shenoy Hrishikesh
- Shetty Vinutha
- Shier David
- Shingler Guy M.
- Shiwani Muhammad Hanif
- Shrestha Ashish Kiran
- Siddiqi Najaf
- Siddiqui Midhat N.
- Siddiqui Zohaib
- Sillo Toritseju O.
- Silva Michael
- Simpson Duncan J.
- Singh Shailendra
- Singh-Ranger Deepak
- Sinha Sidhartha
- Skelly Brendan L.
- Slavin John P.
- Slawinski Corinna
- Sloane Jake
- Smith Stella R.
- Smith Stella R.
- Spearman John
- Spence Gary
- Spreadborough Philip
- Spreadborough Philip
- Starmer Benjamin Z.
- Stevenson Thomas E. J.
- Stewart Duncan J.
- Stirland E.
- Subramanium Dhivya
- Sufi Pratik A.
- Sukha Anisha
- Sutcliffe Robert
- Suttie Stuart
- Sutton Cherith M. L. R.
- Szentpali Karoly
- Tang Cheuk-Bong
- Tanner Nicola
- Tate Sophie
- Tayeh Salim
- Taylor Greg W.
- Teasdale Rebecca L.
- Templeton Alexa
- Thakkar Rohan
- Thomas George
- Thompson Ronald L. E.
- Tilston Michael P.
- Toh Simon K. C.
- Tolofari Sotonye
- Tomlinson Mark A.
- Trevatt Alexander E. J.
- Trotter Martin
- Tsang Andrew
- Tsavellas George
- Tuck Liz
- Turner Paul
- Tutton Matthew G.
- Ullah Muhammad Fahad
- Upchurch Emma A.
- Urbonas Tomas
- Varghase Joseph
- Vass David G.
- Vaughan Elizabeth M.
- Vijay Vardhini
- Vijayan Deepak
- Vijayanand Dhakshinamoorthy
- Villatoro Eduardo
- Virupaksha Suvi
- Vitone Louis J.
- Vohra Ravi S.
- Vohra Ravinder S.
- Wadley Martin
- Wainwright Denise
- Wajed Saj
- Wallace Tom
- Wardle Stacy
- Warren Conor
- Watkin Helen
- Watson Angus J. M.
- Watson Nicholas F.
- Wayman John
- Weaver Simon
- Weber Beatrix
- Weber Beatrix
- Weerasinghe Chamindri
- Welbourn Hannah
- Wheatley Kevin
- White Timothy J.
- Wijetunga Imeshi
- Wild Jonathan R. L.
- Wilkinson Marc D.
- Williams Sophie V.
- Williamson Tracey K.
- Willson Peter D.
- Wilson Michael S. J.
- Wilson Timothy R.
- Winter Des C.
- Winter Hannah
- Wood Christopher P. J.
- Wood Peter
- Wood Simon
- Woodman Thomas
- Yahya Salama
- Yao Caroline
- Yeldham Geoffrey
- Yoganathan Thusidaran
- Youssef Haney
- Zafar Sara
- Zafrani Zakhi
- Zarsadias Prizzi
- Zeeshan Saquib
- Zhang Catherine
- Zino Samer
- Ziprin Paul
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
Genomic reconstruction of the SARS-CoV-2 epidemic in England
- Author
- Aanensen David M
- Abnizova Irina
- Abudahab Khalil
- Adams Alexander
- Adams Helen
- Afifi Safiah
- Aggarwal Dinesh
- Ahmad Shazaad SY
- Aigrain Louise
- Alcolea Adela
- Alderton Alex
- Ali Mozam
- Alikhan Nabil-Fareed
- Allara Elias
- Allen Laura
- Amato Roberto
- Anderson Ralph
- Angyal Adrienn
- Annett Tara
- Aplin Stephen
- Ariani Cristina
- Ariani Cristina V
- Asad Hibo
- Ash Amy
- Ashfield Paula
- Ashford Fiona
- Atkinson Laura
- Attwood Stephen W
- Auckland Cressida
- Austin-Guest Siobhan
- Aydin Alp
- Baker David J
- Baker Paul
- Bala Sendu
- Balcazar Carlos E
- Ball Jonathan
- Barrett Jeffrey
- Barrett Jeffrey C
- Barrow Magdalena
- Barton Edward
- Bashton Matthew
- Bassett Andrew
- Bassett Andrew R
- Batra Rahul
- Battleday Kristina
- Baxter Chris
- Bayzid Nadua
- Beal James
- Beale Mathew
- Beaver Charlotte
- Beckett Angela H
- Beckwith Shaun M
- Bedford Luke
- Beer Robert
- Beggs Andrew
- Bellany Sam
- Bellerby Tristram
- Bellis Katherine L
- Bellis Katie
- Berger Duncan
- Berriman Matt
- Berry Louise
- Bertolusso Beatrice
- Best Angus
- Betteridge Emma
- Bevan Paul
- Bibby David
- Bicknell Kelly
- Binley Simon
- Binns Debbie
- Birchley Alec
- Bird Paul W
- Birney Ewan
- Bishop Chloe
- Bishop Jason
- Blackburn Kirsty
- Blacow Rachel
- Blakey Victoria
- Blane Beth
- Bolt Frances
- Bonfield James
- Bonner Stephen
- Bonsall David
- Boswell Tim
- Bosworth Andrew
- Boughton Nick
- Bourgeois Yann
- Bowker Sam
- Boyd Olivia
- Bradley Declan T
- Breen Cassie
- Brendler-Spaeth Timothy
- Bresner Catherine
- Breuer Judith
- Bridgett Stephen
- Bronner Iraad
- Bronner Iraad F
- Brooklyn Tanya
- Brooks Ellena
- Broos Alice
- Brown Julianne R
- Bucca Giselda
- Buchan Sarah L
- Buck David
- Buddenborg Sarah Kay
- Bull Matthew
- Burns Phillipa J
- Burton-Fanning Shirelle
- Bush Robert
- Byaruhanga Timothy
- Byott Matthew
- Caetano Catarina
- Cagan Alex
- Campbell Sharon
- Carabelli Alessandro M
- Cargill James S
- Carlile Matthew
- Carter Nicola
- Cartwright Joanna
- Carvalho SĂlvia F
- Casey Anna
- Castigador Anibolina
- Catalan Jana
- Chalker Vicki
- Chaloner Nicola J
- Chand Meera
- Chand Meera
- Chapman Liz
- Chappell Joseph G
- Charalampous Themoula
- Chatterton Wendy
- Chaudhry Yasmin
- Chillingworth Tracey-Jane
- Churcher Carol M
- Clapham Peter
- Clark Gemma
- Clark Richard
- Clarke Adrian
- Clarke Catriona
- Clarke Phillip
- Cogger Benjamin J
- Cole Daryl
- Cole Kevin
- Collins Jennifer
- Colquhoun Rachel
- Connor Thomas R
- Cook Elizabeth
- Cook Kate F
- Coombes Jason
- Coppola Maria
- Corden Sally
- Cormie Claire
- Cornell Linda
- Cornwell Clare
- Cortes Nicholas
- Corton Craig
- Cotic Marius
- Cotton Seb
- Cottrell Simon
- Coupland Lindsay
- Cox Alison
- Cox MacGregor
- Crackett Abby
- Craine Noel
- Cranage Alison
- Craven Harriet
- Craw Sarah
- Crawford Liam
- Crawford Mark
- Cross Aidan
- Crown Matthew R
- Crudgington Dorian
- Cumley Nicola
- Curran Martin D
- Curran Tanya
- Cutts Tim
- da Silva Filipe Ana
- Dabrera Gavin
- Dabrowska Monika
- Darby Alistair C
- Davidson Rose K
- Davies Alisha
- Davies Matt
- Davies Robert
- Davies Robert M
- Davis Thomas
- Dawson Joseph
- Day Callum
- de Angelis Daniela
- De Lacy Elen
- De Maio Nicola
- de Oliveira Martins Leonardo
- de Silva Thushan I
- Debebe Johnny
- Densem Aiden
- Denton-Smith Rebecca
- Dervisevic Samir
- Dewar Rebecca
- Dey Jayasree
- Dias Joana
- Dibling Thomas
- Dobie Donald
- Dockree Cat
- Dodd David
- Dogga Sunil
- Dorman Matthew
- Dorman Matthew J
- Dougan Gordon
- Dougherty Martin
- Dove Alexander
- Downing Fatima
- Drummond Lucy
- Drury Eleanor
- du Plessis Louis
- Duckworth Nichola
- Dudek Monika
- Durham Jillian
- Durrant Laura
- Easthope Elizabeth
- Eastick Kirstine
- Easton Lisa J
- Eccles Richard
- Eckert Sabine
- Edgeworth Jonathan
- Edwards Sue
- El Bouzidi Kate
- Eldirdiri Sahar
- Ellaby Nicholas
- Elliott Scott
- Ellis Pete
- Eltringham Gary
- Ensell Leah
- Erkiert Michelle J
- Essex Sarah
- Evans Cariad
- Evans Johnathan M
- Everson William
- Fairley Derek J
- Fallon Karlie
- Fanaie Arezou
- Farr Ben
- Farr Ben W
- Fearn Christopher
- Feltwell Theresa
- Fenton Michael
- Ferguson Lynne
- Ferrero Marcella
- Fina Laia
- Flack Neil
- Flaviani Flavia
- Fleming Vicki M
- Fordham Howerd
- Forrest Sally
- Forsythe Grace
- Foster-Nyarko Ebenezer
- Foulkes Benjamin H
- Foulser Luke
- Fragakis Mireille
- Frampton Dan
- Francis Matt
- Francois Sarah
- Fraser Audrey
- Fraser Christophe
- Freeman Adam
- Freeman Timothy M
- Fryer Helen
- Fuchs Marc
- Fuller William
- Funk Sebastian
- Gajee Kavitha
- Galai Katerina
- Gallagher Abbie
- Gallagher Eileen
- Gallagher Michael D
- Gallis Marta
- Galvin Anastasia
- Garcia-Casado Maria
- Gaskin Amy
- Gatica-Wilcox Bree
- Gedny Alex
- Geidelberg Lily
- Gemmell Matthew
- Georgana Iliana
- George Ryan P
- Gerstung Moritz
- Gifford Laura
- Gilbert Lauren
- Girgis Sophia
- Girgis Sophia T
- Glaysher Sharon
- Glover James
- Goater Richard
- Goldman Nick
- Goldstein Emily J
- Golubchik Tanya
- Gomes Andrea N
- Goncalves Sonia
- Gonçalves Sonia
- Gonçalves Sónia
- Goodfellow Ian G
- Goodwin Scott
- Goudarzi Salman
- Gould Oliver
- Gourtovaia Marina
- Graham Clive
- Graham Lee
- Grant Paul R
- Gray Andy
- Gray Emma
- Green Angie
- Green Luke R
- Greenaway Jane
- Gregory Richard
- Griffiths Coline
- Gu Yong
- Guerin Florence
- Guest Martyn
- Gunson Rory N
- Gupta Ravi K
- Gutierrez Bernardo
- Haldenby Sam T
- Hamilton Will
- Hamilton William L
- Hanks Hannah
- Hansford Samantha E
- Haque Tanzina
- Harris Kathryn A
- Harrison Ewan
- Harrison Ewan M
- Harrison Ian
- Harrott Alexandria
- Harry Edward
- Hart Jennifer
- Hartley John A
- Harvey Matthew
- Harvey William T
- Harvison Julia
- Hassan-Ibrahim Mohammed O
- Heaney Judith
- Heath Paul
- Hellewell Joel
- Helmer Thomas
- Henderson John H
- Hernandez-Koutoucheva Anastasia
- Hesketh Andrew R
- Hey Jessica
- Heyburn David
- Higginson Ellen E
- Hill Jack D
- Hill Verity
- Hilson Rachel A
- Hilvers Ember
- Hobbs Rhiannon
- Holden Matthew TG
- Holland Dave
- Hollis Amy
- Holmes Alison H
- Holmes Christopher W
- Holmes Nadine
- Holmes Sarah
- Hopes Richard
- Hornett Gary
- Hornsby Hailey R
- Hosmillo Myra
- Hough Nicholas
- Houlihan Catherine
- Howson-Wells Hannah C
- Hsu Sharon N
- Hubb Jonathan
- Huckle Liz
- Huckson Hannah
- Hughes Joseph
- Hughes Margaret
- Hughes Warwick
- Hughes-Hallet Lena
- Hunter Adam
- Hutchings Stephanie
- Idle Giles
- Illingworth Chris J
- Impey Robert
- Inglis Stephen
- Iqbal Sameena
- Irish-Tavares Dianne
- Iturriza-Gomara Miren
- Izuagbe Rhys
- Jackson Adam
- Jackson Ben
- Jackson Chris
- Jackson David
- Jackson David K
- Jackson Kathryn A
- Jackson Leigh M
- Jahun Aminu S
- James Keith
- James Victoria
- Jamrozy Dorota
- Jeanes Christopher
- Jeffries Aaron R
- Jeremiah Sarah
- Jermy Andrew
- John Michaela
- Johnson Kate
- Johnson Rob
- Johnston Ian
- Jones Christopher R
- Jones Hannah
- Jones Matthew
- Jones Neil
- Jones Owen
- Jones Sophie
- Joseph Amelia
- Judges Sarah
- Jung Alexander W
- Kallepally Kalyan
- Kane Leanne
- Kay Gemma L
- Kay Keely
- Kay Sally
- Keatley Jon
- Keatley Jon-Paul
- Keeley Alexander J
- Keith Alan
- Kenyon Anita
- Kermack Leanne M
- Khakh Manjinder
- Kidd Stephen P
- Kimuli Maimuna
- King Alison
- Kirk Stuart
- Kitchen Christine
- Kitchin Lucy
- Kitchman Katie
- Kleanthous Matt
- Klimekova Martina
- Knight Bridget A
- Korlevic Petra
- Koshy Cherian
- Kraemer Moritz UG
- Krasheninnkova Ksenia
- Kumziene-Summerhayes Sara
- Kwiatkowski Dominic
- Kwiatkowski Dominic
- Lackenby Angie
- Laing Kenneth G
- Lampejo Temi
- Lane Greg
- Langford Cordelia
- Langford Cordelia F
- Laverack Adam
- Lavin Deborah
- Law Katharine
- Lawniczak Mara
- Lawton Andrew I
- Le-Viet Thanh
- Lee David
- Lee Jack CD
- Lensing Stefanie
- Lensing Stefanie V
- Leonard Steven
- Letchford Laura
- Levett Lisa J
- Lewis Jonathan
- Lewis Kevin
- Lewis-Wade Amanah
- Liddle Jennifer
- Liddle Jennifier
- Liggett Steven
- Lillie Patrick J
- Lin Quan
- Lindsay Sarah
- Lindsey Benjamin B
- Linsdell Sally
- Lister Michelle M
- Livett Rich
- Lo Stephanie
- Loman Nicholas J
- Long Rhona
- Loose Matthew W
- Louka Stavroula F
- Lovell Jamie
- Lovell Jon
- Loveson Katie F
- Lowdon Sarah
- Lowe Hannah
- Lowe Helen L
- Lucaci Anita O
- Ludden Catherine
- Ludden Catherine
- Lynch Jessica
- Lyons Ronan A
- Lythgoe Katrina
- Machin Nicholas W
- MacIntyre-Cockett George
- Mack Andrew
- Mack James
- Macklin Ben
- Maclean Alasdair
- Macnaughton Emily
- Maddison Mark
- Madona Pinglawathee
- Maes Mailis
- Maftei Laurentiu
- Mahanama Adhyana IK
- Mahungu Tabitha W
- Mair Daniel
- Maksimovic Joshua
- Makunin Aleksei
- Malone Cassandra S
- Maloney Daniel
- Mamun Irfan
- Manesis Nikos
- Manley Robin
- Mansfield Jenny
- Mantzouratou Anna
- Marchbank Angela
- Mariappan Arun
- Marriott Neil
- Martin Matt
- Martincorena Inigo
- Martinez Nunez Rocio T
- Masters Kathryn McCluggage
- Mather Alison E
- Maxwell Patrick
- Mayhew Megan
- Mayho Matthew
- Mbisa Tamyo
- McCann Clare M
- McCarthy Shane
- McCarthy Shane A
- McClintock Jo
- McClure Patrick C
- McCrone JT
- McGuigan Samantha
- McHugh Martin P
- McHugh Sandra
- McKenna James P
- McKerr Caoimhe
- McManus Georgina M
- McMinn Liz
- McMurray Claire
- McMurray Claire L
- McNally Alan
- Meadows Carl
- Meadows Lizzie
- Medd Nathan
- Megram Oliver
- Menegazzo Mirko
- Merrick Ian
- Michell Stephen L
- Michelsen Michelle L
- Mirfenderesky Mariyam
- Mirza Jeremy
- Miskelly Julia
- Mobley Emily
- Moles-Garcia Emma
- Moll Robin
- Moll Robin J
- Molnar Zoltan
- Monahan Irene M
- Mondani Matteo
- Monteiro Tiago Carvalho
- Mookerjee Siddharth
- Moore Catherine
- Moore Christopher
- Moore Jonathan
- Moore Nathan
- Morcrette Helen
- Morgan Mari
- Morgan Sian
- Mori Matilde
- Morra Maria
- Morriss Arthur
- Morrow Leanne
- Moses Samuel
- Mower Craig
- Muir Peter
- Mukaddas Afrida
- Munemo Florence
- Munn Robert
- Murie Kathryn
- Murray Abigail
- Murray Darren R
- Murray Leanne J
- Mutingwende Manasa
- Myers Richard
- Nash Sian
- Nastouli Eleni
- Nathwani Claire
- Naydenova Plamena
- Neaverson Alexandra
- Nebbia Gaia
- Nelson Andrew
- Nelson Charlotte
- Nelson Rachel
- Nerou Ed
- Nguyen Thuy
- Nicholls Sam
- Nichols Jenna
- Nicholson Jon
- Nicodemi Roberto
- Nimz Tabea
- Noell Guillaume G
- Nomikou Kyriaki
- Odedra Mina
- Ohan Valeriu
- Ohemeng-Kumi Natasha
- Oliver Karen
- Olney Charles
- Ormond Doug
- Orton Richard J
- Osman Husam
- Oszlanczi Agnes
- OâBrien Sarah
- OâGrady Justin
- OâMeara Sarah
- OâToole Ăine
- Pacchiarini Nicole
- Padgett Debra
- Page Andrew J
- Palmer Steve
- Pang Yoke Fei
- Panovska-Griffiths Jasmina
- Pardubska Barbora
- Park Emily J
- Park Naomi
- Park Naomi R
- Parker Matthew D
- Parmar Aaron
- Parmar Surendra
- Partridge David G
- Pascall David
- Patel Amita
- Patel Bindi
- Patel Gaurang
- Patel Minal
- Paterson Steve
- Payne Brendan AI
- Payne Maggie
- Peacock Sharon
- Peacock Sharon J
- Pearson Clare
- Pelosi Emanuela
- Percival Benita
- Perkins Jon
- Perry Malorie
- Petersen Arabella
- Pinckert Malte L
- Platt Steven
- Plowman Deborah
- Podplomyk Olga
- Pohare Manoj
- Pond Marcus
- Pope Cassie F
- Poplawski Radoslaw
- Powell Jessica
- Poyner Jennifer
- Preston Tom
- Prestwood Liam
- Price Anna
- Price James R
- Prieto Jacqui A
- Pritchard David T
- Prosolek Sophie J
- Puethe Christoph
- Pugh Georgia
- Pusok Monika
- Pybus Oliver G
- Pymont Hannah M
- Quail Michael
- Quail Michael A
- Quick Joshua
- Radulescu Clara
- Raghwani Jayna
- Ragonnet-Cronin Manon
- Rainbow Lucille
- Rajan Diana
- Rajatileka Shavanthi
- Ramadan Newara A
- Rambaut Andrew
- Ramble John
- Rance Richard
- Randell Paul
- Randell Paul A
- Ratcliffe Liz
- Raviprakash Veena
- Rawlings Suzannah
- Raza Mohammad
- Redshaw Nicholas
- Redshaw Nicholas M
- Rey Sara
- Reynolds Joe
- Reynolds Mark
- Reynolds Nicola
- Rice Simon
- Richardson Matt
- Richter Alex
- Roberts Connor
- Robertson David L
- Robinson David
- Robinson Esther
- Robinson Katrina
- Robinson Melanie
- Robson Samuel C
- Rogan Fiona
- Rogers Hazel
- Rojo Eduardo Martin
- Rooke Stefan
- Roopra Daljit
- Rose Mark
- Rowe Will
- Roy Sunando
- Rudd Luke
- Rudder Steven
- Ruis Chris
- Rushton Steven
- Sadri Ramin
- Saeed Kordo
- Saint Callum
- Salmon Nicholas
- Samaraweera Buddhini
- Sambles Christine M
- Sanderson Roy
- Sanderson Theo
- Sanderson Theo
- Sang Fei
- Sass Thea
- Saul David
- Scher Emily
- Schwach Frank
- Schwach Frank
- Scott Carol
- Scott Garren
- Seekings Phil
- Sehmi Jasveen
- Shaaban Sharif
- Shah Divya
- Shaw Jessica
- Shelest Ekaterina
- Shepherd James G
- Sheridan Liz A
- Sheriff Nicola
- Shirley Lesley
- Sillitoe John
- Silviera Siona
- Simms Alison
- Simpson David A
- Singh Aditi
- Singleton Dawn
- Sinnott Matthew
- Sinnott Matthew
- Sivadasan Shanthi
- Siwek Bart
- Sizer Dale
- Skeldon Kenneth
- Skelton Jason
- Skvortsov Timofey
- Slater-Tunstill Joanna
- Sloan Tim J
- Sloper Lisa
- Sluga Graciela
- Smerdon Nathalie
- Smith Chris
- Smith Christen
- Smith Colin P
- Smith Darren L
- Smith James
- Smith Katie
- Smith Ken
- Smith Kim S
- Smith Louise
- Smith Michelle
- Smith Nikki
- Smith Perminder
- Smith Sean
- Smith Tina
- Smollett Katherine L
- Sneade Leighton
- Snell Luke B
- Somassa Thomas
- Soria Carmen Diaz
- Sousa Catarina
- Souster Emily
- Southgate Joel
- Sparkes Andrew
- Spellman Karla
- Spencer Chapman Michael H
- Spencer-Chapman Michael
- Spurgin Lewis G
- Spyer Moira J
- Squares Janet
- Stanley Rachael
- Stanley Robert
- Stanley William
- Stanton Thomas D
- Starinskij Igor
- Steed Claire
- Stickland Tim
- Still Ian
- Stockton Joanne
- Stonehouse Susanne
- Storey Nathaniel
- Stratton Michael R
- Strickland Michelle
- Studholme David J
- Suciu Maria
- Sudhanva Malur
- Swann Allen
- Swiatkowska Agnieszka
- Swift Emma
- Swindells Emma
- Sycamore Neil
- Symons Edward
- Szluha Suzanne
- Taha Yusri
- Taluy Emma
- Tan Ngee Keong
- Tang Julian W
- Tang Miao
- Tao Nunu
- Taylor Ben EW
- Taylor Joshua F
- Taylor Katy
- Taylor Sam
- Taylor Sarah
- Temperton Ben
- Templeton Kate E
- Thomas Claire
- Thompson Mark
- Thompson Stacey
- Thomson Emma C
- Thomson Laura
- Thomson Mark
- Thomson Nicholas
- Thornton Alicia
- Thurston Scott
- Thurston Scott AJ
- Todd John A
- Tomb Rachael
- Tong Lily
- Tonkin-Hill Gerry
- Toombs Dee
- Topping Benjamin
- Torok M Estee
- Tovar-Corona Jaime
- Tovar-Corona Jaime M
- Trebes Amy
- Trotter Alexander J
- Tsatsani Ioulia
- Turnbull Robyn
- Turtle Lance
- Twohig Katherine A
- Umpleby Helen
- Underwood Anthony P
- Ungureanu Daniel
- Uphill James
- Urbanova Jana
- Vamos Edith E
- Van Vuuren Philip Jansen
- Vancollie Valerie
- Vasylyeva Tetyana I
- Vattipally Sreenu
- Verdejo Carlos Jimenez
- Vernet Gabrielle
- Vipond Barry B
- Voak Paul
- Volz Erik
- Volz Erik M
- Vöhringer Harald S
- Walker Danielle
- Walker Matthew
- Waller Matt
- Walsh Sarah
- Wang Dennis
- Ward Gary
- Warne Ben
- Warwick-Dugdale Joanna
- Wastnedge Elizabeth
- Watkins Joanne
- Watson Louisa K
- Waugh Sheila
- Weatherhogg Charlie
- Webb Niki
- Webster Hermione J
- Weldon Danni
- Wells Alan
- Wells Eloise
- Westwick Elaine
- Westwood Luke
- Whalley Thomas
- Wheeler Helen
- Whipp Theo
- Whitehead Mark
- Whiteley Max
- Whiteley Thomas
- Whitton Georgia
- Whitwham Andrew
- Widaa Sara
- Wierzbicki Claudia
- Willford Nicholas J
- Williams Catryn
- Williams Charlotte A
- Williams Cheryl
- Williams Chris
- Williams Lesley-Anne
- Williams Mia
- Williams Rachel J
- Williams Rebecca
- Williams Thomas
- Williamson Kathleen A
- Wilson Mark
- Wilson-Davies Eleri
- Witele Eric
- Withell Karen T
- Witney Adam A
- Wolverson Paige
- Wong Nick
- Workman Trudy
- Wright Derek W
- Wright Sean
- Wright Victoria
- Wyatt Tim
- Wyllie Sarah
- Xu-McCrae Li
- Yavus Mehmet
- Yaze Geraldine
- Yeats Corin A
- Yebra Gonzalo
- Yew Wen C
- Young Gregory R
- Young Jamie
- Zamudio Marina Escalera
- Zarebski Alex E
- Zhang Peijun
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 14/10/2021
- Field of study
AbstractThe evolution of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus leads to new variants that warrant timely epidemiological characterization. Here we use the dense genomic surveillance data generated by the COVID-19 Genomics UK Consortium to reconstruct the dynamics of 71 different lineages in each of 315 English local authorities between September 2020 and June 2021. This analysis reveals a series of subepidemics that peaked in early autumn 2020, followed by a jump in transmissibility of the B.1.1.7/Alpha lineage. The Alpha variant grew when other lineages declined during the second national lockdown and regionally tiered restrictions between November and December 2020. A third more stringent national lockdown suppressed the Alpha variant and eliminated nearly all other lineages in early 2021. Yet a series of variants (most of which contained the spike E484K mutation) defied these trends and persisted at moderately increasing proportions. However, by accounting for sustained introductions, we found that the transmissibility of these variants is unlikely to have exceeded the transmissibility of the Alpha variant. Finally, B.1.617.2/Delta was repeatedly introduced in England and grew rapidly in early summer 2021, constituting approximately 98% of sampled SARS-CoV-2 genomes on 26 June 2021.</jats:p
Deep Underground Neutrino Experiment (DUNE), Far Detector Technical Design Report, Volume II: DUNE Physics
- Author
- Abi Babak
- Acciarri Roberto
- Acero Mario
- Adamov Giorge
- Adams David
- Adinolfi Marco
- Ahmad Zubayer
- Ahmed Jhanzeb
- Alion Tyler
- Alonso Monsalve Saul
- Alt Christoph
- Anderson John
- Andreopoulos Costas
- Andrews Michael P
- Andriamirado Manoa
- Andrianala Fenompanirina
- Andringa Sofia
- Ankowski Artur
- Anthony Jack
- Antoniu Iliescu
- Antonova Maria
- Antusch Stefan
- Aranda Fernandez Alfredo
- Ariga Akitaka
- Arnold Lukas
- Arroyave Manuel
- Asaadi Jonathan
- Aurisano Adam
- Aushev Vladimir
- Autiero Dario
- Azfar Farrukh
- Back Ashley
- Back Henning
- Back John
- Backhouse Chris
- Baesso Paolo
- Bagby Linda
- Bajou Raphael
- Balasubramanian Supraja
- Baldi Pierre
- Bambah Bindu
- Barao Fernando
- Barenboim Gabriela
- Barker Gary J
- Barkhouse Wayne
- Barnes Christopher
- Barr Giles
- Barranco Monarca Juan
- Barros Nuno
- Barrow Joshua
- Bashyal Amit
- Basque Vincent
- Bay Fatih
- Bazo Alba J.L.
- Beacom John
- Bechetoille Edouard
- Behera Biswaranjan
- Bellantoni Leo
- Bellettini Giorgio
- Bellini Vincenzo
- Beltramello Olga
- Belver D.
- Benekos Nektarios
- Bento Neves Francisco
- Berger Joshua
- Berkman Sophie
- Bernardini Paolo
- Berner Roman
- Berns Hans-Gerd
- Bertolucci Sergio
- Betancourt Minerba
- Bezawada Y.
- Bhattacharjee maharnab
- Bhuyan Bipul
- Biagi Simone
- Bian Jianming
- Biassoni Matteo
- Biery Kurt
- Bilki Burak
- Bishai Mary
- Bitadze Alexander
- Blake Andrew
- Blanco Siffert Beatriz
- Blaszczyk Flor de Maria
- Blazey Gerald C
- Blucher Edward
- Boissevain Jan
- Bolognesi Sara
- Bolton Timothy
- Bonesini Maurizio
- Bongrand Mathieu
- Bonini Filiberto
- Booth Alexander
- Booth Chris
- Bordoni Stefania
- Borkum Aran
- Boschi Tommaso
- Bostan Nilay
- Bour Petr
- Boyd Steve B
- Boyden Daniel
- Bracinik Juraj
- Braga Davide
- Brailsford Dominic
- Brandt Andrew
- Bremer Johan
- Brew Chris
- Brianne Eldwan
- Brice Stephen
- Brizzolari Claudia
- Bromberg Carl
- Brooijmans Gustaaf
- Brooke Jim
- Bross Alan
- Brunetti Giulia
- Buchanan Norman
- Budd Howard
- Caiulo Davide
- Calafiura Paolo
- Calcutt Jacob
- Calin Marius
- Calvez Steven
- Calvo Enrique
- Camilleri Leslie
- Caminata Alessio
- Campanelli Mario
- Caratelli David
- Carini Gabriella
- Carlus Bruno
- Carniti Paolo
- Caro Terrazas Ivan
- Carranza Hector
- Castillo Andrés
- Castromonte Cesar
- Cattadori Carla
- Cavalier Fabien
- Cavanna Flavio
- Centro Sandro
- Cerati Giuseppe
- Cervelli Alberto
- Cervera Villanueva Anselmo
- Chalifour Michel
- Chang C.
- Chardonnet Etienne
- Chatterjee Animesh
- Chattopadhyay Subhasish
- Chaves Jorge
- Chen Hucheng
- Chen Mu-Chun
- Chen Yifan
- Cherdack Daniel
- Chi Cheng-Yi
- Childress Sam
- Chiriacescu Ana
- Cho Kihyeon
- Choubey Sandhya
- Christensen Anne
- Christian David
- Christodoulou Georgios
- Church Eric
- Clarke Peter
- Coan Thomas
- Cocco Alfredo
- Coelho Joao
- Conley Erin
- Conrad Janet M
- Convery Mark
- Corwin Luke
- Cotte Philippe
- Cremaldi Lucien
- Cremonesi Linda
- Crespo-AnadĂłn Jose I
- Cristaldo Esteban
- Cross Ryan
- Cuesta Clara
- Cui Yanou
- Cussans David
- Da Motta Helio
- Dabrowski Mieczyslaw
- David Quentin
- Davies Gavin
- Davini Stefano
- Dawson Jaime
- de Almeida Rogerio
- De Bonis Isabelle
- de Gouvea Andre
- de Holanda Pedro
- de Icaza Astiz Iker
- De Jong Paul
- De Lurgio Patrick
- De Roeck Albert
- De Romeri Valentina
- De Kaushik
- Debbins Paul
- Decowski M Patrick
- Deisting Alexander
- Delbart Alain
- Delepine David
- Delgado Maritza
- Dell'Acqua Andrea
- DeMuth David
- Dennis Steve
- Densham Chris
- Dharmapalan Ranjan
- Di Domizio Sergio
- Di Giulio Letizia
- Di Noto Lea
- Diaz Felix
- Diaz Jorge S
- Ding Pengfei
- Distefano Carla
- Diurba Richard
- Diwan Milind
- Djurcic Zelimir
- Dokania Neha
- Dolinski Michelle J
- Domine Laura
- Douglas Daniel
- Drielsma Francois
- Duchesneau Dominique
- Duffy Kirsty
- Dunne Patrick
- Durkin Tim
- Duyang Hongyue
- Dvornikov Olexiy
- Dwyer Daniel A
- Dyshkant Alexandre S
- Eads Michael
- Edmunds Daniel
- Eisch Jonathan
- Emery Sandrine
- Ereditato Antonio
- Escobar Carlos O
- Escudero Sanchez Lorena
- Evans Justin
- Ewart E.
- Ewart Kevin
- Ezeribe Anthony
- Fahey Kevin
- Falcone Andrea
- Farnese Christian
- Farzan Yasaman
- Felix Julian
- Fernandez Menendez Pablo
- Fernandez-Martinez Enrique
- Ferraro Federico
- Fields Laura
- Filkins A.
- Filthaut Frank
- Fitzpatrick Rory
- Flanagan Will
- Fleming Bonnie
- Flight Robert
- Fowler Jack
- Fox Walt
- Franc Jiri
- Francis Kurt
- Franco Domenico
- Freeman John
- Freestone Julian
- Fried Jack
- Friedland Alex
- Fuess Stu
- Furic Ivan
- Furmanski Andrew
- Gago A.
- Gallagher Hugh
- Gallego-Ros Ana
- Gallice Niccolo
- Galymov Vyacheslav
- Gamberini Enrico
- Gamble Trevor
- Gandhi Raj
- Gandrajula Reddy
- Gao Shanshan
- Garcia-Gamez Diego
- GarcĂa-Peris Miguel
- Gardiner Steven
- Gastler Dan
- Ge Guanqun
- Gelli Bruno
- Gendotti Adamo
- Gent Stephen
- Ghorbani-Moghaddam Zahra
- Gibin Daniele
- Gil-Botella Ines
- Girerd Claude
- Giri Anjan Kumar
- Gnani D.
- Gogota Olga
- Gold Michael
- Gollapinni Sowjanya
- Gollwitzer Keith
- Gomes Ricardo
- Gomez Bermeo Laura Vanessa
- Gomez Fajardo Luz
- Gonnella Francesco
- Gonzalez-Cuevas Juan Alberto
- Goodman Maury
- Goodwin Owen
- Goswami Srubabati
- Gotti Claudio
- Goudzovski Evgueni
- Grace Carl
- Graham Mathew
- Gramellini E.
- Gran Rik
- Granados Everardo
- Grant Alan
- Grant Christopher
- Grant Nick
- Gratieri Diego
- Green Patrick
- Green Steven
- Greenler Leland
- Greenwood M.
- Greer Joel
- Gregor Recalde Derlis
- Griffith Clark
- Groh Micah
- Grudzinski James
- Grzelak Katarzyna
- Gu Wenqiang
- Guarino Victor
- Guenette Roxanne
- Guglielmi Alberto
- Guo Bing
- Guthikonda K K
- Gutierrez Rafael
- Guzowski Pawel
- Guzzo Marcelo
- Gwon Sunwoo
- Habig Alec
- Hackenburg A.
- Hadavand Haleh
- Haenni Roger
- Hahn Alan
- Haigh Jennifer
- Haiston James
- Hamernik Thomas
- Hamilton Philip
- Han Jiyeon
- Harder Kristian
- Harris Debbie
- Hartnell Jeffrey
- Hasegawa Takyua
- Hatcher Robert
- Hazen Eric
- Heavey Anne
- Heeger Karsten
- Hennessy Karol
- Henry Sarah
- Hernandez Morquecho Miguel Angel
- Herner Kenneth
- Hertel Lars
- Hewes Jeremy
- Hewes V.
- Higuera Pichardo Aaron
- Hill Tony
- Hillier Stephen
- Himmel Alexander
- Hoff James
- Hohl Christian
- Holin Anna
- Hoppe Eric
- Horton-Smith Glenn
- Hostert Matheus
- Hourlier Adrien
- Howard Bruce
- Howell Ryan
- Huang Junting
- Huang Junying
- Hugon Justin
- Iles Gregory
- Illingworth Robert
- Ioannisian Ara
- Itay Ran
- Izmaylov Alexander
- James Eric
- Jan De Vries Joris
- Jargowsky B.
- Jediny Filip
- JesĂșs-Valls CĂ©sar
- Ji Xiangpan
- Jiang L.
- Jiménez Sergio
- Jipa Alexandru
- Johnson Connor
- Johnson Randy
- Jones Benjamin
- Jones Sebastian
- Jung Chang Kee
- Junk Thomas
- Jwa Yeon-jae
- Kabirnezhad Monireh
- Kaboth Asher
- Kadenko I
- Kamiya Felipe
- Karagiorgi Georgia
- Karcher A.
- Karolak Mark
- Karyotakis Yannis
- Kasai Seiji
- Kasetti Siva
- Kashur Lane
- Kazaryan Narine
- Kearns Edward
- Keener Paul
- Kelly Kevin
- Kemp Ernesto
- Ketchum Wes
- Kettell Steve H
- Khabibullin Marat
- Khotjantsev Alexei
- Khvedelidze Arsen
- Kim D.
- King Bonnie
- Kirby Brian
- Kirby Mike
- Klein Joshua
- Koehler Kevin
- Koerner Lisa
- Kohn Sam
- Koller Patrick
- Kordosky Mike
- Kosc Thomas
- Kose Umut
- Kostelecky V Alan
- Kothekar Kunal
- Krennrich Frank
- Kreslo Igor
- Kudenko Yury
- Kudryavtsev Vitaly A
- Kulagin Sergey
- Kumar Jason
- KUMAR Rajeev
- Kuruppu Chatura
- Kus Vaclav
- Kutter Thomas
- Lambert A.
- Lande Kenneth
- Lane Charles
- Lang Karol
- Langford Thomas
- Lasorak Pierre
- Last David
- Lastoria Chiara
- Laundrie Andy
- Lawrence A.
- Lazanu Ionel
- LaZur Ryan
- Le Trung
- Learned John
- LeBrun Patrice
- Lehmann Miotto Giovanna
- Lehnert Ralf
- Leigui de Oliveira M A
- Leitner M.
- Leyton Michael
- Li Lingge
- Li Shaorui
- Li Shirley W
- Li Teng
- Li Yichen
- Liao Heng-Ye
- Lin Cheng-Ju Stephen
- Lin Shih-Kai
- Lister Adam
- Littlejohn Bryce
- Liu J.
- Lockwitz Sarah
- Loew Timothy
- Lokajicek Milos
- Lomidze Irakli
- Long Ken
- Loo Kai
- Lorca David
- Lord Tom
- LoSecco John M
- Louis William
- Luk Kam-Biu
- Luo Xiao
- Lurkin Nicolas
- Lux Thorsten
- Luzio Vitor Prestes
- MacFarlane David
- Machado Ana Amelia
- Machado Pedro
- Macias Christopher Thomas
- Macier Jolie R
- Maddalena Antonello
- Madigan Peter
- Magill Steve
- Mahn Kendall
- Maio AmeÌlia
- Maloney James
- Mandrioli Gianni
- Maneira José
- Manenti Laura
- Manly Steve
- Mann Anthony
- Manolopoulos Konstantinos
- Manrique Plata Maria
- Marchionni Alberto
- Marciano William
- Marfatia Danny
- Mariani Camillo
- Maricic Jelena
- Marinho Franciole
- Marino Alysia
- Marshak Marvin
- Marshall Chris
- Marshall John
- Marteau Jacques
- Martin-Albo Justo
- Martinez Caicedo David
- Martinez Norman
- Martynenko Sergey
- Mason Katie
- Mastbaum Andrew
- Masud Mehedi
- Matsuno Shigenobu
- Matthews James
- Mauger Christopher
- Mauri Nicoletta
- Mavrokoridis Konstantinos
- Mazza Roberto
- Mazzacane Anna
- Mazzucato Edoardo
- McCluskey Elaine
- McConkey Nicola
- McFarland Kevin
- McGrew Clark
- McNab Andrew
- Mefodiev Alexander
- Mehta Poonam
- Melas Pantelis
- Mellinato Michele
- Mena Olga
- Menary Scott
- Mendes Santos Lucas
- Mendez Hector
- Menegolli A
- Meng Guang
- Messier Mark
- Metcalf William
- Mewes Matthew
- Meyer Holger
- Miao Ting
- Michna Gregory
- Miedema Thijs
- Migenda Jost
- Milincic Radovan
- Miller William H.
- Mills Joshua
- Milne Cody
- Mineev Oleg
- Miranda Omar
- Miryala Sandeep
- Mishra C Shekhar
- Mishra Sanjib R
- Mislivec Aaron
- Mladenov Dimitar
- Mocioiu Irina
- Moffat Kristian
- Moggi Niccolo
- Mohanta Rukmani
- Mohayai Tanaz
- Mokhov Nikolai
- Molina Bueno Laura
- Molina Jorge
- Montanari Alessandro
- Montanari Claudio
- Montanari David
- Montano Zetina Luis
- Moon Jarrett
- Mooney Michael
- Moreno Deywis
- Morgan Ben
- Morris Casandra
- Mossey Chris
- Motuk Erdem
- Moura CĂ©lio
- Mousseau Joel
- Mu Wei
- Mualem Leon
- Mueller Justin
- Muether Mathew
- Mufson Stuart
- Muheim Franz
- Muir Alan
- Mulhearn Mike
- Muramatsu Hajime
- Murphy Sebastien
- Musser Jim
- Nachtman Jane
- Nagu S.
- Nalbandyan Mikayel
- Nandakumar Raja
- Naples Donna
- Narita Shinya
- Navas-Nicolas D.
- Nayak Nitish
- Nebot-Guinot Miquel
- Necib Lina
- Negishi Kentaro
- Nelson Jeff
- Nesbit Jake
- Nessi Marzio
- Newbold David
- Newcomer Mitch
- Newhart Duane
- Nichol Ryan
- Niner Evan
- Nishimura Kurtis
- Norman Andrew
- Northrop Rich
- Novella Pau
- Nowak Jaroslaw
- Oberling Michael
- Olivares Del Campo Andres
- Olivier Andrew
- Onel Yasar
- Onishchuk Yuriy
- Ott Jordan
- Pagani Luca
- Pakvasa Sandip
- Palamara Ornella
- Palestini Sandro
- Paley Jonathan
- Pallavicini Marco
- Palomares Carmen
- Pantic Emilija
- Paolone Vittorio
- Papadimitriou Vaia
- Papaleo Riccardo
- Papanestis Antonis
- Paramesvaran Sudarshan
- Parke Stephen
- Parsa Zohreh
- Parvu Mihaela
- Pascoli Silvia
- Pasqualini Laura
- Pasternak Jaroslaw
- Pater Joleen
- Patrick Cheryl
- Patrizii Laura
- Patterson Ryan
- Patton Simon John
- Patzak Thomas
- Paudel Ajib
- Paulos Bob
- Paulucci Laura
- Pavlovic Zarko
- Pawloski Greg
- Payne David
- Pec Viktor
- Peeters Simon
- Penichot Yves
- Pennacchio Elisabetta
- Penzo Aldo
- Peres L. Da Silva
- Peres Orlando
- Perry James
- Pershey Daniel
- Pessina Gianluigi
- Petrillo Gianluca
- Petta Catia
- Petti Roberto
- Piastra Francesco
- Pickering Luke
- Pietropaolo Francesco
- Pillow James
- Plunkett Robert
- Poling Ronald
- Pons Xavier
- Poonthottathil Navaneeth
- Pordes Stephen
- Potekhin Maxim
- Potenza Renato
- Potukuchi B.V.K.S.
- Pozimski Juergen
- Pozzato Michele
- Prakash Suprabh
- Prakash Tarun
- Prince Sebastien
- Pugnere Denis
- Qi K.
- Qian Xin
- Raaf Jennifer L
- Raboanary R.
- Radeka Veljko
- Rademacker Jonas
- Radics Balint
- Rafique Aleena
- Raguzin Eric
- Rai Mousam
- Rajaoalisoa Miriama
- Rakhno Igor
- Rakotondramanana H.T.
- Rakotondravohitra Laza
- Ramachers Yorck A
- Rameika Regina
- Ramirez Delgado Manuel Alejandro
- Ramson Bryan
- Rappoldi A
- Raselli GL
- Ratoff Peter
- Ravat Sylvain
- Razafinime H.
- Real Jean-Sebastien
- Rebel Brian
- Redondo David
- Reggiani-Guzzo Marina
- Rehak Tyler
- Reichenbacher Juergen
- Reitzner S
- Renshaw Andrew
- Rescia Sergio
- Resnati Filippo
- Reynolds Aidan
- Riccobene Giorgio
- Rice Logan
- Rielage Keith
- Rigaut Yann-Axel
- Rivera David
- Rochester Leon
- Roda Marco
- Rodrigues Philip
- Rodriguez Alonso Manual Jesus
- Rodriguez Rondon Jairo
- Roeth Alison J
- Rogers Hannah
- Rosauro-Alcaraz Salvador
- Rossella M
- Rout Jogesh
- Roy Samiran
- Rubbia Andre
- Rubbia Carlo
- Russell Brooke
- Russell James
- Ruterbories Daniel
- Saakyan Ruben
- Sacerdoti Sabrina
- Safford Twymun
- Sahu Narendra
- Sala Paola
- Samios Nicholas
- Sanchez Mayly
- Sanders David
- Sankey David
- Santana Samuel
- Santos-Maldonado Marvin
- Saoulidou Niki
- Sapienza Piera
- Sarasty Carlos
- Sarcevic Ina
- Savage Geoffrey
- Savinov Vladimir
- Scaramelli Alberto
- Scarff Andrew
- Scarpelli Andrea
- Schaffer Tom
- Schellman Heidi
- Schlabach Philip
- Schmitz David
- Scholberg Kate
- Schukraft Anne
- Segreto Ettore
- Sensenig Jon
- Seong Ilsoo
- Sergi Antonino
- Sergiampietri F.
- Sgalaberna Davide
- Shaevitz Michael H
- Shafaq Sheeba
- Shamma M.
- Sharma Hans
- Sharma Rahul
- Shaw Terri
- Shepherd-Themistocleous Claire
- Shin Seodong
- Shooltz Dean
- Shrock Robert
- Simard Laurent
- Simos Nikolaos
- Sinclair James
- Sinev Gleb
- Singh Jaydip
- Singh Jyotsna
- Sipos Roland
- Sippach F W
- Sirri Gabriele
- Sitraka Andriaseta
- Siyeon Kim
- Smargianaki D.
- Smith Adryanna
- Smith Andrew
- Smith Erica
- Smith Paul
- Smolik Jan
- Smy Michael
- Snopok Pavel
- Soares Nunes MĂŽnica
- Sobel Henry
- Soderberg Mitch
- Solano Salinas Carlos
- Solomey Nicholas
- Solovov Vladimir
- Sondheim Walter
- Sorel Michel
- Soto-Oton Jose
- Sousa Alexandre
- Soustruznik Karel
- Spagliardi Fabio
- Spanu Maura
- Spitz Joshua
- Spooner Neil JC
- Spurgeon Kyle
- Staley Richard
- Stancari Michelle
- Stanco Luca
- Steiner Herbert M
- Stewart James
- Stillwell Ben
- Stock Jason
- Stocker Francesca
- Stokes Tyler
- Strait Matthew
- Strauss Thomas
- Striganov Sergei
- Stuart Alexander
- Summers Don
- Surdo Antonio
- Susic Vasja
- Suter Louise
- Sutera Concetta Maria
- Svoboda Robert
- Szczerbinska Barbara
- Szelc Andrzej
- Söldner-Rembold Stefan
- Talaga Richard
- Tanaka Hirohisa
- Tapia Oregui Beatriz
- Tapper Alexander
- Tariq Salman
- Tatar E.
- Tayloe Rex
- Teklu Abraham Meles
- Tenti Matteo
- Terao Kazuhiro
- Ternes Christoph
- Terranova Francesco
- Testera Gemma
- Thea Alessandro
- Thompson Joshua
- Thorn Craig
- Timm Steven C
- Todd Jacob
- Tonazzo Alessandra
- Torres de Mello Neto Joao
- Torti Marta
- Tortola Mariam
- Tortorici Francesco
- Totani Dante
- Toups Matthew
- Touramanis Christos
- Trevor Jason
- Trzaska Wladyslaw
- Tsai Yun-Tse
- Tsamalaidze Zviadi
- Tsang Ka Vang
- Tsverava Nikolozi
- Tufanli Serhan
- Tull Craig
- Tyley E.
- Tzanov Martin
- Uchida Melissa
- Urheim Jon
- Usher Tracy
- Vagins Mark R
- Vahle Patricia
- Valdiviesso Gustavo
- Valencia E.
- Vallari Zoya
- Valle Jose
- Vallecorsa Sofia
- Van Berg Rick
- Van de Water Richard
- Vanegas Forero David
- Varanini Filippo
- Vargas Danaisis
- Varner Gary
- Vasel Justin
- Vasseur Georges
- Vaziri Kamran
- Ventura Sandro
- Verdugo Antonio
- Vergani Stefano
- Vermeulen Milo
- Verzocchi Marco
- Vieira de Souza Henrique
- Vignoli Chiara
- Vilela Cristovao
- Viren Brett
- Vrba Tomas
- Wachala Tomasz
- Waldron Abigail
- Wallbank Michael
- Wang Hanguo
- Wang Jingbo
- Wang Yi
- Wang Yue
- Warburton Karl
- Warner David
- Wascko Morgan
- Waters David
- Watson Alan
- Weatherly Pierce
- Weber Alfons
- Weber Michele
- Wei Hanyu
- Weinstein Amanda
- Wenman Dan
- Wetstein Matthew
- While M.R.
- White Andy
- Whitehead Leigh
- Whittington Denver
- Wilking Michael
- Wilkinson Callum
- Williams Zachary
- Wilson Fergus
- Wilson Robert
- Wolcott Jeremy
- Wongjirad Taritree
- Wood Kevin
- Wood Lynn
- Worcester Elizabeth
- Worcester Matthew
- Wret Clarence
- Wu Wanwei
- Xiao Y.
- Yang Guang
- Yang Shaokai
- Yang Tingjun
- Yershov Nikolai
- Yonehara Katsuya
- Young Tim
- Yu Bo
- Yu Jae
- Zalesak Jaroslav
- Zambelli Laura
- Zamorano Bruno
- Zani Andrea
- Zazueta Luis
- Zeller G.P.
- Zeller Geralyn (Sam)
- Zennamo Joseph
- Zeug Kyle
- Zhang Chao
- Zhao Manhong
- Zhivun Elena
- Zhu Guanying
- Zimmerman Eric
- Zito Marco
- Zucchelli Stefano
- Zuklin Josef
- Zutshi Vishnu
- Zwaska Robert
- Publication venue
- HAL CCSD
- Publication date
- 07/02/2020
- Field of study
The preponderance of matter over antimatter in the early universe, the dynamics of the supernovae that produced the heavy elements necessary for life, and whether protons eventually decay -- these mysteries at the forefront of particle physics and astrophysics are key to understanding the early evolution of our universe, its current state, and its eventual fate. DUNE is an international world-class experiment dedicated to addressing these questions as it searches for leptonic charge-parity symmetry violation, stands ready to capture supernova neutrino bursts, and seeks to observe nucleon decay as a signature of a grand unified theory underlying the standard model. The DUNE far detector technical design report (TDR) describes the DUNE physics program and the technical designs of the single- and dual-phase DUNE liquid argon TPC far detector modules. Volume II of this TDR, DUNE Physics, describes the array of identified scientific opportunities and key goals. Crucially, we also report our best current understanding of the capability of DUNE to realize these goals, along with the detailed arguments and investigations on which this understanding is based. This TDR volume documents the scientific basis underlying the conception and design of the LBNF/DUNE experimental configurations. As a result, the description of DUNE's experimental capabilities constitutes the bulk of the document. Key linkages between requirements for successful execution of the physics program and primary specifications of the experimental configurations are drawn and summarized. This document also serves a wider purpose as a statement on the scientific potential of DUNE as a central component within a global program of frontier theoretical and experimental particle physics research. Thus, the presentation also aims to serve as a resource for the particle physics community at large
Deep Underground Neutrino Experiment (DUNE), Far Detector Technical Design Report, Volume I Introduction to DUNE
- Author
- Abi Babak
- Acciarri Roberto
- Acero Mario
- Adamov Giorge
- Adams David
- Adinolfi Marco
- Ahmad Zubayer
- Ahmed Jhanzeb
- Alion Tyler
- Alonso Monsalve Saul
- Alt Christoph
- Anderson John
- Andreopoulos Costas
- Andrews Michael P
- Andriamirado Manoa
- Andrianala Fenompanirina
- Andringa Sofia
- Ankowski Artur
- Anthony Jack
- Antoniu Iliescu
- Antonova Maria
- Antusch Stefan
- Aranda Fernandez Alfredo
- Ariga Akitaka
- Arnold Lukas
- Arroyave Manuel
- Asaadi Jonathan
- Aurisano Adam
- Aushev Vladimir
- Autiero Dario
- Azfar Farrukh
- Back Ashley
- Back Henning
- Back John
- Backhouse Chris
- Baesso Paolo
- Bagby Linda
- Bajou Raphael
- Balasubramanian Supraja
- Baldi Pierre
- Bambah Bindu
- Barao Fernando
- Barenboim Gabriela
- Barker Gary J
- Barkhouse Wayne
- Barnes Christopher
- Barr Giles
- Barranco Monarca Juan
- Barros Nuno
- Barrow Joshua
- Bashyal Amit
- Basque Vincent
- Bay Fatih
- Beacom John
- Bechetoille Edouard
- Behera Biswaranjan
- Bellantoni Leo
- Bellettini Giorgio
- Bellini Vincenzo
- Beltramello Olga
- Benekos Nektarios
- Bento Neves Francisco
- Berger Joshua
- Berkman Sophie
- Bernardini Paolo
- Berner Roman
- Berns Hans-Gerd
- Bertolucci Sergio
- Betancourt Minerba
- Bhattacharjee Maharnab
- Bhuyan Bipul
- Biagi Simone
- Bian Jianming
- Biassoni Matteo
- Biery Kurt
- Bilki Burak
- Bishai Mary
- Bitadze Alexander
- Blake Andrew
- Blanco Siffert Beatriz
- Blaszczyk Flor de Maria
- Blazey Gerald C
- Blucher Edward
- Boissevain Jan
- Bolognesi Sara
- Bolton Timothy
- Bonesini Maurizio
- Bongrand Mathieu
- Bonini Filiberto
- Booth Alexander
- Booth Chris
- Bordoni Stefania
- Borkum Aran
- Boschi Tommaso
- Bostan Nilay
- Bour Petr
- Boyd Steve B
- Boyden Daniel
- Bracinik Juraj
- Braga Davide
- Brailsford Dominic
- Brandt Andrew
- Bremer Johan
- Brew Chris
- Brianne Eldwan
- Brice Stephen
- Brizzolari Claudia
- Bromberg Carl
- Brooijmans Gustaaf
- Brooke Jim
- Bross Alan
- Brunetti Giulia
- Buchanan Norman
- Budd Howard
- Caiulo Davide
- Calafiura Paolo
- Calcutt Jacob
- Calin Marius
- Calvez Steven
- Calvo Enrique
- Camilleri Leslie
- Caminata Alessio
- Campanelli Mario
- Caratelli David
- Carini Gabriella
- Carlus Bruno
- Carniti Paolo
- Caro Terrazas Ivan
- Carranza Hector
- Castillo Andrés
- Castromonte Cesar
- Cattadori Carla
- Cavalier Fabien
- Cavanna Flavio
- Centro Sandro
- Cerati Giuseppe
- Cervelli Alberto
- Cervera Villanueva Anselmo
- Chalifour Michel
- Chardonnet Etienne
- Chatterjee Animesh
- Chattopadhyay Subhasish
- Chaves Jorge
- Chen Hucheng
- Chen Mu-Chun
- Chen Yifan
- Cherdack Daniel
- Chi Cheng-Yi
- Childress Sam
- Chiriacescu Ana
- Cho Kihyeon
- Choubey Sandhya
- Christensen Anne
- Christian David
- Christodoulou Georgios
- Church Eric
- Clarke Peter
- Coan Thomas
- Cocco Alfredo
- Coelho Joao
- Conley Erin
- Conrad Janet M
- Convery Mark
- Corwin Luke
- Cotte Philippe
- Cremaldi Lucien
- Cremonesi Linda
- Crespo-AnadĂłn Jose I
- Cristaldo Esteban
- Cross Ryan
- Cuesta Clara
- Cui Yanou
- Cussans David
- da Motta Helio
- Dabrowski Mieczyslaw
- David Quentin
- Davies Gavin
- Davini Stefano
- Dawson Jaime
- de Almeida Rogerio
- de Bonis Isabelle
- de Gouvea Andre
- de Holanda Pedro
- de Icaza Astiz Iker
- de Jong Paul
- de Lurgio Patrick
- de Roeck Albert
- de Romeri Valentina
- De Kaushik
- Debbins Paul
- Decowski M Patrick
- Deisting Alexander
- Delbart Alain
- Delepine David
- Delgado Maritza
- Dell'Acqua Andrea
- Demuth David
- Dennis Steve
- Densham Chris
- Dharmapalan Ranjan
- Di Domizio Sergio
- Di Giulio Letizia
- Di Noto Lea
- Diaz Felix
- Diaz Jorge S
- Ding Pengfei
- Distefano Carla
- Diurba Richard
- Diwan Milind
- Djurcic Zelimir
- Dokania Neha
- Dolinski Michelle J
- Domine Laura
- Douglas Daniel
- Drielsma Francois
- Duchesneau Dominique
- Duffy Kirsty
- Dunne Patrick
- Durkin Tim
- Duyang Hongyue
- Dvornikov Olexiy
- Dwyer Daniel A
- Dyshkant Alexandre S
- Eads Michael
- Edmunds Daniel
- Eisch Jonathan
- Emery Sandrine
- Ereditato Antonio
- Escobar Carlos O
- Escudero Sanchez Lorena
- Evans Justin
- Ewart Kevin
- Ezeribe Anthony
- Fahey Kevin
- Falcone Andrea
- Farnese Christian
- Farzan Yasaman
- Felix Julian
- Fernandez Menendez Pablo
- Fernandez-Martinez Enrique
- Ferraro Federico
- Fields Laura
- Filthaut Frank
- Fitzpatrick Rory
- Flanagan Will
- Fleming Bonnie
- Flight Robert
- Fowler Jack
- Fox Walt
- Franc Jiri
- Francis Kurt
- Franco Domenico
- Freeman John
- Freestone Julian
- Fried Jack
- Friedland Alex
- Fuess Stu
- Furic Ivan
- Furmanski Andrew
- Gallagher Hugh
- Gallego-Ros Ana
- Gallice Niccolo
- Galymov Vyacheslav
- Gamberini Enrico
- Gamble Trevor
- Gandhi Raj
- Gandrajula Reddy
- Gao Shanshan
- Garcia-Gamez Diego
- GarcĂa-Peris Miguel
- Gardiner Steven
- Gastler Dan
- Ge Guanqun
- Gelli Bruno
- Gendotti Adamo
- Gent Stephen
- Ghorbani-Moghaddam Zahra
- Gibin Daniele
- Gil-Botella Ines
- Girerd Claude
- Giri Anjan Kumar
- Gogota Olga
- Gold Michael
- Gollapinni Sowjanya
- Gollwitzer Keith
- Gomes Ricardo
- Gomez Bermeo Laura Vanessa
- Gomez Fajardo Luz
- Gonnella Francesco
- Gonzalez-Cuevas Juan Alberto
- Goodman Maury
- Goodwin Owen
- Goswami Srubabati
- Gotti Claudio
- Goudzovski Evgueni
- Grace Carl
- Graham Mathew
- Gran Rik
- Granados Everardo
- Grant Alan
- Grant Christopher
- Grant Nick
- Gratieri Diego
- Green Patrick
- Green Steven
- Greenler Leland
- Greer Joel
- Gregor Recalde Derlis
- Griffith Clark
- Groh Micah
- Grudzinski James
- Grzelak Katarzyna
- Gu Wenqiang
- Guarino Victor
- Guenette Roxanne
- Guglielmi Alberto
- Guo Bing
- Guthikonda K K
- Gutierrez Rafael
- Guzowski Pawel
- Guzzo Marcelo
- Gwon Sunwoo
- Habig Alec
- Hadavand Haleh
- Haenni Roger
- Hahn Alan
- Haigh Jennifer
- Haiston James
- Hamernik Thomas
- Hamilton Philip
- Han Jiyeon
- Harder Kristian
- Harris Debbie
- Hartnell Jeffrey
- Hasegawa Takyua
- Hatcher Robert
- Hazen Eric
- Heavey Anne
- Heeger Karsten
- Hennessy Karol
- Henry Sarah
- Hernandez Morquecho Miguel Angel
- Herner Kenneth
- Hertel Lars
- Hewes Jeremy
- Higuera Pichardo Aaron
- Hill Tony
- Hillier Stephen
- Himmel Alexander
- Hoff James
- Hohl Christian
- Holin Anna
- Hoppe Eric
- Horton-Smith Glenn
- Hostert Matheus
- Hourlier Adrien
- Howard Bruce
- Howell Ryan
- Huang Junting
- Huang Junying
- Hugon Justin
- Iles Gregory
- Illingworth Robert
- Ioannisian Ara
- Itay Ran
- Izmaylov Alexander
- James Eric
- Jan de Vries Joris
- Jediny Filip
- JesĂșs-Valls CĂ©sar
- Ji Xiangpan
- Jiménez Sergio
- Jipa Alexandru
- Johnson Connor
- Johnson Randy
- Jones Benjamin
- Jones Sebastian
- Jung Chang Kee
- Junk Thomas
- Jwa Yeon-Jae
- Kabirnezhad Monireh
- Kaboth Asher
- Kadenko I
- Kamiya Felipe
- Karagiorgi Georgia
- Karolak Mark
- Karyotakis Yannis
- Kasai Seiji
- Kasetti Siva
- Kashur Lane
- Kazaryan Narine
- Kearns Edward
- Keener Paul
- Kelly Kevin
- Kemp Ernesto
- Ketchum Wes
- Kettell Steve H
- Khabibullin Marat
- Khotjantsev Alexei
- Khvedelidze Arsen
- King Bonnie
- Kirby Brian
- Kirby Mike
- Klein Joshua
- Koehler Kevin
- Koerner Lisa
- Kohn Sam
- Koller Patrick
- Kordosky Mike
- Kosc Thomas
- Kose Umut
- Kostelecky V Alan
- Kothekar Kunal
- Krennrich Frank
- Kreslo Igor
- Kudenko Yury
- Kudryavtsev Vitaly A
- Kulagin Sergey
- Kumar Jason
- Kumar Rajeev
- Kuruppu Chatura
- Kus Vaclav
- Kutter Thomas
- Lande Kenneth
- Lane Charles
- Lang Karol
- Langford Thomas
- Lasorak Pierre
- Last David
- Lastoria Chiara
- Laundrie Andy
- Lazanu Ionel
- Lazur Ryan
- Le Trung
- Learned John
- Lebrun Patrice
- Lehmann Miotto Giovanna
- Lehnert Ralf
- Leigui de Oliveira M A
- Leyton Michael
- Li Lingge
- Li Shaorui
- Li Shirley W
- Li Teng
- Li Yichen
- Liao Heng-Ye
- Lin Cheng-Ju Stephen
- Lin Shih-Kai
- Lister Adam
- Littlejohn Bryce
- Lockwitz Sarah
- Loew Timothy
- Lokajicek Milos
- Lomidze Irakli
- Long Ken
- Loo Kai
- Lorca David
- Lord Tom
- Losecco John M
- Louis William
- Luk Kam-Biu
- Luo Xiao
- Lurkin Nicolas
- Lux Thorsten
- Luzio Vitor Prestes
- Macfarlane David
- Machado Ana Amelia
- Machado Pedro
- Macias Christopher Thomas
- Macier Jolie R
- Maddalena Antonello
- Madigan Peter
- Magill Steve
- Mahn Kendall
- Maio AmeÌlia
- Maloney James
- Mandrioli Gianni
- Maneira José
- Manenti Laura
- Manly Steve
- Mann Anthony
- Manolopoulos Konstantinos
- Manrique Plata Maria
- Marchionni Alberto
- Marciano William
- Marfatia Danny
- Mariani Camillo
- Maricic Jelena
- Marinho Franciole
- Marino Alysia
- Marshak Marvin
- Marshall Chris
- Marshall John
- Marteau Jacques
- Martin-Albo Justo
- Martinez Caicedo David
- Martinez Norman
- Martynenko Sergey
- Mason Katie
- Mastbaum Andrew
- Masud Mehedi
- Matsuno Shigenobu
- Matthews James
- Mauger Christopher
- Mauri Nicoletta
- Mavrokoridis Konstantinos
- Mazza Roberto
- Mazzacane Anna
- Mazzucato Edoardo
- Mccluskey Elaine
- Mcconkey Nicola
- Mcfarland Kevin
- Mcgrew Clark
- Mcnab Andrew
- Mefodiev Alexander
- Mehta Poonam
- Melas Pantelis
- Mellinato Michele
- Mena Olga
- Menary Scott
- Mendes Santos Lucas
- Mendez Hector
- Menegolli A
- Meng Guang
- Messier Mark
- Metcalf William
- Mewes Matthew
- Meyer Holger
- Miao Ting
- Michna Gregory
- Miedema Thijs
- Migenda Jost
- Milincic Radovan
- Miller William
- Mills Joshua
- Milne Cody
- Mineev Oleg
- Miranda Omar
- Miryala Sandeep
- Mishra C Shekhar
- Mishra Sanjib R
- Mislivec Aaron
- Mladenov Dimitar
- Mocioiu Irina
- Moffat Kristian
- Moggi Niccolo
- Mohanta Rukmani
- Mohayai Tanaz
- Mokhov Nikolai
- Molina Bueno Laura
- Molina Jorge
- Montanari Alessandro
- Montanari Claudio
- Montanari David
- Montano Zetina Luis
- Moon Jarrett
- Mooney Michael
- Moreno Deywis
- Morgan Ben
- Morris Casandra
- Mossey Chris
- Motuk Erdem
- Moura CĂ©lio
- Mousseau Joel
- Mu Wei
- Mualem Leon
- Mueller Justin
- Muether Mathew
- Mufson Stuart
- Muheim Franz
- Muir Alan
- Mulhearn Mike
- Muramatsu Hajime
- Murphy Sebastien
- Musser Jim
- Nachtman Jane
- Nalbandyan Mikayel
- Nandakumar Raja
- Naples Donna
- Narita Shinya
- Nayak Nitish
- Nebot-Guinot Miquel
- Necib Lina
- Negishi Kentaro
- Nelson Jeff
- Nesbit Jake
- Nessi Marzio
- Newbold David
- Newcomer Mitch
- Newhart Duane
- Nichol Ryan
- Niner Evan
- Nishimura Kurtis
- Norman Andrew
- Northrop Rich
- Novella Pau
- Nowak Jaroslaw
- Oberling Michael
- Olivares del Campo Andres
- Olivier Andrew
- Onel Yasar
- Onishchuk Yuriy
- Ott Jordan
- Pagani Luca
- Pakvasa Sandip
- Palamara Ornella
- Palestini Sandro
- Paley Jonathan
- Pallavicini Marco
- Palomares Carmen
- Pantic Emilija
- Paolone Vittorio
- Papadimitriou Vaia
- Papaleo Riccardo
- Papanestis Antonis
- Paramesvaran Sudarshan
- Parke Stephen
- Parsa Zohreh
- Parvu Mihaela
- Pascoli Silvia
- Pasqualini Laura
- Pasternak Jaroslaw
- Pater Joleen
- Patrick Cheryl
- Patrizii Laura
- Patterson Ryan
- Patton Simon John
- Patzak Thomas
- Paudel Ajib
- Paulos Bob
- Paulucci Laura
- Pavlovic Zarko
- Pawloski Greg
- Payne David
- Pec Viktor
- Peeters Simon
- Penichot Yves
- Pennacchio Elisabetta
- Penzo Aldo
- Peres Orlando
- Perry James
- Pershey Daniel
- Pessina Gianluigi
- Petrillo Gianluca
- Petta Catia
- Petti Roberto
- Piastra Francesco
- Pickering Luke
- Pietropaolo Francesco
- Pillow James
- Plunkett Robert
- Poling Ronald
- Pons Xavier
- Poonthottathil Navaneeth
- Pordes Stephen
- Potekhin Maxim
- Potenza Renato
- Potukuchi Baba
- Pozimski Juergen
- Pozzato Michele
- Prakash Suprabh
- Prakash Tarun
- Prince Sebastien
- Pugnere Denis
- Qian Xin
- Raaf Jennifer L
- Radeka Veljko
- Rademacker Jonas
- Radics Balint
- Rafique Aleena
- Raguzin Eric
- Rai Mousam
- Rajaoalisoa Miriama
- Rakhno Igor
- Rakotondravohitra Laza
- Ramachers Yorck A
- Rameika Regina
- Ramirez Delgado Manuel Alejandro
- Ramson Bryan
- Rappoldi A
- Raselli Gl
- Ratoff Peter
- Ravat Sylvain
- Real Jean-Sebastien
- Rebel Brian
- Redondo David
- Reggiani-Guzzo Marina
- Rehak Tyler
- Reichenbacher Juergen
- Reitzner S
- Renshaw Andrew
- Rescia Sergio
- Resnati Filippo
- Reynolds Aidan
- Riccobene Giorgio
- Rice Logan
- Rielage Keith
- Rigaut Yann-Axel
- Rivera David
- Rochester Leon
- Roda Marco
- Rodrigues Philip
- Rodriguez Alonso Manual Jesus
- Rodriguez Rondon Jairo
- Roeth Alison J
- Rogers Hannah
- Rosauro-Alcaraz Salvador
- Rossella M
- Rout Jogesh
- Roy Samiran
- Rubbia Andre
- Rubbia Carlo
- Russell Brooke
- Russell James
- Ruterbories Daniel
- Saakyan Ruben
- Sacerdoti Sabrina
- Safford Twymun
- Sahu Narendra
- Sala Paola
- Samios Nicholas
- Sanchez Mayly
- Sanders David
- Sankey David
- Santana Samuel
- Santos-Maldonado Marvin
- Saoulidou Niki
- Sapienza Piera
- Sarasty Carlos
- Sarcevic Ina
- Savage Geoffrey
- Savinov Vladimir
- Scaramelli Alberto
- Scarff Andrew
- Scarpelli Andrea
- Schaffer Tom
- Schellman Heidi
- Schlabach Philip
- Schmitz David
- Scholberg Kate
- Schukraft Anne
- Segreto Ettore
- Sensenig Jon
- Seong Ilsoo
- Sergi Antonino
- Sgalaberna Davide
- Shaevitz Michael H
- Shafaq Sheeba
- Sharma Hans
- Sharma Rahul
- Shaw Terri
- Shepherd-Themistocleous Claire
- Shin Seodong
- Shooltz Dean
- Shrock Robert
- Simard Laurent
- Simos Nikolaos
- Sinclair James
- Sinev Gleb
- Singh Jaydip
- Singh Jyotsna
- Sipos Roland
- Sippach F W
- Sirri Gabriele
- Sitraka Andriaseta
- Siyeon Kim
- Smith Adryanna
- Smith Andrew
- Smith Erica
- Smith Paul
- Smolik Jan
- Smy Michael
- Snopok Pavel
- Soares Nunes MĂŽnica
- Sobel Henry
- Soderberg Mitch
- Solano Salinas Carlos
- Solomey Nicholas
- Solovov Vladimir
- Sondheim Walter
- Sorel Michel
- Soto-Oton Jose
- Sousa Alexandre
- Soustruznik Karel
- Spagliardi Fabio
- Spanu Maura
- Spitz Joshua
- Spooner Neil Jc
- Spurgeon Kyle
- Staley Richard
- Stancari Michelle
- Stanco Luca
- Steiner Herbert M
- Stewart James
- Stillwell Ben
- Stock Jason
- Stocker Francesca
- Stokes Tyler
- Strait Matthew
- Strauss Thomas
- Striganov Sergei
- Stuart Alexander
- Summers Don
- Surdo Antonio
- Susic Vasja
- Suter Louise
- Sutera Concetta Maria
- Svoboda Robert
- Szczerbinska Barbara
- Szelc Andrzej
- Söldner-Rembold Stefan
- Talaga Richard
- Tanaka Hirohisa
- Tapia Oregui Beatriz
- Tapper Alexander
- Tariq Salman
- Tatar E.
- Tayloe Rex
- Teklu Abraham Meles
- Tenti Matteo
- Terao Kazuhiro
- Ternes Christoph
- Terranova Francesco
- Testera Gemma
- Thea Alessandro
- Thompson Joshua
- Thorn Craig
- Timm Steven C
- Todd Jacob
- Tonazzo Alessandra
- Torres de Mello Neto Joao
- Torti Marta
- Tortola Mariam
- Tortorici Francesco
- Totani Dante
- Toups Matthew
- Touramanis Christos
- Trevor Jason
- Trzaska Wladyslaw
- Tsai Yun-Tse
- Tsamalaidze Zviadi
- Tsang Ka Vang
- Tsverava Nikolozi
- Tufanli Serhan
- Tull Craig
- Tyley E.
- Tzanov Martin
- Uchida Melissa
- Urheim Jon
- Usher Tracy
- Vagins Mark R
- Vahle Patricia
- Valdiviesso Gustavo
- Vallari Zoya
- Valle Jose
- Vallecorsa Sofia
- van Berg Rick
- van de Water Richard
- Vanegas Forero David
- Varanini Filippo
- Vargas Danaisis
- Varner Gary
- Vasel Justin
- Vasseur Georges
- Vaziri Kamran
- Ventura Sandro
- Verdugo Antonio
- Vergani Stefano
- Vermeulen Milo
- Verzocchi Marco
- Vieira de Souza Henrique
- Vignoli Chiara
- Vilela Cristovao
- Viren Brett
- Vrba Tomas
- Wachala Tomasz
- Waldron Abigail
- Wallbank Michael
- Wang Hanguo
- Wang Jingbo
- Wang Yi
- Wang Yue
- Warburton Karl
- Warner David
- Wascko Morgan
- Waters David
- Watson Alan
- Weatherly Pierce
- Weber Alfons
- Weber Michele
- Wei Hanyu
- Weinstein Amanda
- Wenman Dan
- Wetstein Matthew
- White Andy
- Whitehead Leigh
- Whittington Denver
- Wilking Michael
- Wilkinson Callum
- Williams Zachary
- Wilson Fergus
- Wilson Robert
- Wolcott Jeremy
- Wongjirad Taritree
- Wood Kevin
- Wood Lynn
- Worcester Elizabeth
- Worcester Matthew
- Wret Clarence
- Wu Wanwei
- Yang Guang
- Yang Shaokai
- Yang Tingjun
- Yershov Nikolai
- Yonehara Katsuya
- Young Tim
- Yu Bo
- Yu Jae
- Zalesak Jaroslav
- Zambelli Laura
- Zamorano Bruno
- Zani Andrea
- Zazueta Luis
- Zeller Geralyn
- Zennamo Joseph
- Zeug Kyle
- Zhang Chao
- Zhao Manhong
- Zhivun Elena
- Zhu Guanying
- Zimmerman Eric
- Zito Marco
- Zucchelli Stefano
- Zuklin Josef
- Zutshi Vishnu
- Zwaska Robert
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2020
- Field of study
International audienceThe preponderance of matter over antimatter in the early universe, the dynamics of the supernovae that produced the heavy elements necessary for life, and whether protons eventually decayâthese mysteries at the forefront of particle physics and astrophysics are key to understanding the early evolution of our universe, its current state, and its eventual fate. The Deep Underground Neutrino Experiment (DUNE) is an international world-class experiment dedicated to addressing these questions as it searches for leptonic charge-parity symmetry violation, stands ready to capture supernova neutrino bursts, and seeks to observe nucleon decay as a signature of a grand unified theory underlying the standard model. The DUNE far detector technical design report (TDR) describes the DUNE physics program and the technical designs of the single- and dual-phase DUNE liquid argon TPC far detector modules. This TDR is intended to justify the technical choices for the far detector that flow down from the high-level physics goals through requirements at all levels of the Project. Volume I contains an executive summary that introduces the DUNE science program, the far detector and the strategy for its modular designs, and the organization and management of the Project. The remainder of Volume I provides more detail on the science program that drives the choice of detector technologies and on the technologies themselves. It also introduces the designs for the DUNE near detector and the DUNE computing model, for which DUNE is planning design reports. Volume II of this TDR describes DUNE's physics program in detail. Volume III describes the technical coordination required for the far detector design, construction, installation, and integration, and its organizational structure. Volume IV describes the single-phase far detector technology. A planned Volume V will describe the dual-phase technology