23 research outputs found
Energieverluste durch Bindedrähte in einer Turbinenstufe
Der zur Schwingungsdämpfung der Schaufeln eingesetzte Bindedraht vermindert die Leistungsfähigkeit der Turbinenstufe erheblich. Wo man Bindedrähte in zwei oder drei Reihen anbringen muß, kann die Minderung dadurch einige Prozent ausmachen.
Die großen Energieverluste aufgrund der Bindedrähte machen ihren Einsatz nicht immer sinnvoll. Die Schweizer Firma Escher Wyss AG setzt sie überhaupt nicht ein, weil sie annimmt, daß die Bindedrähte die Leistungsfähigkeit stark vermindern und in einigen Fällen der Grund dafür sind, daß die nachfolgenden Stufen stärker verschleißen. Deshalb ist die richtige Abschätzung der Energieverluste infolge vorhandener Bindedrähte von großer praktischer Bedeutung. Gleichzeitig sind uns nur wenige Versuche bekannt, die auf die Bestimmung dieser Energieverluste abzielten. Nachfolgend werden einige Versuchsergebnisse dargelegt, die im Transportmaschinenbau-Institut Brjansk durchgeführt wurden
ERA5 reanalysis for the data interpretation on polarization laser sensing of high-level clouds
Interpreting the results of a high-level clouds (HLCs) lidar study requires a comparison with the vertical profiles of meteorological quantities. There are no regular radiosonde measurements of vertical profiles of meteorological quantities in Tomsk. The nearest aerological stations are several hundred kilometers away from the lidar and perform radiosonde measurements only a few times a day, whereas lidar experiments are performed continuously throughout the day. To estimate meteorological conditions at the HLC altitudes, we propose to use the ERA5 reanalysis. Its reliability was tested by comparing with the data from five aerological stations within a radius of 500 km around Tomsk. A labeled database of the lidar, radiosonde, and ERA5 data (2016–2020) for isobaric levels 1000–50 hPa was created. The temperature reconstruction error over the entire altitude range was characterized by an RMSE of 0.8–2.8 ◦C, bias of 0–0.9, and Corr ~1. The accuracy of the relative vertical profiles (RMSE 25–40%, Bias 10–22%, and Corr <0.7) and specific humidity (RMSE 0.2–1.2 g/kg, Bias ~0 g/kg, and Corr ~0) at the HLC altitudes were unsatisfying. The ERA5 data on wind direction and speed for the HLC altitudes were promising
Toward a warmer Arctic Ocean: Spreading of the early 21st century Atlantic Water warm anomaly along the Eurasian Basin margins
We document through the analysis of 2002–2005 observational data the recent Atlantic Water (AW) warming along the Siberian continental margin due to several AW warm impulses that penetrated into the Arctic Ocean through Fram Strait in 1999–2000. The AW temperature record from our long-term monitoring site in the northern Laptev Sea shows several events of rapid AW temperature increase totaling 0.8°C in February–August 2004. We hypothesize the along-margin spreading of this warmer anomaly has disrupted the downstream thermal equilibrium of the late 1990s to earlier 2000s. The anomaly mean velocity of 2.4–2.5 ± 0.2 cm/s was obtained on the basis of travel time required between the northern Laptev Sea and two anomaly fronts delineated over the Eurasian flank of the Lomonosov Ridge by comparing the 2005 snapshot along-margin data with the AW pre-1990 mean. The magnitude of delineated anomalies exceeds the level of pre-1990 mean along-margin cooling and rises above the level of noise attributed to shifting of the AW jet across the basin margins. The anomaly mean velocity estimation is confirmed by comparing mooring-derived AW temperature time series from 2002 to 2005 with the downstream along-margin AW temperature distribution from 2005. Our mooring current meter data corroborate these estimations
Emotions in Positum
The article aims to develop a definition of emotions that would be both theoretically and practically applicable in psychotherapy (prescriptive), while also aligning with the everyday (descriptive) understanding of the term. The arguments are grounded on sound review of relevant theories that help to grasp the somatic and psychological mechanisms that enable the experience and utilization of emotions. Emotions are differentiated from feelings and stress. The intratheoretical consistency of the newly formulated understanding of emotions with the model of conflictogenesis of positive psychotherapy has been demonstrated
Application of the Balance Model in the Analysis of Factors Responsible for Depressive Disorders among Women in the COVID-19 Pandemic
The COVID-19 pandemic has significantly affected the lives and mental health of people around the world, and it has become clinically essential to define risk factors in order to provide adequate prevention and support. The aim of the study was to describe coping strategies in Polish women related to the COVID-19 pandemic using the balance model, one of the most important concepts of positive psychotherapy (PPT after Peseschkian since 1977). The analysis included 735 women at the mean age of 39.61 years. The survey was conducted using the questionnaire form on the website. Based on Beck’s depression test, depressive disorders were disclosed in 32.65%, and both the presence and severity of depressive syndromes were inversely correlated with age. Using a cluster analysis, three adaptation strategies could be identified, related to the different prevalence of depressive disorders. Relationships proved the most crucial area of the balance model, responsible for the effectiveness of the coping strategy. Based on the obtained results, it has to be concluded that preventive measures should primarily concern women aged < 25 years old and focus on strengthening the relationships area
Distribution of the invasive plant species Heracleum sosnowskyi Manden. in the Komi Republic (Russia)
Volume: 77Start Page: 71End Page: 8
Nucleoside Analogs That Inhibit SARS-CoV-2 Replication by Blocking Interaction of Virus Polymerase with RNA
The SARS-CoV-2 betacoronavirus pandemic has claimed more than 6.5 million lives and, despite the development and use of COVID-19 vaccines, remains a major global public health problem. The development of specific drugs for the treatment of this disease remains a very urgent task. In the context of a repurposing strategy, we previously screened a library of nucleoside analogs showing different types of biological activity against the SARS-CoV-2 virus. The screening revealed compounds capable of inhibiting the reproduction of SARS-CoV-2 with EC50 values in the range of 20–50 µM. Here we present the design and synthesis of various analogs of the leader compounds, the evaluation of their cytotoxicity and antiviral activity against SARS-CoV-2 in cell cultures, as well as experimental data on RNA-dependent RNA polymerase inhibition. Several compounds have been shown to prevent the interaction between the SARS-CoV-2 RNA-dependent RNA polymerase and the RNA substrate, likely inhibiting virus replication. Three of the synthesized compounds have also been shown to inhibit influenza virus. The structures of these compounds can be used for further optimization in order to develop an antiviral drug